Gene CDC2-S2_g (S.moellendorffii)

CDC2-S2_g

Species: S.moellendorffii
Alias: CDC2-S2_g
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2-smoe2

Sequence

Name Sequence Type Origin Length Description Download
CDC2-S2_g.AA Protein None 331 None Fasta, JSON
CDC2-S2_g.NA RNA None 996 None Fasta, JSON
CDC2-S2_g.kin_dom Protein Kinase Domain None 274 None Fasta, JSON

Protein domain

Protein domains of CDC2-S2_g.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CDC2-S2_g.AA S_TKc 11-292 27 4.8e-62 213.35 SMART 5-231 (231) Show / Hide 
Range on Protein: 11-292
Range on HMM: 5-231/231
Sequence Identity: 27% (81 aa)

RLLGAGPDGEVRVGFHRKTGDKVAMKKIYEHECLYDAIINESEILEEVAHDNVVNFLGLTCNNQGTFMVMELMDG---SLSDVISSRK-------LGEHD
|..| |  |.|. . |.||| .||.|.|       . |..| .||..  |.|.|....   . .  .||||..||   .| |.| .|.       . | .
RKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

IRAVMRQILEGLAWIHAHGIVHQDVKTSNVLVKRDGEKNKFVVKLADFATARRLRTRPWSNKVGTLTFNAPELLKGATSFGT-AIDVWGAGCIFAEMLLG
.| .|.||...|. .| |||.| |.| .|.|. .       ..|..||  ||.|     .  .||. . |||.|    ..|. ..|.|  |||..||| |
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCG

SDPFDVPDDGDSLNYFVADFAKKLDIDGCGMGYQDRRRERARERILEKMVWWKAEDVRSGMKDPDAVELLKRMLAIDPARRISVQNALK-------MPYF
  ||.           ..   ||.                                      .|.| ......|  ||..|...  ||.       .|.|
YPPFP----------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CDC2-S2_g.AA Pkinase 11-292 24 7.8e-57 199.93 Pfam 5-293 (293) Show / Hide 
Range on Protein: 11-292
Range on HMM: 5-293/293
Sequence Identity: 24% (76 aa)

RLLGAGPDGEVRVGFHRKTGDKVAMKKIYEHECLYDAIIN-----ESEILEEVAHDNVVNFLGLTCNNQGTFMVMELMDG-----SLSDVIS---SRKL-
| .|.|  |.|. . |..||..||.|.|  ..   .  ..     | .|. .. |.|.| ...   ...   ||||...|     .|.|.||   .... 
RKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY

-GEHDIRAVMRQILEGLAWIHAHGIVHQDVKTSNVLVKRDGEKNKFVVKLADFATAR---RLRTRPWSNKVGTLTFNAPELLKGATSFGTAIDVWGAGCI
  |.... .|.|||.||. .|..||.| |.| .|.|....|. .   ||..||  |.     . .  .  .||. . |||...|..  |...|.|..|||
FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCI

FAEMLLGSDPFDVPD------DGDSLNYFVADFAKKLDID--GCGMGYQDRRRERARERILEKMVWWKAEDVRSGMKDPDAVELLKRMLAIDPARRISVQ
..|||.|  ||.  .      | . . . . .   . |..   ... .  .|. . .          . . ..    .... ...|..|. ||..|.. .
LYEMLCGRPPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAE

NALKMPYF
 .|. |.|
QILQHPWF
Kinase CDC2-S2_g.AA CMGC 26-203 20 8e-43 137.96 In-house 34-342 (513) Show / Hide 
Range on Protein: 26-203
Range on HMM: 34-342/513
Sequence Identity: 20% (63 aa)

HRKTGDKVAMKKIYEHECLYDA-------------IINESEILEEVA-----------------HDNVVNFLGLTCNNQ-----------------GTFM
|..|. .||.||| . .   .              .. | .||...                  | |.|. .     ..                   ..
HHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYL

VMELMDGSLSDVISSRK----------LGEHD------------IRAVM------RQILEGLA--WIHAHG--IVHQDVKTSNVLVKRDGEK--------
|.|.|| .| ..| . .          | |              |.  |      .|||.||.   .| |.  |.| | | .|.|.  ..|         
VFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKS

-------NKFVVKLADFATARRLRTR-----------------------PWSNKVGTLTFNAPELLKGA---------TSFGTAIDVWGAGCIFAEMLLG
        ....|..||  || . ..                       | .. | |.   |||.| |.         . ..|.||.|..|||||||..|
EDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTG

-------SDPF
        .|.
YQSLIFRGKPL
Kinase CDC2-S2_g.AA CAMK 12-192 16 4.6e-40 126.31 In-house 1-323 (425) Show / Hide 
Range on Protein: 12-192
Range on HMM: 1-323/425
Sequence Identity: 16% (55 aa)

LLGAGPDGEVRVGFHRKTG------------DKVAMKKIY-----------------------------EHECLYDAIINESEILEEVA-------HDNV
 || |  |.|. ..|..|.             |||.| |                              . ..  . . .| ||.  .        | |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNFLGLTC------------NNQG--------TFMVM---ELMDG-----SLSDVISSR----------------KLGEHDIRAVMRQILEGLAWIHAHG
....                . .          .|||   |...|      | | | ..                .. |.. | ..|||..... .| |.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHQDVKTSNVLVKRDGEKNK------------FVVKLADFATARRLRT-------------------------RPWSNKVGTLTFNA-PELLKG-----
||| | |  |.|.  ... .             . .|..||  |....                           . .  .||. . | ||.|.|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------ATSFGTAIDVWGAGCI
         .  | ..|.| .|.|
MQNATDEEKPYYGPKCDMWSCGVI
Kinase CDC2-S2_g.AA STE 7-203 22 7.2e-37 127.75 In-house 1-268 (359) Show / Hide 
Range on Protein: 7-203
Range on HMM: 1-268/359
Sequence Identity: 22% (64 aa)

ASGARLLGAGPDGEVRVGFHRK---------------TGDKVAMKKIYEHEC------------------LYDAIINESEILEEVA--HDNVVNFLGLTC
  | . .| |  |.|  . ..|               ||. .|.|..   .|                    . |..| .|. .    |.|.|...|   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NN-------QGTFMVMELMD-GSLSDVIS---SRKLG------------EHDIRAVMRQILEG-LAWIHAHGIVHQDVKTSNVLVKRDGEKNKFVVKLAD
..       .  ...||.|| |||.|.|    ... .            |. |... ||||.| |. .| |.|.| |.| .|.|.          |||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----------VKLCD

FATARRLRT-----------------RPWS-NKVGTLTFNAPELLKG-----ATSFGTAIDVWGAGCIFAEMLLGSDPF
| .. .|                      .   |||  . ||| ...         .|  |.|  ||   ||. |  |.
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPW
Kinase CDC2-S2_g.AA CDK 24-199 30 1.8e-36 114.08 In-house 18-221 (284) Show / Hide 
Range on Protein: 24-199
Range on HMM: 18-221/284
Sequence Identity: 30% (65 aa)

GFHRKTG-----DKVAMKKI-YEHECLYDA--IIN-----ESEILEEVAHDNVVN----FLGL-TCNN------QGTFMVMELMDGSLSDVISSRKLGEH
. ...||     . ||.|||  |.| . ..   ..     |  .| |  |.|.|.    ...  ...|         .||.| ||  |. ...       
ARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD-------

DIRAVMRQILEGLAWIHAHGIVHQDVKTSNVLVKRDGE-KNKFVVKLADFATARRL--------RTRPWSNKVGTLTFNAPELLKGATSFG--TAIDVWG
 |.  |.|.|.||. .| ..|.| | |..| |. ..|| |   ..|.|||  ||           .|. ...| ||   ||||| |..  .  |.||.|.
-IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVK-CGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWS

AGCIFAEMLL---G
.|||||||..   .
VGCIFAEMFTDVTR
Kinase CDC2-S2_g.AA CDK7 8-198 34 2.3e-35 91.31 In-house 2-198 (288) Show / Hide 
Range on Protein: 8-198
Range on HMM: 2-198/288
Sequence Identity: 34% (69 aa)

SGARLLGAGPDGEVRVGFHRKTGDKVAMKKIY---EHECLYDAI----INESEILEEVAHDNVVNFLGLTCNNQGTFMVMELMDGSLSDVISSRK--LGE
   ...|.|  . |  .   .|| .|| |||      .   | |    | |  || |  ||||.. .          .|...||  |  ||   .  |  
EKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILTP

HDIRAVMRQILEGLAWIHAHGIVHQDVKTSNVLVKRDGEKNKFVVKLADFATARRLRT--RPWSNKVGTLTFNAPELLKGATSFGTAIDVWGAGCIFAEM
 .| | | ..| || . |.. | | | |  | |.  .|     ..|.|||  ||      | .. .| |  . ||||| || ..||..|.|  |||||| 
AHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENG-----QLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAEL

LL
.|
ML
Kinase CDC2-S2_g.AA Ciliate-E2 48-292 17 9.4e-33 109.74 In-house 80-365 (365) Show / Hide 
Range on Protein: 48-292
Range on HMM: 80-365/365
Sequence Identity: 17% (61 aa)

IINESEILEEVAHDNVVNFLGLTC--NNQGTFMVMELMDG-SLSDVISSR------------KLGEHDIRAVMRQILE---------------GLAWIHA
| || .|||.. |.|....       ...  ..|||. .| .| | | ..            .. |  |. .|.|||.               .|  .| 
I-NEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHS

HG-IVHQDVKTSNVLVKRDGEKNKFVVKLADFATARRLRTRPWSNK---------------------------------VGTLTFNAPELLKGATS----
 . |.| | | .|.|.          .|..|| ..... .    .                                  .||. . ||| |.|       
KNNIIHRDIKPENILF----------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQ

----FGTAIDVWGAGCIFAEMLLGSDPFDVPDDGDSLNYFVADFAKKLDIDGCGMGYQDRRRERARERILEKMVWWKAEDVRSGMKD-------------
     ....|.| .|.|. ||| |  ||                                            .   |  ...   ..             
KQKGYDYKCDIWSLGVILYEMLFGKPPF--------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWK

------PDAVELLKR----MLAIDPARRIS-VQNALKMPYF
      ...  |.|.    ||  ||  ||.  . .|. |.|
SWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CDC2-S2_g.AA TKL 13-207 18 1.9e-32 114.12 In-house 1-293 (364) Show / Hide 
Range on Protein: 13-207
Range on HMM: 1-293/364
Sequence Identity: 18% (56 aa)

LGAGPDGEVRVGFHRK--------TGDKVAMKKIYEHECLYDAIINES---------------------EILEEVA-------HDNVVNFLGLTCNNQG-
.| |  |||  | .|         ||  ||.||. .|..  . ....                      . .||..       |.|.| |.|  |.... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------TFMVMELM-DGSLSDVISSRKLGEHDIRAVMRQILEGLAWIHAHG--------IVHQDVKTSNVLVKRDGE---------KNKFVVKL
             ..|||..  ||| ...       | .   ...|  |... |...        |.| | |..|.||.....         ..  ..|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

ADFATARRLRTRP---------------------WSNKVGTLTFNAPELLKGAT---------------SFGTAIDVWGAGCIFAEMLLGSDPFDVPD
.|| ..|.. ..                       ....||. . |||.|.|..               .. ...||.  | .. |.| .  |.. ..
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP
Kinase CDC2-S2_g.AA CRK7 76-197 28 1.4e-25 85.0 In-house 86-247 (343) Show / Hide 
Range on Protein: 76-197
Range on HMM: 86-247/343
Sequence Identity: 28% (47 aa)

TFMVMELMDGSLSDVISSR--K-LGEHDIRAVMRQILEGLAWIHAHGIVHQDVKTSNVLVKRDGEKNKFVVKLADFATARRLRT----RPWSNKVGTLTF
..|| | ||  |.    |   .   .  ..  |.|.|||.. .|  .. | |.| ||.|.   ||     ||.|||  || .      ||  |.| ||  
FYMVFEYMDHDLMGLLESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGE-----VKIADFGLARLYNSEEKRRPYTNRVITLWY

NAPELLKGATSF--------------------------------------GTAIDVWGAGCIFAEML
 .|||| |..                                        |..||.|. |||..| .
RPPELLLGEERYTEQHILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELF
Kinase CDC2-S2_g.AA CDC2 19-196 31 3.4e-25 73.94 In-house 13-199 (301) Show / Hide 
Range on Protein: 19-196
Range on HMM: 13-199/301
Sequence Identity: 31% (60 aa)

GEVRVGFHRKTGDKVAMKKI-YEHECLY----DAIINESEILEEVA-HDNVVNFLGLTCNNQGTFMVMELMDGSLSDVIS----S-RKLGEHDIRAVMRQ
|.|  . ...|.. ||.|||  |.|         .| |  .| |   |.|.|       . .  .|| | .|  |         .  .. .. ..  | |
GVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQ

ILEGLAWIHAHGIVHQDVKTSNVLVKRDGEKNKFVVKLADFATARRLRT--RPWS--NKVGTLTFNAPELLKGATSFGTAIDVWGAGCIFAEM
||.|..  |...|.| | | .| |. ..|.     .|.|||  ||   .  |.      | ||   |||.| |.    |..|.|  |||||||
ILQGVHFCHQRRIMHRDLKPQNILIDKKGN-----IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM
Kinase CDC2-S2_g.AA MAPK 78-199 31 4.5e-21 69.43 In-house 93-231 (328) Show / Hide 
Range on Protein: 78-199
Range on HMM: 93-231/328
Sequence Identity: 31% (46 aa)

MVMELMDGSLSDVISSRK-LGEHDIRAVMRQILEG--LAWIHAHGIVHQDVKTSNVLVKRDGEKNKFVVKLADFATARRLRTRP----------------
.|||||.  |  .| |.. | .. |.  | ||| |  |  ||  ...| | | ||.||  ...     .|..||  || . .                  
IVMELMETDLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCD-----LKICDFGLARSIDPEYHHHHQQDDPHCFQKMH

WSNKVGTLTFNAPELLKG--ATSFGTAIDVWGAGCIFAEMLL-G
 .  | |    |||.. .  ..   .|.|.| .||||||||  .
MTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDR
Kinase CDC2-S2_g.AA CDC2 262-292 51 2e-14 40.25 In-house 271-301 (301) Show / Hide 
Range on Protein: 262-292
Range on HMM: 271-301/301
Sequence Identity: 51% (16 aa)

DPDAVELLKRMLAIDPARRISVQNALKMPYF
||....||..||..||..|||.. ||. |||
DPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase CDC2-S2_g.AA CDK7 264-292 37 2.8e-14 34.01 In-house 260-288 (288) Show / Hide 
Range on Protein: 264-292
Range on HMM: 260-288/288
Sequence Identity: 37% (11 aa)

DAVELLKRMLAIDPARRISVQNALKMPYF
|...|...|.. .| .|..   .||||||
DLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase CDC2-S2_g.AA CMGC 260-292 51 1.6e-13 39.89 In-house 481-513 (513) Show / Hide 
Range on Protein: 260-292
Range on HMM: 481-513/513
Sequence Identity: 51% (17 aa)

MKDPDAVELLKRMLAIDPARRISVQNALKMPYF
. ||.|..|||.|| .||..||... ||..|||
CCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CDC2-S2_g.AA MAPK 260-292 48 3.7e-12 38.12 In-house 296-328 (328) Show / Hide 
Range on Protein: 260-292
Range on HMM: 296-328/328
Sequence Identity: 48% (16 aa)

MKDPDAVELLKRMLAIDPARRISVQNALKMPYF
...|.|. ||..||..|| .||.|. ||  |||
NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase CDC2-S2_g.AA CDK 245-292 31 1e-11 33.56 In-house 252-284 (284) Show / Hide 
Range on Protein: 245-292
Range on HMM: 252-284/284
Sequence Identity: 31% (15 aa)

LEKMVWWKAEDVRSGMKDPDAVELLKRMLAIDPARRISVQNALKMPYF
..|. ..               .|| .||. ||..||| . ||..|||
VTKLPDY---------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CDC2-S2_g.AA TyrKc 7-269 19 1.5e-11 -36.05 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-269
Range on HMM: 1-280/280
Sequence Identity: 19% (61 aa)

ASGARLLGAGPDGEVRVGFHRKTGDKVAMKKIYEHECLYDAIINESEILEEV--AHDNVVNFLGLTCNN-------QGTFMVMELMD-GSLSDVISSRK-
 .  . || |  |||. |  .    .|| |.. |.     ....| .|. ..   |.|.|...|            .  ..|||.|. |.| | . ... 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LGEHDIRAVMRQILEGLAWIHAHGIVHQDVKTSNVLVKRDGEKNKFVVKLADFATARRLRTR------PWSNKV-----GT--LTFN--APELLKGATS
 |   |    . || .| . .| ....| |  . |.||....     .|| .||  .| .             ..     |   |     ||| .   ..
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYG

-FGTAIDVWGAGCIFAEML-LGSDPFDVP----DDGDSLNYFVADFAKKLDIDGCGMGYQDRRRER--------ARERILEKMVW-WKA-EDVRSGMKDP
 | |. |||  |    |.. .|  |   .     . . .  .| .            ||  .. .         . . . . | . |..  . |  ... 
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQ------------GYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

DAVELL
  .|..
--HECF
Kinase CDC2-S2_g.AA CRK7 262-292 29 9.5e-09 26.09 In-house 313-343 (343) Show / Hide 
Range on Protein: 262-292
Range on HMM: 313-343/343
Sequence Identity: 29% (9 aa)

DPDAVELLKRMLAIDPARRISVQNALKMPYF
..... ||  ||. ||  |.... .|  ..|
PKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase CDC2-S2_g.AA Pkinase_Tyr 19-148 23 1.3e-08 29.74 Pfam 13-155 (270) Show / Hide 
Range on Protein: 19-148
Range on HMM: 13-155/270
Sequence Identity: 23% (35 aa)

GEVRVGFHR----KTGDKVAMKKI--YEHECL--YDAIINESEILEEV-AHDNVVNFLGLTC-NNQG--TFMVMELMDG-SLSDVISSR-----KLGEHD
|||. |  .    .|. .|| |..  . ..     .. ..| .|. .   |.|.|...|      .    ..|||.| . .| |   ..     .|  .|
GEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKD

IRAVMRQILEGLAWIHAHGIVHQDVKTSNVLVKRDGEKNKFVVKLADF
.    .|| .|... ......| |. . |.||..     ..||| .||
LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-----NNVVKICDF
Kinase CDC2-S2_g.AA CAMK 262-292 25 5.4e-07 17.81 In-house 395-425 (425) Show / Hide 
Range on Protein: 262-292
Range on HMM: 395-425/425
Sequence Identity: 25% (8 aa)

DPDAVELLKRMLAIDPARRISVQNALKMPYF
....  |...||  || .|.... .|. | .
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CDC2-S2_g.AA STE 263-292 25 0.004656 6.79 In-house 328-359 (359) Show / Hide 
Range on Protein: 263-292
Range on HMM: 328-359/359
Sequence Identity: 25% (8 aa)

PDAVELLKRMLAIDPARRISVQNALK--MPYF
|.  . ... | .||  | ...  ||   | .
PEFKDFINKCLQKDPNKRPTASQLLKSEHPFI