Gene CK2-1 (S.moellendorffii)

CK2-1

Species: S.moellendorffii
Alias: CK2-1
External Links:
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
CK2-1.AA Protein None 410 None Fasta, JSON
CK2-1.NA RNA None 1233 None Fasta, JSON
CK2-1.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of CK2-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CK2-1.AA CK2 112-397 76 1.4e-231 699.83 In-house 1-288 (288) Show / Hide 
Range on Protein: 112-397
Range on HMM: 1-288/288
Sequence Identity: 76% (219 aa)

YEVVRKVGRGKYSEVFEGINCVNNEHC--IIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQQSKTPSLIFEYVNNTDFKTLYPTLTDYDIRYY
|||.||.|||||||||||||  |||.|  .|||||||||||||||||||.||.|||||.||.|||.|..||.|.|.|||||||||..||.||||||||||
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

LYELLKALDHCHSQGIMHRDVKPHNVMIDHEQRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGH
..||||||| |||.|||||||||||.|||||.|||||||||||||||||..|||||||||.|||||||| |.|||||||||||||||.|||.||||| ||
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH

DNHDQLVKIAKVLGTDELNAYLNKYHLELDAHFESMVGRHSRKPWSKFINNDNQHLVNPEALDFLDKLLRYDHQERLTAREAMAHAYF
|| ||||||.|||||..| .||.||...|| .|......|..|||..||...|.||..|||.|||||.||||||||.||.||| |.||
DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase CK2-1.AA CMGC 112-397 21 3.1e-101 333.48 In-house 1-513 (513) Show / Hide 
Range on Protein: 112-397
Range on HMM: 1-513/513
Sequence Identity: 21% (109 aa)

YEVVRKVGRGKYSEVFEGIN--------------CVNNEHCIIKILKPVKKKKIK---------------REIKILQNLC----------------GGPN
||...|.|.| |..|.....              . .||.. ||..| .. ...                ||||||..|                   .|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVKLLDIVRDQQSKTP---------------SLIFEYVNNTDFKTLYP-----------TLTDYD------------IRYYL------YELLKALD--HC
||||.||... .|...                |.|||. .. .. ..             |..              |.|..      | .|..|.  .|
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSQG--IMHRDVKPHNVMIDHEQRK-------------------LRLIDWGLAEFYHPG----------------------KEYNVRVASRYFKGPELLV
||..  |.||| || |..|.|. .                    |...|.||| .|||                       . |  .|..|. . ||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

DLQDYD---------YSLDMWSLGCMFAGM-------IFRKEPFFYGHDN-----------HDQLVKIAKVLG------------------TDELNAYLN
  ..|.         .. ||||.||.|| |       |||..|.| ||..            ||| || ||||                  ..|   ...
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

KY-----------------HLELDAHFESM---VGRHSRKPWSKFINNDNQ------------------------------HLVNPEALDFLDKLLRYDH
..                 . |   .. ..    ... .|||.... ...                               .. .|.|.|.|.|.|.||.
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

QERLTAREAMAHAYF
..|.|| .|..| ||
DKRITAEQALQHPYF
Kinase CK2-1.AA Pkinase 112-397 25 1.7e-80 278.57 Pfam 1-293 (293) Show / Hide 
Range on Protein: 112-397
Range on HMM: 1-293/293
Sequence Identity: 25% (80 aa)

YEVVRKVGRGKYSEVFEGINCVNNEHCIIKILKPVKKKKIKR-------EIKILQNLCGGPNIVKLLDIVRDQQSKTPSLIFEYVNNT----DFK---T-
|...||.|.| ...|.....  ...   .||.| ...|. |.       ||.|...| . ||||.|.|...|  .. . ...||....    | .   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

-LYPTL--TDYDIRYYLYELLKALDHCHSQGIMHRDVKPHNVMIDHEQRK---LRLIDWGLAEF--YHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDM
  . ..  .. ... |.|..|..|..|||.||.|||.|| |..||..      ....|.|||..  | ..  ..... ....  ||.. . |.|... ||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGCMFAGMIFRKEPFFYGH----DNHDQLVKIAKVLGTDELNAYLNKYHLELDAHFESMVGRHSRKPWSKFINNDNQHLVNPEALDFLDKLLRYDHQE
||.||... |.... ||  ||    . |||...|....|..    . ...   ..  |     .        | .  . |....|..||....|..| ..
WSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--------F-HWTF-HNWSEECKDFIKWCLCKDPKK

