Gene ULK_c (S.moellendorffii)

ULK_c

Species: S.moellendorffii
Alias: ULK_c
External Links:
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
ULK_c.AA Protein None 579 None Fasta, JSON
ULK_c.NA RNA None 1740 None Fasta, JSON
ULK_c.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of ULK_c.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ULK_c.AA ULK 14-269 34 8.99999999999e-110 370.98 In-house 1-324 (324) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-324/324
Sequence Identity: 34% (112 aa)

YITSQEIGAGSFA-VVWKARHKIT---GHEVAIKEIGTEKLNKKLQE--------SLLSEISILKKAN---HPN--IIRLHAIVEAPDR--IYLILEYCA
|. ....| |||. .| |.|.|.|   .  ||.| |   |.||| .|        .| .||.|.|| .   |||  |..|. . | ..   ||.|.||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLAGYIHRHGKVGESA----------ARNIMQQLGSGLQVLRKNNLIHRDLKPQNLLLSTNDH---------NAVLKIADFGFARSLQPQGMAETLC-
||||  ||....| .|            |.....|. .|.. |.|.| ||||.||||.|.. ...         | ||||||||||....  .|....| 
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GSPLYMAPEILH----CQKYD-AKADLWSVGAILYQLVLGRPPFSGN--NHV----QLLQN-------ITKNEVQFP---HAAQLHPDCID
         |.||||||.||.    ...|. .|.|.||.| |.|... |..||...  . .    .|..|       | .. .|||    . .. |.|.|
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

MCRKLLRRNPVERLSFEEFFNHPFM
  |..| ... .| |.||.||||..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase ULK_c.AA ULK 14-269 35 4.5e-109 368.67 In-house 1-329 (329) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-329/329
Sequence Identity: 35% (116 aa)

YITSQEIGAGSFAVVWKARHKIT----GHEVAIKEIGTEKLNKKLQE--------SLLSEISILKKAN--------HPNIIRLHAIVEAPDR--IYLILE
|. ....| |||..| |.|.|.|    .  ||.| |  .|.|.|..|        .| .|| |.|| .        ||||..|. . | ..   ||.|.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCAGGDLAGYIHRHGKVGESA----------ARNIMQQLGSGLQVLRKNNLIHRDLKPQNLLLSTNDH---------NAVLKIADFGFARSLQPQ-----
|| ||||  ||....| .|.           |.....|. .|.. |.|.| ||||.|||| |.. ...         | ||||||||||....       
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-GMAET----LCGSPLYMAPEILH----CQKYD-AKADLWSVGAILYQLVLGRPPFSGN-NH-V-----QLLQN-------ITKNEVQFP---HAAQLHP
  |. .    |||.||||||.||.    ...|. .|.|.||.| |.|... |.|||... |  .     .|..|       | |.  |||    . |. |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

DCIDMCRKLLRRNPVERLSFEEFFNHPFM
.|.|  |..| ... .| |.||.||||..
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase ULK_c.AA S_TKc 14-269 36 5.6e-102 346.01 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-231/231
Sequence Identity: 36% (99 aa)

YITSQEIGAGSFAVVWKARHKITGHEVAIKEIGTEKLNKKLQESLLSEISILKKANHPNIIRLHAIVEAPDRIYLILEYCAG--GDLAGYIHRHGK----
|   ..|| |.|..|.|.||| ||..||||.|          |....||.|||| .||||..|. . .  |..|...||| |  |||  ||...|.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--VGESAARNIMQQLGSGLQVLRKNNLIHRDLKPQNLLLSTNDHNAVLKIADFGFARSLQPQGMAETLCGSPLYMAPEILHCQKYDA-KADLWSVGAILY
    |  || .|.|. ..|. . ... |||||||.|.||..     ..||.|||.|| |       |.||.| |||||.|   .|.  |.| ||.| |||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

QLVLGRPPFSGNNHVQLLQNITKNEVQFPHAAQLHPDCIDMCRKLLRRNPVERLSFEEFFN-------HPFM
 .. |.|||.  .. .....|              |...|. ||.|...| .|..  | ..       ||..
EMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ULK_c.AA Pkinase 14-269 34 7.6e-96 329.52 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-293/293
Sequence Identity: 34% (102 aa)

