Gene CDC2-1 (S.moellendorffii)

CDC2-1

Species: S.moellendorffii
Alias: CDC2-1
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2

Sequence

Name Sequence Type Origin Length Description Download
CDC2-1.AA Protein None 335 None Fasta, JSON
CDC2-1.NA RNA None 1008 None Fasta, JSON
CDC2-1.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of CDC2-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CDC2-1.AA CDC2 1-284 62 1.1e-215 670.12 In-house 1-301 (301) Show / Hide 
Range on Protein: 1-284
Range on HMM: 1-301/301
Sequence Identity: 62% (190 aa)

YEKVEKIGEGTYGVVYKARDRITNETIALKKIRLDQEDEG--VPSTAIREISLLKEMQ-HGNIVRLQDVVHCEKKLYLVFEYLDLDLKKHMD--NSPDFA
|.|.|||||||||||||..|. ||. .|||||||.|||||  ||||||||||.|||.. | |||.|.||.|. .|||.|||||| |||| ||  ....  
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

KSPRMIKTFLYQMIRGLAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFT--HEVVTLWYRAPEILLGSRHYSTPVDMWSVGCIFAE
 .|  .| ..||...|...||..|..||||||||.|||.  | .|.||||||||||||.|| |  ||||||||||||||||...|||||||||.||||||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAE

M---INQRPLFPGDSEIDELFKIFRILGTPNEETWPGVTSLPDFKSAFPKWLPKDLATLVPG---------LEHAGVDLLSKMLCLDPSSRITARAALEH
|   .. .|||.||||||.|||||||||||||.||||||.|||.|. ||.| |.|| ...|          |.. |.|||..||..||. ||.|..||.|
MFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQH

DYF
 ||
PYF
Kinase CDC2-1.AA CDK5 1-284 61 7.2e-195 621.74 In-house 1-287 (287) Show / Hide 
Range on Protein: 1-284
Range on HMM: 1-287/287
Sequence Identity: 61% (178 aa)

YEKVEKIGEGTYGVVYKARDRITNETIALKKIRLDQEDEGVPSTAIREISLLKEMQHGNIVRLQDVVHCEKKLYLVFEYLDLDLKKHMDNSPDFAKSPRM
|||.|||||||||.|||||.. | | .|||..|||.|||||||||||||.||||..| ||||| ||.| |||| ||||..| ||||.||.  .   ....
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNG-EMDMHI

IKTFLYQMIRGLAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSRHYSTPVDMWSVGCIFAEMI-NQRP
|| |.||. .|||.||.|.||||||||||||| ..   |||||||||||||||||...|||||||||.| .|.||.||||..||||.|||||||. . ||
IKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNG-ELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRP

LFPGDSEIDELFKIFRILGTPNEETWPGVTSLPDFK---SAFPKWLPKD-LATLVPGLEHAGVDLLSKMLCLDPSSRITARAALEHDYF
|||| .. |.|..||.|.|||.|..||..| |||.|    ..|.. ..  .. .||.|.  | |||.||| ..|  ||.| |||.| ||
LFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase CDC2-1.AA CDK 1-284 55 4.6e-192 619.96 In-house 1-284 (284) Show / Hide 
Range on Protein: 1-284
Range on HMM: 1-284/284
Sequence Identity: 55% (179 aa)

YEKVEKIGEGTYGVVYKARDRITN-----ETIALKKIRLDQ-----EDEGVPSTAIREISLLKEMQHGNIVRLQDVVHCE-----------KKLYLVFEY
|||.||||||||||||||||..|.     . .||||||...     |.||.|.|||||||||||. | |||.| ||.| .           .|||.||||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

LDLDLKKHMDNSPDFAKSPRMIKTFLYQMIRGLAYCHSHRVLHRDLKPQNLLIDRRTN----ALKLADFGLARAFGI------PVRTFTHEVVTLWYRAP
.| |||| ||           ||....|..|||.||||....||||||||.||... .     ||.|||||||||||      |.||.||||||||||||
MDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

EILLGSRHYS--TPVDMWSVGCIFAEMIN---QRPLFPGDSEIDELFKIFRILGTPNEETWPGVTSLPDFKSAFPKWLPKDLATLVPGLEHAGVDLLSKM
|.||||.|||  ||.||||||||||||..    .|||||||||| |||||||.|||.|..|||||.|||.                        |||.||
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------DLLNKM

LCLDPSSRITARAALEHDYF
||.||. ||.| .||.|.||
LCYDPKKRISAEQALQHPYF
Kinase CDC2-1.AA CMGC 1-284 30 2.7e-156 517.76 In-house 1-513 (513) Show / Hide 
Range on Protein: 1-284
Range on HMM: 1-513/513
Sequence Identity: 30% (159 aa)

YEKVEKIGEGTYGVVYKARDRITN--------------ETIALKKIRLDQ---------EDEGVPSTAIREISLLKEMQ----------------HGN-I
||...||||||||||||.||. ||              | .|.|||....         | .|.|..|.|||..||...                | | |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VRLQDVVHCEK-----------------KLYLVFEYLDLDLKKHMDNSP---------DFAKSP----------RMIKTFL------YQMIRGLA--YCH
|.|.|... ..                 .|||||||.| ||.. ..| .          .              ..|| |.      ||..|||.  |||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

SHR--VLHRDLKPQNLLIDRRTNA-------------------LKLADFGLARAFGIP---------------------VRTFTHEVVTLWYRAPEILLG
||.  ..||||||.|.||. ..                     ||..||||||.....                     .|..||.|||.||||||||||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

SRHYS---------TPVDMWSVGCIFAEMINQ--------RPLFPGDSE-----------IDELFKIFRILGTPN---------------EETWPGVTSL
..||.         ||.||||||||||||..         .|||||.||           || |||||..||||.               ||.||....|
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PDF----------------KSA----------FPKWLPKDLATLVPG-----------------------------------LEHAGVDLLSKMLCLDPS
|..                ..           ||.| ||..  |.|.                                   . . ..|||.|||..||.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

SRITARAALEHDYF
 ||||  ||.|.||
KRITAEQALQHPYF
Kinase CDC2-1.AA CDK7 1-284 44 8.99999999999e-147 394.13 In-house 1-288 (288) Show / Hide 
Range on Protein: 1-284
Range on HMM: 1-288/288
Sequence Identity: 44% (129 aa)

YEKVEKIGEGTYGVVYKARDRITNETIALKKIR----LDQEDEGVPSTAIREISLLKEMQHGNIVRLQDVVHCEKKLYLVFEYLDLDLKKHM-DNSPDFA
|||...||||....||||.|  |.. .| |||.     .. . |.  |||||| .|.|||| |.. | |.      ..|||...| ||     |.|  . 
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

KSPRMIKTFLYQMIRGLAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSRHYSTPVDMWSVGCIFAEMI
  |  || .  .. .|| ||| . .||||||| |||..     ||.|||||||..| | | .|| ||| |||||| | | ||| | |||||||||||| .
--PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENG-QLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELM

NQRPLFPGDSEIDELFKIFRILGTPNEETWPGVTSLPDFKSAFPKWLP---KDLATLVPGLEHAGVDLLSKMLCLDPSSRITARAALEHDYF
   | .||||.|| | .||..||||.||.||......|.   | .. .     |  .        .||...|. ..|. |.|.. .|...||
LRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDY-IKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase CDC2-1.AA PCTAIRE 1-284 52 5.3e-139 468.09 In-house 1-291 (291) Show / Hide 
Range on Protein: 1-284
Range on HMM: 1-291/291
Sequence Identity: 52% (153 aa)

YEKVEKIGEGTYGVVYKARDRITNETIALKKIRLDQEDEGVPSTAIREISLLKEMQHGNIVRLQDVVHCEKKLYLVFEYLDLDLKKHMDNSPDFAKSPRM
| |..| |||||  ||| | . |.  .||| |||. | || | |||||.||||...| ||| | |..| .. | |||||.| |||. ||.      .   
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMNM-HN

IKTFLYQMIRGLAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSRHYSTPVDMWSVGCIFAEMINQRPL
.| ||.|. |||||||  ..||||||||||||. |   |||||||||||  .| .|. ||||||||| |..|.||  |||..||| |||||.||   |||
VKLFLFQLLRGLAYCHRRKILHRDLKPQNLLINERG-ELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPL

FPGDS------EIDELFKIFRILGTPNEETWPGVTSLPDFKS-AFPKWLPKDLATLVPGLE---HAGVDLLSKMLCLDPSSRITARAALEHDYF
|||          |.|  |||||||| |.|||||.|...|..  ||..... | .  | |.     . |||...| . . .|. | .|..| ||
FPGSTDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase CDC2-1.AA PFTAIRE 1-284 52 6.8e-138 464.41 In-house 1-287 (287) Show / Hide 
Range on Protein: 1-284
Range on HMM: 1-287/287
Sequence Identity: 52% (152 aa)

YEKVEKIGEGTYGVVYKARDRITNETIALKKIRLDQEDEGVPSTAIREISLLKEMQHGNIVRLQDVVHCEKKLYLVFEYLDLDLKKHMDNSPDFAKSPRM
|||.|| |||.|  |||.. .|..  .||| ||| |..||.| ||||| ||||...| ||| | |..| .. | .||||.. ||.. ||  |  .  |. 
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRL-QQEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPG-GMHPNN

IKTFLYQMIRGLAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSRHYSTPVDMWSVGCIFAEMINQRPL
.. ||.|..|||.|||  ||||||||||||||   .  |||||||||||  .| .|. ||||||||| | .||||  ||| .||| ||||| ||.  .|.
VRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLI-SHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPA

FPGD-SEIDELFKIFRILGTPNEETWPGVTSLPDFK-SAFP--KWLPKDLATLVPGLE--HAGVDLLSKMLCLDPSSRITARAALEHDYF
|||     | | |||..||||.|.|||||..|| .|  .|.     || |   .| ..    . ||..||| . |  |. | .|..|.||
FPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase CDC2-1.AA PITSLRE 1-284 45 5e-129 434.96 In-house 1-295 (295) Show / Hide 
Range on Protein: 1-284
Range on HMM: 1-295/295
Sequence Identity: 45% (137 aa)

YEKVEKIGEGTYGVVYKARDRITNETIALKKIRLD--QEDEGVPSTAIREIS-LLKEMQHGNIVRLQDVV--HCEKKLYLVFEYLDLDLKKHMDNSP---
.... .|.||||||||.|.|. |.| .|||.. ..  .| || | |..|||. .|...|| ||| .  .|      | |.|.||.. |||  |.|     
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

-DFAKSPRMIKTFLYQMIRGLAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSRHYSTPVDMWSVGCIF
  |  .   ||... |  || .. |.. ..|||||  |||.    . ||..|||||| .| |.. .|  ||||||||||.|||.. ||||||||||||||
QPFKPG--EIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGI-LKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIF

AEMINQRPLFPGDSEIDELFKIFRILGTPNEETWPGVTSLPDFKS-A-FPKWLPKDLATLVP---GLEHAGVDLLSKMLCLDPSSRITARAALEHDYF
||.| ..|||.|.||||.. .||  .|||.|  |||.|.|| .|    ||.  .  |  ..|    .   | ||| .||...|  |||| .|| |..|
AEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase CDC2-1.AA CDK4 1-284 47 5.6e-117 394.92 In-house 1-290 (290) Show / Hide 
Range on Protein: 1-284
Range on HMM: 1-290/290
Sequence Identity: 47% (140 aa)

YEKVEKIGEGTYGVVYKARDRITNETIALKKIRLDQEDE--GVPSTAIREISLLK---EMQHGNIVRLQDVVHC------EKKLYLVFEYLDLDLKKHMD
|..|  |||| || ||.||| .|   .|||..|   ..|  |.|   |||||...    . | |||.| || |       | |. .|||  | ||.  .|
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

NSPDFAKSPRMIKTFLYQMIRGLAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSRHYSTPVDMWSVGC
. |    .|  ||    |..||. . ||||. ||||||||.|.  .   .||||||||| ..     .|  ||||||||||.|| |  | ||||||||||
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILV-TSDGHVKLADFGLARIYSFQMA-LTPVVVTLWYRAPEVLLQS-YYNTPVDMWSVGC

IFAEMINQRPLFPGDSEIDELFKIFRILGTPNEETWPGVTSLPDFKSAFPKWLPKDLATLVPGLEHAGVDLLSKMLCLDPSSRITARAALEHDYF
||||| . ||||.| || | | ||| . |.| |. ||   |||   ..||   |. .  ..| ..  | ||| |||| ... |..|...|.|.||
IFAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLP--WDHFPQRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase CDC2-1.AA Pkinase 1-284 35 4.5e-115 393.38 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1-284
Range on HMM: 1-293/293
Sequence Identity: 35% (108 aa)

YEKVEKIGEGTYGVVYKARDRITNETIALKKIRLDQEDEGVPSTAIR--EISLLKEMQHGNIVRLQDVVHCEKKLYLVFEYLDLDLKKHMDNS------P
|....|||.|..|.|||.... |... |.|.|... |..... |..|  ||...|...| ||||| |... ....|.|.||.. .|. .|| .       
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWR

DFAK--SPRMIKTFLYQMIRGLAYCHSHRVLHRDLKPQNLLIDRRTNA---LKLADFGLARAF-GIPVRTFTHEVVTLWYRAPEILLGSRHYSTPVDMWS
. .   |.. .| ..||..|||.||||....||||||.|.|||.. .    .|..|||||. |   . . .|. ..|.||.|||...|...|...|||||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

VGCIFAEMINQRPLFPGD----SEIDELFKIFRILGTPNEETWPGVTSLPDFKSAFPKWLPKDLATLVPGLEHAGVDLLSKMLCLDPSSRITARAALEHD
.|||..||.. ||.|||.    . .|....|.||.|.|... ||   | ..|.  .. | .. . |. . .. .. |.....||.||..|.||. .|.|.
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

YF
.|
WF
Kinase CDC2-1.AA CRK7 1-284 36 3.3e-107 362.49 In-house 1-343 (343) Show / Hide 
Range on Protein: 1-284
Range on HMM: 1-343/343
Sequence Identity: 36% (128 aa)

YEKVEKIGEGTYGVVYKARDRITNETIALKKIRLDQE---DEGVPSTAIREISLLKEMQHGNIVRLQDVVHC--------EKK--LYLVFEYLDLDLKKH
||... ||||||| ||||..  |.| .||||.|.| |    || | |||||| .|....| |||.| ..|          ..|   |.|||| | ||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

MDNS--PDFAKSPRMIKTFLYQMIRGLAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPV--RTFTHEVVTLWYRAPEILLGSRHY-----
...    .|...   .| |. |.  |..|||   .||||.|  |.|.. . . .|.||||||| .      | .|  |.|||||.|| |||  .|     
LESKEMHHFSHQ--QCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGE-VKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHI

---------------------------------STPVDMWSVGCIFAEMINQRPLFPGDSEIDELFKIFRILGTPNEETWPGVTSLPDFKSAFPKW----
                                  . .||||.|||..|  ...|.|.|  |.. | ||..| |.|| . || |. || ..   ||     
LKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNR

-LPKDLATLVP--GLEHAGVDLLSKMLCLDPSSRITARAALEHDYF
 | ..         .  . .||| |||||||. |.||  .|.||.|
RLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase CDC2-1.AA S_TKc 1-284 31 3.9e-105 356.51 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-284
Range on HMM: 1-231/231
Sequence Identity: 31% (94 aa)

YEKVEKIGEGTYGVVYKARDRITNETIALKKIRLDQEDEGVPSTAIREISLLKEMQHGNIVRLQDVVHCEKKLYLVFEYLDL---DLKKHMDNSPD----
||...|||.|..|.|||.|.. |..  |.|.|.          ...|||..||. .| |||.| || .  ..||.|.||.|    ||...... .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

FAKSPRMIKTFLYQMIRGLAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSRHYST-PVDMWSVGCIFA
|  .. ... ..||....|.|||||...||||||.|.|.|.    .|..|||||| .       |. ..|.||.|||.|    .|.. ..|.||.|||..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILY

EMINQRPLFPGDSEIDELFKIFRILGTPNEETWPGVTSLPDFKSAFPKWLPKDLATLVPGLEHAGVDLLSKMLCLDPSSRITARAALE-------HDYF
||.  .|.||      .....|...|                                    . . |...|.|. ||. |.||  ||.       | .|
EMLCGYPPFP------QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CDC2-1.AA Pkinase_Tyr 1-149 28 3.9e-14 48.48 Pfam 1-160 (270) Show / Hide 
Range on Protein: 1-149
Range on HMM: 1-160/270
Sequence Identity: 28% (47 aa)

YEKVEKIGEGTYGVVYKARDR----ITNETIALKKIRLDQEDEGVPSTA------IREISLLKEM-QHGNIVRLQDVVH-CEKK--LYLVFEYLDL-DLK
 .. .|.||| .|.|||.. .     |. . | |...     ||  . .      .||....|.. .| |||||  |.   ..   .|.|.||  . ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

KHMDNS--PDFAKSPRMIKTFLYQMIRGLAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARA
..  .   .. . .. ..  . .|  .|..| .|..  ||||   | |... .|  | .||||||.
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-NNVVKICDFGLARD
Kinase CDC2-1.AA TyrKc 1-284 20 2e-12 -21.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-284
Range on HMM: 1-280/280
Sequence Identity: 20% (67 aa)

YEKVEKIGEGTYGVVYKARDRITNETIALKKIRLDQEDEGVPSTAIREISLLKEM--QHGNIVRLQDVVHCE-------KKLYLVFEYLDL-DLKKHM-D
 .. .|.||| .|.|||.. .   .. | |... |          .||......   .| |||||  |.  .       . |..|.|| .. |||..  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NSPDFAKSPRMIKTFLYQMIRGLAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIP-------VRTFT----HEV--VTLWYRAPEILLGSR
. |.   ...    | .|  .| .| ||... ||||   | |....    | .||||.|. .             .    ..   . .   ||| .   .
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG

HYSTPVDMWSVGCIFAEMINQ-RPLFPG-------DSEIDELFKIFRILGTPNE----ETWPGVTSLPDFKSAFPKWLPKDLATLVPGLEHAGVDLLSKM
 ..|  | || |    |.     .  ||       ..|. |. |  . .  | .                                ..   .  .. .. 
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------FVCCPDEMYQIMKQC

LCLDPSSRITARAALEHDYF
   ||..| | ..   |..|
WHEDPEDRPTFSEI--HECF