RLTAREAMAHAYF
|.||.... | .|
RPTAEQILQHPWF
Kinase CK2-1.AA S_TKc 112-397 25 3.2e-75 257.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 112-397
Range on HMM: 1-231/231
Sequence Identity: 25% (79 aa)

YEVVRKVGRGKYSEVFEGINCVNNEHCIIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQQSKTPSLIFEYVNN--TDFKTLYPT---------
||..||.|.| ...|. ...   .... |||.|    ..|.|||.||..  . ||||||.|. .|   .   ...||...   | ...            
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LTDYDIRYYLYELLKALDHCHSQGIMHRDVKPHNVMIDHEQRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDY-SLDMWSLGCMFAGMI
..  ..|.|.|....||..|||.||.|||.|| |...|.    . ..| ||| ..      .  . ....  ||.|     |.. . |.||.||... |.
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

FRKEPFFYGHDNHDQLVKIAKVLGTDELNAYLNKYHLELDAHFESMVGRHSRKPWSKFINNDNQHLVNPEALDFLDKLLRYDHQERLTAREAMA------
 .. ||        |. .. |..|                                            |||.||..|.|..| ..|.|| ||..      
CGYPPFP-------QMQMMFKKIG-------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-HAYF
 | .|
CHPWF
Kinase CK2-1.AA CDK 112-397 26 6.7e-59 187.01 In-house 1-284 (284) Show / Hide 
Range on Protein: 112-397
Range on HMM: 1-284/284
Sequence Identity: 26% (87 aa)

YEVVRKVGRGKYSEVFEGINCVNN-----EHCIIKILK-PV-----KKKKIK----REIKILQNLCGGPNIVKLLDIVRDQQS---------KTPSLIFE
|| . |.|.| | .|. ...  ..     . . .| ..        .|  .     |||..|..|   ||||||.|.. . ..         .. ...||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

YVNNT-----DFKTLYPTLTDYDIRYYLYELLKALDHCHSQGIMHRDVKPHNVMIDHEQR----KLRLIDWGLAEFYH-------PGKEYNVRVASRYFK
|.        |            |. |.. ||..|..|||..||||| || | .|..       .| . | |||  ..       | ..|  .|  .   
YMDHDLKKYMD------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYR

GPELLVDLQDYD--YSLDMWSLGCMFAGMIF--RKEPFFYGHDNHDQLVKIAKVLGT--DELNAYLNKYHLELDAHFESMVGRHSRKPWSKFINNDNQHL
 ||||   ..|.   . ||||.|| || |.    ..|.| |   .||| || ...||  ..    . |. .                             
APELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY----------------------------

VNPEALDFLDKLLRYDHQERLTAREAMAHAYF
      |.|.|.| || . |..| .|. | ||
------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CK2-1.AA CDC2 112-397 30 1.9e-47 143.61 In-house 1-301 (301) Show / Hide 
Range on Protein: 112-397
Range on HMM: 1-301/301
Sequence Identity: 30% (95 aa)

YEVVRKVGRGKYSEVFEGINCVNNEHCIIKILKPVKKKKIK--------REIKILQNLCGGPNIVKLLDIVRDQQSKTPSLIFEYVNNTDFKTLYP----
|. ..|.| | | .|. ...   |. . .|  . ..             ||| .|..|   |||||| |..     .   ..|||. . | | .      
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIR-LEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYL-DMDLKKYMDMSIP

---TLTDYDIRYYLYELLKALDHCHSQGIMHRDVKPHNVMIDHEQRKLRLIDWGLA-EFYHPGKEYN--VRVASRYFKGPELLVDLQDYDYSLDMWSLGC
    ..   .. |.| .|.....||...||||| || |  || . . ... | |||  |  | ..|     |  .    ||.|   ..|. . ||||.||
KNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGC

MFAGM-IF-RKEPFFYGHDNHDQLVKIAKVLGTDELNAYLNKYHLELDAHFESMVGRHSRKPWSKFINN----DNQHLVNPEALDFLDKLLRYDHQERLT
 || | .   |.|.| |    ||| || ..|||   . . . . |    .. .  .|  ..  || . |     ||  ..||..| |...|.|| | |..
IFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLP---DYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRIS

AREAMAHAYF
|.||..| ||
AKEALQHPYF
Kinase CK2-1.AA CAMK 117-294 17 3.4e-47 149.71 In-house 1-323 (425) Show / Hide 
Range on Protein: 117-294
Range on HMM: 1-323/425
Sequence Identity: 17% (58 aa)

KVGRGKYSEVFEGINCVNN------------EHCIIKILK-------------------------------PVKKKKIKREIKILQNLCG------GPNI
. ||| ...|...|.  ..            ... |||..                               |...|...|||.|...| |       |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLLDIVRDQQSK-------TPS-----------LIF---EYVNNT----D-FKTLY-----------------PTLTDYDIRYYLYELLKALDHCHSQG
.||...  | .         | |           ...   ||. .     | |  .                    .|  . |.|   .. |...|||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IMHRDVKPHNVMIDHEQ----------------RKLRLIDWGLAEFYHP------------------------GKEYNVRVASRYFKG-PELLVD-----
|.||| || |...|.                   .. .||.|.| .. |                        |. .. .. . ..   ||.|       
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------LQDYDYSLDMWSLGCM
         . |... ||||.|..
MQNATDEEKPYYGPKCDMWSCGVI
Kinase CK2-1.AA Ciliate-E2 112-397 16 1.5e-43 147.4 In-house 1-365 (365) Show / Hide 
Range on Protein: 112-397
Range on HMM: 1-365/365
Sequence Identity: 16% (71 aa)

YEVVRKVGRGKYSEVFEG--INC---------------------VNNEHCIIKILKPVKKKKIKREIKILQ---------N------LCGGPNIVKLLDI
|....| |.| .. |...  ..                      |..    .||.|. ... ||.||.|..         |      .   |||.|. . 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VRDQQSKTPSLIFEYVNNTDFKT---------------LYPTLTDYDIRYYLYELLK---------------ALDHCHSQG-IMHRDVKPHNVMIDHEQR
  ... ..  |..||..  | .                    .|.. |.|. ...|.               || ..||.. |.||| || |...     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

KLRLIDWGLAEFYHPG----------KEYNVRVA-----------------------SRYFKGPELLVDLQD--------YDYSLDMWSLGCMFAGMIFR
 . .||.||. .|..           |.|                            . ... || |   ..        |||. |.||||...  |.| 
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

KEPFFYGHDNHDQLVKIAKVLGTDELNAYLNKYHLELDAHFESMVGRHSRKPWSKFINNDNQ------------------------HLVNPEALDFLDK-
| ||                                                    ...  |                        . . .|. |.. | 
KPPF----------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKF

---LLRYDHQERLT-AREAMAHAYF
   .| .| ..|.| . ... | .|
GKRMLQKDPEKRITGWEQILNHPWF
Kinase CK2-1.AA RCK 112-324 29 1.2e-33 103.89 In-house 1-232 (298) Show / Hide 
Range on Protein: 112-324
Range on HMM: 1-232/298
Sequence Identity: 29% (70 aa)

YEVVRKVGRGKYSEVFEGINCVNNEHCIIKILKPVKKKKIK-----REIKILQNLCGGPNIVKLLDIVRDQQSKTPSLIFEYVNNTDFKTLYP-----T-
| .....|.| |..|....|  ..|   || .|  | ....     |||| |  |   |||.||....||. . . ...|||. .  .. .       . 
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK-QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKY

LTDYD--IRYYLYELLKALDHCHSQGIMHRDVKPHNVMIDHE--------QRKLRLIDWGLA-EFY--HPGKEYNVRVASRYFKGPELLVDLQDYDYSLD
|.     |. ..| .|..|.|.|..|..|||.|| | |.  .        |  . ..| ||. |..  .|  .|   | .|.   ||.|   . |.. .|
LPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDY---VSTRWYRAPECLLRCTYYNSPMD

MWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGT
.|..|| ..  .  . | | | .  ||. || ||.||
IWAVGCIMYE-LYMLRPLFPGSSEIDQIFKICKVMGT
Kinase CK2-1.AA CDK5 112-324 33 8.6e-32 97.36 In-house 1-218 (287) Show / Hide 
Range on Protein: 112-324
Range on HMM: 1-218/287
Sequence Identity: 33% (75 aa)

YEVVRKVGRGKYSEVFEGINCVNNEHCIIKILKPVKK-----KKIKREIKILQNLCGGPNIVKLLDIVRDQQSKTPSLIFEYVNNTDFKTLYPTLTDY--
|| . |.| | |  |. . |    |   .|  .             ||| .|. |   .||| | |..   .  |  |.||.. . | |     ....  
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELK-HKNIVRLHDVIHSEKKLT--LVFEFCDQ-DLKKYMDSCNGEMD

--DIRYYLYELLKALDHCHSQGIMHRDVKPHNVMIDHEQRKLRLIDWGLAE-FYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFR
   |....| ||| |  ||.. ..||| || | .|  .  .|.| | |||  |  | . |   |    .  |  |   . |  | |||| || || |.  
MHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNG-ELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANA

KEPFFYGHDNHDQLVKIAKVLGT
  | | | | .||| .| |..||
GRPLFPGNDVEDQLKRIFKIMGT
Kinase CK2-1.AA GSK 267-397 28 2.8e-28 82.99 In-house 181-328 (328) Show / Hide 
Range on Protein: 267-397
Range on HMM: 181-328/328
Sequence Identity: 28% (45 aa)

SRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTDEL---NAYLNKY--HLELDAHFESMVGRHSRKPWSK-----
|||   |||. . ..|. . |.||.|| .| |. .. |.| |..  |||| |.|.|||.      .  ..|  .   .. |    .    .||.|     
SRYYRAPELIFGCTNYTCQIDVWSCGCVMAEMLKGQ-PLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKP----HPWQKNDTKY

--------------FINN---DNQHLVNPEALDFLDKLLRYDHQERLTAREAMAHAYF
              ....   |.|     ...|.. |.|.|| ..||...||.|| .|
EYQTYYHKKYRTVYMFKWCHTDMQ-----DWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase CK2-1.AA MAPK 265-397 36 1.8e-27 91.93 In-house 192-328 (328) Show / Hide 
Range on Protein: 265-397
Range on HMM: 192-328/328
Sequence Identity: 36% (51 aa)

VASRYFKGPELLVD--LQDYDYSLDMWSLGCMFAGMIF-RKEPFFYGHDNHDQLVKIAKVLGT--DELNAYLNKYHLELDAHFESM--VGRHSRKPWSKF
|| |.   ||..    ...|. . ||||.|| || |.  || |.| |.|  ||. .| .||||  .|.  .. .   .    ..|.    .. .|||.| 
VATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRK-PLFPGKDYIDQWNLIMEVLGTPSEEFIQCICM-SEHARNYIQSLGNLPKYPKKPWEKM

INNDNQHLVNPEALDFLDKLLRYDHQERLTAREAMAHAYF
. |.|  ..||.|.|.|.|.|  | ..|.|. ||..| ||
FPNANF-NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase CK2-1.AA GSK 112-250 25 1.2e-19 56.08 In-house 1-162 (328) Show / Hide 
Range on Protein: 112-250
Range on HMM: 1-162/328
Sequence Identity: 25% (42 aa)

YEVVRKVGRGKYSEVFEGINC----VNNEH----CIIKILKPVKKKKIKREIKILQNLC--GGPNIVKLLDIVRDQQSK-------TPSLIFEYVNNT--
||  ...|.|  . |......     ..|       ||   . |. |  || .|...|     ||||.|.     ...|         .|..||...|  
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY

----DFKTLYPTLTDYDIRYYLYELLKALDHCHSQGIMHRDVKPHNVMIDHEQRKLRLIDWG
    .. ..  ......|..| | ....| . || || |||.|| |. .|..  .| . | |
QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFG
Kinase CK2-1.AA MAPK 112-238 25 2e-11 35.54 In-house 1-151 (328) Show / Hide 
Range on Protein: 112-238
Range on HMM: 1-151/328
Sequence Identity: 25% (38 aa)

YEVVRKVGRGKYSEVFEGINCV------NNEHCIIKILK-----PVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQQ---SKTPS------LIFEYVNN
|. ....| | |  |.  |         ....  || .      |.  | . ||||.|. . . .||.||||| .  .    ....      ...|.   
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

TDFKTLY-PT-LTDYDIRYYLYELLKA--LDHCHSQGIMHRDVKPHNVMID
   . .. .  |.|  |.| .| .|..  | . || .. ||| || |. ..
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVN
Kinase CK2-1.AA CDK5 367-397 32 9.8e-11 29.65 In-house 257-287 (287) Show / Hide 
Range on Protein: 367-397
Range on HMM: 257-287/287
Sequence Identity: 32% (10 aa)

NPEALDFLDKLLRYDHQERLTAREAMAHAYF
. . .|.| |.|... ..|..| .|. |.||
DEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase CK2-1.AA RCK 367-397 35 5.1e-09 24.44 In-house 268-298 (298) Show / Hide 
Range on Protein: 367-397
Range on HMM: 268-298/298
Sequence Identity: 35% (11 aa)

NPEALDFLDKLLRYDHQERLTAREAMAHAYF
...... . |.|..| |.| || .|  | ||
SQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase CK2-1.AA CAMK 368-397 26 2e-08 22.54 In-house 396-425 (425) Show / Hide 
Range on Protein: 368-397
Range on HMM: 396-425/425
Sequence Identity: 26% (8 aa)

PEALDFLDKLLRYDHQERLTAREAMAHAYF
.|. |.. |.|..| ..|.|. ....|  .
QECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CK2-1.AA TyrKc 112-397 13 6.9e-08 -95.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 112-397
Range on HMM: 1-280/280
Sequence Identity: 13% (47 aa)

YEVVRKVGRGKYSEVFEGINCVNNEHCIIKILKPVKKKKIKREIKILQNL-CGGPNIVKLLDIVRDQ-----QSKTPSLIFEYVNNTDFKTLY----PTL
 .  .| |.| . ||..|.     . . .| ||. ... . ||..|. .|    ||||.|. ....|      .. . ...||. . | |       |.|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

TDYDIRYYLYELLKALDHCHSQGIMHRDVKPHNVMIDHEQRKLRLIDWGLAEFYHPG-------KEYNVRV--ASR------------------------
.  |  .. .   .  .. ||... |||    |.......   .  | ||. . . .       . | ..    ..                        
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

-----------------YF------KGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTDELNAYLNKYHLELDAHFESM
                 |       . .. .. . .  | ..    ..    |                                               
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MS----------------------------------------------

VGRHSRKPWSKFINNDNQHLVNPEALDFLDKLLRYDHQERLTAREAMAHAYF
           |          .|  .   .  ..|  .| | .|   | .|
-----------F------VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CK2-1.AA APH 210-257 31 0.000122 16.7 Pfam 159-207 (248) Show / Hide 
Range on Protein: 210-257
Range on HMM: 159-207/248
Sequence Identity: 31% (16 aa)

LYELLKALDHCHSQGIMHRDVKPHNVMIDHEQRKLR---LIDWGLAEFYHP
|.. |.|. .    ...|.|..|.|||.|  ... |   .|||. | . .|
LWAWLEAHWP--PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWGDP
Kinase CK2-1.AA Pkinase_Tyr 112-191 25 0.000272 15.16 Pfam 1-91 (270) Show / Hide 
Range on Protein: 112-191
Range on HMM: 1-91/270
Sequence Identity: 25% (23 aa)

YEVVRKVGRGKYSEVFEGINCV-----NNEHCIIKILKP---VK---KKKIKREIKILQNLCGGPNIVKLLDIVRDQQSK-TPSLIFEYVNN
 .  .| |.| . ||..|. .      .. .. .|.||.    .   ...  ||.||. .|.  ||||.|. .. ||.    . ...||. .
ITFGKKLGEGAFGEVYKGT-WKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH