Gene CRK7-p1_b (S.moellendorffii)

CRK7-p1_b

Species: S.moellendorffii
Alias: CRK7-p1_b
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7-plant1

Sequence

Name Sequence Type Origin Length Description Download
CRK7-p1_b.AA Protein None 541 None Fasta, JSON
CRK7-p1_b.NA RNA None 1626 None Fasta, JSON
CRK7-p1_b.kin_dom Protein Kinase Domain None 515 None Fasta, JSON

Protein domain

Protein domains of CRK7-p1_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CRK7-p1_b.AA CDK 26-343 45 3.1e-161 519.74 In-house 1-284 (284) Show / Hide 
Range on Protein: 26-343
Range on HMM: 1-284/284
Sequence Identity: 45% (155 aa)

FEKLEQIGEGTYGQVYMAREKDTN-----EIVALKKVRMDN-----EKEGFPITAIREIKILKKLQHENVIKLKEIVTSTGPEQDDPKETQKDAPKGAKE
.||||.|||||||.|| || |.|.     .||||||.||.|     |||||||||||||..||.| |.|..||......  .. .. |            
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDK----------

KSPSPPDGNIYKGSIYMVFEYMDHDLTGLSDRPGMRFTVPQIKCYMKQLLTGLYYCHINQVLHRDIKGSNLLIDNKGN-----LKLADFGLARSFSN--D
          .. ..||||||||||| .. |          |||||.||| ||.||| | ..|||.| .|.||.|.|.     ||.||||||| |..  .
----------HENKLYMVFEYMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQ

---QNAQLTNRVITLWYRPPELLLGCTKYG--PAVDMWSVGCIFAELLY---GKPVLTGKNEQDQLAKIFEFCGTPDETNWPGVSKLPWYNMHRPSIYYK
    |  .|..|.|||||.||||||...|.  ...|||||||||||..    .|| . |..|.||| |||..||||.| |||||.|||.|          
MSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY----------

RRVKDVFKQFDRHALDLVERMLTLDPLQASRIIAKDALDAEYF
               || ..||..|| .  || |..||. .||
---------------DLLNKMLCYDPKK--RISAEQALQHPYF
Kinase CRK7-p1_b.AA CDC2 26-343 40 9.1e-136 419.98 In-house 1-301 (301) Show / Hide 
Range on Protein: 26-343
Range on HMM: 1-301/301
Sequence Identity: 40% (137 aa)

FEKLEQIGEGTYGQVYMAREKDTNEIVALKKVRMDNEKEG--FPITAIREIKILKKLQ-HENVIKLKEIVTSTGPEQDDPKETQKDAPKGAKEKSPSPPD
..|.| ||||||| || .....||.||||||.| ..| ||  .| |||||| .||.|. |.|..||.... .                            
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ----------------------------

GNIYKGSIYMVFEYMDHDLTGLSD---RPGMRFTVPQIKCYMKQLLTGLYYCHINQVLHRDIKGSNLLIDNKGNLKLADFGLARSFSNDQNAQLTN-RVI
      ..||||||.|.||  . |    ..  ...  .| ||.|.| |. .|| ....|||.| .|.|||.|||.|.||||||| |.   .. .|.  |.
-----NKLYMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVV

TLWYRPPELLLGCTKYGPAVDMWSVGCIFAEL---LYGKPVLTGKNEQDQLAKIFEFCGTPDETNWPGVSKLPWYNMHRPSIYYKRRVKDVFKQ------
|||||.||.|||| .|  .|||||.||||||.      ||   |. | ||| |||.. |||.| .||||..|| |..  |  . .   ......      
TLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPR-WKPQDLSKICPNNQKKKN

---FDRHALDLVERMLTLDPLQASRIIAKDALDAEYF
    |  ..|| ..|| .|| .  || ||.||.  ||
QSCLDPEGIDLLMQMLQYDPQK--RISAKEALQHPYF
Kinase CRK7-p1_b.AA CMGC 26-343 26 7.6e-132 435.92 In-house 1-513 (513) Show / Hide 
Range on Protein: 26-343
Range on HMM: 1-513/513
Sequence Identity: 26% (141 aa)

FEKLEQIGEGTYGQVYMARE--------------KDTNEIVALKKVR---MDN------EKEGFPITAIREIKILKKLQ-----------------HENV
.|....|||||||.|| .|               ..||||||.||..   ...      ||.||||.|.|||||||.|.                 |.|.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

IKLKEIVTSTGPEQDDPKETQKDAPKGAKEKSPSPPDGNIYKG---SIYMVFEYMDHDLTGLSDRPG--------MRFTVPQ------------IKCYM-
.||..|... ... .... ...                 | .    ..|.||||||||| .. ..          | ..  .            ||..| 
VKLYDIFYHKNSDGNEYEDKHI-----------------I-SQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMI

-----KQLLTGLY--YCHINQ--VLHRDIKGSNLLIDNK--------------------GNLKLADFGLARSFSNDQ--------------------NAQ
     .|.|.||   ||| .   ..|||.| .|.||...                    |.||..||||||.... .                    | .
HIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRP

LTNRVITLWYRPPELLLGC---------TKYGPAVDMWSVGCIFAELLYG--------KPVLTGKNE-----------QDQLAKIFEFCGTPD-------
.|..| |.|||.||.|||.         ..|....|||||||||||.. |        ||   |..|           .|||.|||. .|||.       
YTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGK

--------ETNWPGVSKLPWYNM------------HRPS-------------IYYKRRVKDVFKQFD---------------------------------
        | .||...||||||.            | ..              ....  |..|. ..                                 
RHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKC

--RHALDLVERMLTLDPLQASRIIAKDALDAEYF
    |.||...||..|| .  || |..||. .||
CDPQAIDLLKKMLQYDPDK--RITAEQALQHPYF
Kinase CRK7-p1_b.AA CRK7 119-343 42 1.2e-114 387.15 In-house 75-343 (343) Show / Hide 
Range on Protein: 119-343
Range on HMM: 75-343/343
Sequence Identity: 42% (116 aa)

SPPDGNIYKGSIYMVFEYMDHDLTGLSDRPGMR-FTVPQIKCYMKQLLTGLYYCHINQVLHRDIKGSNLLIDNKGNLKLADFGLARSFSNDQ-NAQLTNR
.. . . .|||.||||||||||| || . . |  |   |.||.||||| |. ||| . .||||||.||.|..|.|..|.||||||| .  .   ...|||
DASEFKKHKGSFYMVFEYMDHDLMGLLESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNR

VITLWYRPPELLLGCTKY--------------------------------------GPAVDMWSVGCIFAELLYGKPVLTGKNEQDQLAKIFEFCGTPDE
|||||||||||||| ..|                                      ||..||||.|||..||. .|| . |.|| .|| ||.. ||.|  
VITLWYRPPELLLGEERYTEQHILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNP

TNWPGVSKLPWYNMHRPSIYYKRRVKDVFK------QFDRHALDLVERMLTLDPLQASRIIAKDALDAEYF
 ||| | ||||.|. .|   |.||.   |        ... .|||   ||.|||    |. |...|. ..|
NNWPEVMKLPWWNTMKPKRQYNRRLREEFYHHKKPVFMPKECLDLLDKMLCLDPKK--RFTAEECLQHDWF
Kinase CRK7-p1_b.AA CDK7 127-343 42 2.7e-96 256.94 In-house 74-288 (288) Show / Hide 
Range on Protein: 127-343
Range on HMM: 74-288/288
Sequence Identity: 42% (92 aa)

KGSIYMVFEYMDHDLTGLSDRPGMRFTVPQIKCYMKQLLTGLYYCHINQVLHRDIKGSNLLIDNKGNLKLADFGLARSFSNDQNAQLTNRVITLWYRPPE
| .|..||..|| ||          .|   || ||...| ||.||| | .||||.|  |||..  | ||.|||||||..    |  .|  |.| ||| ||
KSNIQLVFDFMDWDLEVVIKDKSIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSP-NRIYTHQVVTRWYRAPE

LLLGCTKYGPAVDMWSVGCIFAELLYGKPVLTGKNEQDQLAKIFEFCGTPDETNWPGVSKLPWYNMHRPSIYY-KRRVKDVFKQFDRHALDLVERMLTLD
|| |   ||..|||||||||||||.   | | | .. ||| .||.  ||| | .||...... |.  ..   | .   ...|      .|||...|.|..
LLFGARHYGTGVDMWSVGCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMN

PLQASRIIAKDALDAEYF
|..  |. . ..|  .||
PCK--RWTCTQCLKMPYF
Kinase CRK7-p1_b.AA Pkinase 26-343 30 2.2e-93 321.37 Pfam 1-293 (293) Show / Hide 
Range on Protein: 26-343
Range on HMM: 1-293/293
Sequence Identity: 30% (102 aa)

FEKLEQIGEGTYGQVYMAREKDTNEIVALKKVRMDNEKEGFPITAIR--EIKILKKLQHENVIKLKEIVTSTGPEQDDPKETQKDAPKGAKEKSPSPPDG
......||.|..|.|| ...|.|..|||.|... ..||.....|..|  ||.|.|.|.|.|...|......                             
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----------------------------

NIYKGSIYMVFEYMDH-----DLT----GLSDRPGMRF--TVPQIKCYMKQLLTGLYYCHINQVLHRDIKGSNLLIDNKGNL----KLADFGLARSFSND
   |..||||.||...     ||     .   . . .|  .  ..|.||.|.| ||.||| . ..|||.| .|.||||.|..    |..|||||. |.. 
---KDHIYMVMEYCEGGLYVMDLFDYIST---WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-

QNAQLTNRVITLWYRPPELLLGCTKYGPAVDMWSVGCIFAELLYGKPVLTGK----NEQDQLAKIFEFCGTPDETNWPGVSKLPWYNMHRPSIYYKRRVK
 |  .| .. |.||..||...|...|||.|||||.|||..|.| |.|   |.    |  ||...|..  |.| . .||  .  ....  |.  . ..  .
NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH--W-HF-HW

DVFKQFDRHALDLVERMLTLDPLQASRIIAKDALDAEYF
 . .  .. ..|.....|..||  ..|. |...|  ..|
TF-HNWSEECKDFIKWCLCKDP--KKRPTAEQILQHPWF
Kinase CRK7-p1_b.AA PITSLRE 129-343 45 1.6e-89 303.71 In-house 77-295 (295) Show / Hide 
Range on Protein: 129-343
Range on HMM: 77-295/295
Sequence Identity: 45% (101 aa)

SIYMVFEYMDHDLTGLSDRPG---MRFTVPQIKCYMKQLLTGLYYCHINQVLHRDIKGSNLLIDNKGNLKLADFGLARSFSNDQNAQLTNRVITLWYRPP
.||||.||..||| .| .       .|. ..||| | ||| |  . | | ..||| | ||||. .||.||..|||||| .       .|  |.||||| |
KIYMVMEYVEHDLKSLMENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSP-IKPYTPCVVTLWYRAP

ELLLGCTKYGPAVDMWSVGCIFAELLYGKPVLTGKNEQDQLAKIFEFCGTPDETNWPGVSKLPWYNMHR-PSIYYKRRVKDVFK---QFDRHALDLVERM
|||||| || ..||||||||||||.. .|| ..||.| ||. .||   ||| |  |||...||  .|    . |     .  |.        ..||  .|
ELLLGCKKYSTPVDMWSVGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQM

LTLDPLQASRIIAKDALDAEYF
||..|  . || | |||. ..|
LTYNP--KNRITASDALKHPWF
Kinase CRK7-p1_b.AA S_TKc 26-343 26 1.1e-86 295.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 26-343
Range on HMM: 1-231/231
Sequence Identity: 26% (89 aa)

FEKLEQIGEGTYGQVYMAREKDTNEIVALKKVRMDNEKEGFPITAIREIKILKKLQHENVIKLKEIVTSTGPEQDDPKETQKDAPKGAKEKSPSPPDGNI
.|.|..||.|..|.|| .|.|.|..|||.|...         ....|||.|||| .|.|..||...  .                               
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-------------------------------

YKGSIYMVFEYMDH---DLTGLSDRPGMR-----FTVPQIKCYMKQLLTGLYYCHINQVLHRDIKGSNLLIDNKGNLKLADFGLARSFSNDQNAQLTNRV
  ...|||.||.|.   ||  . .. | .     |.  ....||.|.. .| ||| ....|||.| .|.|.|.  ..|..|||||| .        |  .
--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFC

ITLWYRPPELLLGCTKYGP-AVDMWSVGCIFAELLYGKPVLTGKNEQDQLAKIFEFCGTPDETNWPGVSKLPWYNMHRPSIYYKRRVKDVFKQFDRHALD
 |.||..||.|    .||. ..|.||.|||..|.|.|.|         |....|. .|                                    .. |.|
GTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG------------------------------------SPEAKD

LVERMLTLDPLQASRIIAKDALD-------AEYF
.....|. ||  . |. | .||         ..|
FIRKCLQKDP--EKRPTA-EALQDEWDIKCHPWF
Kinase CRK7-p1_b.AA CDK5 132-343 43 6.5e-80 252.09 In-house 75-287 (287) Show / Hide 
Range on Protein: 132-343
Range on HMM: 75-287/287
Sequence Identity: 43% (94 aa)

MVFEYMDHDLTGLSDRPGMRFTVPQIKCYMKQLLTGLYYCHINQVLHRDIKGSNLLIDNKGNLKLADFGLARSFSNDQNAQLTNRVITLWYRPPELLLGC
.|||..| ||    |  .     . || .| ||| || .|| ..||||| |  ||||  .|.|||||||||| |    .   .  |.|||||||  |.| 
LVFEFCDQDLKKYMDSCNGEMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRC-YSHEVVTLWYRPPDVLMGS

TKYGPAVDMWSVGCIFAELL-YGKPVLTGKNEQDQLAKIFEFCGTPDETNWPGVSKLPWYN---MHRPSIYYKRRVKDVFKQFDRHALDLVERMLTLDPL
 .|   .||||.||||||.   |.|   | ...||| .||.  ||| | .||...||| |.     .|.   .   . . .. | . .|| ..|| ..| 
KHYSTSIDMWSCGCIFAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPN

QASRIIAKDALDAEYF
|  || ||.||   ||
Q--RISAKAALHHPYF
Kinase CRK7-p1_b.AA CDK9 124-343 38 6.6e-75 255.17 In-house 86-340 (340) Show / Hide 
Range on Protein: 124-343
Range on HMM: 86-340/340
Sequence Identity: 38% (100 aa)

NIYKG--SIYMVFEYMDHDLTGLSDRPGMRFTVPQIKCYMKQLLTGLYYCHINQVLHRDIKGSNLLIDNKGNLKLADFGLARSFS---NDQNAQ--LTNR
| ||.  ..|.||.. .||| ||   .  .|.   ||  |..|. |||| | | .|||| |  | ||   | |||||||||| ||   ||.      |||
NRYKDRATFYLVFDFCEHDLAGLLSNMNVKFSLGHIKKMMQHLMNGLYYIHRNKILHRDMKAANVLITKDGILKLADFGLARAFSQPKNDAPNRPLYTNR

VITLWYRPPELLLGCTKYGPAVDMWSVGCIFAELLYGKPVLTGKNEQDQLAKIFEFCGTPDETNWPGVSKLPWYNMH------RPSIYYKRRVKDVFKQF
|.||||||||||||   |||..|||  ||| ||.    |.. |  || ||. | . ||   .  ||.. ... .|              ||.|||  | .
VVTLWYRPPELLLGDRNYGPPIDMWGAGCIMAEMWTRSPIMQGNTEQHQLQLISQLCGSITPDVWPNCENMELWNKMSSEPNSELPKGQKRKVKDRMKNY

DR------------------------HALDLVERMLTLDPLQASRIIAKDALDAEYF
 .                        .|..|....|..|| .  |. . .|||  .|
MKFDAPDSKTDPFGKNVKQHDSATDQQACHLIDKLLNIDPKK--RMDSDEALDHDWF
Kinase CRK7-p1_b.AA PFTAIRE 132-343 42 6e-67 228.72 In-house 74-287 (287) Show / Hide 
Range on Protein: 132-343
Range on HMM: 74-287/287
Sequence Identity: 42% (93 aa)

MVFEYMDHDLTGLSDRPGMRFTVPQIKCYMKQLLTGLYYCHINQVLHRDIKGSNLLIDNKGNLKLADFGLARSFSNDQNAQLTNRVITLWYRPPELLLGC
.||||.. ||    |.         .. .. ||| || |||  .|||||.|  |||| ..| ||||||||||  |        . |.|||||||  ||| 
FVFEYVHTDLCQYMDKHPGGMHPNNVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHT-YSHEVVTLWYRPPDVLLGS

TKYGPAVDMWSVGCIFAELLYGKPVLTGK-NEQDQLAKIFEFCGTPDETNWPGVSKLPWYNMHRPS--IYYKRRVKDVFKQFD--RHALDLVERMLTLDP
| |   .||| ||||| |.. |.|.  |  . .||| |||.  ||| |  ||||..|| |. |.    .|  .  . .. . .   || ||.  || . |
TEYSTHLDMWGVGCIFVEMMWGQPAFPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEP

LQASRIIAKDALDAEYF
 .  |. |..|.  .||
RD--RVSAQEAMQHPYF
Kinase CRK7-p1_b.AA CDK10 129-343 40 1.1e-60 207.94 In-house 74-285 (285) Show / Hide 
Range on Protein: 129-343
Range on HMM: 74-285/285
Sequence Identity: 40% (88 aa)

SIYMVFEYMDHDLTGLSDRPGMRFTVPQIKCYMKQLLTGLYYCHINQVLHRDIKGSNLLIDNKGNLKLADFGLARSFSNDQNAQLTNRVITLWYRPPELL
||..| .| . ||  | |     ||  |.|| | |.| || | | | ..|||.| ||||.  || .|.||||||| ...     .| ...||||| ||||
SIFLVMQYCEQDLASLLDNMPQPFTETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKP-MTPKMVTLWYRAPELL

LGCTKYGPAVDMWSVGCIFAELLYGKPVLTGKNEQDQLAKIFEFCGTPDETNWPGVSKLPWYNMHRPSIYYKRRVKDVFKQFDRHALDLVERMLTLDPLQ
|||..   |.||| |||| .||| .||.. |  |  |.  | .  |||.|. ||| |.||  . .  .      .|  |.   .  . |.. ..  .| .
LGCRTQTTAIDMWAVGCILGELLVHKPLMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKK

ASRIIAKDALDAEYF
  |  | ..|...||
--RATAEECLESSYF
Kinase CRK7-p1_b.AA CRK7 26-94 70 3.3e-47 160.74 In-house 1-72 (343) Show / Hide 
Range on Protein: 26-94
Range on HMM: 1-72/343
Sequence Identity: 70% (51 aa)

FEKLEQIGEGTYGQVYMAREKDTNEIVALKKVRMDNE---KEGFPITAIREIKILKKLQHENVIKLKEIVTS
.|...||||||||||| |. |.|.|.|||||||||||   |||||||||||||||. |.|.|...||||||.
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTD
Kinase CRK7-p1_b.AA CDK5 26-94 60 2.3e-36 112.04 In-house 1-69 (287) Show / Hide 
Range on Protein: 26-94
Range on HMM: 1-69/287
Sequence Identity: 60% (42 aa)

FEKLEQIGEGTYGQVYMAREKDTNEIVALKKVRMDNEKEGFPITAIREIKILKKLQHENVIKLKEIVTS
.||.| ||||||| || ||.|.| ||||||.||.|.| || | |||||| .|| |.|.|.. |  .. |
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHS
Kinase CRK7-p1_b.AA PITSLRE 26-92 58 9.3e-36 125.11 In-house 1-70 (295) Show / Hide 
Range on Protein: 26-92
Range on HMM: 1-70/295
Sequence Identity: 58% (41 aa)

FEKLEQIGEGTYGQVYMAREKDTNEIVALKKVRMD--NEKEGFPITAIREIK-ILKKLQHENVIKLKEIV
|..| .|.||||| || |..| |.||||||.. |.   ||||||||..|||. ||. |||.|....||||
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIV
Kinase CRK7-p1_b.AA CDK10 26-92 59 3.4e-34 116.16 In-house 1-67 (285) Show / Hide 
Range on Protein: 26-92
Range on HMM: 1-67/285
Sequence Identity: 59% (40 aa)

FEKLEQIGEGTYGQVYMAREKDTNEIVALKKVRMDNEKEGFPITAIREIKILKKLQHENVIKLKEIV
||||  .|||||| || ||.  ..||||||||||| ||.| || ..|||..|....|||...|.|.|
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVV
Kinase CRK7-p1_b.AA CDK7 26-88 47 3e-32 82.84 In-house 1-67 (288) Show / Hide 
Range on Protein: 26-88
Range on HMM: 1-67/288
Sequence Identity: 47% (32 aa)

FEKLEQIGEGTYGQVYMAREKDTNEIVALKKVR----MDNEKEGFPITAIREIKILKKLQHENVIKL
.||...||||... || |... |..||| ||..     .  | |   |||||||||. .||.||| |
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGL
Kinase CRK7-p1_b.AA CDK9 26-91 53 8.5e-32 106.82 In-house 1-77 (340) Show / Hide 
Range on Protein: 26-91
Range on HMM: 1-77/340
Sequence Identity: 53% (41 aa)

FEKLEQIGEGTYG-----------QVYMAREKDTNEIVALKKVRMDNEKEGFPITAIREIKILKKLQHENVIKLKEI
.|||  || ||.|            |. ||.| .  .||.||| |.|||||||||| ||||.|. |.||||. | ||
YEKLAKIGQGTFGQVLQGRKSRNSEVFKARHKKNKRMVAMKKVLMENEKEGFPITALREIKMLQLLKHENVVNLIEI
Kinase CRK7-p1_b.AA PFTAIRE 26-92 46 1.9e-22 75.84 In-house 1-66 (287) Show / Hide 
Range on Protein: 26-92
Range on HMM: 1-66/287
Sequence Identity: 46% (31 aa)

FEKLEQIGEGTYGQVYMAREKDTNEIVALKKVRMDNEKEGFPITAIREIKILKKLQHENVIKLKEIV
.||||  |||.|  || .. . .. .|||| .|...| || | |||||   || |.| |.. |  |.
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQQE-EGTPFTAIREASLLKNLKHANIVCLHDII
Kinase CRK7-p1_b.AA Pkinase_Tyr 26-203 25 9.8e-19 64.08 Pfam 1-159 (270) Show / Hide 
Range on Protein: 26-203
Range on HMM: 1-159/270
Sequence Identity: 25% (49 aa)

FEKLEQIGEGTYGQVYMAREK----DTNEIVALKKVRMDNEKEGFPITA------IREIKILKKL-QHENVIKLKEIVTSTGPEQDDPKETQKDAPKGAK
 ......||| .|.||... |    .|.  || |...     ||    .      .||.||.|.| .|.|...|  ..|                     
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT---------------------

EKSPSPPDGNIYKGS--IYMVFEYMDH-DL-TGLSDR--PGMRFTVPQIKCYMKQLLTGLYYCHINQVLHRDIKGSNLLIDNKGNLKLADFGLAR
            ...  ||.|.||| | || . | ..  .. ..|.... ..  |   |. | . ..  |||.   | |.....  | .||||||
----------DQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase CRK7-p1_b.AA TyrKc 26-317 19 4.6e-11 -43.82 SMART 1-280 (280) Show / Hide 
Range on Protein: 26-317
Range on HMM: 1-280/280
Sequence Identity: 19% (62 aa)

FEKLEQIGEGTYGQVYMAREKDTNEIVALKKVRMDNEKEGFPITAIREIKILKKL--QHENVIKLKEIVTSTGPEQDDPKETQKDAPKGAKEKSPSPPDG
 ......||| .|.|| .. |   . || |... |          .||..|..||  .|.|...|  ..|. |                           
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-------------------------

NIYKGSIYMVFEYMDH-DLTGLSDRPGMRFTVPQIKCYMKQLLTGLYYCHINQVLHRDIKGSNLLIDNKGNLKLADFGLARSFSND--------QNAQ--
 .| . ...|.|||.| ||     ... ......   .. |   |  | | ... |||.   | |.....  | .||||.|   .|           .  
FMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKE

--LTNRVITLWYRPPELLLGCTKYGPAVDMWSVGCI------FAELLYGKPVL--TGKNEQDQLAKIFEFCGTPDETNWPGVSKLPWYNMHRPSIYYKRR
   .. .. .   .|| .  . |. .. | || |        . .  |  ...      |  .. |  .    |..   | .|    .  . |.  |.  
HKGGKTMLPIRWMAPECINYG-KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS----F-VCCPDEMYQ-I

VKDVFKQ-------FDRHALDL
 |.  .        |     ..
MKQCWHEDPEDRPTFSEIHECF