Gene Chk1L_b-1 (S.moellendorffii)

Chk1L_b-1

Species: S.moellendorffii
Alias: Chk1L_b-1
External Links:
Annotation:

Classification

Group: CAMK
Family: Chk1L

Sequence

Name Sequence Type Origin Length Description Download
Chk1L_b-1.AA Protein None 360 None Fasta, JSON
Chk1L_b-1.NA RNA None 1083 None Fasta, JSON
Chk1L_b-1.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of Chk1L_b-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Chk1L_b-1.AA CAMKL 30-286 33 3.2e-106 340.01 In-house 1-297 (297) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-297/297
Sequence Identity: 33% (102 aa)

FELVRDIGSGNFAVARLVRD-RVTQELFAVKYIERG----DKIDEK------------VQREIINHRSMR---HPNIVRFKEVMLTPTH------LAIVM
..... .| |.|.. .| .. | |.|  |.| |..     | . .|            ..|||  .....   ||||... ||. ||.|      . .||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAAGGE--LFERICNA----TRFSEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLD--G-SPAPRLKICDFGYSKSSV-F----DSQPKSTVGTP
||. |||  ||..|..      |..|.|||..|.|..|.|.|||.. ..|||.|.|| |||  | .    .||.||| |          .   |   |.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

AYIAPEVLST--KNYDGKIADVWSCGVTLYVMLVGAYPFEDPEDP----KNFRKTIGRILNVQYSIPQSVDISPEAHDLLSRIFVGNPNQRINIAGIKNH
.| |||...   | |||. .|.|||||.||.|..|..||.|. ..    .|. .   .|    | .|  ...| ...||.... . ||..|..|  |.||
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

PWF
||.
PWM
Kinase Chk1L_b-1.AA CAMK 35-286 23 3.5e-105 339.96 In-house 1-425 (425) Show / Hide 
Range on Protein: 35-286
Range on HMM: 1-425/425
Sequence Identity: 23% (101 aa)

DIGSGNFAVARLVRDRVTQ------------ELFAVKYIER-----------------------------GDKIDEKVQREIINHRS-------MRHPNI
 .|.|.|.. .|.... |.            . .|.| |..                              .|  ..|.|||  ...       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRFKEVML------------TPTH--------LAIVM---EYAAGGEL----FERICNA---------------TRFSEDEARFFFQQLISGVSYCHNME
... ||.             | ..        . .||   ||. ||||    |..|.                  ||.|.|||..|.|..|.| |||.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VCHRDLKLENTLLDGSPAPR---------------LKICDFGYSKSSVF------------------------DSQPKSTVGTPAYIA-PEVLST-----
..|||||.|| ||| .   .               .||.||| ..                            .   |  .|||.|.| ||||.      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KNYDGKIADVWSCGVTLYVMLVGAYPFEDP---EDPK------NFRKTIGRILNVQYS-IPQSVD-------------ISPE--------AH
        | |.|. .|.||||| ||.||.| .||...   |...      | ...  .|.. .|. .|  ..             || |        . 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLLSRIFVGNPNQRINIAGIKNHPWF
||.... . .|..|..|. ..||||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Chk1L_b-1.AA S_TKc 30-286 33 1.3e-96 328.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-231/231
Sequence Identity: 33% (92 aa)

FELVRDIGSGNFAVARLVRDRVTQELFAVKYIERGDKIDEKVQREIINHRSMRHPNIVRFKEVMLTPTHLAIVMEYAAG--GELFERICNATR------F
.|..| ||.| |.. ...|.. |....|.| |       |...|||  ... .|||||....|. . .|| .||||. |  |.||..|..  |      |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

SEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDGSPAPRLKICDFGYSKSSVFDSQPKSTVGTPAYIAPEVLSTKNYDGKIADVWSCGVTLYVMLV
.| .|||...|..... |||.. ..||||| || |||     ..|||||| ..        .. .||| |.|||||    |... .|.||||..|| ||.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GAYPFEDPEDPKNFRKTIGRILNVQYSIPQSVDISPEAHDLLSRIFVGNPNQRINIAGIKN-------HPWF
|  ||.      .  ... .|.            |||| |....... .|..|. .  . .       ||||
GYPPFP------QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Chk1L_b-1.AA AMPK 30-286 42 4.4e-94 279.71 In-house 1-254 (254) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-254/254
Sequence Identity: 42% (111 aa)