YITSQEIGAGSFAVVWKARHKITGHEVAIKEIGTEKLNKKLQESLLS--EISILKKANHPNIIRLHAIVEAPDRIYLILEYCAGG----DLAGYIH--RH
| . . ||.|||..|.|..|| ||..||.|.|  .. ... .....   ||.|.|. |||||.||. ..| .|.||...||| ||    ||. ||.  ||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKV--GESAARNIMQQLGSGLQVLRKNNLIHRDLKPQNLLLSTNDHN-AVLKIADFGFARS--LQPQGMAETLCGSPLYMAPEILH-CQKYDAKADLWSV
|..   |  ....| |. .||. . ... |||||||.|.|.. |.|. | .||.|||.|.   . ... . |.||.| |||||..  .|.|. |.| ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GAILYQLVLGRPPFSGN------NHVQLLQNITKNEVQFPHAAQ-------------------LHPDCIDMCRKLLRRNPVERLSFEEFFNHPFM
| |||....|||||.|       .. |....| . .. |.                       ....|.| ....|...| .|...|. ..||..
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase ULK_c.AA CAMK 19-269 25 1.3e-95 308.51 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-269
Range on HMM: 1-425/425
Sequence Identity: 25% (108 aa)

EIGAGSFAVVWKARHKITG------------HEVAIKEIGTEKLNKK--------------------------LQESLLSEISILKK-------ANHPNI
..| |||..| ...|| |.            ..|||| | ..|| .|                           ......||.|.||        .||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLHAIVE------------APDR--------IYLIL---EYCAGG----DLAGYIHRH---------------GKVGESAARNIMQQLGSGLQVLRKNN
|.|. . |              ..        .|...   ||| ||    ||  || .|               |.. |. || ...|. |... . ..|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

LIHRDLKPQNLLLSTNDHN--------------AVLKIADFGFARSLQPQG------------------------MAETLCGSPLYMA-PEIL----HCQ
 .|||||| |.||..|. .              . .||.|||||. ..|                          . .| ||.| ||| ||.|    ||.
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

K----------YDAKADLWSVGAILYQLVLGRPPFSGN-------------NHVQLLQNITKNEVQFPHAA----------------------QLHPDCI
.          |. |.| ||.| ||| .. |.||| |              |  .|...|.| . .||.                        .. ..|.
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DMCRKLLRRNPVERLSFEEFFNHPFM
|. ||.|...| .|.. |.  |||.|
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase ULK_c.AA AGC 14-269 23 1.3e-93 241.75 In-house 1-395 (395) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-395/395
Sequence Identity: 23% (94 aa)

YITSQEIGAGSFAVVWKARHK------ITGHEVAIKEIG-TE---KLNKKLQESLLSE------------ISILKKAN----------HPNIIR-LHAIV
.     || |||  |. .|.|       ||.  |.| .   .   ...|. .|  ..|              ||.|.|          ||.|.. ||   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EAPDR--IYLILEYCA---------GG-DLAGYIH---RHGKVGESAARNIMQQ---LGSG-----LQVLRK-NNLIHRD-LKPQNLLLSTNDHNAVLKI
. .|.  .|...||.          || .|  ...   . |.  |..|| .. .   . .|     |. | . .. |||| ||| |.||  .     .|.
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKI-CGCIVLALEYLHSHMGIIHRDYLKPENILLDED---GHIKL

ADFGFARSLQPQG---------------------------------------------------MAETLCG--SPLYMAPEILHCQKYDAKADLWS--VG
.|||..  .   |                                                   .. |.||  .| |||||||    |.  .| ||  .|
TDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLG

AILYQLVLGRPPFSGNNHV----------QLLQNIT------KNEVQFPHA--------AQLHPDCIDMCRKLLRRNPVERLS----------FEEFFNH
...|... |.|||.|.| .          .. |.|       ...|.||.          .. |.. | ..||| ..| .||           .||  ||
CLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNH

PFM
|. 
PWF
Kinase ULK_c.AA CAMKL 14-269 34 7.7e-89 283.63 In-house 1-297 (297) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-297/297
Sequence Identity: 34% (105 aa)

YITSQEIGAGSFAVVWKARH-KITGHEVAIKEIGTEKLNKKLQES-------------LLSEISILKKAN---HPNIIRLHAIVEAPDR------IYLIL
|.  ...| |||..|  |.| ..||..|||| |  .|.... . .             .  ||.|.|. |   |||||.|. ..| |.       |||..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCAGGD--LAGYIHRH----GKVGESAARNIMQQLGSGLQVLRKNNLIHRDLKPQNLLLSTNDHNAVLKIADFGFARSLQP-----QGMAETLCGSPLY
||| ||.  |  || .|    |.  |. || . .|. |... . ... .|||.|| |.||. |. | ..||.||||.   .|       . .| |||| |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

MAPEILHC--QKYD-AKADLWSVGAILYQLVLGRPPFS-------GNNHVQLLQNITKNEVQFPHAA-QLHPDCIDMCRKLLRRNPVERLSFEEFFNHPF
|||||.    ..||  |.| || | ||| .| |. ||        |.... .| ....    .|    ..  ||.|. ||.| .|| .| . ..  |||.
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

M
|
M
Kinase ULK_c.AA Ciliate-E2a 14-269 34 6.1e-88 258.94 In-house 1-275 (275) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-275/275
Sequence Identity: 34% (95 aa)

YITSQEIGAGSFAVVWKARHKITGHEVAIKEIGTEKLNKKL--QESLLSEISILKKANHPNIIRLHAIVEAPDRIYLILEYCAGGDLAGYIHRHGKVGES
| .  .|| |.|..| .|.||.|| . |.| .   |.. .   .|..  ||.|... .|||||.|. . |  . .||..||| ||.|  .|  ...  | 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--AARNIMQQLGS-GLQVLRKNNLIHRDLKPQNLLLS---TND-HNAVLKIADFGFARSL--QPQGMAETLCGSPLYMAPEILHCQK------YDAKADL
   .. ||||| . ||. . ..| .||||||.|.|.    .|.  |. .||.|||.|.      .    . ||.| |.|||.|          || | |.
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WSVGAILYQLVLGRPPFSGNNHVQLLQNITKNEVQFPHAA---QLHPDCIDMCRKLLRRNPVERLSFEEFFNHPFM
||.|.|.| |. |.||| | .. . ||.. | . .|       ..  .|.|. .|.|  .| .|.. ..  |||..
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase ULK_c.AA CAMK1 14-269 36 8.5e-83 240.5 In-house 1-276 (276) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-276/276
Sequence Identity: 36% (100 aa)

YITSQEIGAGSFAVVWKARHKIT---GHEVAIKEIG-TEKLNK----KLQESLLSEISILKK---ANHPNIIRLHAIVEAPDRIYLILEYCAGGDLAGYI
|.   |||.|.|..| .. || |   |...||| |   . . |    | ||.|. ||.|.||    .||||| .. . | .. .||..|.. ||.|   |
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRI

HRHGKVGESAARNIMQQLGSGLQVLRKNNLIHRDLKPQNLLLSTNDHNAVLK--IADFGFARSLQPQG-MAETLCGSPLYMAPEILHC---QKYDAKADL
   |.  |  ||.||.|. | .. . ...  ||||||.|||....| .. .|  ||||| .. . ..  . .| ||.| |.|||.| |   . || . |.
VEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDM

WSVGAILYQLVLGRPPFSGNN-HVQLLQNITKNEVQFPHAAQLH--PD-CIDMCRKLLRRNPVERLSFEEFFNHPFM
||.| |.| |  | ||| ..| . .|.. |.| |. ||   . .       |  ...|  .| .|...|.. |||. 
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase ULK_c.AA Ciliate-E2 14-269 24 4.7e-82 278.91 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-365/365
Sequence Identity: 24% (94 aa)

YITSQEIGAGSFAVVWKARHKITGH------------------EVAIKEIGTEKLNKKLQESLLSEISILKKAN----------------HPNIIRLHAI
|.  . || |.|..|.|.... ...                  .|.||..  . ..|.  |....||.|... |                |||||...  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VE--APDRIYLILEYCAGGDLAGYIH------------RHGKVGESAARNIMQQLGS---------------GLQVLRKNN-LIHRDLKPQNLLLSTNDH
 .    . |||..||| ||||  ||               ..  |  ...||.|. .               .|. | ..|  ||||.||.|.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

NAVLKIADFGFARSLQPQ--------------------------------GMAETLCGSPLYMAPEILHCQK---------YDAKADLWSVGAILYQLVL
   .||.|||... ....                                 |. |.||.| |||||||  .|         || |.|.||.| |||... 
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GRPPFSGNNHVQLLQNITKNEVQFP----------------HAAQLHPDCIDMCRK----LLRRNPVERLS-FEEFFNHPFM
|.|||        .|.| .....||                   .. ..|.|...|    .| ..| .|.. .|. .|||..
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase ULK_c.AA MARK 14-269 39 3.1e-79 258.65 In-house 1-262 (262) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-262/262
Sequence Identity: 39% (106 aa)

YITSQEIGAGSFAVVWKARHKITGHEVAIKEIGTEKLNK-KLQESLLSEISILKKANHPNIIRLHAIVE--APDR-IYLILEYCAGGDLAGYIHRH--GK
|   ..|| ||.|.| .|.|| || .|||| .  .|||. .  ... .||.|.|| .|||||.|. ..|   . . ||||.||. ||.| .||  |  |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

VGESAARNIMQQLGSGLQVLRKNNLIHRDLKPQNLLLSTNDHNA--VLKIADFGFARSLQPQGMAETLCGSPLYMAPEILHCQKYD-AKADLWSVGAILY
  |. || | .|. |... . ..| .|||.||.|.|.   |.|     ||.||||..  .|  . .| ||.| ||||||.  ..||  |.| || | .||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILI---DENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLY

QLVLGRPPFSGNN--HVQLLQNITKNEVQFPHAAQLHPDCIDMCRKLLRRNPVERLSFEEFFNHPFM
 .| |. || | .   ..| ..|.. . ..|.   . ..| .. ..||  || || . ||  .||.|
FMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase ULK_c.AA Ciliate-E2-Unclassified 14-269 27 1.7e-75 257.11 In-house 1-352 (352) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-352/352
Sequence Identity: 27% (99 aa)

YITSQEIGAGSFAVVWKARHKITGHEV-----AI-------KEIGTEKLNKKLQESLLSEIS-------------ILKKANHPNIIRLHAIVEAPDRIYL
|.  . || |.|..|.|..|| .. ..     ..       | | ... ......  . ...             ||.  .||.|.... . .  . ||.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ILEYCAGGDLAGYIHRHGK-----------------VGESAAR-----NIMQQLGSGLQVLRKNN-LIHRDLKPQNLLLSTNDHNAVLKIADFGFARSLQ
..||| ||||  ||   .|                 . | .|.     ... |. .||. | ..|  ||||.||.|.|.. |  |  .||.|||... .|
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------PQGMAETLCGSPLYM----APEILHCQKYD----AKADLWSVGAILYQLVLGRPPFSGNNHVQ----------------LLQNI
                .| |. | ||.| ||    |||.|  |.||     |.| ||.| |||... |..||..||  |                |.|||
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

TKNEVQFPHAA------QLHPDCIDMCR----KLLRRNPVERLSFEEFFNHPFM
 ....|||..       ...| ..|...    |.|  || .|..||. .|||..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase ULK_c.AA Pkinase_Tyr 14-198 30 9.5e-30 101.38 Pfam 1-199 (270) Show / Hide 
Range on Protein: 14-198
Range on HMM: 1-199/270
Sequence Identity: 30% (61 aa)

YITSQEIGAGSFAVVWKARHK----ITGHEVAIKEIGTEKLNKKL--QESLLSEISILKKA-NHPNIIRLHAIVE-APDR--IYLILEYCAGGDLAGYIH
 .  ...|.|.| .|.|.. |     |. .||.| .  |.  ..   .|....|..|.|.  .||||.||....    .   ||...||...|||  | .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RH----GKVGESAARNIMQQLGSGLQVLRKNNLIHRDLKPQNLLLSTNDHNAVLKIADFGFARSLQPQGMA-ETLCGSPL---YMAPEILHCQKYDAKAD
.|    ...  .   .. .|  .|.. |  .|.|||||   | |..    | | ||.||| || ... .    .  |..|    |||| ..  |.  | |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

LWS
 ||
VWS
Kinase ULK_c.AA TyrKc 14-269 21 1.9e-20 75.15 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-269
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

YITSQEIGAGSFAVVWKARHKITGHEVAIKEIGTEKLNKKLQESLLSEISILKKA--NHPNIIRLHAIVEAP-------DRIYLILEYCAGGDLAGYIHR
    ...| | | .|.|.. |    .||.| .  ..     .| ...|..|..|   .||||.||....  .       . .....||...|||  |...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HGK-VGESAARNIMQQLGSGLQVLRKNNLIHRDLKPQNLLLSTNDHNAVLKIADFGFARSLQPQ-------GMAET----LCG--SPL-YMAPEILHCQK
|.. .  .   ... |  .| . | ..|.|||||   | |.. |    . ||.||| .| .           .  .     .    |.  |||| .   |
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YDAKADLWSVGAILYQLV-LGRPPFSG-----NNHVQLLQNITKNEVQFPHAA-------QLHPDCIDMCRKLLRRNPVERLSFEEFFNHPFM
.  | | || |  .. .  .| .| .|      .  ...... . .   . .          ...  .. ..  ...| .| .|.|   | ..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF