PFTAIRE2_Hsap MGQELCAK-------------------TV--QPGC---SCYHCSEG--------------
PFTAIRE1_Hsap MCDLIEPQ-------------------P--------------------------------
Eip63E_Dmel MAELISQP-------------------TK--I-NN--N-NF---------GAGVT---MR
PFTAIRE2_Mmus MGQELCAK-------------------RL--QPGC---SCYHRSEG--------------
PFTAIRE1_Mmus MCDLIEPQ-------------------P--------------------------------
pct-1_Cele MKKLKR-----------------RLSAAF--RPGSNN-NVSITSSGGSY----------Y
Pftaire_Spur MPILVPTI-------------------LT--M----------------------------
AqueK104_Aque MAATDSVFVDNVFYDYHSQQIKQHMDLVVEGGPGVEENSYRKRSSGGVNGGLEVFIEEKQ
*
PFTAIRE2_Hsap -----GE-------AHSC------RRSQPET-TEAA-FKLTDL--KEASC----------
PFTAIRE1_Hsap AEK-IGK-------MKKL------RRTLSESFSRIA-LKKDDT--TFDEI----------
Eip63E_Dmel EKK-GGA-------LQKL------KKRLSHSFGRLT-ISREDG--DESTHH---------
PFTAIRE2_Mmus -----GE-------AHSC------QRSQPGS-TEPAVFE---L--TEASS----------
PFTAIRE1_Mmus AEK-IGK-------MKKL------RRTLSESFSRIA-LKKEDT--TFDEI----------
pct-1_Cele DSDCEGRNNIVIGYGMMSAPLHGRTWTLSESMSHLS-DK-NGA--ILEECAVVDPTALLR
Pftaire_Spur ------------------------------------------------------------
AqueK104_Aque EEE-EGD-------GEES------RSSVST--TQTS-LKVNGYQARGNSL----------
PFTAIRE2_Hsap ---------------------------SMTSFHPRGLQA---------------------
PFTAIRE1_Hsap ---------------------------CVTKMSTRNCQGM---------------DS---
Eip63E_Dmel ---------------------------HHHHHHHRGGHGGHHNHGNKVPYNGYNSEE---
PFTAIRE2_Mmus ---------------------------STASFHPRGLEA---------------------
PFTAIRE1_Mmus ---------------------------CVTKMSTRNCQGT---------------DS---
pct-1_Cele VSRGGTAGRRYDTNVNYINGMHVPPPRTHSLYYPRGYNSR---------------RNSYY
Pftaire_Spur ------------------------------------------------------------
AqueK104_Aque ---------------------------SPMKRHSGGEQEL---------------YA---
PFTAIRE2_Hsap ------------------------------------ARAQ-KFK-------------S--
PFTAIRE1_Hsap ---------------------------VIKPLDT-IPEDK-KVR-------------V--
Eip63E_Dmel --------------Y----------LDRLEPNGN-IPADKTNCRYGDWRSTDSTDHHDRV
PFTAIRE2_Mmus ------------------------------------ASAQ-KLK-------------S--
PFTAIRE1_Mmus ---------------------------VIKHLDT-IPEDK-KVR-------------V--
pct-1_Cele GSNASVVQESMILGSDGESVEVSPCTSDQTPTGVPPRYIV-NVK-------------M--
Pftaire_Spur ------------------------------------P--KSSTR------------RARF
AqueK104_Aque -------------AQ----------NGEIKPTPS-PRHEP-KQK-------------SR-
. :
PFTAIRE2_Hsap KRPRS--NSDCFQEEDL-------------------------------------------
PFTAIRE1_Hsap QRTQS--TFDPFEK---------------------------PANQVKRVHSENNACINFK
Eip63E_Dmel QRQLSVSSDSKLLDEDIREE-MK---YHSHVVMRPKK-PPRPKSEV--------------
PFTAIRE2_Mmus KRPRS--NSDSFQEENL-------------------------------------------
PFTAIRE1_Mmus QRTQS--TFDPFEK---------------------------PANQVKRVHSENNACINFK
pct-1_Cele RQK--TARKWSEEEIQKRL-SLPADLR-------------LPVA-----------VVDKL
Pftaire_Spur I--------------------------------KP-------LPVM--------------
AqueK104_Aque SRPVS--LSISGKPPGLRRNSIPITASSSNDAIGPKPDIVRPIPAFRSTGSISNAVLINH
PFTAIRE2_Hsap ----------------------RQG---FQW-RKSLPFGAASSYLNLEKLGEGSYATVYK
PFTAIRE1_Hsap TSSTGK----------ESPKVRRHS---SPSSPTSPKFGKADSYEKLEKLGEGSYATVYK
Eip63E_Dmel --FLNK----------QETHPRRKR---FSAFGGDSPFGKQEAYVKLEPLGEGSYATVYK
PFTAIRE2_Mmus ----------------------RQG---LPW-KKSLPFGAASSYLNLEKLGEGSYAKVYK
PFTAIRE1_Mmus SSSAGK----------ESPKVRRHS---SPSSPTSPKFGKADSYEKLEKLGEGSYATVYK
pct-1_Cele NR--TP--------TLDQPLT-RKN---RRASLSEIGFGKLETYEKLDKLGEGTYATVFR
Pftaire_Spur --VTGP----------TCNHKRFGK---SPYCKSCSPFGKVETYKKICPLGEGSYAKVYK
AqueK104_Aque TSTTGSVAGGGTGNSLLLPNQRRFSTSNAPLSPLGSPFGRLETYKKLEALGEGSYATVYK
** .:* :: ****:**.*::
PFTAIRE2_Hsap GISRINGQLVALKVISMNAEEGVPFTAIRE-----ASLLKGLKHANIVLLHDIIHTKETL
PFTAIRE1_Hsap GKSKVNGKLVALKVIRLQEEEGTPFTAIRE-----ASLLKGLKHANIVLLHDIIHTKETL
Eip63E_Dmel GFSKLTYQRVALKEIRLQEEEGAPFTAIRE-----ASLLKELKHSNIVTLHDIVHTRETL
PFTAIRE2_Mmus GISRINGQLVALKVISMNAEEGVPFTAIRE-----ASLLKGLKHANIVLLHDIVHTKETL
PFTAIRE1_Mmus GKSKVNGKLVALKVIRLQEEEGTPFTAIRE-----ASLLKGLKHANIVLLHDIIHTKETL
pct-1_Cele GRSILTNKFVALKEIRLEQEEGAPCTAIRE-----VSLLRNLRHANVVTLHDIIHTDRLL
Pftaire_Spur AVSCINQQVVALKEIRLQQDEGTPFTAIRE-----ASLLKDLKHANIVCLHDIIHTKTTL
AqueK104_Aque GISIANGHYVALKEIRLNSEEGTPFTAIREGIMTFASLLKGLKHANIVILHDIIHTSNNL
. * . : **** * :: :**.* ***** .***: *:*:*:* ****:** *
PFTAIRE2_Hsap TFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISH
PFTAIRE1_Hsap TLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISD
Eip63E_Dmel TFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISD
PFTAIRE2_Mmus TFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQRVLHRDLKPQNLLLSH
PFTAIRE1_Mmus TLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISD
pct-1_Cele TLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITA
Pftaire_Spur SFVFEYVHTDLSTYLERHPGGLNPNNVRLFLFQLIRGLSFCHKRKILHRDLKPQNLLISE
AqueK104_Aque TFVFEYVDTDLSRYMEKHPGPLDPRNVKILLIQLLRGLNFCHRRKILHRDLKPQNILLNH
::****:. ** *:. . :. *::::: **:*** : *:: :****:****:*:.
PFTAIRE2_Hsap LGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMF
PFTAIRE1_Hsap TGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMI
Eip63E_Dmel CGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMV
PFTAIRE2_Mmus LGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMF
PFTAIRE1_Mmus TGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMI
pct-1_Cele KGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMI
Pftaire_Spur AGELKLADFGLARAKSIPSRTYSHEVVTLWYRPPDVLMGSTDYSTQLDIWGVGCIFLEMM
AqueK104_Aque NGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYFTSLDMWGVGCIFVEML
***************:*::*** ***********.*:*:*:* : :*:**.***:.**.
PFTAIRE2_Hsap QGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEW--FPLPTPRSLHVVWN
PFTAIRE1_Hsap QGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPER--FTLYSSKNLRQAWN
Eip63E_Dmel TGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHK--LGFYRPRKLGHNFP
PFTAIRE2_Mmus QGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEW--FPPPKPQSLQIVWD
PFTAIRE1_Mmus QGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPER--FTVYSSKSLRQAWN
pct-1_Cele AGRALFPGGTP-TEQLGLIFRTLGSPRPDRHPTICEKPTFYPYA--NRHYNPDPLCRQIP
Pftaire_Spur WGQPAFPGLKDATDQLEKIFKVLGTPTEQTWHGVSRLPNYGKVAAAGRFHKPKLLCEILP
AqueK104_Aque TGKPLFPGLKGVYDQLNRIWSILGTPNNTTWPGVTDLPEYRPEQ--YEQCPPLGLEVVAP
* . *** :** *: ** * : * : . *
PFTAIRE2_Hsap RLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRLK
PFTAIRE1_Hsap KLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQ
Eip63E_Dmel RLYDIIEGETIANGFLQLNPEQRLGADDALQHPYFAQLPKKLYELPDGENLNFHRGRRAA
PFTAIRE2_Mmus RLGGVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSVLPSQLYQLPDEESLFAVSGVKLK
PFTAIRE1_Mmus KLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQ
pct-1_Cele RID--AHGFELLMKFLQYEGKDRVSAAEAVKHPFLRTIAVKCCHLRDEQSVLEADGIHIE
Pftaire_Spur SILLIPGAESLMTDMLQLEPRKRISTVQAMTCQYFKDLPPKIFDLPPGASVFNVPGMKLE
AqueK104_Aque ILHPKTKVGDLAMKLLQLIPSNRITADDALAHEYFSSLPPAIFALPESASVFLIPGVLFN
: : :*: .*: : *: :: :. * .: .
PFTAIRE2_Hsap PEMCDLLASYQKGHHP----------AQFSKCW
PFTAIRE1_Hsap PEAGESMRAFGKNNSYGK--------SLSNSKH
Eip63E_Dmel LHG-------------------------AKSTE
PFTAIRE2_Mmus PEMCDLSASYRKRHHL----------VGVNKCW
PFTAIRE1_Mmus PEAGESMRAFGKNNSYGK--------SLSNSKH
pct-1_Cele RELLASDHHHSSRRHHRGTLVKDKYRMHSSHHT
Pftaire_Spur PEK-------------------------NNLSK
AqueK104_Aque --------------------------------R