FELVRDIGSGNFAVARLVRDRVTQELFAVKYIER----GDKIDEKVQREIINHRSMRHPNIVRFKEVM-LTPTHLAIVMEYAAGGELFERICNATRFSED
. .   || | |    .     |.|  |.| ...    ... .|..|||| . ...|||.|..  ||   ||| . .||||..|||||. |.  .| .|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDGSPAPRLKICDFGYSKSSVFDSQPKSTVGTPAYIAPEVLSTKNYDGKIADVWSCGVTLYVMLVGAY
||. |||| ||||.|||.  . |||||.|| |||     ..|| ||| |.      . |   | | | |||. | | | |   |.||||| ||.|| |  
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLD--HNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL

PFEDPEDPKNFRKTIGRILNVQYSIPQSVDISPEAHDLLSRIFVGNPNQRINIAGIKNHPWF
||.|.. |. ..|    |.| .|.||.  ..||||.||....   .|..||.|  |.|||||
PFDDENTPTLYKK----IKNGEYYIPK--FLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase Chk1L_b-1.AA MARK 30-286 36 1.2e-93 306.51 In-house 1-262 (262) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-262/262
Sequence Identity: 36% (96 aa)

FELVRDIGSGNFAVARLVRDRVTQELFAVKYIERGDKID----EKVQREIINHRSMRHPNIVRFKEVML--TPTH-LAIVMEYAAGGELFERICNA--TR
..... || |..|. .|.... |.. .|.| .|. .. |    ..|.|||  .... ||||... .|.   |..| . ..|||| ||||...| ..   |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FSEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDGSPAPRLKICDFGYSKSSVFDSQPKSTVGTPAYIAPEVLSTKNYDGKIADVWSCGVTLYVML
 .|.||| .|.|..|.|.|||.. ..|||.|.|| |.|       ||.|||.|     ..  ..  |||.| |||... | |||. .|.||.|| ||.|.
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGAYPFEDPEDPKNFRKTIGRILNVQYSIPQSVDISPEAHDLLSRIFVGNPNQRINIAGIKNHPWF
.| .||.  .| ... .   .||. .|.||    .|.|...|..|... ||..|. |  | .|||.
CGYFPFD--GDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase Chk1L_b-1.AA Pkinase 30-286 32 4.7e-87 300.31 Pfam 1-293 (293) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-293/293
Sequence Identity: 32% (95 aa)

FELVRDIGSGNFAVARLVRDRVTQELFAVKYIERGDKIDEKVQR-----EIINHRSMRHPNIVRFKEVMLTPTHLAIVMEYAAGG----ELFERIC--NA
....| ||||.|.. .. ... |....||| |.. .. ..| |.     ||  .....||||||..... ...|. .||||. ||    .||..|   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TRF--SEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLD--GSPAPRLKICDFGYSKS--SVFDSQPKSTVGTPAYIAPEVLSTKNYDGKIADVWSC
..|  ||.|..|.. |...|. |||.| ..|||||.|| |.|  | .....|||||| .|      .| ... .||| |.||||. . .|.|. .|.|||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVTLYVMLVGAYPFEDP------EDPKNFRKTIGRILNVQYSIPQSVD---------------ISPEAHDLLSRIFVGNPNQRINIAGIKNHPWF
|..|| || |  || .       .. . .... |..|  ... . |.                .|.|. |......  .|..|.... |..||||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Chk1L_b-1.AA AGC 30-286 23 2.4e-85 219.86 In-house 1-395 (395) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-395/395
Sequence Identity: 23% (95 aa)

FELVRDIGSGNFAVARLVRDR------VTQELFAVKYIERGD---KID----EKVQ--------------REIINHRSMR--------HPNIVR-FKEVM
||... || | |   .|||..       |....|.| ..  .   ...    |...              |.|  . . .        ||.||.  .   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

LTPTH--LAIVMEYAA---------GG-ELFERIC---NATRFSEDEARFFFQQ-------LISGVSYCHN-MEVCHRD-LKLENTLLDGSPAPRLKICD
 ...|  | .||||.          || ||| ...   .  ||.|..|||.. .       ..... | |. | . ||| ||.|| |||      .|..|
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED--GHIKLTD

FGYSKSSVFDS---------------------------------------------------QPKSTVG--TPAYIAPEVLSTKNYDGKIADVWS--CGV
|| .|  . |                                                    . .. .|  || |.|||.|      || .| ||   |.
FGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGC

TLYVMLVGAYPFEDPEDP------KNFRKTIGRILNVQYSIPQS--------------VDISPEAHDLLSRIFVGNPNQRIN----------IAGIKNHP
 .| ||.|  || . ..       .|  ..  .|.| .| |..               . .|||| ||... .. .|..|.           .  |||||
LMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP

WF
||
WF
Kinase Chk1L_b-1.AA Ciliate-E2 30-286 22 9e-74 251.4 In-house 1-365 (365) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-365/365
Sequence Identity: 22% (86 aa)

FELVRDIGSGNFA-----VARLVRDR------------------VTQELFAVKYI-ERGDKIDEKVQREI--INH-----------RSMRHPNIVRFKEV
..... ||.|||.       ..|. .                  |.. ..|.|.. ... .. .......  ||.           ... ||||....|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

ML--TPTHLAIVMEYAAGGELFERICNA-----------TRFSEDEARFFFQQLIS---------------GVSYCHNME-VCHRDLKLENTLLDGSPAP
    . ... .||||. ||.||..| |             .|.| |......|...               .. |.|.   ..|||.|.|| |.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

RLKICDFGYSKSSVFDSQPKS--------------------------------TVGTPAYIAPEVLSTKNYDG--------KIADVWSCGVTLYVMLVGA
 .||.|||.||    |.| ..                                ..||| | |||.|. |.||.        . .|.||.||.|| || | 
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

YPFEDPEDPKNFRKTIGRILNVQYSIP----------------QSVDISPEAHDLLSR----IFVGNPNQRIN-IAGIKNHPWF
.||            .  |.. ....|                   ..|.|. ||...    ... .|..||. .  |.|||||
PPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase Chk1L_b-1.AA Ciliate-E2-Unclassified 30-286 25 2.9e-70 239.75 In-house 1-352 (352) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-352/352
Sequence Identity: 25% (89 aa)

FELVRDIGSGNFAVARLVRDRVTQELF-----AVKYIERGDKIDEKVQREIINH-----------------------RSMRHPNIVRFKEVMLTPTHLAI
..... ||.|.|.. ...... .. ..     . |.... .|. .... ||.|                        ... ||.||.. ..  .  .. |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEYAAGGELFERICN-----------------ATRFSEDEAR-----FFFQQLISGVSYCHNME-VCHRDLKLENTLLDGSP-APRLKICDFGYSKSSV
||||. ||.|.. |..                   .|.| .|.     |.| |...| .|.|    ..|||.|.|| |.| .    ..||.||| || . 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

FDSQ----------------PKSTVGTPAYI----APEVLSTKNYDG---KIADVWSCGVTLYVMLVGAYPFEDPEDPK----------------NFRKT
 ...                 ....||| |.    |||||  .|||.   . .|.||.|| || || | |||.|. . .                 ... 
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

IGRILNVQYSIPQS--VDISPEAHDLLS----RIFVGNPNQRINIAGIKNHPWF
. ...... . .|.   ..|||| |...    .... |||.||..  |.|||||
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase Chk1L_b-1.AA QIK 30-286 35 3e-69 236.37 In-house 1-272 (272) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-272/272
Sequence Identity: 35% (99 aa)

FELVRDIGSGNFAVARLVRDRVTQELFAVKYIERGDKIDE----KVQREIINHRSMRHPNIVRFKEVMLTPTHLAIVMEYAAGGELFERICNATR-----
... | || ||||| .| | |.| .  |.| | .  ..||    |. ||.    ...||.|..  .|| |   . ||.||. .||.|. .|.  |     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDK-SQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------FSEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDGSPAPRLKICDFGYSKSSVFDSQPKSTVGTPAYIAPEVLSTKNYDGK
                .|.|||. |.|..|.| |||. .. ||||| || |||       || |||.|  .  .   .. .|.|.| |||..  |.||| 
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMN--IKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGP

IADVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTIGRILNVQYSIPQSVDISPEAHDLLSRIFVGNPNQRINIAGIKNHPWF
 .|.|| || |||.  || ||  . .. | |.   |.|  .. || .  .| .  .|  .  | .|..|..|. |..|.| 
KVDIWSMGVVLYVLVCGALPFDGKTLQ-NLRQ---RVLSGKFRIPFF--MSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase Chk1L_b-1.AA RSK 32-286 30 1.5e-64 220.73 In-house 1-278 (278) Show / Hide 
Range on Protein: 32-286
Range on HMM: 1-278/278
Sequence Identity: 30% (87 aa)

LVRD--IGSGNFAVARLVRDRVTQELFAVKYIERGDKIDEKVQ------REIINHRSMR-HPNIVRFKEVMLTPTHLAIVMEYAAGGELFERICNATR--
|  .  .| | . . | .... |. ..|.| ...  ||. .        .|.      . ||.||. ...  |...| ..|||  |||||.....  .  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKK-AKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG

-FSEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDG-SPA-PRLKICDFGYSKSSVFD--SQPKSTVGTPAYIAPEVLS---TKN-YDGKIADVWS
 ||||||.| . .... |.. |   . |||||.|| |.|  |    ..|..||| .| .. |  .. .. ..| .|.|||.|     .. .| | .|.||
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHD-KACDWWS

CGVTLYVMLVGAYPFEDPEDPKNFRKTIGRILNVQ--YSIPQSVDISPEAHDLLSRIFVGNPNQRIN-----IAGIKNHPWF
 || .| ||.|. ||  |.| .|  ... ||.. .   ..|    .|.|| ||... .  .|..|..     .. ||.||||
LGVLMYEMLTGCPPFQGPND-NNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase Chk1L_b-1.AA ULK 30-286 26 5.7e-64 218.84 In-house 1-329 (329) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-329/329
Sequence Identity: 26% (88 aa)

FELVRDIGSGNFAVARLVRDRVT----QELFAVKYIERGDKIDEK-----------VQREIINHRSMR--------HPNIVRFKEVMLTPTH--LAIVME
..| . .|.| |..    |.  |    .|..|.| |..  .. ..           ...|| . . .         |||||.....  |..|  . |.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YAAGGELFERIC----------NATRFSEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDGSPA----------PRLKICDFGYSKS-SVF---DS
|  || |.. |           .  |.||.||. ||.|...|  . | . . |||.|..| |..   .          ..|||.||| .|. . .   . 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

QPKSTV------GTPAYIAPEVLS----TKNYDGKIADVWSCGVTLYVMLVGAYP----FEDPE-----DPKNFRKTIGR-ILNVQYSIP---QSVDISP
. ...|      ||| | ||..|.     |.|. . .|.|| |. .| ||.| .|    |.|       . .| .....  | . .  .|    .. |||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

EAHDLLSRIFVGNPNQRINIAGIKNHPWF
| .||..| .. ....||..  . |||||
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase Chk1L_b-1.AA TyrKc 30-286 21 5.8e-13 -13.15 SMART 1-280 (280) Show / Hide 
Range on Protein: 30-286
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

FELVRDIGSGNFAV---ARLVRDRVTQELFAVKYIERGDKIDEKVQREIINHRSM--RHPNIVRFKEVMLTP-------THLAIVMEYAAGGELFERICN
 .| . .|.|.| .   ...       .  ||| .  .    |   ||.   ..   .||||||.  | ...         | |||||...| | ... .
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ATR-FSEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDGSPAPRLKICDFGYSKSSVFD--------SQPKST-VGTP-----AYIAPEVLSTKNY
  . .. ..   |  |  .| .| | . . ||||   | |..     . ||.||| |.    |           |..  |.         |||.. .. .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DGKIADVWSCGVTLYVMLVGAYPFEDPEDP----KNFRKTIGRILNVQYSIPQSVD-------ISPEAHDLLSRIFVGNPNQRINIAGIKNHPWF
  |  |||| ||... ..   |  . ....    .. .  | .. .  .  .   |        ..| ... ..    .|..| . . |  |  |
TTK-SDVWSFGVCMWEIF--TYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF