Protein (view, download) , Domain (view, download)
TGFbR2_Hsap_STKR2    MGRGLLRGL---WPLH-IVL--WTRIASTI------------------------------
TGFbR1_Hsap_STKR1    MEAAVAAPR---PRLL-LLV--LAAAAAAA------------------------------
MISR2_Hsap_STKR2     MLGSLGL--------W-AL---LPTAVEAP------------------------------
MISR2_Mmus_STKR2     MLGTLGL--------W-TL---LPAAAQVS------------------------------
BMPR2_Mmus_STKR2     MTSSLHRPFRVPWLLW-AVL--LVSTTAAS------------------------------
BMPR1B_Mmus_STKR1    MLLRSSG-----KLN-------VGTK----------------------------------
BMPR1A_Mmus_STKR1    MTQLYTYIR---LLGA-CLF--IISHVQGQ-NL---------------------------
ALK7_Mmus_STKR1      MTPARGSAL-----SL-ALL--LVALAAD-------------------------------
ALK4_Mmus_STKR1      MAESAGASS---FFPL-VVL--LLAGSGGS------------------------------
ALK2_Mmus_STKR1      MVDGVMILP---VL-M--MM--AFPSPSVE------------------------------
ALK1_Mmus_STKR1      MTLGSFRRG---LL-M-LSV--AFGLTRGD------------------------------
ACTR2B_Mmus_STKR2    MTAPWAA-----L-AL-LW----GSLCAGS------------------------------
ACTR2_Mmus_STKR2     MGAAAKLA----F-AV-FL----ISCSSGA------------------------------
daf-4_Cele_STKR2     MNQKGTVR----LKALV-LICLPLFLIATP------------------------------
daf-1_Cele_STKR1     MRIRHVVFC---L--L-ALV--YGAETSDD------------------------------
BMPR1A_Hsap_STKR1    MPQLYIYIR---LLGA-YLF--IISRVQGQ-NL---------------------------
BMPR1B_Hsap_STKR1    MLLRSAG-----KLN-------VGTK----------------------------------
BMPR2_Hsap_STKR2     MTSSLQRPWRVPWLPW-TIL--LVSTAAAS------------------------------
ALK7_Hsap_STKR1      MTRALCSAL-----RQ-ALL--LLAAAAE-------------------------------
ALK4_Hsap_STKR1      MAESAGASS---FFPL-VVL--LLAGSGGS------------------------------
tkv_Dmel_STKR1       MGSEFSANV---QPDV-EAM--AAAALSGMEM----------------------------
put_Dmel_STKR2       MSKYDLLY----LTAQLTLVCCLIGI-HGS------------------------------
SAX_Dmel_STKR1       MESNIYLVF---LL-T--FL--LYNNARAE------------------------------
wit_Dmel_STKR2       MNWAIYL-------LL-ALI--SLGRATPV------------------------------
BABO_Dmel_STKR1      MLSALRLI------FL-GAL--LGASVCAS------------------------------
TGFBR1_Mmus_STKR1    MEAAAAAPR---RPQL-LIV--LVAAAT--------------------------------
TGFBR2_Mmus_STKR2    MGRGLLRGL---WPLH-IVL--WTRIASTI------------------------------
sma-6_Cele_STKR1     MNITFIFIL------I-FGF--FNTQKCSK------------------------------
ALK2_Hsap_STKR1      MVDGVMILP---VL-I--MI--ALPSPSME------------------------------
ALK1_Hsap_STKR1      MTLGSPRKG---LL-M-LLM--AL-VTQGD------------------------------
ACTR2B_Hsap_STKR2    MTAPWVA-----L-AL-LW----GSLCAGS------------------------------
ACTR2_Hsap_STKR2     MGAAAKLA----F-AV-FL----ISCSSGA------------------------------
TGFbR1_Spur_STKR1    MEIIG-------------------------------------------------------
ALK2_Spur_STKR1      MRASQDVYV--------ADL--AHQV----------------------------------
BMPR1_Spur_STKR1     MSYTYMRYY---EVLA-T------------------------------------------
TGFbRII_Spur_STKR2   MAYDVETDE---NNVP-FVV--TVSLGVAS------------------------------
ACTR2_Spur_STKR2     MAGKDPLIR---LCELFLFLSIAVLLVEGA------------------------------
BMPR2_Spur_STKR2     MHSSEHGDYTGKVIS--VIT--I-EAEIAE------------------------------
AqueK680_Aque_STKR1  LPF------------I-TSE--ITSATHSHT-----------------------------
AqueK681_Aque_STKR1  MIILILILF---L--L-SPL--IISGTTGV------------------------------
AqueK682_Aque_STKR1  MSH---------------------------------------------------------
AqueK683_Aque_STKR2  MAELRILVF---C--L-LAL--LLPVPS--------------------------------
AqueK684_Aque_STKR2  MCVYLKTSD---VF-I-KCF--STACPGGA-DICIELCPEGINKCHTVRRTNSYPVEMRC
AqueK685_Aque_STKR2  MINVTLFI--------------DPPDEA--------------------------------
AqueK686_Aque_STKR2  MVAVLRVVL---CF-C--LL--STIVTA--------------------------------
                     :

TGFbR2_Hsap_STKR2    ---------------------------------------------------PPH------
TGFbR1_Hsap_STKR1    ----------------------------------------------------A-------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ------------------------------------------------------------
BMPR1B_Mmus_STKR1    ----------------------KE------------------------DGEST-------
BMPR1A_Mmus_STKR1    -DSMLHGTGMKS----DLDQKKPE------------------------NGVTL-------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ----------------------------------------------------G-------
ALK2_Mmus_STKR1      ---------------------------------------------------DE-------
ALK1_Mmus_STKR1      ---------------------------------------------------LA-------
ACTR2B_Mmus_STKR2    ---------------------------------------------------GR-------
ACTR2_Mmus_STKR2     ---------------------------------------------------IL-------
daf-4_Cele_STKR2     ---------------------------------------------------VP-------
daf-1_Cele_STKR1     ----------------DLDERT--------------------------N-----------
BMPR1A_Hsap_STKR1    -DSMLHGTGMKS----DSDQKKSE------------------------NGVTL-------
BMPR1B_Hsap_STKR1    ----------------------KE------------------------DGEST-------
BMPR2_Hsap_STKR2     ------------------------------------------------------------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ----------------------------------------------------G-------
tkv_Dmel_STKR1       ------GSGPGSEGYEDADN------------------------------EKS-------
put_Dmel_STKR2       ---------------------------------------------------IL-------
SAX_Dmel_STKR1       ---------------------------------------------------IS-D-----
wit_Dmel_STKR2       ------------------------------------------------------------
BABO_Dmel_STKR1      ----------------------------------------------------PIEFVMDT
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ---------------------------------------------------PPH------
sma-6_Cele_STKR1     ----------------DYDHFDDEDLALSIPKNAIGVPKEFRQQVLKEMKLRN-------
ALK2_Hsap_STKR1      ---------------------------------------------------DE-------
ALK1_Hsap_STKR1      ---------------------------------------------------PV-------
ACTR2B_Hsap_STKR2    ---------------------------------------------------GR-------
ACTR2_Hsap_STKR2     ---------------------------------------------------IL-------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ---------------------------------------------------A--------
ACTR2_Spur_STKR2     ---------------------------------------------------SV-------
BMPR2_Spur_STKR2     ------------------------------------------------------------
AqueK680_Aque_STKR1  ---------------------------------------------------RS-------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  TN----------------------------------TPSCS-----------Q----SSD
AqueK685_Aque_STKR2  EN----------------------------------APSSF-----------H----VTD
AqueK686_Aque_STKR2  ------------------------------------FQC-------------R----VNS


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ------------------------------------------------------------
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     ------------------------------------------------------------
daf-1_Cele_STKR1     --------------------------------------------------IFI-------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ------------------------------------------------------------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       --------------------------------HLREDIPDLDMELSSASSAHL-------
wit_Dmel_STKR2       ------------------------------------------------------------
BABO_Dmel_STKR1      SLNGSRSDPATATHPGKWPPTTKAPALRAPAGTAGHAYQSPSSSLAADNRSHDNNNASAV
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     ------------------------------------------------------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  CV--------------------------------FETLQNFHSLHYCCCT----------
AqueK685_Aque_STKR2  QI-------------------------------------------TSSIE----------
AqueK686_Aque_STKR2  CI-------------------------------------------RCSSS----------


TGFbR2_Hsap_STKR2    ------------------------------VQ--KSDVEMEAQKDEIICPSCNRTAHPLR
TGFbR1_Hsap_STKR1    ------------------------------AL--L-------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ------------------------------------------------------------
BMPR1B_Mmus_STKR1    ------------------------------AP--T-------------------------
BMPR1A_Mmus_STKR1    ------------------------------AP--E-------------------------
ALK7_Mmus_STKR1      -------------------------------L--A-------------------------
ALK4_Mmus_STKR1      ----------------------------------P-------------------------
ALK2_Mmus_STKR1      ------------------------------KP--K-------------------------
ALK1_Mmus_STKR1      ------------------------------KP--S-------------------------
ACTR2B_Mmus_STKR2    ----------------------------------G-------------------------
ACTR2_Mmus_STKR2     ----------------------------------G-------------------------
daf-4_Cele_STKR2     -------------------------------VAVT-------------------------
daf-1_Cele_STKR1     ------R----DKLIPA----LK--LAEV-TK--V-------------------------
BMPR1A_Hsap_STKR1    ------------------------------AP--E-------------------------
BMPR1B_Hsap_STKR1    ------------------------------AP--T-------------------------
BMPR2_Hsap_STKR2     ------------------------------------------------------------
ALK7_Hsap_STKR1      -------------------------------L--S-------------------------
ALK4_Hsap_STKR1      ----------------------------------P-------------------------
tkv_Dmel_STKR1       ------------------------------KT--V-------------------------
put_Dmel_STKR2       -------------------------------P--G-------------------------
SAX_Dmel_STKR1       ------N----GKELPA-------------VP--Q-------------------------
wit_Dmel_STKR2       ------------------------------------------------------------
BABO_Dmel_STKR1      SMLLPQDGDASGAVAPAVTPQLPIYIAQP-SA--K-------------------------
TGFBR1_Mmus_STKR1    -------------------------------L--L-------------------------
TGFBR2_Mmus_STKR2    ------------------------------VP--KSDVEMEAQKDASIHLSCNRTIHPLK
sma-6_Cele_STKR1     ------------------------------RP--N-------------------------
ALK2_Hsap_STKR1      ------------------------------KP--K-------------------------
ALK1_Hsap_STKR1      ------------------------------KP--S-------------------------
ACTR2B_Hsap_STKR2    ----------------------------------G-------------------------
ACTR2_Hsap_STKR2     ----------------------------------G-------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------N-----------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------F-----------------------------
ACTR2_Spur_STKR2     -------------------------------N--L-------------------------
BMPR2_Spur_STKR2     ------------------------------------------------------------
AqueK680_Aque_STKR1  ------------------------------LP--L-------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  GDLCNRLDNYTDSVDPI----LNVTSAIPTVP--V-------------------------
AqueK685_Aque_STKR2  ---------------PS----LS--MIPSTVP--A-------------------------
AqueK686_Aque_STKR2  ---------------SP----V----DCTVTP--V-------------------------


TGFbR2_Hsap_STKR2    HINNDMIVTDNNG-----------------------------------------------
TGFbR1_Hsap_STKR1    -----------PG-----------------------------------------------
MISR2_Hsap_STKR2     ------------P-----------------------------------------------
MISR2_Mmus_STKR2     ------------P-----------------------------------------------
BMPR2_Mmus_STKR2     ------------Q-----------------------------------------------
BMPR1B_Mmus_STKR1    -----------PR-----------------------------------------------
BMPR1A_Mmus_STKR1    -----------DT-----------------------------------------------
ALK7_Mmus_STKR1      -----------A------------------------------------------------
ALK4_Mmus_STKR1      -----------RG-----------------------------------------------
ALK2_Mmus_STKR1      -----------VN-----------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------E-----------------------------------------------
ACTR2_Mmus_STKR2     ------------R-----------------------------------------------
daf-4_Cele_STKR2     ------------EDDRQDRIESEAAEKEWANTLVSKVAQSNGTGTIKVSAPAKPTLRRMD
daf-1_Cele_STKR1     -----------NF-----------------------------------------------
BMPR1A_Hsap_STKR1    -----------DT-----------------------------------------------
BMPR1B_Hsap_STKR1    -----------PR-----------------------------------------------
BMPR2_Hsap_STKR2     ------------Q-----------------------------------------------
ALK7_Hsap_STKR1      -----------P------------------------------------------------
ALK4_Hsap_STKR1      -----------RG-----------------------------------------------
tkv_Dmel_STKR1       -----------EN-----------------------------------------------
put_Dmel_STKR2       ------------S-----------------------------------------------
SAX_Dmel_STKR1       --------NSVQT-----------------------------------------------
wit_Dmel_STKR2       ------------P-----------------------------------------------
BABO_Dmel_STKR1      -----------KP-----------------------------------------------
TGFBR1_Mmus_STKR1    -----------PG-----------------------------------------------
TGFBR2_Mmus_STKR2    HFNSDVMASDNGG-----------------------------------------------
sma-6_Cele_STKR1     ------------D-----------------------------------------------
ALK2_Hsap_STKR1      -----------VN-----------------------------------------------
ALK1_Hsap_STKR1      ------------R-----------------------------------------------
ACTR2B_Hsap_STKR2    ------------E-----------------------------------------------
ACTR2_Hsap_STKR2     ------------R-----------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------N-----------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------P-----------------------------------------------
BMPR2_Spur_STKR2     ------------L-----------------------------------------------
AqueK680_Aque_STKR1  -----------PP-----------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  -----------P---------------------------------------VRP------
AqueK685_Aque_STKR2  -----------P------------------------------------------------
AqueK686_Aque_STKR2  -----------D------------------------------------------------


TGFbR2_Hsap_STKR2    -----AVKFPQLCKFCD------VRFS-TC---DNQK-S-----------C--MS-NCSI
TGFbR1_Hsap_STKR1    -----ATA--LQCF-CH------L-----C---T------------------------KD
MISR2_Hsap_STKR2     -----N-R--RTCVF-F-------EAP-GV---RG--STKTLGELL----DT--GTELPR
MISR2_Mmus_STKR2     -----N-R--RTCVF-F-------EAP-GV---RG--STKTLGEMV----DA--GPGPPK
BMPR2_Mmus_STKR2     -----NQE--RLCAF-K-------D-P-YQ---QD----LGIGESR--------ISHENG
BMPR1B_Mmus_STKR1    -----PKI--LRCK-CH------H----HC---PED----------------------SV
BMPR1A_Mmus_STKR1    -----LPF--LKCY-CS------G----HC---PDD----------------------AI
ALK7_Mmus_STKR1      -------G--LKCV-CL------L-----C---D------------------------SS
ALK4_Mmus_STKR1      -----IQA--LLCA-CT------S-----C---L------------------------QT
ALK2_Mmus_STKR1      -----QKL--YMCV-CE------G--L-SC---GN-------------------------
ALK1_Mmus_STKR1      ------KL--VNCT-CE------S--P-HC---KR-------------------------
ACTR2B_Mmus_STKR2    -----AET--RECIY-Y-------N-A-NW---ELER-T---------N----Q----SG
ACTR2_Mmus_STKR2     -----SET--QECLF-F-------N-A-NW---ERDR-T---------N----Q----TG
daf-4_Cele_STKR2     NEEDEVIS--IECVY-Y-------DEM-EC---EKSG-D-----------C--E----IT
daf-1_Cele_STKR1     -----TRL--HLCH-CS------R--EVGC---NART-TGWVPGIEFLNETDRS----FY
BMPR1A_Hsap_STKR1    -----LPF--LKCY-CS------G----HC---PDD----------------------AI
BMPR1B_Hsap_STKR1    -----PKV--LRCK-CH------H----HC---PED----------------------SV
BMPR2_Hsap_STKR2     -----NQE--RLCAF-K-------D-P-YQ---QD----LGIGESR--------ISHENG
ALK7_Hsap_STKR1      -------G--LKCV-CL------L-----C---D------------------------SS
ALK4_Hsap_STKR1      -----VQA--LLCA-CT------S-----C---L------------------------QA
tkv_Dmel_STKR1       -----ARS--LTCY-CD------G----SC---PDN----------------------VS
put_Dmel_STKR2       -----HGI--IECEH-F-------DEK-MC---NTTQ-Q-----------C--E----TR
SAX_Dmel_STKR1       -----HPR--YKCYSCE------P----PC---RDP-----------------Y----EF
wit_Dmel_STKR2       -----NRQ--YSCMS-Y-------QED-DNSFHDDDGDQDSSGELQEQQVESTPIPSEPH
BABO_Dmel_STKR1      -----ENK--IKCH-CD------T-----C---K------------------------ES
TGFBR1_Mmus_STKR1    -----AKA--LQCF-CH------L-----C---T------------------------KD
TGFBR2_Mmus_STKR2    -----AVKLPQLCKFCD------VRLS-TC---DNQK-S-----------C--MS-NCSI
sma-6_Cele_STKR1     -----ILK--NRCY-CN------YDQS-IC----------------------------GN
ALK2_Hsap_STKR1      -----PKL--YMCV-CE------G--L-SC---GN-------------------------
ALK1_Hsap_STKR1      -----GPL--VTCT-CE------S--P-HC---KG-------------------------
ACTR2B_Hsap_STKR2    -----AET--RECIY-Y-------N-A-NW---ELER-T---------N----Q----SG
ACTR2_Hsap_STKR2     -----SET--QECLF-F-------N-A-NW---EKDR-T---------N----Q----TG
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      -----SVT--LQCN-CD------D--Y-SC---EG-------------------------
BMPR1_Spur_STKR1     ------KM--LYCY-CD------E----HC---PEI----------------------TR
TGFbRII_Spur_STKR2   -----------ECLDCS------EVPV-EC---DAE--S-----------C--VPISCTT
ACTR2_Spur_STKR2     -----LGS--THCHL-Y-------SSQ-EC---EKDG-T---------K-C--G----NT
BMPR2_Spur_STKR2     -----YTE--TF------------------------------------------------
AqueK680_Aque_STKR1  -----LPN--NNIY-THPLTSAKT--P-SC---DIY----------------------AF
AqueK681_Aque_STKR1  -----------QCF-ET------Q--D-GC---SL------------------------T
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------YL--LVCY-TD------D--C-PY---DNNL-L-----------C--Y------
AqueK684_Aque_STKR2  -----SDV--LICER-Y-------NC--SF---NDDG-I-----------C--YHG--Y-
AqueK685_Aque_STKR2  -----SNT--LRS-------------------------H-----------S--F----D-
AqueK686_Aque_STKR2  -----QYS--YNY---------------YC---EAPS-H-----------C--T----P-


TGFbR2_Hsap_STKR2    TSICE---K----PQEVCV-AVWRK------------N---D------------------
TGFbR1_Hsap_STKR1    NFTCV---T-----DGLCF-VSVTE------TT---------------------------
MISR2_Hsap_STKR2     AIRCL---Y-----SRCCF-GIWNL------TQD--------------------------
MISR2_Mmus_STKR2     GIRCL---Y-----SHCCF-GIWNL------THG--------------------------
BMPR2_Mmus_STKR2     TILCS---K-----GSTCY-GLWEK------SKG--------------------------
BMPR1B_Mmus_STKR1    NNICS---T-----DGYCF-TMIEE------DDS--------------------------
BMPR1A_Mmus_STKR1    NNTCI---T-----NGHCF-AIIEE------DDQ--------------------------
ALK7_Mmus_STKR1      NFTCQ---T-----EGACW-ASVML------TN---------------------------
ALK4_Mmus_STKR1      NYTCE---T-----DGACM-VSIFN------LD---------------------------
ALK2_Mmus_STKR1      EDHCE---G------QQCF-SSLSI------NDG--------------------------
ALK1_Mmus_STKR1      -PFCQ---G------SWCT-VVLVR------EQG--------------------------
ACTR2B_Mmus_STKR2    LERCE---GEQD-KRLHCY-ASWRN------S---------S------------------
ACTR2_Mmus_STKR2     VEPCY---GDKD-KRRHCF-ATWKN------I---------S------------------
daf-4_Cele_STKR2     KKTCY---SEAHLKAVGCL-AVFGL------PT---QE--INSTEP--------------
daf-1_Cele_STKR1     ENTCY---T-----DGSCY-QSAR------------------------------------
BMPR1A_Hsap_STKR1    NNTCI---T-----NGHCF-AIIEE------DDQ--------------------------
BMPR1B_Hsap_STKR1    NNICS---T-----DGYCF-TMIEE------DDS--------------------------
BMPR2_Hsap_STKR2     TILCS---K-----GSTCY-GLWEK------SKG--------------------------
ALK7_Hsap_STKR1      NFTCQ---T-----EGACW-ASVML------TN---------------------------
ALK4_Hsap_STKR1      NYTCE---T-----DGACM-VSIFN------LD---------------------------
tkv_Dmel_STKR1       NGTCE---T--R-PGGSCF-SAVQQ------LYD--ET---T------------------
put_Dmel_STKR2       IEHCK---MEAD-KFPSCY-VLWSV-------N---ET---T------------------
SAX_Dmel_STKR1       THTCQ---N-----AIQCW-KSRTR------DAD--------------------------
wit_Dmel_STKR2       RRTCP---D----GYTFCF-TIWNQ------TAN--------------------------
BABO_Dmel_STKR1      NNICE---T-----DGFCF-TSVEK------NSD--------------------------
TGFBR1_Mmus_STKR1    NFTCE---T-----DGLCF-VSVTE------TT---------------------------
TGFBR2_Mmus_STKR2    TAICE---K----PHEVCV-AVWRK------------N---D------------------
sma-6_Cele_STKR1     NMTCV---K--Q-DGAACY-HAVEE------VYN--KA---E------------------
ALK2_Hsap_STKR1      EDHCE---G------QQCF-SSLSI------NDG--------------------------
ALK1_Hsap_STKR1      -PTCR---G------AWCT-VVLVR------EEG--------------------------
ACTR2B_Hsap_STKR2    LERCE---GEQD-KRLHCY-ASWRN------S---------S------------------
ACTR2_Hsap_STKR2     VEPCY---GDKD-KRRHCF-ATWKN------I---------S------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      TNRCE---A-----LRKCF-SSITE------VDG--------------------------
BMPR1_Spur_STKR1     NNTCY---P--S-PGGWCF-AQIQA------GED--------------------------
TGFbRII_Spur_STKR2   SVPCV----------GYCLIATFPDMTSSSMTNGSDPS---S------------------
ACTR2_Spur_STKR2     TEECD---NKEA-EIPSCY-VLWKN------ET---SS---G------------------
BMPR2_Spur_STKR2     ----------------------INI------SRL--------------------------
AqueK680_Aque_STKR1  LHTCI---S-----AIERW-TSRGR------SAD--------------------------
AqueK681_Aque_STKR1  AGVCN---A------STCY-MRILA------KAN--PR---N------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  -KTCT---P----SSNSCV-RIAAI------DRS---N-FPP------------------
AqueK684_Aque_STKR2  -EVCPETFSSNP-DDHSCI-ATYHK------NP---TTNLIELMYKGCRHNRLPNPLTLQ
AqueK685_Aque_STKR2  -ES-T---GTI------------------------------RSV-TGFTTS---------
AqueK686_Aque_STKR2  -QNVP---GSNR-DGYYCY-ASLFI------RN---LN---STDFDGHWFS---------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ------------------------------------------------------------
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     ------------------------------------------------------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ------------------------------------------------------------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ------------------------------------------------------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     ------------------------------------------------------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  ACSNSTSMCHIDNPLVSDQDSAVYYCCCGESLCNQNITFTHPTQVSTYDIDECAINNGGC
AqueK685_Aque_STKR2  ------------------------------------------------------------
AqueK686_Aque_STKR2  ------------------------------------------------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ------------------------------------------------------------
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     -----------------------------------------------YLKV---------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ------------------------------------------------------------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ------------------------------------------------------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     ------------------------------------------------------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  SETCINTPGNYSCECNAGRYLSPHSGRCEDNDGIICLYRNCTLDGSCHTNTTEHCASSHL
AqueK685_Aque_STKR2  -----------------------------------------------LTSI---------
AqueK686_Aque_STKR2  -----------------------------------------------FFQV---------


TGFbR2_Hsap_STKR2    ----------------------EN---IT-LETVCHDPKL-PYHDFILEDAASPKCIMK-
TGFbR1_Hsap_STKR1    ----------------------DK----VIHNSMCIAEID-L-----IPRDRPFVCAPS-
MISR2_Hsap_STKR2     -----------------------R---AQVEMQGCRDSD--------EPGCESLHCDPS-
MISR2_Mmus_STKR2     -----------------------R---AQVEMQGCRDSD--------EPGCESLHCDPV-
BMPR2_Mmus_STKR2     -----------------------D---INLVKQGCWSHIGD------PQECHYEECVVT-
BMPR1B_Mmus_STKR1    ----------------------GM----PVVTSGCLGLE-----------GSDFQCRDT-
BMPR1A_Mmus_STKR1    ----------------------GE----TTLTSGCMKYE-----------GSDFQCKDS-
ALK7_Mmus_STKR1      ----------------------GK----EQVIKSCVSLPE-L--------NAQVFCHSS-
ALK4_Mmus_STKR1      ----------------------GV----EHHVRTCIPKVE-L-----VPAGKPFYCLSS-
ALK2_Mmus_STKR1      -----------------------F----HVYQKGCFQVYE----------QGKMTCKT--
ALK1_Mmus_STKR1      ----------------------RH----PQVYRGCGSLN-------------QELCLG--
ACTR2B_Mmus_STKR2    ----------------------GT---IELVKKGCWLDD--------FNCYDRQECVAT-
ACTR2_Mmus_STKR2     ----------------------GS---IEIVKQGCWLDD--------INCYDRTDCIEK-
daf-4_Cele_STKR2     ----------------------DK---PQYKSLGCMPYQH-ADS---MNCENESSCRQG-
daf-1_Cele_STKR1     -------------------------PSPEISHFGCMDEKS-VTDETEFHDTAAKVCTNN-
BMPR1A_Hsap_STKR1    ----------------------GE----TTLASGCMKYE-----------GSDFQCKDS-
BMPR1B_Hsap_STKR1    ----------------------GL----PVVTSGCLGLE-----------GSDFQCRDT-
BMPR2_Hsap_STKR2     -----------------------D---INLVKQGCWSHIGD------PQECHYEECVVT-
ALK7_Hsap_STKR1      ----------------------GK----EQVIKSCVSLPE-L--------NAQVFCHSS-
ALK4_Hsap_STKR1      ----------------------GM----EHHVRTCIPKVE-L-----VPAGKPFYCLSS-
tkv_Dmel_STKR1       ----------------------GMY--EEERTYGCMPPED-N--------GGFLMCKVA-
put_Dmel_STKR2       ----------------------GI---LRIKMKGCFTDM--------HEC-NQTECVTS-
SAX_Dmel_STKR1       ----------------------GQ----VQESRGCSTSPD----------QLPMICSQNS
wit_Dmel_STKR2       -----------------------G---ARVVKQGCWKDNTDR-----TSICSQSECTSS-
BABO_Dmel_STKR1      ----------------------GS----IIFSYSCMVVKY-N-----MQRSKPFECLTS-
TGFBR1_Mmus_STKR1    ----------------------DK----VIHNSMCIAEID-L-----IPRDRPFVCAPS-
TGFBR2_Mmus_STKR2    ----------------------KN---IT-LETVCHDPKL-TYHGFTLEDAASPKCVMK-
sma-6_Cele_STKR1     ----------------------KR--METLHKWGCATLER-G------SGASHLTCNSW-
ALK2_Hsap_STKR1      -----------------------F----HVYQKGCFQVYE----------QGKMTCKT--
ALK1_Hsap_STKR1      ----------------------RH----PQEHRGCGNLH-------------RELCRG--
ACTR2B_Hsap_STKR2    ----------------------GT---IELVKKGCWLDD--------FNCYDRQECVAT-
ACTR2_Hsap_STKR2     ----------------------GS---IEIVKQGCWLDD--------INCYDRTDCVEK-
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      -----------------------I----IMKRMGCVNTEE----------QFNMFCKM--
BMPR1_Spur_STKR1     ----------------------GVEHETPIRSYGCLAPEE-D--------GGLMQCKGQ-
TGFbRII_Spur_STKR2   ----------------------QN---IN-GMFACINETN-------PEIGGKKHCQAH-
ACTR2_Spur_STKR2     ----------------------GG---VDVMMRGCWQNQ--------GDCLDMDYCMSS-
BMPR2_Spur_STKR2     -----------------------H---QSLYIQGCWGNEAK------SLNCNQENCTAH-
AqueK680_Aque_STKR1  ----------------------GY----SRRGRGCSTCKL-T-----VS--WSQQNKES-
AqueK681_Aque_STKR1  -----------------------ISEHQFSYIYGCLPEEE-GGNGPS---VIASLCSGP-
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ----------------------AR---IIFQEFGCSSLRC-N--------TRDLLCSP--
AqueK684_Aque_STKR2  ISDDLRTETHLHYCVALFHFINGT---FYPNTQSCFAGS-----HSS--C-QNTNCTLT-
AqueK685_Aque_STKR2  -----------------------------------E-HS-----SSR-----------I-
AqueK686_Aque_STKR2  --------------------------------ESCEEAA-----GSE----LTDDCLSI-


TGFbR2_Hsap_STKR2    ------EK------KKPGETFFMCSC-SSDECND--------------------------
TGFbR1_Hsap_STKR1    ------SKT--------GSVTTTYCC-NQDHCNK--------------------------
MISR2_Hsap_STKR2     ------PRAH----PSPGSTLFTCSC-GTDFCNA--------------------------
MISR2_Mmus_STKR2     ------PRAH----PNPSSTLFTCSC-GTDFCNA--------------------------
BMPR2_Mmus_STKR2     ------TTPP----SIQNGTYRFCCC-STDLCNV--------------------------
BMPR1B_Mmus_STKR1    ------PIP--------HQRRSIECCTERNECNK--------------------------
BMPR1A_Mmus_STKR1    ------PKA--------QLRRTIECC-RTNLCNQ--------------------------
ALK7_Mmus_STKR1      ------N-----------NVTKTECC-FTDFCNN--------------------------
ALK4_Mmus_STKR1      ------E-----------DLRNTHCC-YIDFCNK--------------------------
ALK2_Mmus_STKR1      -------P-------P-SPGQAVECC-QGDWCNR--------------------------
ALK1_Mmus_STKR1      -------R-------P-TEFLNHHCC-YRSFCNH--------------------------
ACTR2B_Mmus_STKR2    ------EE---------NPQVYFCCC-EGNFCNE--------------------------
ACTR2_Mmus_STKR2     ------KD---------SPEVYFCCC-EGNMCNE--------------------------
daf-4_Cele_STKR2     ------RS--------FRGGIGMCCC-STNNCNM--------------------------
daf-1_Cele_STKR1     ------TK------D-PHATVWICCD-KGNFCAN--------------------------
BMPR1A_Hsap_STKR1    ------PKA--------QLRRTIECC-RTNLCNQ--------------------------
BMPR1B_Hsap_STKR1    ------PIP--------HQRRSIECCTERNECNK--------------------------
BMPR2_Hsap_STKR2     ------TTPP----SIQNGTYRFCCC-STDLCNV--------------------------
ALK7_Hsap_STKR1      ------N-----------NVTKTECC-FTDFCNN--------------------------
ALK4_Hsap_STKR1      ------E-----------DLRNTHCC-YTDYCNR--------------------------
tkv_Dmel_STKR1       ------AVP-----H--LHGKNIVCCDKEDFCNR--------------------------
put_Dmel_STKR2       ------AE-------PRQGNIHFCCC-KGSRCNS--------------------------
SAX_Dmel_STKR1       LKINGPSKR-----NT-GKFVNVVCC-AGDYCNE--------------------------
wit_Dmel_STKR2       --------AP----TSKTSSLYYCCC-SGGVCNA--------------------------
BABO_Dmel_STKR1      ------NER--------FDTYRIDCC-KSDFCNK--------------------------
TGFBR1_Mmus_STKR1    ------SKT--------GAVTTTYCC-NQDHCNK--------------------------
TGFBR2_Mmus_STKR2    ------EK------KRAGETFFMCAC-NMEECND--------------------------
sma-6_Cele_STKR1     ------RAA-----H--HSPKSIGCCYEGNYCNK--------------------------
ALK2_Hsap_STKR1      -------P-------P-SPGQAVECC-QGDWCNR--------------------------
ALK1_Hsap_STKR1      -------R-------P-TEFVNHYCC-DSHLCNH--------------------------
ACTR2B_Hsap_STKR2    ------EE---------NPQVYFCCC-EGNFCNE--------------------------
ACTR2_Hsap_STKR2     ------KD---------SPEVYFCCC-EGNMCNE--------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      -------H-------P-YPDISVLCC-NRSFCNN--------------------------
BMPR1_Spur_STKR1     ------LSN-----H--RISRTVYCCNDEPNCNL--------------------------
TGFbRII_Spur_STKR2   ------PDDY----SYAAEGSYSCSC-ASDGCNK--------------------------
ACTR2_Spur_STKR2     ------SP--------ADQNLFFCCC-VGNLCNM--------------------------
BMPR2_Spur_STKR2     ------SKPSEYLVRTKNQTSRICCC-AGDYCNR--------------------------
AqueK680_Aque_STKR1  ------PSE-----QPVNKVMHFFCC-DDDYCNQ--------------------------
AqueK681_Aque_STKR1  ------ASW-----D-RELLISYTCC-TSDHCNK--------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  -------N-------I-TDLTQHCCC-TGDRCNNPGGRADALAELMKPKFSYHLSPPNEP
AqueK684_Aque_STKR2  ---NIT-RL-----S-HNNDVYSCCC-YGDLCNE--------------------------
AqueK685_Aque_STKR2  ---ISS-IP-----Q-ST-NSLTSVS-TRSSTES--------------------------
AqueK686_Aque_STKR2  ---TKR-VS-----S-LEGTNIFCRC-TEDNCQD--------------------------


TGFbR2_Hsap_STKR2    ---------------------------------------------NIIFSE---------
TGFbR1_Hsap_STKR1    ---------------------------------------------IEL------------
MISR2_Hsap_STKR2     ---------------------------------------------NYSH-L---------
MISR2_Mmus_STKR2     ---------------------------------------------NYSH-L---------
BMPR2_Mmus_STKR2     ---------------------------------------------NFTENF---------
BMPR1B_Mmus_STKR1    ---------------------------------------------DLHPTL---------
BMPR1A_Mmus_STKR1    ---------------------------------------------YLQPTL---------
ALK7_Mmus_STKR1      ---------------------------------------------ITL-HL---------
ALK4_Mmus_STKR1      ---------------------------------------------IDL-RV---------
ALK2_Mmus_STKR1      ---------------------------------------------NITAQ----------
ALK1_Mmus_STKR1      ---------------------------------------------NVSLM----------
ACTR2B_Mmus_STKR2    ---------------------------------------------RFT-HL---------
ACTR2_Mmus_STKR2     ---------------------------------------------KFS-YF---------
daf-4_Cele_STKR2     ---------------------------------------------PDLIEM---------
daf-1_Cele_STKR1     ---------------------------------------------ETIIHL---------
BMPR1A_Hsap_STKR1    ---------------------------------------------YLQPTL---------
BMPR1B_Hsap_STKR1    ---------------------------------------------DLHPTL---------
BMPR2_Hsap_STKR2     ---------------------------------------------NFTENF---------
ALK7_Hsap_STKR1      ---------------------------------------------ITL-HL---------
ALK4_Hsap_STKR1      ---------------------------------------------IDL-RV---------
tkv_Dmel_STKR1       ---------------------------------------------DLYPTY---------
put_Dmel_STKR2       ---------------------------------------------NQK-YI---------
SAX_Dmel_STKR1       ---------------------------------------------GDFPEL---------
wit_Dmel_STKR2       ---------------------------------------------QYSV-VE--------
BABO_Dmel_STKR1      ---------------------------------------------NEI-MK---------
TGFBR1_Mmus_STKR1    ---------------------------------------------IEL------------
TGFBR2_Mmus_STKR2    ---------------------------------------------YIIFSE---------
sma-6_Cele_STKR1     ---------------------------------------------NLIPPA---------
ALK2_Hsap_STKR1      ---------------------------------------------NITAQ----------
ALK1_Hsap_STKR1      ---------------------------------------------NVSLV----------
ACTR2B_Hsap_STKR2    ---------------------------------------------RFT-HL---------
ACTR2_Hsap_STKR2     ---------------------------------------------KFS-YF---------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ---------------------------------------------DLQPTF---------
BMPR1_Spur_STKR1     ---------------------------------------------KLNPTL---------
TGFbRII_Spur_STKR2   ---------------------------------------------VLYTAE---------
ACTR2_Spur_STKR2     ---------------------------------------------NFS-FL---------
BMPR2_Spur_STKR2     ---------------------------------------------NVSDAYV--------
AqueK680_Aque_STKR1  ---------------------------------------------DIMHSI---------
AqueK681_Aque_STKR1  ---------------------------------------------NIEPRHDIESLLINR
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  VPSTEPGCSVANTSDITPDCIIDVPFIGALKNEYTCYCNESLCNINESITH---------
AqueK684_Aque_STKR2  ---------------------------------------------RGLIF----------
AqueK685_Aque_STKR2  --------------------------------------------------V---------
AqueK686_Aque_STKR2  ---------------------------------------------IFNVTII--------


TGFbR2_Hsap_STKR2    -------------------EY---------------------------------------
TGFbR1_Hsap_STKR1    -------------------PT---------------------TVK---------------
MISR2_Hsap_STKR2     -------------------PP---------------------PGS---------------
MISR2_Mmus_STKR2     -------------------PP---------------------SGN---------------
BMPR2_Mmus_STKR2     -------------------PP---------------------PDT---------------
BMPR1B_Mmus_STKR1    -------------------PP---------------------LKD---------------
BMPR1A_Mmus_STKR1    -------------------PP---------------------VVI---------------
ALK7_Mmus_STKR1      -------------------PT---------------------ASP---------------
ALK4_Mmus_STKR1      -------------------PS---------------------GHL---------------
ALK2_Mmus_STKR1      -------------------LP---------------------TKG---------------
ALK1_Mmus_STKR1      -------------------LE---------------------ATQ---------------
ACTR2B_Mmus_STKR2    -------------------PE---------------------PGG---------------
ACTR2_Mmus_STKR2     -------------------PE---------------------MEV---------------
daf-4_Cele_STKR2     -------------------VN---------------------PSL---------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    -------------------PP---------------------VVI---------------
BMPR1B_Hsap_STKR1    -------------------PP---------------------LKN---------------
BMPR2_Hsap_STKR2     -------------------PP---------------------PDT---------------
ALK7_Hsap_STKR1      -------------------PT---------------------ASP---------------
ALK4_Hsap_STKR1      -------------------PS---------------------GHL---------------
tkv_Dmel_STKR1       -------------------TP---------------------KLT---------------
put_Dmel_STKR2       -------------------KS---------------------TT----------------
SAX_Dmel_STKR1       -------------------LP---------------------FDS---------------
wit_Dmel_STKR2       -------------------PA---------------------PLE---------------
BABO_Dmel_STKR1      -------------------RI---------------------FE----------------
TGFBR1_Mmus_STKR1    -------------------PT---------------------TGP---------------
TGFBR2_Mmus_STKR2    -------------------EY---------------------------------------
sma-6_Cele_STKR1     -------------------YVHHHKEKALQ----------EKTDN---------------
ALK2_Hsap_STKR1      -------------------LP---------------------TKG---------------
ALK1_Hsap_STKR1      -------------------LE---------------------ATQ---------------
ACTR2B_Hsap_STKR2    -------------------PE---------------------AGG---------------
ACTR2_Hsap_STKR2     -------------------PE---------------------MEV---------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      -------------------LP---------------------TTT---------------
BMPR1_Spur_STKR1     -------------------PP---------------------TTT---------------
TGFbRII_Spur_STKR2   -------------------ATI--------------------PEE---------------
ACTR2_Spur_STKR2     -------------------PT---------------------PE----------------
BMPR2_Spur_STKR2     -------------------PL---------------------PST---------------
AqueK680_Aque_STKR1  -------------------LE---------------------SVS---------------
AqueK681_Aque_STKR1  YNNDSNDQESSSVFVSSSVPS---------------------SSSVPILPSVPILLSVPI
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  -------------------PT---------------------RLS---------------
AqueK684_Aque_STKR2  -------------------PDFN-----------------A-TSP--I-P----------
AqueK685_Aque_STKR2  -----------------LVP----------------------------------------
AqueK686_Aque_STKR2  -----------------IDPPND------VSSSTLINGVIT-SSP--S-P----------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ------------------------------------------------------------
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     ------------------------------------------------------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ------------------------------------------------------------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ------------------------------------------------------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     ------------------------------------------------------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  SPSVPISPSVPISF----------------SSSYQYLYDLTSLPTKDTSTFNNPSIIIYF
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  -MSS--------------------------------------------------------
AqueK685_Aque_STKR2  ------------------------------------------------------------
AqueK686_Aque_STKR2  -PSVY--SSVPLSLSLSSSTIDLTTSSVSFS-----------------------------


TGFbR2_Hsap_STKR2    ------------------------------------NTS---------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     -------------------------------------PGT--------------------
MISR2_Mmus_STKR2     -------------------------------------QGA--------------------
BMPR2_Mmus_STKR2     ------------------------------------TPLS--------------------
BMPR1B_Mmus_STKR1    ------------------------------------RD-F--------------------
BMPR1A_Mmus_STKR1    ------------------------------------GP-F--------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------KE-P--------------------
ALK2_Mmus_STKR1      ------------------------------------KS-F--------------------
ALK1_Mmus_STKR1      ------------------------------------TP-S--------------------
ACTR2B_Mmus_STKR2    ------------------------------------PE-V--------------------
ACTR2_Mmus_STKR2     ------------------------------------TQ-P--------------------
daf-4_Cele_STKR2     ------------------------------------KK-D--------------------
daf-1_Cele_STKR1     -------------------------------------A-P--------------------
BMPR1A_Hsap_STKR1    ------------------------------------GP-F--------------------
BMPR1B_Hsap_STKR1    ------------------------------------RD-F--------------------
BMPR2_Hsap_STKR2     ------------------------------------TPLS--------------------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------KE-P--------------------
tkv_Dmel_STKR1       ------------------------------------TP-A--------------------
put_Dmel_STKR2       ------------------------------------EA-T--------------------
SAX_Dmel_STKR1       ------------------------------------ND-V--------------------
wit_Dmel_STKR2       ------------------------------------LGSN--------------------
BABO_Dmel_STKR1      -------------------------------------T-D--------------------
TGFBR1_Mmus_STKR1    ----------------F-------------------SE-K--------------------
TGFBR2_Mmus_STKR2    ------------------------------------TTS---------------------
sma-6_Cele_STKR1     ------------------------------------PE-D--------------------
ALK2_Hsap_STKR1      ------------------------------------KS-F--------------------
ALK1_Hsap_STKR1      ------------------------------------PP-S--------------------
ACTR2B_Hsap_STKR2    ------------------------------------PE-V--------------------
ACTR2_Hsap_STKR2     ------------------------------------TQ-P--------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------PR-I--------------------
BMPR1_Spur_STKR1     ------------------------------------ST-T--------------------
TGFbRII_Spur_STKR2   ------------------------------------PTVP--------------------
ACTR2_Spur_STKR2     ------------------------------------PT-P--------------------
BMPR2_Spur_STKR2     ------------------------------------KPTV--------------------
AqueK680_Aque_STKR1  ------------------------------------AT----------------------
AqueK681_Aque_STKR1  SEPTNDPHLYDLTSLPTKDTSTFNNSSIIIY--F--SE-P--------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------SYGFKECLSYNCEYNCNIVNNTNI
AqueK684_Aque_STKR2  ------TSLMA-------SSDS---ITIFLS---SSPY-V--------------------
AqueK685_Aque_STKR2  -------------------------------------S-S--------------------
AqueK686_Aque_STKR2  -I-NTSPTLIT------VTNTH---TTGILTTSSVVPS-S--------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ------------------------------------------------------------
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     ------------------------------------------------------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ------------------------------------------------------------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ------------------------------------------------------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     ------------------------------------------------------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  NCSCPAGFIAIGFTRCRDVNECLVSNGGCQQTCVNTIGSYYCECFDGYFFDSRTLSCLSK
AqueK684_Aque_STKR2  ------------------------------------------------------------
AqueK685_Aque_STKR2  ------------------------------------------------------------
AqueK686_Aque_STKR2  ------------------------------------------------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    -------------------------------------------------------S----
MISR2_Hsap_STKR2     ------------------------------------------------------PG----
MISR2_Mmus_STKR2     ------------------------------------------------------PG----
BMPR2_Mmus_STKR2     ------------------------------------------------------P-----
BMPR1B_Mmus_STKR1    ------------------------------------------------------V-----
BMPR1A_Mmus_STKR1    ------------------------------------------------------F-----
ALK7_Mmus_STKR1      -------------------------------------------------------N----
ALK4_Mmus_STKR1      -------------------------------------------------------A----
ALK2_Mmus_STKR1      ------------------------------------------------------PG----
ALK1_Mmus_STKR1      -------------------------------------------------------E----
ACTR2B_Mmus_STKR2    ------------------------------------------------------TY----
ACTR2_Mmus_STKR2     ------------------------------------------------------TS----
daf-4_Cele_STKR2     ------------------------------------------------------SDNSAL
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------F-----
BMPR1B_Hsap_STKR1    ------------------------------------------------------V-----
BMPR2_Hsap_STKR2     ------------------------------------------------------P-----
ALK7_Hsap_STKR1      -------------------------------------------------------N----
ALK4_Hsap_STKR1      -------------------------------------------------------E----
tkv_Dmel_STKR1       ------------------------------------------------------PD----
put_Dmel_STKR2       ------------------------------------------------------TQ----
SAX_Dmel_STKR1       ------------------------------------------------------TV----
wit_Dmel_STKR2       ------------------------------------------------------EG----
BABO_Dmel_STKR1      -------------------------------------------------------Y----
TGFBR1_Mmus_STKR1    -------------------------------------------------------Q----
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------YD----
ALK2_Hsap_STKR1      ------------------------------------------------------PG----
ALK1_Hsap_STKR1      -------------------------------------------------------E----
ACTR2B_Hsap_STKR2    ------------------------------------------------------TY----
ACTR2_Hsap_STKR2     ------------------------------------------------------TS----
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------TE----
TGFbRII_Spur_STKR2   ------------------------------------------------------PSS---
ACTR2_Spur_STKR2     ------------------------------------------------------TV----
BMPR2_Spur_STKR2     ------------------------------------------------------TQ----
AqueK680_Aque_STKR1  ------------------------------------------------------PT----
AqueK681_Aque_STKR1  ------------------------------------------------------TN----
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  FANFYCSHYSDDDIRLTEITENTKIGSLDCTPVQSCFAQLMYSHHHWYLNAMTCGQ----
AqueK684_Aque_STKR2  ------------------------------------------------------SA----
AqueK685_Aque_STKR2  ------------------------------------------------------TV----
AqueK686_Aque_STKR2  ------------------------------------------------------TG----


TGFbR2_Hsap_STKR2    ----NP--D-----------------------------------------LLLVIFQVTG
TGFbR1_Hsap_STKR1    ----SP--G------------------------------------LGP-VE-LAAV-I--
MISR2_Hsap_STKR2     ----SQ--GP-Q----------A----------------------APG-ESIWMAL-V--
MISR2_Mmus_STKR2     ----PQ--EP-Q----------A----------------------TPG-GPVWMAL-L--
BMPR2_Mmus_STKR2     -----------P----------H----------------------SFN-RD-ETII-I--
BMPR1B_Mmus_STKR1    ---------------------------------------------DGP-IHHKALL-I--
BMPR1A_Mmus_STKR1    ---------------------------------------------DGS-IRWLVVL-I--
ALK7_Mmus_STKR1      ----AP--R------------------------------------LGP-TE-LTVV-I--
ALK4_Mmus_STKR1      ----HP--SM-----------------------------------WGP-VE-LVGI-I--
ALK2_Mmus_STKR1      ----TQ--NF-----------------------------------H---LEVGLII-L--
ALK1_Mmus_STKR1      ----EP--EV-----------------------------------D---AHLP-LI-L--
ACTR2B_Mmus_STKR2    ----EP--PP-----------------------------------TAP-TLLTVLA-Y--
ACTR2_Mmus_STKR2     ----NP--VT-----------------------------------PKP-PYYNILL-Y--
daf-4_Cele_STKR2     LWASTP--SN-MDLE-------S---------------------LDKF-PFYWIII-I--
daf-1_Cele_STKR1     ----GP--QQ-----------------------------------S---ST--WLI-L--
BMPR1A_Hsap_STKR1    ---------------------------------------------DGS-IRWLVLL-I--
BMPR1B_Hsap_STKR1    ---------------------------------------------DGP-IHHRALL-I--
BMPR2_Hsap_STKR2     -----------P----------H----------------------SFN-RD-ETII-I--
ALK7_Hsap_STKR1      ----AP--K------------------------------------LGP-ME-LAII-I--
ALK4_Hsap_STKR1      ----HP--SM-----------------------------------WGP-VE-LVGI-I--
tkv_Dmel_STKR1       ----LP--VS-----------------------------------SES-LHTLAVF-G--
put_Dmel_STKR2       ----VP--KE-K----------T---------------------QDGS-NLIYIYI-G--
SAX_Dmel_STKR1       ----IT--AD-----------------------------------T---SSISKML-V--
wit_Dmel_STKR2       ----RTSITNRA----------T----------------------EKQ-HQSFLAS-T--
BABO_Dmel_STKR1      ----VP--HR-----------------------------------LTS-WE-FVAI-I--
TGFBR1_Mmus_STKR1    ----SA--G------------------------------------LGP-VE-LAAV-I--
TGFBR2_Mmus_STKR2    ----SP--D-----------------------------------------LLLVIIQVTG
sma-6_Cele_STKR1     ----SP--LE-----------------------------------NMTRGGKMFIM-V--
ALK2_Hsap_STKR1      ----TQ--NF-----------------------------------H---LEVGLII-L--
ALK1_Hsap_STKR1      ----QP--GT-----------------------------------D---GQLA-LI-L--
ACTR2B_Hsap_STKR2    ----EP--PP-----------------------------------TAP-TLLTVLA-Y--
ACTR2_Hsap_STKR2     ----NP--VT-----------------------------------PKP-PYYNILL-Y--
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ----TE--G---------------------------------------------------
BMPR1_Spur_STKR1     ----LP--GV-E--D-------T---------------------YNTT-VHQIALL-I--
TGFbRII_Spur_STKR2   ----EP--DATP----------TKTKGPPIENTDPNKTEEGRKGQMLD-REILVIV-V--
ACTR2_Spur_STKR2     ----TQ--TT-V--TGSNIDEKK---------------------KKNE-MLTKTIL-Y--
BMPR2_Spur_STKR2     ----YKVISD-Q----------M----------------------NHE-ME-RTIL-I--
AqueK680_Aque_STKR1  ----VS--SN------------------------------------DP-SLYIIIL-V--
AqueK681_Aque_STKR1  ----DP--QQ-----------------------------------I---SD-LNTV-I--
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ----SP--GH-----------------------------------TVT-VGFWSAI----
AqueK684_Aque_STKR2  ---T-Q--TA-S---------------------------------SNRVVYPSVFA-A--
AqueK685_Aque_STKR2  --------TS-T----------A----------------------AVTIGLASGIS-I--
AqueK686_Aque_STKR2  ---VIP--ST-D----------T----------------------MVTIILSSVIA-F--


TGFbR2_Hsap_STKR2    ISLLPPLGVAISVII-I--FYCYRVNRQQKL----S--S-TWE-TGKTR-----------
TGFbR1_Hsap_STKR1    -AG-PVCFVCISLML-MVYIC-HNRTVIHH-----RVP--NEE-DPSLD----R------
MISR2_Hsap_STKR2     -LLGLFLLLLLLLGS-IILALLQRKNY-RV-----RGE--PVP-EPRP------------
MISR2_Mmus_STKR2     -LLGMFLVL--LLSS-IILALLQRKAC-RV-----QGG--SDP-E--P------------
BMPR2_Mmus_STKR2     -ALASVSVLAVLIVA-LCFGYRMLTGD-RK-----QGL-HSMN-MMEA------------
BMPR1B_Mmus_STKR1    -SV-TVCSLLLVLII-L-FCYFRYKRQ-EA-----RPR-YSIG-LE-QD----E------
BMPR1A_Mmus_STKR1    -SM-AVCIVAMIIFS-SCFCYKHYCKSISS-----RGR-YNRD-LE-QD----E------
ALK7_Mmus_STKR1      -TV-PVCLLSIAAML-TIWACQDRQCTYRK-----TKR-HNVE-EALAE----Y------
ALK4_Mmus_STKR1      -AG-PVFLLFLIIII-VFLVINYHQRVYHN-----RQR-LDME-DPSCE-----------
ALK2_Mmus_STKR1      -SV-VFAVCLLACIL-GVALRKFKRRNQER-----LN-PRDVE-YGTIE----G-LIT--
ALK1_Mmus_STKR1      -GP-VLALPVLVALG-ALGLWRVRRRQEKQ-----RD--LHSD-LGESS----L-ILK--
ACTR2B_Mmus_STKR2    -SLLPIGGLSLIVL---LAFWMYRHRKPPYG----HVD---IH-E----VRQCQRWAGR-
ACTR2_Mmus_STKR2     -SLVPLMLIAGIVI---CAFWVYRHHKMAYP----PVL---V------------------
daf-4_Cele_STKR2     -ALSVILCIALLIL--AYVGWKFQQNKKEEI----KKQ-QKIKFD----MEKT-------
daf-1_Cele_STKR1     -TILAL-LTFI-VLL-GIAIFLTRKSWEAKFDWYIRFKP-KPG-DPLRETENNVPMVTMG
BMPR1A_Hsap_STKR1    -SM-AVCIIAMIIFS-SCFCYKHYCKSISS-----RRR-YNRD-LE-QD----E------
BMPR1B_Hsap_STKR1    -SV-TVCSLLLVLII-L-FCYFRYKRQ-ET-----RPR-YSIG-LE-QD----E------
BMPR2_Hsap_STKR2     -ALASVSVLAVLIVA-LCFGYRMLTGD-RK-----QGL-HSMN-MMEA------------
ALK7_Hsap_STKR1      -TV-PVCLLSIAAML-TVWACQGRQCSYRK-----KKR-PNVE-EPLSE----C------
ALK4_Hsap_STKR1      -AG-PVFLLFLIIII-VFLVINYHQRVYHN-----RQR-LDME-DPSCE-----------
tkv_Dmel_STKR1       -SI-IISLSVFMLIV-ASLCFTYKRRE-KL-----RKQ-PRLI-NSMCN-----------
put_Dmel_STKR2       -TSV-FSVLMVIVG---MGLLLYRRRKQAHF----N-E---I------------------
SAX_Dmel_STKR1       -AV-LGPFLVIALLG-AVTIFFIRRSHRKR-----LAASRTKQ-DPEAYLVNDE-LLR--
wit_Dmel_STKR2       -MLGLAGGLTALTIG-IFLAVQYCRTA-KE-----KPE--PEE-SPLA------------
BABO_Dmel_STKR1      -LG-ATLFICFTGTS-TWYYC-QRRKRMAS-----GRT-FAKE-DSAYD-----------
TGFBR1_Mmus_STKR1    -AG-PVCFVCIALML-MVYIC-HNRTVIHH-----RVP--NEE-DPSLD----R------
TGFBR2_Mmus_STKR2    VSLLPPLGIAIAVII-I--FYCYRVHRQQKL----S--P-SWE-SSKPR-----------
sma-6_Cele_STKR1     -F-ATVMSV-FAVIG-CIYLCITRAEEKSKA----RARAKTVS-LK-TE----S------
ALK2_Hsap_STKR1      -SV-VFAVCLLACLL-GVALRKFKRRNQER-----LN-PRDVE-YGTIE----G-LIT--
ALK1_Hsap_STKR1      -GP-VLALLALVALG-VLGLWHVRRRQEKQ-----RG--LHSE-LGESS----L-ILK--
ACTR2B_Hsap_STKR2    -SLLPIGGLSLIVL---LAFWMYRHRKPPYG----HVD---IH-----------------
ACTR2_Hsap_STKR2     -SLVPLMLIAGIVI---CAFWVYRHHKMAYP----PVL---V------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     -SV-TFCAAAFIIAL-TFF-YLRYKKR-EV-----RRR-YDFE-VAQQD----D------
TGFbRII_Spur_STKR2   CSVVPAVLLTIVIAV-A--GYIHFTRYRQPM----N--D-ELN-TQ-TQ-----------
ACTR2_Spur_STKR2     -SIVPIVAIALVII---MLYWMCRRHRYH-S----LIA---I------------------
BMPR2_Spur_STKR2     -AVIPIFCVSVAIAI-MYFIFRMRLRS-TK-----AQM-SQLP-MIEA------------
AqueK680_Aque_STKR1  -TIISSCIILIILFF-ALFIFCKRKRDRRLP----RQRTNDPD-VHLTE----P-HHS--
AqueK681_Aque_STKR1  -PVIVVLLVIAAVII-LLAIFIHRRSTKSNN----RGKQ-RG-------NEGST-K----
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  -GSLSMIIIGIVCALWITIAFKWKTTRSKY-----RKA-IDYS-LSLD------------
AqueK684_Aque_STKR2  -LLLIMVLILCSIS--IILCR-VR-VAFRK-----RLDMSNYQ-LS--------------
AqueK685_Aque_STKR2  -LALMIALIAVVMM--LILAYSWRKHSPKF-----HRCSHQIQ-FSS-------------
AqueK686_Aque_STKR2  -LAITLAIIGLLIAC-TLVCYC-RKYSSNS-----RRHSHQIQ-FP--------------


TGFbR2_Hsap_STKR2    -----------------------------KLMEFSEHCAII-LEDD--RSD----I-SS-
TGFbR1_Hsap_STKR1    -----------------------------PFISEGTTLKDL-IYDM--TTS----G-SG-
MISR2_Hsap_STKR2     ----------------------------------------------------------D-
MISR2_Mmus_STKR2     ----------------------------------------------------------G-
BMPR2_Mmus_STKR2     ----------------------------------------------------------A-
BMPR1B_Mmus_STKR1    -----------------------------TYIPPGESLRDL-IEQS--QSS----G-SG-
BMPR1A_Mmus_STKR1    -----------------------------AFIPVGESLKDL-IDQS--QSS----G-SG-
ALK7_Mmus_STKR1      -----------------------------SLVNAGKTLKDL-IYDA--TAS----G-SG-
ALK4_Mmus_STKR1      -----------------------------MCLSKDKTLQDL-VYDL--STS----G-SG-
ALK2_Mmus_STKR1      ------------------------------TNVGDSTLAEL-LDHS--CTS----G-SG-
ALK1_Mmus_STKR1      -----------------------------ASEQADSMLGDF-LDSD--CTT----G-SG-
ACTR2B_Mmus_STKR2    ----------------------------------RDGCADS-FKPLPFQDP----G-PP-
ACTR2_Mmus_STKR2     ----------------------------------------------PTQDP----G-PP-
daf-4_Cele_STKR2     ----------------------------------------------DALEA----GNVPL
daf-1_Cele_STKR1     DGAGSSVPEVAPIEQQGSTMSTSAGNSFPPGIMP-NNMKDM-LDVL-EETS----G-SG-
BMPR1A_Hsap_STKR1    -----------------------------AFIPVGESLKDL-IDQS--QSS----G-SG-
BMPR1B_Hsap_STKR1    -----------------------------TYIPPGESLRDL-IEQS--QSS----G-SG-
BMPR2_Hsap_STKR2     ----------------------------------------------------------A-
ALK7_Hsap_STKR1      -----------------------------NLVNAGKTLKDL-IYDV--TAS----G-SG-
ALK4_Hsap_STKR1      -----------------------------MCLSKDKTLQDL-VYDL--STS----G-SG-
tkv_Dmel_STKR1       --------------------------------SQLSPLSQL-VE----QSS----G-SG-
put_Dmel_STKR2       ----------------------------------------------PTHEA----E-IT-
SAX_Dmel_STKR1       -----------------------------ATSAGDSTLREY-LQHS--VTS----G-SG-
wit_Dmel_STKR2       ----------------------------------------------------------P-
BABO_Dmel_STKR1      -----------------------------PILNGNTTIHDI-IEM---TTS----G-SGS
TGFBR1_Mmus_STKR1    -----------------------------PFISEGTTLKDL-IYDM--TTS----G-SG-
TGFBR2_Mmus_STKR2    -----------------------------KLMDFSDNCAII-LEDD--RSD----I-SS-
sma-6_Cele_STKR1     -----------------------------TYMES--------KSML--EDS----G-SG-
ALK2_Hsap_STKR1      ------------------------------TNVGDSTLADL-LDHS--CTS----G-SG-
ALK1_Hsap_STKR1      -----------------------------ASEQGDSMLGDL-LDSD--CTT----G-SG-
ACTR2B_Hsap_STKR2    ------------------------------------------------EDP----G-PP-
ACTR2_Hsap_STKR2     ----------------------------------------------PTQDP----G-PP-
TGFbR1_Spur_STKR1    -----------------------------------------------------------I
ALK2_Spur_STKR1      -----------------------------------LFCFDL-FDHS--NTS----G-SG-
BMPR1_Spur_STKR1     -----------------------------SFIGPGETLSEL-LEKS--SAS----G-SG-
TGFbRII_Spur_STKR2   ------------------------------TSNTESTSIDMTTDES--ETKRLGEY-SP-
ACTR2_Spur_STKR2     ----------------------------------------------PTTE--------P-
BMPR2_Spur_STKR2     ----------------------------------------------------------P-
AqueK680_Aque_STKR1  -------------------------------NGNGNDLTSF-LQMS--FTS----G-SG-
AqueK681_Aque_STKR1  -------------------------------VRP-EDVERE-MEIL--STS----G-SG-
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  -------------------------------------------------------N-SN-
AqueK684_Aque_STKR2  ------------------------------------------------------------
AqueK685_Aque_STKR2  ------------------------------------------------------------
AqueK686_Aque_STKR2  ------------------------------------------------------------


TGFbR2_Hsap_STKR2    ----TCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPY--EE
TGFbR1_Hsap_STKR1    ----SGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRG------EEVAVKIFSS--RE
MISR2_Hsap_STKR2     ----SGRDWSVELQELPELCFSQVIREGGHAVVWAGQLQG------KLVAIKAFPP--RS
MISR2_Mmus_STKR2     ----SGGDCSEELPELAELRFSQVIQEGGHAVVWAGRLQG------EMVAIKAFPP--RA
BMPR2_Mmus_STKR2     ----A----AEPSLDLDNLKLLELIGRGRYGAVYKGSLDE------RPVAVKVFSF--AN
BMPR1B_Mmus_STKR1    ----SGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRG------EKVAVKVFFT--TE
BMPR1A_Mmus_STKR1    ----SGLPLLVQRTIAKQIQMVRQVGKGRYGEVWMGKWRG------EKVAVKVFFT--TE
ALK7_Mmus_STKR1      ----SGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCG------EDVAVKIFSS--RD
ALK4_Mmus_STKR1      ----SGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRG------GDVAVKIFSS--RE
ALK2_Mmus_STKR1      ----SGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQG------ENVAVKIFSS--RD
ALK1_Mmus_STKR1      ----SGLPFLVQRTVARQVALVECVGKGRYGEVWRGSWHG------ESVAVKIFSS--RD
ACTR2B_Mmus_STKR2    --------PPSPLVGLKPLQLLEIKARGRFGCVWKAQLMN------DFVAVKIFPL--QD
ACTR2_Mmus_STKR2     --------PPSPLLGLKPLQLLEVKARGRFGCVWKAQLLN------EYVAVKIFPI--QD
daf-4_Cele_STKR2     VEPEEEMIEMVETPKELPITDFQLISKGRFGKVFKAQYTPDSG-EKRLVAVKKLNE--FQ
daf-1_Cele_STKR1     ----MGPTTLHKLTIGGQIRLTGRVGSGRFGNVSRGDYRG------EAVAVKVFNA--LD
BMPR1A_Hsap_STKR1    ----SGLPLLVQRTIAKQIQMVRQVGKGRYGEVWMGKWRG------EKVAVKVFFT--TE
BMPR1B_Hsap_STKR1    ----SGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRG------EKVAVKVFFT--TE
BMPR2_Hsap_STKR2     ----A----SEPSLDLDNLKLLELIGRGRYGAVYKGSLDE------RPVAVKVFSF--AN
ALK7_Hsap_STKR1      ----SGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCG------EDVAVKIFSS--RD
ALK4_Hsap_STKR1      ----SGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRG------GDVAVKIFSS--RE
tkv_Dmel_STKR1       ----SGLPLLVQRTIAKQIQMVRLVGKGRYGEVWLAKWRD------ERVAVKTFFT--TE
put_Dmel_STKR2       --------NSSPLLSNRPIQLLEQKASGRFGDVWQAKLNN------QDVAVKIFRM--QE
SAX_Dmel_STKR1       ----SGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHG------ESIAVKIFFS--RD
wit_Dmel_STKR2       ----SGPGYSSNLRNVDNMNLIGMLGSGKYGTVMKGLLHD------QEVAVKIYPE--EH
BABO_Dmel_STKR1      ----AGLPLLVQRSIARQVQLCHVIGKGRFGEVWRGRWRG------ENVAVKIFSS--RE
TGFBR1_Mmus_STKR1    ----SGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRG------EEVAVKIFSS--RE
TGFBR2_Mmus_STKR2    ----TCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPY--EE
sma-6_Cele_STKR1     ----SGQAALIQRTVRQDLTIIKTIGQGRYGEVRKALYRG------SYVAVKTFYT--TD
ALK2_Hsap_STKR1      ----SGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQG------ENVAVKIFSS--RD
ALK1_Hsap_STKR1      ----SGLPFLVQRTVARQVALVECVGKGRYGEVWRGLWHG------ESVAVKIFSS--RD
ACTR2B_Hsap_STKR2    --------PPSPLVGLKPLQLLEIKARGRFGCVWKAQLMN------DFVAVKIFPL--QD
ACTR2_Hsap_STKR2     --------PPSPLLGLKPLQLLEVKARGRFGCVWKAQLLN------EYVAVKIFPI--QD
TGFbR1_Spur_STKR1    ----QGLPLLVQRTIARQIVIQDCIGKGRYGEVYRGKWRG------ESVAVKIFSS--RE
ALK2_Spur_STKR1      ----SGLPYLVQRTVARQINLLQQVGKGRYGEVWMGTWQG------DTVAVKIFSS--ID
BMPR1_Spur_STKR1     ----SGLPLLVQRTIAKQVQLIRKIGKGRYGEVWKAKWRG------ENVAVKIYFT--AE
TGFbRII_Spur_STKR2   ----PDSPLHL-NGNYLPITLDELIGKGRFGAVWRAHWKINNGTKERTVAVKVFLE--YD
ACTR2_Spur_STKR2     --------TPSPMNSLPPIQLLEIKARGRFGAVWKASCLN------DIVAVKVFPI--QD
BMPR2_Spur_STKR2     ----P----PEPTFDLDQLKMMELVGQGRYCNVYRAALSE------NEVAVKVFTG--SS
AqueK680_Aque_STKR1  ----AGMPFLVKRTIARSILLGESIGGGRFGQVYVGHYQG------ERYAVKKFFS--KD
AqueK681_Aque_STKR1  ----MGERVLTSRTIAMDITIHEHLGRGTYGSISRCTYRG------NTFAVKRFTT--IN
AqueK682_Aque_STKR1  -----------------DVTKISVIGQGRFGKVWRCSYEE------KHIAMKVFKN--MH
AqueK683_Aque_STKR2  ----STL------IYSHQIV-----------TVRKA-E------NNRIIAVYKSTV--SA
AqueK684_Aque_STKR2  ----SPSP-----TLYDSPEFMKIIGHGRFARVYHARMGT------RDVAIKIFNGTLQA
AqueK685_Aque_STKR2  --ETSTIIELDEEPGLPPFQLIQSIGNGRFGSVWKALYEK------ETVAVRVFSQ--RH
AqueK686_Aque_STKR2  ---AAPNIELDERSAPLPFQLLQPIGNGRFGSVWKALYNN------ETVAVKALSL--HH
                                                     :                *:

TGFbR2_Hsap_STKR2    YASWKTEKDIFS--DIN---LKHENILQFLTAEERKT---ELGKQYWLITAFHAKGNLQE
TGFbR1_Hsap_STKR1    ERSWFREAEIYQ--TVM---LRHENILGFIAADNKDN---GTWTQLWLVSDYHEHGSLFD
MISR2_Hsap_STKR2     VAQFQAERALYE--LPG---LQHDHIVRFITASRGGPG--RLLSGPLLVLELHPKGSLCH
MISR2_Mmus_STKR2     VAQFRAERAVYQ--LLG---LQHDHIVRFITAGQGGPG--PLPSGPLLVLELYPKGSLCH
BMPR2_Mmus_STKR2     RQNFINEKNIYR--VPL---MEHDNIARFIVGDERLTA--DGRMEYLLVMEYYPNGSLCK
BMPR1B_Mmus_STKR1    EASWFRETEIYQ--TVL---MRHENILGFIAADIKGT---GSWTQLYLITDYHENGSLYD
BMPR1A_Mmus_STKR1    EASWFRETEIYQ--TVL---MRHENILGFIAADIKGT---GSWTQLYLITDYHENGSLYD
ALK7_Mmus_STKR1      ERSWFREAEIYQ--TVM---LRHENILGFIAADNKDN---GTWTQLWLVSEYHEQGSLYD
ALK4_Mmus_STKR1      ERSWFREAEIYQ--TVM---LRHENILGFIAADNKDN---GTWTQLWLVSDYHEHGSLFD
ALK2_Mmus_STKR1      EKSWFRETELYN--TVM---LRHENILGFIASDMTSR---HSSTQLWLITHYHEMGSLYD
ALK1_Mmus_STKR1      EQSWFRETEIYN--TVL---LRHDNILGFIASDMTSR---NSSTQLWLITHYHEHGSLYD
ACTR2B_Mmus_STKR2    KQSWQSEREIFS--TPG---MKHENLLQFIAAEKRGS---NLEVELWLITAFHDKGSLTD
ACTR2_Mmus_STKR2     KQSWQNEYEVYS--LPG---MKHENILQFIGAEKRGT---SVDVDLWLITAFHEKGSLSD
daf-4_Cele_STKR2     KASFLAEKRIFD--ELNEYPKWYKSIVEFVCAEKIG-------DEYWIVTEFHERLSLYE
daf-1_Cele_STKR1     EPAFHKETEIFE--TRM---LRHPNVLRYIGSDRVDT---GFVTELWLVTEYHPSGSLHD
BMPR1A_Hsap_STKR1    EASWFRETEIYQ--TVL---MRHENILGFIAADIKGT---GSWTQLYLITDYHENGSLYD
BMPR1B_Hsap_STKR1    EASWFRETEIYQ--TVL---MRHENILGFIAADIKGT---GSWTQLYLITDYHENGSLYD
BMPR2_Hsap_STKR2     RQNFINEKNIYR--VPL---MEHDNIARFIVGDERVTA--DGRMEYLLVMEYYPNGSLCK
ALK7_Hsap_STKR1      ERSWFREAEIYQ--TVM---LRHENILGFIAADNKDN---GTWTQLWLVSEYHEQGSLYD
ALK4_Hsap_STKR1      ERSWFREAEIYQ--TVM---LRHENILGFIAADNKDN---GTWTQLWLVSDYHEHGSLFD
tkv_Dmel_STKR1       EASWFRETEIYQ--TVL---MRHDNILGFIAADIKGN---GSWTQMLLITDYHEMGSLHD
put_Dmel_STKR2       KESWTTEHDIYK--LPR---MRHPNILEFLGVEKHMD-----KPEYWLISTYQHNGSLCD
SAX_Dmel_STKR1       EESWKRETEIYS--TIL---LRHENILGFIGSDMTSR---NSCTQLWLMTHYYPLGSLFD
wit_Dmel_STKR2       HQYYVNERNIYA--LPL---MECPALLSYFGYDERCTM--DGRMEYQLVLSLAPLGCLQD
BABO_Dmel_STKR1      ECSWFREAEIYQ--TVM---LRHENILGFIAADNKDN---GTWTQLWLVTDYHENGSLFD
TGFBR1_Mmus_STKR1    ERSWFREAEIYQ--TVM---LRHENILGFIAADNKDN---GTWTQLWLVSDYHEHGSLFD
TGFBR2_Mmus_STKR2    YSSWKTEKDIFS--DIN---LKHENILQFLTAEERKT---ELGKQYWLITAFHAKGNLQE
sma-6_Cele_STKR1     EDSWKNERDVYQ--TNM---INHENILQFVAADIWSEE--DSMTKMLLITDYHELGSLSD
ALK2_Hsap_STKR1      EKSWFRETELYN--TVM---LRHENILGFIASDMTSR---HSSTQLWLITHYHEMGSLYD
ALK1_Hsap_STKR1      EQSWFRETEIYN--TVL---LRHDNILGFIASDMTSR---NSSTQLWLITHYHEHGSLYD
ACTR2B_Hsap_STKR2    KQSWQSEREIFS--TPG---MKHENLLQFIAAEKRGS---NLEVELWLITAFHDKGSLTD
ACTR2_Hsap_STKR2     KQSWQNEYEVYS--LPG---MKHENILQFIGAEKRGT---SVDVDLWLITAFHEKGSLSD
TGFbR1_Spur_STKR1    ERSWFREAEIYQ--TVM---LRHENILGFIAADNKDN---GTWTQLILVSDYHENGSLFD
ALK2_Spur_STKR1      EKSWFRETEIYN--TVM---LRHENILAFFASDMTSR---QSCTQLWLIMEYHERGSLYD
BMPR1_Spur_STKR1     EASWFRETDIYQ--TVL---MRHTSILSFIAADIRGS---GAYTQLFLITEYHEWGSLYD
TGFbRII_Spur_STKR2   SASWNVEKELFTDHSVM---MRHEHIVQFISAEVRRVSVTSPTRQYWLITKYYKNGSLHD
ACTR2_Spur_STKR2     RNSWANEREIYS--LPH---MHHENLLHFIATEKHGE---GLEVEYWLISEFHHHGSLCD
BMPR2_Spur_STKR2     KQCYMNELDIMG--LPH---MEHSNLLQYVGSGDRMGE--DGWVEHLLVVDMISKGSLMS
AqueK680_Aque_STKR1  EQSWFHESDIYN--SVN---LRHDNILTCFATDMLSN---NGVTELWLITQYHPRGSLFE
AqueK681_Aque_STKR1  ESSFRRELGIYS--F-S---LTQTNILTYIAADMITI---DGVMECWLILQYCPRGSLYM
AqueK682_Aque_STKR1  MAVFKREVEIYD--TYM---LYHENILRFIGHDQIEF---ADTIELRLYTEYHENGTLQD
AqueK683_Aque_STKR2  LSQWKIERDIYL--TPE---LRHESILTLLRAKRVK-D-----IGYQLVLKGSITGSLYQ
AqueK684_Aque_STKR2  KGSWTQEKDIYA--TER---LEHENILKFLYHDHRFH---EGQDTLWLIFDYHSNGSLYD
AqueK685_Aque_STKR2  RTSWQNERDIHL--LNS---TPHENILKFISSESRGR---GPSSEYFIITEYLPLGSLHQ
AqueK686_Aque_STKR2  KLSWQNERDIHL--LDS---TPHENILKFISSESRGR---GSSSEYFIITEYLPLGSLHQ
                        :  *  :               :   .                 :         *

TGFbR2_Hsap_STKR2    YLTR-HVI-SWEDLRKLGSSLARGIAHLHSDHTP-C-G--RPKMPIVHRDLKSSNILVKN
TGFbR1_Hsap_STKR1    YLNR-YTV-TVEGMIKLALSTASGLAHLHMEIV-GT----QGKPAIAHRDLKSKNILVKK
MISR2_Hsap_STKR2     YLTQ-YTS-DWGSSLRMALSLAQGLAFLHEERWQNG----QYKPGIAHRDLSSQNVLIRE
MISR2_Mmus_STKR2     YLTQ-YTS-DWGSSLRMALSLAEGLAFLHEERWQDG----QYKPGIAHRDLSSQNVLIRE
BMPR2_Mmus_STKR2     YLSL-HTS-DWVSSCRLAHSVTRGLAYLHTELPRGD----HYKPAISHRDLNSRNVLVKN
BMPR1B_Mmus_STKR1    YLKS-TTL-DAKSMLKLAYSSVSGLCHLHTEIF-ST----QGKPAIAHRDLKSKNILVKK
BMPR1A_Mmus_STKR1    FLKC-ATL-DTRALLKLAYSAACGLCHLHTEIY-GT----QGKPAIAHRDLKSKNILIKK
ALK7_Mmus_STKR1      YLNR-NIV-TVAGMVKLALSIASGLAHLHMEIV-GT----QGKPAIAHRDIKSKNILVKK
ALK4_Mmus_STKR1      YLNR-YTV-TIEGMIKLALSAASGLAHLHMEIV-GT----QGKPGIAHRDLKSKNILVKK
ALK2_Mmus_STKR1      YLQL-TTL-DTVSCLRIVLSIASGLAHLHIEIF-GT----QGKSAIAHRDLKSKNILVKK
ALK1_Mmus_STKR1      FLQR-QTL-EPQLALRLAVSAACGLAHLHVEIF-GT----QGKPAIAHRDLKSRNVLVKS
ACTR2B_Mmus_STKR2    YLKG-NII-TWNELCHVAETMSRGLSYLHEDVP-WCRG-EGHKPSIAHRDFKSKNVLLKS
ACTR2_Mmus_STKR2     FLKA-NVV-SWNELCHIAETMARGLAYLHEDIP-GLK--DGHKPAISHRDIKSKNVLLKN
daf-4_Cele_STKR2     LLKN-NVI-SITSANRIIMSMIDGLQFLHDDRP-YFFG-H-PKKPIIHRDIKSKNILVKS
daf-1_Cele_STKR1     FLLE-NTV-NIETYYNLMRSTASGLAFLHNQIG-GSK--ESNKPAMAHRDIKSKNIMVKN
BMPR1A_Hsap_STKR1    FLKC-ATL-DTRALLKLAYSAACGLCHLHTEIY-GT----QGKPAIAHRDLKSKNILIKK
BMPR1B_Hsap_STKR1    YLKS-TTL-DAKSMLKLAYSSVSGLCHLHTEIF-ST----QGKPAIAHRDLKSKNILVKK
BMPR2_Hsap_STKR2     YLSL-HTS-DWVSSCRLAHSVTRGLAYLHTELPRGD----HYKPAISHRDLNSRNVLVKN
ALK7_Hsap_STKR1      YLNR-NIV-TVAGMIKLALSIASGLAHLHMEIV-GT----QGKPAIAHRDIKSKNILVKK
ALK4_Hsap_STKR1      YLNR-YTV-TIEGMIKLALSAASGLAHLHMEIV-GT----QGKPGIAHRDLKSKNILVKK
tkv_Dmel_STKR1       YLSM-SVI-NPQKLQLLAFSLASGLAHLHDEIF-GT----PGKPAIAHRDIKSKNILVKR
put_Dmel_STKR2       YLKS-HTI-SWPELCRIAESMANGLAHLHEEIP-ASKT-DGLKPSIAHRDFKSKNVLLKS
SAX_Dmel_STKR1       HLNR-NAL-SHNDMVWICLSIANGLVHLHTEIF-GK----QGKPAMAHRDLKSKNILVTS
wit_Dmel_STKR2       WLIA-NTL-TFSECCGMLRSITRGISHLHTELRLGD----QHKPCVAHRDINTRNVLVQA
BABO_Dmel_STKR1      YLTT-HPV-DTNTMLNMSLSIATGLAHLHMDIV-GT----RGKPAIAHRDLKSKNILVKS
TGFBR1_Mmus_STKR1    YLNR-YTV-TVEGMIKLALSTASGLAHLHMEIV-GT----QGKPAIAHRDLKSKNILVKK
TGFBR2_Mmus_STKR2    YLTR-HVI-SWEDLRKLGSSLARGIAHLHSDHTP-C-G--RPKMPIVHRDLKSSNILVKN
sma-6_Cele_STKR1     YLCREETL-TTDEALRLIHSCICGIEHLHAAVH-GTG--SFRKPEIAHRDIKSKNIIVKR
ALK2_Hsap_STKR1      YLQL-TTL-DTVSCLRIVLSIASGLAHLHIEIF-GT----QGKPAIAHRDLKSKNILVKK
ALK1_Hsap_STKR1      FLQR-QTL-EPHLALRLAVSAACGLAHLHVEIF-GT----QGKPAIAHRDFKSRNVLVKS
ACTR2B_Hsap_STKR2    YLKG-NII-TWNELCHVAETMSRGLSYLHEDVP-WCRG-EGHKPSIAHRDFKSKNVLLKS
ACTR2_Hsap_STKR2     FLKA-NVV-SWNELCHIAETMARGLAYLHEDIP-GLK--DGHKPAISHRDIKSKNVLLKN
TGFbR1_Spur_STKR1    YLNS-HVI-DVPGMLRMALSIATGLAHLHMEIM-GM----QGKPAIAHRDIKSKNILVKR
ALK2_Spur_STKR1      YLNR-HVL-DARQMCRLALTACSGLVHLHTEIT-CN----NSKPAIAHRDIKTKNILVKR
BMPR1_Spur_STKR1     FLNV-NIL-DSQSMLRLAYSAANGLAHLHTEIC-GM----QGKPAIAHRDVKSSNIMVRK
TGFbRII_Spur_STKR2   YLRQ-RSV-NWIDLCKLCGSAARGLAHLHAETYG-SHG--LHKVPVAHRDLKSTNILVKD
ACTR2_Spur_STKR2     YLKA-NVI-SWKELCGIAFSMAKGLAYLHEDIP-PTTAIPFVKHSVAHRDFKSKNVLIKN
BMPR2_Spur_STKR2     YLRE-NTY-DWHTMCRLAQTTAAGLAHLHQVIDTQV----GLKPAVVHRDINSRNVLVNA
AqueK680_Aque_STKR1  ELNR-GGL-TPETTLKFIHSTCRGLAYLHLEIT-GT----QGKPSVAHRDIKSKNILVKN
AqueK681_Aque_STKR1  ELTS-SPP-SLETGVRMVYSACMGLSYLHSSLQ-GYG--PIAKPRIAHRDIKSKNILMKT
AqueK682_Aque_STKR1  YLKS-KPVFHFPECHQMAVSLSSGLTYLHKTI-VAGK----IKPGIAHRDLKSSNILVKT
AqueK683_Aque_STKR2  YLQS-HSP-DELEAAKITHSMSSGLAHLHYMESSQSHS-KYRVITIAHCNINSHNILMKE
AqueK684_Aque_STKR2  YLQL-HRL-TFDELFSLCLSGAAGLEHLHSVDNCPET----YKPAIAHRDLKSKNILVKK
AqueK685_Aque_STKR2  FLRH-NTL-SWEQAWNIMYSITSGITHLHSSSYYS-NGLLADKFSIAHRDIKPSNILVKS
AqueK686_Aque_STKR2  FLRH-NTL-SWEQAWNIMYSIASGITHLHSNSYYNSNGLLLEKYSIAHRDIKPSNILVKS
                      *              .  :   *: .**                : * :... *:::

TGFbR2_Hsap_STKR2    -DLTCCLCDFGLSLRL--------------------------------------------
TGFbR1_Hsap_STKR1    -NGTCCIADLGLAVRH--------------------------------------------
MISR2_Hsap_STKR2     -DGSCAIGDLGLALVL--------------------------------------------
MISR2_Mmus_STKR2     -DRSCAIGDLGLALVL--------------------------------------------
BMPR2_Mmus_STKR2     -DGACVISDFGLSMRL--------------------------------------------
BMPR1B_Mmus_STKR1    -NGTCCIADLGLAVKF--------------------------------------------
BMPR1A_Mmus_STKR1    -NGSCCIADLGLAVKF--------------------------------------------
ALK7_Mmus_STKR1      -CDTCAIADLGLAVKH--------------------------------------------
ALK4_Mmus_STKR1      -NGMCAIADLGLAVRH--------------------------------------------
ALK2_Mmus_STKR1      -NGQCCIADLGLAVMH--------------------------------------------
ALK1_Mmus_STKR1      -NLQCCIADLGLAVMH--------------------------------------------
ACTR2B_Mmus_STKR2    -DLTAVLADFGLAVRF--------------------------------------------
ACTR2_Mmus_STKR2     -NLTACIADFGLALKF--------------------------------------------
daf-4_Cele_STKR2     -DMTTCIADFGLARIY--------------------------------------------
daf-1_Cele_STKR1     -DLTCAIGDLGLSLSK--------------------------------------------
BMPR1A_Hsap_STKR1    -NGSCCIADLGLAVKF--------------------------------------------
BMPR1B_Hsap_STKR1    -NGTCCIADLGLAVKF--------------------------------------------
BMPR2_Hsap_STKR2     -DGTCVISDFGLSMRL--------------------------------------------
ALK7_Hsap_STKR1      -CETCAIADLGLAVKH--------------------------------------------
ALK4_Hsap_STKR1      -NGMCAIADLGLAVRH--------------------------------------------
tkv_Dmel_STKR1       -NGQCAIADFGLAVKY--------------------------------------------
put_Dmel_STKR2       -DLTACIADFGLAMIF--------------------------------------------
SAX_Dmel_STKR1       -NGSCVIADFGLAVTH--------------------------------------------
wit_Dmel_STKR2       -DLSCCIADFGFALKV--------------------------------------------
BABO_Dmel_STKR1      -NLSCAIGDLGLAVRH--------------------------------------------
TGFBR1_Mmus_STKR1    -NGTCCIADLGLAVRH--------------------------------------------
TGFBR2_Mmus_STKR2    -DLTCCLCDFGLSLRL--------------------------------------------
sma-6_Cele_STKR1     -PNVCCIADLGLALRY--------------------------------------------
ALK2_Hsap_STKR1      -NGQCCIADLGLAVMH--------------------------------------------
ALK1_Hsap_STKR1      -NLQCCIADLGLAVMH--------------------------------------------
ACTR2B_Hsap_STKR2    -DLTAVLADFGLAVRF--------------------------------------------
ACTR2_Hsap_STKR2     -NLTACIADFGLALKF--------------------------------------------
TGFbR1_Spur_STKR1    -NGQCAIADLGLAVRH--------------------------------------------
ALK2_Spur_STKR1      -NLTCCIADLGLAVLH--------------------------------------------
BMPR1_Spur_STKR1     -NGTCMIADMSLAARFLSEGNEIDLGQNTRLGTTRYLPPEVLDNVLMSNTFDAFKMADMY
TGFbRII_Spur_STKR2   -DGSCAIADFGLAIRL--------------------------------------------
ACTR2_Spur_STKR2     -NTTACIADFGLACVF--------------------------------------------
BMPR2_Spur_STKR2     -EGNCVIGDFGFAMQV--------------------------------------------
AqueK680_Aque_STKR1  -DSTCCIADFGLAVNY--------------------------------------------
AqueK681_Aque_STKR1  -AETCCIADFGLSIAD--------------------------------------------
AqueK682_Aque_STKR1  -DYTLCIADLGLAIKQ--------------------------------------------
AqueK683_Aque_STKR2  -DGTVFLSDFSRSVKF--------------------------------------------
AqueK684_Aque_STKR2  -DMTCCISDFGLAIKF--------------------------------------------
AqueK685_Aque_STKR2  PSGQCVVADFGQAFVL--------------------------------------------
AqueK686_Aque_STKR2  VSGHCVVADLGLAFIL--------------------------------------------
                           : *:. :

TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ------------------------------------------------------------
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     ------------------------------------------------------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ------------------------------------------------------------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ------------------------------------------------------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     SFGMVLWEIARRCVTRGFIAADIRGSGAYTQLFLITEYHEWGSLYDFLNVNILDSQSMLR
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     ------------------------------------------------------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  ------------------------------------------------------------
AqueK685_Aque_STKR2  ------------------------------------------------------------
AqueK686_Aque_STKR2  ------------------------------------------------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------DPTLS-
TGFbR1_Hsap_STKR1    ------------------------------------------------------DSATD-
MISR2_Hsap_STKR2     ------------------------------------------------------PGLTQP
MISR2_Mmus_STKR2     ------------------------------------------------------PGLAQP
BMPR2_Mmus_STKR2     ------------------------------------------------------TGNRLV
BMPR1B_Mmus_STKR1    ------------------------------------------------------ISDTN-
BMPR1A_Mmus_STKR1    ------------------------------------------------------NSDTN-
ALK7_Mmus_STKR1      ------------------------------------------------------DSIMN-
ALK4_Mmus_STKR1      ------------------------------------------------------DAVTD-
ALK2_Mmus_STKR1      ------------------------------------------------------SQSTN-
ALK1_Mmus_STKR1      ------------------------------------------------------SQSSD-
ACTR2B_Mmus_STKR2    ------------------------------------------------------EPGKP-
ACTR2_Mmus_STKR2     ------------------------------------------------------EAGKS-
daf-4_Cele_STKR2     ------------------------------------------------------SYDIE-
daf-1_Cele_STKR1     ------------------------------------------------------PEDAAS
BMPR1A_Hsap_STKR1    ------------------------------------------------------NSDTN-
BMPR1B_Hsap_STKR1    ------------------------------------------------------ISDTN-
BMPR2_Hsap_STKR2     ------------------------------------------------------TGNRLV
ALK7_Hsap_STKR1      ------------------------------------------------------DSILN-
ALK4_Hsap_STKR1      ------------------------------------------------------DAVTD-
tkv_Dmel_STKR1       ------------------------------------------------------NSELD-
put_Dmel_STKR2       ------------------------------------------------------QPGKP-
SAX_Dmel_STKR1       ------------------------------------------------------SHVTG-
wit_Dmel_STKR2       ------------------------------------------------------FGSKYE
BABO_Dmel_STKR1      ------------------------------------------------------VEKND-
TGFBR1_Mmus_STKR1    ------------------------------------------------------DSATD-
TGFBR2_Mmus_STKR2    ------------------------------------------------------DPTLS-
sma-6_Cele_STKR1     ------------------------------------------------------QNDK-I
ALK2_Hsap_STKR1      ------------------------------------------------------SQSTN-
ALK1_Hsap_STKR1      ------------------------------------------------------SQGSD-
ACTR2B_Hsap_STKR2    ------------------------------------------------------EPGKP-
ACTR2_Hsap_STKR2     ------------------------------------------------------EAGKS-
TGFbR1_Spur_STKR1    ------------------------------------------------------DSVTD-
ALK2_Spur_STKR1      ------------------------------------------------------TQRED-
BMPR1_Spur_STKR1     LAYSAANGLAHLHTEICGMQGKPAIAHRDVKSSNIMVRKNGTCMIADMSLAARFLSEGN-
TGFbRII_Spur_STKR2   ------------------------------------------------------DPQSS-
ACTR2_Spur_STKR2     ------------------------------------------------------EAGKN-
BMPR2_Spur_STKR2     ------------------------------------------------------CGSSVV
AqueK680_Aque_STKR1  ------------------------------------------------------L-----
AqueK681_Aque_STKR1  ------------------------------------------------------SED--F
AqueK682_Aque_STKR1  ------------------------------------------------------SESGD-
AqueK683_Aque_STKR2  ------------------------------------------------------NGGI--
AqueK684_Aque_STKR2  ------------------------------------------------------DGV-D-
AqueK685_Aque_STKR2  ------------------------------------------------------DPAAD-
AqueK686_Aque_STKR2  ------------------------------------------------------DPAAD-


TGFbR2_Hsap_STKR2    ------V-DD-LANSGQVGTARYMAPEVLESRMNLENVE-SFKQTDVYSMALVLWEMTSR
TGFbR1_Hsap_STKR1    ------T-ID-IAPNHRVGTKRYMAPEVLDDSINMKHFE-SFKRADIYAMGLVFWEIARR
MISR2_Hsap_STKR2     PAWTPTQPQG-PAAIMEAGTQRYMAPELLDKTLDLQDWGMALRRADIYSLALLLWEILSR
MISR2_Mmus_STKR2     PALAPTQPRG-PAAILEAGTQRYMAPELLDKTLDLQDWGTALQRADVYSLALLLWEILSR
BMPR2_Mmus_STKR2     R---PGE-ED-NAAISEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEVFMR
BMPR1B_Mmus_STKR1    ------E-VD-IPPNTRVGTKRYMPPEVLDESLNRNHFQ-SYIMADMYSFGLILWEIARR
BMPR1A_Mmus_STKR1    ------E-VD-IPLNTRVGTKRYMAPEVLDESLNKNHFQ-PYIMADIYSFGLIIWEMARR
ALK7_Mmus_STKR1      ------T-ID-IPQNPKVGTKRYMAPEMLDDTMNLSIFE-SFKRADIYSVGLVYWEIARR
ALK4_Mmus_STKR1      ------T-ID-IAPNQRVGTKRYMAPEVLDETINMKHFD-SFKCADIYALGLVYWEIARR
ALK2_Mmus_STKR1      ------Q-LD-VGNNPRVGTKRYMAPEVLDETIQVDCFD-SYKRVDIWAFGLVLWEVARR
ALK1_Mmus_STKR1      ------Y-LD-IGNNPRVGTKRYMAPEVLDEHIRTDCFE-SYKWTDIWAFGLVLWEIARR
ACTR2B_Mmus_STKR2    ------P-GD---THGQVGTRRYMAPEVLEGAINFQR-D-AFLRIDMYAMGLVLWELVSR
ACTR2_Mmus_STKR2     ------A-GD---THGQVGTRRYMAPEVLEGAINFQR-D-AFLRIDMYAMGLVLWELASR
daf-4_Cele_STKR2     ------Q-SD---LLGQVGTKRYMSPEMLEGATEFTP-T-AFKAMDVYSMGLVMWEVISR
daf-1_Cele_STKR1     ------D-II-ANENYKCGTVRYLAPEILNSTMQFTVFE-SYQCADVYSFSLVMWETLCR
BMPR1A_Hsap_STKR1    ------E-VD-VPLNTRVGTKRYMAPEVLDESLNKNHFQ-PYIMADIYSFGLIIWEMARR
BMPR1B_Hsap_STKR1    ------E-VD-IPPNTRVGTKRYMPPEVLDESLNRNHFQ-SYIMADMYSFGLILWEVARR
BMPR2_Hsap_STKR2     R---PGE-ED-NAAISEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMR
ALK7_Hsap_STKR1      ------T-ID-IPQNPKVGTKRYMAPEMLDDTMNVNIFE-SFKRADIYSVGLVYWEIARR
ALK4_Hsap_STKR1      ------T-ID-IAPNQRVGTKRYMAPEVLDETINMKHFD-SFKCADIYALGLVYWEIARR
tkv_Dmel_STKR1       ------V-IH-IAQNPRVGTRRYMAPEVLSQQLDPKQFE-EFKRADMYSVGLVLWEMTRR
put_Dmel_STKR2       ------C-GD---THGQVGTRRYMAPEVLEGAINFNR-D-AFLRIDVYACGLVLWEMVSR
SAX_Dmel_STKR1       ------Q-LD-LGNNPKVGTKRYMAPEVLDESIDLECFE-ALRRTDIYAFGLVLWEVCRR
wit_Dmel_STKR2       YKGEVAM-AE-TKSINEVGTLRYMAPELLEGAVNLRDCETSLKQMDVYALGLVLWEVATR
BABO_Dmel_STKR1      ------S-VD-IPSTHRVGTKRYMAPEVLDESMNDQHFD-SYKRADVYAFGLILWEIARR
TGFBR1_Mmus_STKR1    ------T-ID-IAPNHRVGTKRYMAPEVLDDSINMKHFE-SFKRADIYAMGLVFWEIARR
TGFBR2_Mmus_STKR2    ------V-DD-LANSGQVGTARYMAPEVLESRMNLENVE-SFKQTDVYSMALVLWEMTSR
sma-6_Cele_STKR1     --------LP-EKFNVQVGTKRYMAPELISNKLNPKDFS-QFKMADIYSMALVMWEVAIR
ALK2_Hsap_STKR1      ------Q-LD-VGNNPRVGTKRYMAPEVLDETIQVDCFD-SYKRVDIWAFGLVLWEVARR
ALK1_Hsap_STKR1      ------Y-LD-IGNNPRVGTKRYMAPEVLDEQIRTDCFE-SYKWTDIWAFGLVLWEIARR
ACTR2B_Hsap_STKR2    ------P-GD---THGQVGTRRYMAPEVLEGAINFQR-D-AFLRIDMYAMGLVLWELVSR
ACTR2_Hsap_STKR2     ------A-GD---THGQVGTRRYMAPEVLEGAINFQR-D-AFLRIDMYAMGLVLWELASR
TGFbR1_Spur_STKR1    ------T-VD-IFPNNRIGTKRYMAPEVLDDTINMNHFD-SFKRADVYSFGLVLWEIGRR
ALK2_Spur_STKR1      ------N-ID-MGTNTRVGTKRYMAPELLEETMDVRCFE-SFKRVDVYAFGLVMWEIARR
BMPR1_Spur_STKR1     ------E-ID-LGQNTRLGTTRYLPPEVLDNVLMSNTFD-AFKMADMYSFGMVLWEIARR
TGFbRII_Spur_STKR2   ------T-DH-LANSGQVGTPRYMSPEALECKVNLQDIE-SFKQMDTYALALILWEITSR
ACTR2_Spur_STKR2     ------P-GD---THGQVGTRRYMAPEVLEGAIQFKR-D-AFLRIDMYAFGLVLWELVTR
BMPR2_Spur_STKR2     G---EGD-GD-NSTITDVGTVRYMSPEVLDGAVNLRDCECALKQVDVYALGLVVWEIAMR
AqueK680_Aque_STKR1  ---------N-FNNNVQQGTKRYMPPEVIKGTIDVHSFE-SFLRADIYSFGLVMWEVCTR
AqueK681_Aque_STKR1  ------Q-S---FICLKQGTNRYMAPEILNETIDVKDFV-SFLRADVYSFALVAWEVFNR
AqueK682_Aque_STKR1  ------G-VDQIPANKLSGTKRYMSPEILNESLDYGRFI-CYAQSDIYSFSLIIWEIFNC
AqueK683_Aque_STKR2  --------IA-VGRDSEVIILGICLPEVLQGFQSF-TIT-SLTNSDIYSLGLCIWEVLNC
AqueK684_Aque_STKR2  ------M-IL-SEAKGQVGTSRYMAPEILEGAVRFNQ-E-AFLKIDIYAFGLILWEMLSC
AqueK685_Aque_STKR2  ------D-RK-LAVSGQVGTYRYMSPEALDARVNLRDSE-SFKQIDVYAMSLVLWEVCMR
AqueK686_Aque_STKR2  ------D-RK-LAVSGQVGTYRYMSPEALDARVNLRDIE-SFKQIDMYALSLVLWEVCMR
                                              ** :.               * :: .:  **

TGFbR2_Hsap_STKR2    CNAV-------------------------------------------------GEV---K
TGFbR1_Hsap_STKR1    CSIG-------------------------------------------------GIH---E
MISR2_Hsap_STKR2     CPDL--RP--------------------------------------------DSSP---P
MISR2_Mmus_STKR2     CSDL--RP--------------------------------------------DHRP---P
BMPR2_Mmus_STKR2     CTDL--FP--------------------------------------------GESV---P
BMPR1B_Mmus_STKR1    CVSG-------------------------------------------------GIV---E
BMPR1A_Mmus_STKR1    CITG-------------------------------------------------GIV---E
ALK7_Mmus_STKR1      CSVG-------------------------------------------------GVV---E
ALK4_Mmus_STKR1      CNSG-------------------------------------------------GVH---E
ALK2_Mmus_STKR1      MVSN-------------------------------------------------GIV---E
ALK1_Mmus_STKR1      TIIN-------------------------------------------------GIV---E
ACTR2B_Mmus_STKR2    CKAA-D-----------------------------------------------GPV---D
ACTR2_Mmus_STKR2     CTAA-D-----------------------------------------------GPV---D
daf-4_Cele_STKR2     TKLHQT-----------------------------------------------DEP---P
daf-1_Cele_STKR1     CED--G-----------------------------------------------DVLPREA
BMPR1A_Hsap_STKR1    CITG-------------------------------------------------GIV---E
BMPR1B_Hsap_STKR1    CVSG-------------------------------------------------GIV---E
BMPR2_Hsap_STKR2     CTDL--FP--------------------------------------------GESV---P
ALK7_Hsap_STKR1      CSVG-------------------------------------------------GIV---E
ALK4_Hsap_STKR1      CNSG-------------------------------------------------GVH---E
tkv_Dmel_STKR1       CYTPVSGTK-------------------------------------------TTTC---E
put_Dmel_STKR2       CDF--A-----------------------------------------------GPV---G
SAX_Dmel_STKR1       TISC-------------------------------------------------GIA---E
wit_Dmel_STKR2       CSDFY-AP--------------------------------------------GQAT---P
BABO_Dmel_STKR1      CNMG-------------------------------------------------MIY---D
TGFBR1_Mmus_STKR1    CSIG-------------------------------------------------GIH---E
TGFBR2_Mmus_STKR2    CNAV-------------------------------------------------GEV---K
sma-6_Cele_STKR1     VEVN--TCEEVLTVDETSPDHSASSGIGESVSSSGNISRMHLQKTNVEGHSTSLKA---K
ALK2_Hsap_STKR1      MVSN-------------------------------------------------GIV---E
ALK1_Hsap_STKR1      TIVN-------------------------------------------------GIV---E
ACTR2B_Hsap_STKR2    CKAA-D-----------------------------------------------GPV---D
ACTR2_Hsap_STKR2     CTAA-D-----------------------------------------------GPV---D
TGFbR1_Spur_STKR1    CQVF-------------------------------------------------GIY---E
ALK2_Spur_STKR1      CEVG-------------------------------------------------GMV---A
BMPR1_Spur_STKR1     CVTR-------------------------------------------------GIV---E
TGFbRII_Spur_STKR2   CTLL-------------------------------------------------KDI---N
ACTR2_Spur_STKR2     CTVQ-D-----------------------------------------------GPV---P
BMPR2_Spur_STKR2     CKDL--YP--------------------------------------------RDEM---G
AqueK680_Aque_STKR1  CHLE-------------------------------------------------GPL---A
AqueK681_Aque_STKR1  CNIEQG-----------------------------------------------GIA---R
AqueK682_Aque_STKR1  CEID-------------------------------------------------GV---PR
AqueK683_Aque_STKR2  CQIT-------------------------------------------------G-----N
AqueK684_Aque_STKR2  CDLN-------------------------------------------------NITS-NP
AqueK685_Aque_STKR2  YQSN-------------------------------------------------DV-P-VP
AqueK686_Aque_STKR2  YQSD-------------------------------------------------DV-P-VP


TGFbR2_Hsap_STKR2    DYEPPFGSKVRE-HPCVESMKDNVLRDRGRPEIPSFWLNHQ-GIQMVCETLTECWDHDPE
TGFbR1_Hsap_STKR1    DYQLPYYDLVPS-DPSVEEMRKVVCEQKLRPNIPNRWQSCE-ALRVMAKIMRECWYANGA
MISR2_Hsap_STKR2     PFQLAYEAELGN-TPTSDELWALAVQERRRPYIPSTWRCFATDPDGLRELLEDCWDADPE
MISR2_Mmus_STKR2     PFQLAYEAELGS-NPSACELWALAVEERKRPNIPSTWSCSATDPRGLRELLEDCWDADPE
BMPR2_Mmus_STKR2     DYQMAFQTEVGN-HPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAE
BMPR1B_Mmus_STKR1    EYQLPYHDLVPS-DPSYEDMREIVCMKKLRPSFPNRWSSDE-CLRQMGKLMTECWAQNPA
BMPR1A_Mmus_STKR1    EYQLPYYNMVPS-DPSYEDMREVVCVKRLRPIVSNRWNSDE-CLRAVLKLMSECWAHNPA
ALK7_Mmus_STKR1      EYQLPYYDMVPS-DPSIEEMRKVVCDQKLRPNLPNQWQSCE-ALRVMGRIMRECWYANGA
ALK4_Mmus_STKR1      DYQLPYYDLVPS-DPSIEEMRKVVCDQKLRPNVPNWWQSYE-ALRVMGKMMRECWYANGA
ALK2_Mmus_STKR1      DYKPPFYDVVPN-DPSFEDMRKVVCVDQQRPNIPNRWFSDP-TLTSLAKLMKECWYQNPS
ALK1_Mmus_STKR1      DYRPPFYDMVPN-DPSFEDMKKVVCVDQQTPTIPNRLAADP-VLSGLAQMMRECWYPNPS
ACTR2B_Mmus_STKR2    EYMLPFEEEIGQ-HPSLEELQEVVVHKKMRPTIKDHWLKHP-GLAQLCVTIEECWDHDAE
ACTR2_Mmus_STKR2     EYMLPFEEEIGQ-HPSLEDMQEVVVHKKKRPVLRDYWQKHA-GMAMLCETIEECWDHDAE
daf-4_Cele_STKR2     NYQMPFQ-VIGF-DPTIGLMRNYVVSKKERPQWRDEIIKHE-YMSLLKKVTEEMWDPEAC
daf-1_Cele_STKR1     ATVIPYIEWTDR-DPQDAQMFDVVCTRRLRPTENPLWKDHP-EMKHIMEIIKTCWNGNPS
BMPR1A_Hsap_STKR1    EYQLPYYNMVPS-DPSYEDMREVVCVKRLRPIVSNRWNSDE-CLRAVLKLMSECWAHNPA
BMPR1B_Hsap_STKR1    EYQLPYHDLVPS-DPSYEDMREIVCIKKLRPSFPNRWSSDE-CLRQMGKLMTECWAHNPA
BMPR2_Hsap_STKR2     EYQMAFQTEVGN-HPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAE
ALK7_Hsap_STKR1      EYQLPYYDMVPS-DPSIEEMRKVVCDQKFRPSIPNQWQSCE-ALRVMGRIMRECWYANGA
ALK4_Hsap_STKR1      EYQLPYYDLVPS-DPSIEEMRKVVCDQKLRPNIPNWWQSYE-ALRVMGKMMRECWYANGA
tkv_Dmel_STKR1       DYALPYHDVVPS-DPTFEDMHAVVCVKGFRPPIPSRWQEDD-VLATVSKIMQECWHPNPT
put_Dmel_STKR2       EFQLPFEAELGL-RPSLDEVQESVVMKKLRPRLLNSWRAHP-GLNVFCDTMEECWDHDAE
SAX_Dmel_STKR1       EYKVPFYDVVPM-DPSFEDMRKVVCIDNYRPSIPNRWSSDS-LMTGMSKLMKECWHQNPD
wit_Dmel_STKR2       PYKAPYEQEVGS-HPSFDQMQALVVRHKARPLFPTGWGGGA-AAKVVRDTCEDCWDHDAD
BABO_Dmel_STKR1      EYQLPYYDVVQP-DPSIEEMKKVVCIEKCRPNIPNRWHASD-VLHNMAKVMKECWYPNPV
TGFBR1_Mmus_STKR1    DYQLPYYDLVPS-DPSVEEMRKVVCEQKLRPNIPNRWQSCE-ALRVMAKIMRECWYANGA
TGFBR2_Mmus_STKR2    DYEPPFGSKVRE-HPCVESMKDSVLRDRGRPEIPSFWLNHQ-GIQIVCETLTECWDHDPE
sma-6_Cele_STKR1     QHVPPFDGIVHN-DPNFDEMNDVICVRRIRPPPDLAWKNVP-ALNELSKLMEDSWHSIPH
ALK2_Hsap_STKR1      DYKPPFYDVVPN-DPSFEDMRKVVCVDQQRPNIPNRWFSDP-TLTSLAKLMKECWYQNPS
ALK1_Hsap_STKR1      DYRPPFYDVVPN-DPSFEDMKKVVCVDQQTPTIPNRLAADP-VLSGLAQMMRECWYPNPS
ACTR2B_Hsap_STKR2    EYMLPFEEEIGQ-HPSLEELQEVVVHKKMRPTIKDHWLKHP-GLAQLCVTIEECWDHDAE
ACTR2_Hsap_STKR2     EYMLPFEEEIGQ-HPSLEDMQEVVVHKKKRPVLRDYWQKHA-GMAMLCETIEECWDHDAE
TGFbR1_Spur_STKR1    EFCLPYHPWVPM-DPPIDDMRRIVCIEKRRPPVPNRWNSHK-IMESYAKVMKECWYQNGA
ALK2_Spur_STKR1      DYKPPFFEYVPS-DPSFDDMRKVACIEKLRPNIPNRWTNNT-VLTSMAKLMKECWCPTAS
BMPR1_Spur_STKR1     ECQLPFYDAVPM-DPSIQDMMRVVVIERRRPDIPNRWSGDD-ILRTISKVMSECWNQNPA
TGFbRII_Spur_STKR2   EYELPFSRSLGDRRASLEMMKTLVVLRRERPPITDEWLRNP-GLTIIKNTVVDCWDEDPE
ACTR2_Spur_STKR2     EYRLPFEEELGQ-GTSLEDMQEWVVVKRKRPVISDHWLKHR-GLELLCETIEECWDQDAE
BMPR2_Spur_STKR2     NYQMPFEEQVGL-HPTFEDMQILVSRERKRPQFPDAWKQNSQALRSLKETIEDCWDHDAE
AqueK680_Aque_STKR1  DYALPFQSQVPP-DPTLDDMTEFIVGKEVIPEIPETWSNNE-LLRGMSRVMYECWYHQPT
AqueK681_Aque_STKR1  EYQLPYSDHLPN-NSSIEDCRRVVVEEGTRPV-TSEWSKTR-FLEKLSVTIKELWAERGS
AqueK682_Aque_STKR1  SYQLPYCEWVPT-DPDIDQMKQCVCVNNRRPTIPDSWTESE-TLSPIAKLLDSSWATQAS
AqueK683_Aque_STKR2  SYTPPFHEVSDS-DISMDIMRSMIVEQGIVPALPAVFDEIK-EFSSVRNTVSECFDLEPE
AqueK684_Aque_STKR2  SYYPPFDGWVSA-NPSIDEMKRIVVEEKKRPPIPQKFQTNL-KYSFIADIIVECWDDDAD
AqueK685_Aque_STKR2  PYQSPFFDMVGE-KPTLDQMKEIVVINKQRPLLPEKWNNDK-NLKRIIKLIVEGWDEDPE
AqueK686_Aque_STKR2  PYQSPFFDMVGE-KPTLEQMKEIVVNANKRPGFTGVWYSDK-NLKRIIKLIKEGWDEDPE
                         .:                        *                       :

TGFbR2_Hsap_STKR2    ARLTAQCVAERFSE-LEHLDRLSGR-----------------------------------
TGFbR1_Hsap_STKR1    ARLTALRIKKTLSQ-LSQQE----------------------------------------
MISR2_Hsap_STKR2     ARLTAECVQQRLAA-LAHPQESHPF--PESCPR---------------------------
MISR2_Mmus_STKR2     ARLTAECVQQRLAA-LAYPHGASSF--PES------------------------------
BMPR2_Mmus_STKR2     ARLTAQCAEERMAE-LMMIWERNKSVSPTVNPMSTAMQNER-------NLSHNRRVPKIG
BMPR1B_Mmus_STKR1    SRLTALRVKKTLAK-MSESQ----------------------------------------
BMPR1A_Mmus_STKR1    SRLTALRIKKTLAK-MVESQ----------------------------------------
ALK7_Mmus_STKR1      ARLTALRVKKTISQ-LCVKE----------------------------------------
ALK4_Mmus_STKR1      ARLTALRIKKTLSQ-LSVQE----------------------------------------
ALK2_Mmus_STKR1      ARLTALRIKKTLTK-IDNSLD---------------------------------------
ALK1_Mmus_STKR1      ARLTALRIKKTLQK-LSHNPE---------------------------------------
ACTR2B_Mmus_STKR2    ARLSAGCVEERVSL-IRRSVNGTTS-----------------------------------
ACTR2_Mmus_STKR2     ARLSAGCVGERITQ-MQRLTNIITT-----------------------------------
daf-4_Cele_STKR2     ARITAGCAFARVWNHIMSSPDSS--EG---Y-----------------------------
daf-1_Cele_STKR1     ARFTSYICRKRMDE-RQQLLLDKK------------------------------------
BMPR1A_Hsap_STKR1    SRLTALRIKKTLAK-MVESQ----------------------------------------
BMPR1B_Hsap_STKR1    SRLTALRVKKTLAK-MSESQ----------------------------------------
BMPR2_Hsap_STKR2     ARLTAQCAEERMAE-LMMIWERNKSVSPTVNPMSTAMQNER-------NLSHNRRVPKIG
ALK7_Hsap_STKR1      ARLTALRIKKTISQ-LCVKE----------------------------------------
ALK4_Hsap_STKR1      ARLTALRIKKTLSQ-LSVQE----------------------------------------
tkv_Dmel_STKR1       VRLTALRVKKTLGR-LETDCLID-------------------------------------
put_Dmel_STKR2       ARLSSSCVMERFAQ-LNKYPSTQL------------------------------------
SAX_Dmel_STKR1       VRLPALRIKKTIHK-LASADEKIR------------------------------------
wit_Dmel_STKR2       ARLTSLCAEERMQE-MSTLRPRAQA-QPSS-PLL----NTN-------N---------LV
BABO_Dmel_STKR1      ARLTALRIKKTLAS-ISVED----------------------------------------
TGFBR1_Mmus_STKR1    ARLTALRIKKTLSQ-LSQQE----------------------------------------
TGFBR2_Mmus_STKR2    ARLTAQCVAERFSE-LEHPERLSGR-----------------------------------
sma-6_Cele_STKR1     FRHSALKLKKEMAE-LIKNPDRQNQS----------------------------------
ALK2_Hsap_STKR1      ARLTALRIKKTLTK-IDNSLD---------------------------------------
ALK1_Hsap_STKR1      ARLTALRIKKTLQK-ISNSPE---------------------------------------
ACTR2B_Hsap_STKR2    ARLSAGCVEERVSL-IRRSVNGTTS-----------------------------------
ACTR2_Hsap_STKR2     ARLSAGCVGERITQ-MQRLTNIITT-----------------------------------
TGFbR1_Spur_STKR1    ARLTALRIKKTLAG-LMGPSEPEV------------------------------------
ALK2_Spur_STKR1      ARHTSLRVKKTLMK-ISETCPKLT------------------------------------
BMPR1_Spur_STKR1     ARVTSLRVKKTLGK-LQEN-----------------------------------------
TGFbRII_Spur_STKR2   ARLTASCVEARFQE-LILWHEGEPH-----------------------------------
ACTR2_Spur_STKR2     ARLSAGCVEERIAQ-FSHSHMNGHMNG---H-----------------------------
BMPR2_Spur_STKR2     ARLTALCVEERIIE-LMVLWDKHRMISPTINPTTQGN---AIPTHTMNEYTTRPTDIISR
AqueK680_Aque_STKR1  ARPSAYYIRKKVDK-IAEMCEVR-------------------------------------
AqueK681_Aque_STKR1  ERPSIELLRKKIEK-EARTYDDCN------------------------------------
AqueK682_Aque_STKR1  SRISALRISKILKG-IDFK-----------------------------------------
AqueK683_Aque_STKR2  ARPNSHILKNLFSK-LLHDLLEKKSS----------------------------------
AqueK684_Aque_STKR2  GRPAASLISRRLSE-FQTAGYTASPHL---PPLSNKSSK---------------------
AqueK685_Aque_STKR2  ARLTAANIKIQLES-LVGMRPKPPPSS---T--S--------------------------
AqueK686_Aque_STKR2  ARLTAANIKIQLES-LIGMRPKLDSLS---SPLS--------------------------
                      *         .

TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     PYP-------------------------DYSSSSYIEDSIHHTDSIVKNISSEHSMSST-
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     -----------------------------------------------------HSGS---
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     PYP-------------------------DYSSSSYIEDSIHHTDSIVKNISSEHSMSST-
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       AS-------------------------------PTAEQGINIIATTTTAAAVHHQMSSDT
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     -----------------------------------------------------HPVS---
BMPR2_Spur_STKR2     EYPGIARLADGTMIAVRSNGQPVLGAASE----------TSGTA---SDTKNHHGLHSS-
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  -------------------------------------------------ESGFHSLSGQ-
AqueK685_Aque_STKR2  ------------------------------------------------------------
AqueK686_Aque_STKR2  ------------------------------------------------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ------------PLTIG-----------------------------------------EK
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     --------------------------------------SMKNRGVDDVEQSEKPEGIEEM
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ------------PLTIG-----------------------------------------EK
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       TGLIQPPPNQQIPLAAL-----------------------------------------ER
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     --------------------------------------P-------------TPLIMQ--
BMPR2_Spur_STKR2     ---------VSSGLEKN-----------------------------------------E-
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  ------------PLLSSSGVNNDALATDYNINTPLPPTP-------------TPSSPS--
AqueK685_Aque_STKR2  ----------------------------------------------------QPDGRN--
AqueK686_Aque_STKR2  --------------------------------------P-------------PPEGEG--


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     NRNSINYERQQA---QARIPSPETSVTSLSTNTTTTNTTGLTPSTGMTTISEMPYPDET-
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     QHYHASSPSK--------------------------------------------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     NRNSINYERQQA---QARIPSPETSVTSLSTNTTTTNTTGLTPSTGMTTISEMPYPDET-
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       EKNHLSYPQQQLQPYQGRNPCQERNLAP--------------------------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     -TMHNSTSF---------------------------------------------------
BMPR2_Spur_STKR2     ---------------RLRLMSPGTISTSLSSQ-SDLNLIDLTASAPPVDPKNLHHSDDSI
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  ---------ITLSPT---------------------------------------------
AqueK685_Aque_STKR2  ---------NFLSPI---------------------------------------------
AqueK686_Aque_STKR2  ---------VFLSPV---------------------------------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     --------------GCPPLC----PED---------------------------------
MISR2_Mmus_STKR2     ----------------PQGC----PEN---------------------------------
BMPR2_Mmus_STKR2     HLHATNVA---QSIGPTPVCLQLTEEDLETNKLDPKEVDKNLKESSDENLMEH-------
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     ------------------------------------------------------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     NLHTTNVA---QSIGPTPVCLQLTEEDLETNKLDPKEVDKNLKESSDENLMEH-------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ----------------------------LTMRTPPVLVERSKKHSFQTQPQEN-------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     ERYTTDLKYGPQQSGP-KYCDQYGFSEPSTSPSRPLVVNEMRAGLSKDQMTDNLSHGMGK
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  ------------------------------------------------EIKSH-------
AqueK685_Aque_STKR2  ------------------------------------------------LE----------
AqueK686_Aque_STKR2  ------------------------------------------------SE----------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ---------SLKQFSGPDPLSSTSSSLLYPLIKLAVEVTGQQDF-------------TQA
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     -----------RQHPSPNPFF---------------------------------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ---------SLKQFSGPDPLSSTSSSLLYPLIKLAVEATGQQDF-------------TQT
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ---------SLS--------------------CLEHDVSVEELIASHQHQQQKNTIVSTG
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     LKNKSSSMPSWNHINGVDPRSRGANQ-PVNMAKLDTNLHRQQARSASPKQSNQNGYEASG
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  ---------TVHDFSSSSTSS---------------------------------------
AqueK685_Aque_STKR2  ------------------SSE---------------------------------------
AqueK686_Aque_STKR2  ------------------TSH---------------------------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     -----C------------------------------------------------------
MISR2_Mmus_STKR2     -----C------------------------------------------------------
BMPR2_Mmus_STKR2     ANGQAC------------------------------------------------------
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     ---DSCPPPPPIPVILENGG---ILQPDNAEPEPE-------------------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ANGQAC------------------------------------------------------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       GNGNSC------------------------------------------------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     SSGASS------------------------------------------------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  ---SSCPTRSSLPIHFSPAKKSDTS-----------------------------------
AqueK685_Aque_STKR2  ---SSCKKY-RLSSS-----FSESSGNAVIFSNP---SSKLSGRFSVDH-TNNASSHRT-
AqueK686_Aque_STKR2  ---SSCKKV-HISAS-----FSGSTNA---MLSPAAAPHSFHGRFSLDHGGHNPVTVSMI


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ------------------------------------------------------------
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     -ELPDLPI---------------VEK--IY-----DIA---------------------T
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ------------------------------------------------------------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ------------------------------------------------------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     ------------------------------------------------------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  ----DP---------------RSRKA--VT-----PLRSNPG-KPTDLGSGNISGGDLFS
AqueK685_Aque_STKR2  -ILNDLR---RYRDGIG--LSN--NISTTTTDSTQ---------PNG----AYTGGG--S
AqueK686_Aque_STKR2  LSLSDVQVQYRPPDTVATANSE--SIT---VPALIPQ-SEPTTAPQL---------A--S


TGFbR2_Hsap_STKR2    ------S-----------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     --------T--S--------IPAPTILPCRPQ----------RSA---------------
MISR2_Mmus_STKR2     --------L--S--------APASAVFPCRPQ----------QSS---------------
BMPR2_Mmus_STKR2     --------LIPDVPPAQIYPLPKQQNLPKRPT----------SLPLN-TKNSTKEPRLKF
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------D-----------------------------------------------------
ACTR2_Mmus_STKR2     ------E-----------------------------------------------------
daf-4_Cele_STKR2     NMLFSRE-----------------------------------------------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     --------LIPDVLPTQIYPLPKQQNLPKRPT----------SLPLN-TKNSTKEPRLKF
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       --------LGQG--------FPKQQNTDQKLRGWHGVRALIHKKL--------------F
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------S-----------------------------------------------------
sma-6_Cele_STKR1     ------Q-----------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------D-----------------------------------------------------
ACTR2_Hsap_STKR2     ------E-----------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------A-----------------------------------------------------
ACTR2_Spur_STKR2     ------E-----------------------------------------------------
BMPR2_Spur_STKR2     --------EGA--------GPSSIPNMNIRPN----------SLPLQSTHRGSKKKLMAV
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------S-----------------------------------------------------
AqueK684_Aque_STKR2  -----QYDLSSSSGAGDVVSPLCD------------------------------------
AqueK685_Aque_STKR2  -----R-----------------D------------------------------------
AqueK686_Aque_STKR2  -----N-----------------N------------------------------------


TGFbR2_Hsap_STKR2    -------------------------C----------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     -------------------------C----------------------------------
MISR2_Mmus_STKR2     -------------------------C----------------------------------
BMPR2_Mmus_STKR2     GNKHKSNL-KQVETGVAKMNTI-----------------------NAAEPHVVTVTMNGV
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    -------------------------C----------------------------------
ACTR2_Mmus_STKR2     -------------------------D----------------------------------
daf-4_Cele_STKR2     -------------------------E----------------------------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     GSKHKSNL-KQVETGVAKMNTI-----------------------NAAEPHVVTVTMNGV
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       RKEHAEELCRQLQLGEEKSNLV-----------------------TAL------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    -------------------------C----------------------------------
sma-6_Cele_STKR1     -------------------------R----------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    -------------------------C----------------------------------
ACTR2_Hsap_STKR2     -------------------------D----------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   -------------------------Q----------------------------------
ACTR2_Spur_STKR2     -------------------------N----------------------------------
BMPR2_Spur_STKR2     YNPNTGPT-TKVQTGIAKMDSVAPSCHQVKMAANTHKQQPTHNAVEKLR-----------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  -------------------------P----------------------------------
AqueK684_Aque_STKR2  -------------------------D----------------------------------
AqueK685_Aque_STKR2  -------------------------E----------------------------------
AqueK686_Aque_STKR2  -------------------------E----------------------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     AGRSHNVNSHAATTQYAN----------------------------------GAVPAGQA
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     ------------------------------------------------------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     AGRNHSVNSHAATTQYAN----------------------------------GTVLSGQT
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ------------------------------------------------------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     -----------------NGNVGNLEPEADRPHSWACDSSSGSDRSHEIDRKNGNACSGSA
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  ------------------------------------------------------------
AqueK685_Aque_STKR2  ------------------------------------------------------------
AqueK686_Aque_STKR2  ------------------------------------------------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ---------------------HF---SVQQGP--CS------------------------
MISR2_Mmus_STKR2     ---------------------LL---SVQQGP--GS------------------------
BMPR2_Mmus_STKR2     ANIVAHRSQEMLQNQFIGEDTRL---NINSSP--DEHEPL--LRREQQAGHDEGVLDRLV
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ---------------------L--------------------------------------
ACTR2_Mmus_STKR2     ---------------------I--------------------------------------
daf-4_Cele_STKR2     ---------------------L------------------------------D----LM-
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     TNIVTHRAQEMLQNQFIGEDTRL---NINSSP--DEHEPL--LRREQQAGHDEGVLDRLV
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ----------------------RRPNNLDLNPRLDKPPPDQLRSAEQRMGTPAHIVPRSL
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ---------------------K--------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ---------------------L--------------------------------------
ACTR2_Hsap_STKR2     ---------------------I--------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ---------------------T-----------------------------------GN-
BMPR2_Spur_STKR2     SCIAKGDNGKRKVTPFRLLTEKL---SIHKGK--DKKE----------------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ---------------------I--------------------------------------
AqueK684_Aque_STKR2  ---------------------V------------------------------RKFSLQL-
AqueK685_Aque_STKR2  ---------------------V------------------------------S----SS-
AqueK686_Aque_STKR2  ---------------------V------------------------------S----NG-


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------RNP---
MISR2_Mmus_STKR2     ------------------------------------------------------RSPD--
BMPR2_Mmus_STKR2     DRRERPLEGGRTNSNNNNSNPCSEQDI-----LTQ-------------GVTSTAADPGPS
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    --------------------------V-----S---------------------------
ACTR2_Mmus_STKR2     --------------------------V-----T---------------------------
daf-4_Cele_STKR2     ---------------------NAQRQV-----E---------------------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     DRRERPLEGGRTNSNNNNSNPCSEQDV-----LAQ-------------GVPSTAADPGPS
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       SSSLIKHINGTT-NNNSIQSHGSELQT-----LTRPASKRRPGHLRTNSLMATT-GQGPP
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     --------------------------V-----E---------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    --------------------------V-----S---------------------------
ACTR2_Hsap_STKR2     --------------------------V-----T---------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ---------------------TE---S-----T---------------------------
BMPR2_Spur_STKR2     ------------------------------------------------------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  --------------------------VEEEELE---------------------------
AqueK684_Aque_STKR2  ---------------------DYTEDF-----K---------------------------
AqueK685_Aque_STKR2  ---------------------ESQDEV-----N---------------------------
AqueK686_Aque_STKR2  ---------------------GSQDEV-----N---------------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     KPRRAQRPNSLDLSATNILDGSSIQIGESTQDGKSGSGEK----------------I-KR
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ---------------------------------------L----------------V---
ACTR2_Mmus_STKR2     ---------------------------------------V----------------V---
daf-4_Cele_STKR2     -----------------Y---EA------------GA--D----------------T---
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     KPRRAQRPNSLDLSATNVLDGSSIQIGESTQDGKSGSGEK----------------I-KK
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ---------------------------------------L----------------I---
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       TEQQMRRQHSLEV-------------FREVFSG-RGSSER----------------L-RD
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ---------------------------------------F----------------Q---
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ---------------------------------------L----------------V---
ACTR2_Hsap_STKR2     ---------------------------------------V----------------V---
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ---------------------------------------D----------------I---
BMPR2_Spur_STKR2     -PK-----------------------------------------------------D-Q-
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ---------------------------------------AFTGTEQTEELPSSEVVLPL-
AqueK684_Aque_STKR2  ------------------------------------------------------------
AqueK685_Aque_STKR2  -----------------V------------------------------------------
AqueK686_Aque_STKR2  -----------------VIDATT------------GQ-----------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ---RVKTPY----SLKRWRPSTWVISTEPLDC-----------EVNNNGSDRAVHSKSST
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     ------------------------------------------------------------
daf-1_Cele_STKR1     ------------------------------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ---RVKTPY----SLKRWRPSTWVISTESLDC-----------EVNNNGSNRAVHSKSST
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       PSERVKTPGDVPPSVRKARASK--------------------------------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     -----------------------------TDCNGVNNRNPVELNVNN-------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------------
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  ------------------------------------------------------------
AqueK685_Aque_STKR2  ------------------------------------------------------------
AqueK686_Aque_STKR2  ------------------------------------------------------------


TGFbR2_Hsap_STKR2    -----------------------------------------------------SE-----
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     AVYLAEGG------------------------------------------T--AT-----
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    --------------------------------------------------T--SV-----
ACTR2_Mmus_STKR2     --------------------------------------------------T--MV-----
daf-4_Cele_STKR2     --------------------------------------------------R--AS-----
daf-1_Cele_STKR1     ------------------------------------------------------A---KA
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     AVYLAEGG------------------------------------------T--AT-----
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       --------------------------------------------------K--NH-----
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ------------------------------------------------------T-----
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    -----------------------------------------------------SQ-----
sma-6_Cele_STKR1     --------------------------------------------------Q--QD-----
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    --------------------------------------------------T--SV-----
ACTR2_Hsap_STKR2     --------------------------------------------------T--MV-----
TGFbR1_Spur_STKR1    ---------------------------------------------------------LLP
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   -----------------------------------------------------SF-----
ACTR2_Spur_STKR2     --------------------------------------------------A--LY-----
BMPR2_Spur_STKR2     -----NARAIAPQTLANGSDNDSVACSDLSNGHAGVSLNGDAYPLNSKLVN--GS-----
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  ------------------------------------------------------N--LST
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  --------------------------------------------------TQHSQTGT--
AqueK684_Aque_STKR2  ------------------------------------------------------------
AqueK685_Aque_STKR2  ------------------------------------------------------------
AqueK686_Aque_STKR2  ------------------------------------------------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ------------------------------------------------------------
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     ------------------------------------------------------------
daf-1_Cele_STKR1     VAQT----------------A---------------------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ------------------------------------------------------------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ------------------------------------------------------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    PAN---------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     ------------------------------------------------------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  LIDIVQATIFIVVFRMLRLLAKIPLFGIILKSLIRVLVLLIPFLLLGYLFYFEFAIVGMA
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  ------------------------------------------------------------
AqueK685_Aque_STKR2  ------------------------------------------------------------
AqueK686_Aque_STKR2  ------------------------------------------------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ------------------------------------------------------------
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     ------------------------------------------------------------
daf-1_Cele_STKR1     ---GVTV------------QDRKILGPQKPKDESPA------------------------
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ------------------------------------------------------------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ------------------------------------------------------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    ------------------------------------------------------------
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     ------------------------------------------------------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  IFRGVNLNDTKAAAECGSYENL-KYHPYNFE-DFGSTLVLLWNLMIVNNWHVIVDAYVRR
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  ------------------------------------------------------------
AqueK685_Aque_STKR2  ------------------------------------------------------------
AqueK686_Aque_STKR2  --------------------------P--------K------------------------


TGFbR2_Hsap_STKR2    ------------------------------------------------------------
TGFbR1_Hsap_STKR1    ------------------------------------------------------------
MISR2_Hsap_STKR2     ------------------------------------------------------------
MISR2_Mmus_STKR2     ------------------------------------------------------------
BMPR2_Mmus_STKR2     ------------------------------------------------------------
BMPR1B_Mmus_STKR1    ------------------------------------------------------------
BMPR1A_Mmus_STKR1    ------------------------------------------------------------
ALK7_Mmus_STKR1      ------------------------------------------------------------
ALK4_Mmus_STKR1      ------------------------------------------------------------
ALK2_Mmus_STKR1      ------------------------------------------------------------
ALK1_Mmus_STKR1      ------------------------------------------------------------
ACTR2B_Mmus_STKR2    ------------------------------------------------------------
ACTR2_Mmus_STKR2     ------------------------------------------------------------
daf-4_Cele_STKR2     ------------------------------------------------------------
daf-1_Cele_STKR1     --------------------NG------------APRIVQKEIDRED---EQENWR----
BMPR1A_Hsap_STKR1    ------------------------------------------------------------
BMPR1B_Hsap_STKR1    ------------------------------------------------------------
BMPR2_Hsap_STKR2     ------------------------------------------------------------
ALK7_Hsap_STKR1      ------------------------------------------------------------
ALK4_Hsap_STKR1      ------------------------------------------------------------
tkv_Dmel_STKR1       ------------------------------------------------------------
put_Dmel_STKR2       ------------------------------------------------------------
SAX_Dmel_STKR1       ------------------------------------------------------------
wit_Dmel_STKR2       ------------------------------------------LSL---------------
BABO_Dmel_STKR1      ------------------------------------------------------------
TGFBR1_Mmus_STKR1    ------------------------------------------------------------
TGFBR2_Mmus_STKR2    ------------------------------------------------------------
sma-6_Cele_STKR1     ------------------------------------------------------------
ALK2_Hsap_STKR1      ------------------------------------------------------------
ALK1_Hsap_STKR1      ------------------------------------------------------------
ACTR2B_Hsap_STKR2    ------------------------------------------------------------
ACTR2_Hsap_STKR2     ------------------------------------------------------------
TGFbR1_Spur_STKR1    --------------------------------------MQNTCD-ASQ--SGDDLKGRL-
ALK2_Spur_STKR1      ------------------------------------------------------------
BMPR1_Spur_STKR1     ------------------------------------------------------------
TGFbRII_Spur_STKR2   ------------------------------------------------------------
ACTR2_Spur_STKR2     ------------------------------------------------------------
BMPR2_Spur_STKR2     ------------------------------------------------------------
AqueK680_Aque_STKR1  ------------------------------------------------------------
AqueK681_Aque_STKR1  TSIYSRIYFVIWWVLSETVINGILLGYLIEILSITTIRLKDVFKDFNNKSKREKLA--LV
AqueK682_Aque_STKR1  ------------------------------------------------------------
AqueK683_Aque_STKR2  ------------------------------------------------------------
AqueK684_Aque_STKR2  ------------------------------------------------------------
AqueK685_Aque_STKR2  ------------------------------------------------------------
AqueK686_Aque_STKR2  ------------------------------------------------------------


TGFbR2_Hsap_STKR2    ------------------------------E-KIPEDGSLNTTK
TGFbR1_Hsap_STKR1    ----------------------------------------GIKM
MISR2_Hsap_STKR2     -----------------------------------QPACTLSPV
MISR2_Mmus_STKR2     --------------------------------PVGDTVQVYVNE
BMPR2_Mmus_STKR2     --------------------------------TTVSKDIGMNCL
BMPR1B_Mmus_STKR1    ----------------------------------------DIKL
BMPR1A_Mmus_STKR1    ----------------------------------------DVKI
ALK7_Mmus_STKR1      ----------------------------------------DCKA
ALK4_Mmus_STKR1      ----------------------------------------DVKI
ALK2_Mmus_STKR1      --------------------------------------KLKTDC
ALK1_Mmus_STKR1      --------------------------------------KPKVIH
ACTR2B_Mmus_STKR2    ------------------------------T-NV-DLLPKESSI
ACTR2_Mmus_STKR2     ------------------------------T-NV-DFPPKESSL
daf-4_Cele_STKR2     ------------------------------T-PTPSGTFGTFTT
daf-1_Cele_STKR1     --------------------ETAKTP-NGHI-SSNDDSSRPLLG
BMPR1A_Hsap_STKR1    ----------------------------------------DVKI
BMPR1B_Hsap_STKR1    ----------------------------------------DIKL
BMPR2_Hsap_STKR2     --------------------------------TMVSKDIGMNCL
ALK7_Hsap_STKR1      ----------------------------------------DCKA
ALK4_Hsap_STKR1      ----------------------------------------DVKI
tkv_Dmel_STKR1       --------------------------------------VPIKIV
put_Dmel_STKR2       ------------------------------T-NIDDAKESTNCL
SAX_Dmel_STKR1       ------------------------------------LDFDEVCV
wit_Dmel_STKR2       ------------------------------YDDRMMDSSLLNIL
BABO_Dmel_STKR1      ----------------------------------------KVKN
TGFBR1_Mmus_STKR1    ----------------------------------------GIKM
TGFBR2_Mmus_STKR2    ------------------------------E-KIPEDGSLNTTK
sma-6_Cele_STKR1     ---------------------------------SGLVESATNQS
ALK2_Hsap_STKR1      --------------------------------------KLKTDC
ALK1_Hsap_STKR1      --------------------------------------KPKVIQ
ACTR2B_Hsap_STKR2    ------------------------------T-NV-DLPPKESSI
ACTR2_Hsap_STKR2     ------------------------------T-NV-DFPPKESSL
TGFbR1_Spur_STKR1    ------P-------------PSAIIP-T-SH-PPNVPNPYPILS
ALK2_Spur_STKR1      ----------------------------------DPYHWEKIIA
BMPR1_Spur_STKR1     ----------------------------------------EFKV
TGFbRII_Spur_STKR2   ------------------------------Y-TSKGKRGRTTLV
ACTR2_Spur_STKR2     -----------------------------RN-SP-SPPPKESNL
BMPR2_Spur_STKR2     --------------------------------AKLQANFELECV
AqueK680_Aque_STKR1  --------------------------------------RLDFDE
AqueK681_Aque_STKR1  CLFIFVPQDLREMFRGEADYEDLDAFHSWNI-FDATFKEKQGES
AqueK682_Aque_STKR1  -------------------------------------KEKIQNE
AqueK683_Aque_STKR2  ------------------------------M-SPGHVIIAETHL
AqueK684_Aque_STKR2  --------------------------------PDNEENPTETTL
AqueK685_Aque_STKR2  ---------------------------------VDVTTGQPKSH
AqueK686_Aque_STKR2  ----------------------------RLS-DAEHDDTTTSLS