Gene Chk1L_b-2 (S.moellendorffii)

Chk1L_b-2

Species: S.moellendorffii
Alias: Chk1L_b-2
External Links:
Annotation:

Classification

Group: CAMK
Family: Chk1L

Sequence

Name Sequence Type Origin Length Description Download
Chk1L_b-2.AA Protein None 378 None Fasta, JSON
Chk1L_b-2.NA RNA None 1137 None Fasta, JSON
Chk1L_b-2.kin_dom Protein Kinase Domain None 275 None Fasta, JSON

Protein domain

Protein domains of Chk1L_b-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Chk1L_b-2.AA CAMKL 30-304 32 5.9e-103 329.41 In-house 1-297 (297) Show / Hide 
Range on Protein: 30-304
Range on HMM: 1-297/297
Sequence Identity: 32% (103 aa)

FELVRDIGSGNFAVARLVRD-RVTQELFAVKYIERG----DKIDEK------------VQREIINHRSMR---HPNIVRFKEVMLTPTH------LAIVM
..... .| |.|.. .| .. | |.|  |.| |..     | . .|            ..|||  .....   ||||... ||. ||.|      . .||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAAGGE--LFERICNA----TRFGEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLD--G-SPAPRLKICDFGYSKVSS-IPEEELIQSCLCSFQS
||. |||  ||..|..      |. |.|||..|.|..|.|.|||.. ..|||.|.|| |||  | .    .||.||| |     .               
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFGFSNMYRPC---------------

SVF--DSQPKSTVGTPAYIAPEVLST--KNYDGKIADVWSCGVTLYVMLVGAYPFEDPEDP----KNFRKTIGRILSVQYSIPQSVDISPEAHDLLSRIF
 .|  .   |   |.|.| |||...   | |||. .|.|||||.||.|..|..||.|. ..    .|. .   .| .  | .|  ...| ...||.... 
-IFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKML

VGNPNQRINIAGIKNHPWF
. ||..|..|  |.||||.
QVNPEKRPTIHQIMNHPWM
Kinase Chk1L_b-2.AA CAMK 35-304 23 7.6e-101 325.71 In-house 1-425 (425) Show / Hide 
Range on Protein: 35-304
Range on HMM: 1-425/425
Sequence Identity: 23% (104 aa)

DIGSGNFAVARLVRDRVTQ------------ELFAVKYIER-----------------------------GDKIDEKVQREIINHRS-------MRHPNI
 .|.|.|.. .|.... |.            . .|.| |..                              .|  ..|.|||  ...       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRFKEVML------------TPTH--------LAIVM---EYAAGGEL----FERICNA---------------TRFGEDEARFFFQQLISGVSYCHNME
... ||.             | ..        . .||   ||. ||||    |..|.                  || |.|||..|.|..|.| |||.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VCHRDLKLENTLLDGSPAPR---------------LKICDFGYSKVSSIPE-----------EELIQSCLCSFQSSVFDSQ---------PKSTVGTPAY
..|||||.|| ||| .   .               .||.||| ...    |           | .  .            |          |  .|||.|
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN------------QWTTPTEGQKMKTFCGTPEY

IA-PEVLST-------------KNYDGKIADVWSCGVTLYVMLVGAYPFEDP---EDPK------NFRKTIGRILSVQYS-IPQSVD-------------
.| ||||.              | |.|. .|.||||| ||.||.| .||...   |...      | ...  .|.. .|. .|  ..             
MAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDD

ISPE--------AHDLLSRIFVGNPNQRINIAGIKNHPWF
|| |        . ||.... . .|..|..|. ..||||.
ISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Chk1L_b-2.AA S_TKc 30-304 31 3e-94 320.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 30-304
Range on HMM: 1-231/231
Sequence Identity: 31% (92 aa)

FELVRDIGSGNFAVARLVRDRVTQELFAVKYIERGDKIDEKVQREIINHRSMRHPNIVRFKEVMLTPTHLAIVMEYAAG--GELFERICNATR------F
.|..| ||.| |.. ...|.. |....|.| |       |...|||  ... .|||||....|. . .|| .||||. |  |.||..|..  |      |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

GEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDGSPAPRLKICDFGYSKVSSIPEEELIQSCLCSFQSSVFDSQPKSTVGTPAYIAPEVLSTKNYD
 | .|||...|..... |||.. ..||||| || |||     ..|||||| ...                         .. .||| |.|||||    |.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------------------------TTFCGTPWYMAPEVL---GYG

GKIADVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTIGRILSVQYSIPQSVDISPEAHDLLSRIFVGNPNQRINIAGIKN-------HPWF
.. .|.||||..|| ||.|  ||.      .  ... .|.            |||| |....... .|..|. .  . .       ||||
KCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Chk1L_b-2.AA Pkinase 30-304 30 1.3e-83 288.87 Pfam 1-293 (293) Show / Hide 
Range on Protein: 30-304
Range on HMM: 1-293/293
Sequence Identity: 30% (94 aa)

FELVRDIGSGNFAVARLVRDRVTQELFAVKYIERGDKIDEKVQR-----EIINHRSMRHPNIVRFKEVMLTPTHLAIVMEYAAGG----ELFERIC--NA
....| ||||.|.. .. ... |....||| |.. .. ..| |.     ||  .....||||||..... ...|. .||||. ||    .||..|   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TRF--GEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLD--GSPAPRLKICDFGYSKVSSIPEEELIQSCLCSFQSSVFDSQPKSTVGTPAYIAPEV
..|   |.|..|.. |...|. |||.| ..|||||.|| |.|  | .....|||||| .|. .                   .| ... .||| |.||||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------------Y-NNS-MTTFCGTPWYMAPEV

LSTKNYDGKIADVWSCGVTLYVMLVGAYPFEDP---EDPKNFRKTIGRILSVQYSIPQSVDIS-------------------PEAHDLLSRIFVGNPNQR
. . .|.|. .|.||||..|| || |  || .    ..  . .. | ||.. ... . . ..|                   .|. |......  .|..|
IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKR

INIAGIKNHPWF
.... |..||||
PTAEQILQHPWF
Kinase Chk1L_b-2.AA Ciliate-E2 30-304 22 1.1e-70 241.11 In-house 1-365 (365) Show / Hide 
Range on Protein: 30-304
Range on HMM: 1-365/365
Sequence Identity: 22% (85 aa)

FELVRDIGSGNFA-----VARLVRDR------------------VTQELFAVKYI-ERGDKIDEKVQREI--INH-----------RSMRHPNIVRFKEV
..... ||.|||.       ..|. .                  |.. ..|.|.. ... .. .......  ||.           ... ||||....|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

ML--TPTHLAIVMEYAAGGELFERICNATRFG-----------EDEARFFFQQLIS---------------GVSYCHNME-VCHRDLKLENTLLDGSPAP
    . ... .||||. ||.||..| |   .            | |......|...               .. |.|.   ..|||.|.|| |.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

RLKICDFGYSKVSSIPEEE---LIQSCLCSFQS------------SVFDSQPKSTVGTPAYIAPEVLSTKNYDG--------KIADVWSCGVTLYVMLVG
 .||.|||.||  ......   . |. .. | .             ... . ....||| | |||.|. |.||.        . .|.||.||.|| || |
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

AYPFEDPEDPKNFRKTIGRILSVQYSIP----------------QSVDISPEAHDLLSR----IFVGNPNQRIN-IAGIKNHPWF
 .||            .  |.  ....|                   ..|.|. ||...    ... .|..||. .  |.|||||
KPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase Chk1L_b-2.AA Ciliate-E2-Unclassified 30-304 24 4.7e-65 222.43 In-house 1-352 (352) Show / Hide 
Range on Protein: 30-304
Range on HMM: 1-352/352
Sequence Identity: 24% (89 aa)

FELVRDIGSGNFAVARLVRDRVTQELF-----AVKYIERGDKIDEKVQREIINH-----------------------RSMRHPNIVRFKEVMLTPTHLAI
..... ||.|.|.. ...... .. ..     . |.... .|. .... ||.|                        ... ||.||.. ..  .  .. |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEYAAGGELFERICN-----------------ATRFGEDEAR-----FFFQQLISGVSYCHNME-VCHRDLKLENTLLDGSP-APRLKICDFGYSK---
||||. ||.|.. |..                   .| | .|.     |.| |...| .|.|    ..|||.|.|| |.| .    ..||.||| ||   
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

--VSSIPEEE-----LIQSCLCSFQSSVFDSQPKSTVGTPAYI----APEVLSTKNYDG---KIADVWSCGVTLYVMLVGAYPFEDPEDPK---------
  . .  ..       ......           ....||| |.    |||||  .|||.   . .|.||.|| || || | |||.|. . .         
QNNNCD-TNQQQKMQIWKQQMM-----------WTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI

-------NFRKTIGRILSVQYSIPQS--VDISPEAHDLLS----RIFVGNPNQRINIAGIKNHPWF
        ... . ...... . .|.   ..|||| |...    .... |||.||..  |.|||||
NNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase Chk1L_b-2.AA RSK 32-304 28 3.4e-62 212.94 In-house 1-278 (278) Show / Hide 
Range on Protein: 32-304
Range on HMM: 1-278/278
Sequence Identity: 28% (85 aa)

LVRD--IGSGNFAVARLVRDRVTQELFAVKYIERGDKIDEKVQ------REIINHRSMR-HPNIVRFKEVMLTPTHLAIVMEYAAGGELFERICNATR--
|  .  .| | . . | .... |. ..|.| ...  ||. .        .|.      . ||.||. ...  |...| ..|||  |||||.....  .  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKK-AKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG

-FGEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDG-SPA-PRLKICDFGYSKVSSIPEEELIQSCLCSFQSSVFDSQPKSTVGTPAYIAPEVLS-
 | ||||.| . .... |.. |   . |||||.|| |.|  |    ..|..||| .| ... .... ..                 ..| .|.|||.|  
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMT----------------FCYTIEYMAPEMLKR

--TKN-YDGKIADVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTIGRILSVQ--YSIPQSVDISPEAHDLLSRIFVGNPNQRIN-----IAGIKNHPWF
   .. .| | .|.|| || .| ||.|. ||  |.| .|  ... ||.. .   ..|    .|.|| ||... .  .|..|..     .. ||.||||
ANQQGGHD-KACDWWSLGVLMYEMLTGCPPFQGPND-NNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase Chk1L_b-2.AA ULK 30-304 25 3e-61 209.78 In-house 1-329 (329) Show / Hide 
Range on Protein: 30-304
Range on HMM: 1-329/329
Sequence Identity: 25% (87 aa)

FELVRDIGSGNFAVARLVRDRVT----QELFAVKYIERGDKIDEK-----------VQREIINHRSMR--------HPNIVRFKEVMLTPTH--LAIVME
..| . .|.| |..    |.  |    .|..|.| |..  .. ..           ...|| . . .         |||||.....  |..|  . |.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YAAGGELFERICNATRFGEDE----------ARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDGSPA----------PRLKICDFGYSKVSSIP--EEE
|  || |.. | .  ...||.          |. ||.|...|  . | . . |||.|..| |..   .          ..|||.||| .|. . .  |..
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LIQSCL-CSFQSSVFDSQPKSTV---GTPAYIAPEVLS----TKNYDGKIADVWSCGVTLYVMLVGAYP----FEDPE-----DPKNFRKTIGR-ILSVQ
....|.                    ||| | ||..|.     |.|. . .|.|| |. .| ||.| .|    |.|       . .| .....  | . .
MMMTCVNE--------------KRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQP

YSIP---QSVDISPEAHDLLSRIFVGNPNQRINIAGIKNHPWF
  .|    .. |||| .||..| .. ....||..  . |||||
LQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase Chk1L_b-2.AA ULK 30-304 27 1e-58 201.38 In-house 1-324 (324) Show / Hide 
Range on Protein: 30-304
Range on HMM: 1-324/324
Sequence Identity: 27% (92 aa)

FELVRDIGSGNFAVARLVRDR--VT---QELFAVKYIE----RGDKID-------EKVQREIINHRSMR---HPN--IVRFKEVMLTPTH--LAIVMEYA
..| . .|.| |.     . |   |   ....|.| |.    . .| .       .. ..|| . . .    |||  ||.....  |..|  . |.||| 
YCLNHCLGKGSFG-VKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYC

AGGELFERIC---------NATRFGEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDGSPA----------PRLKICDFGYSKVSSIP--EEELIQ
 || |.. |          .  |. |.||. ||.|...|  . |.. . |||.|..| |.    .          ..|||.||| .|.   .  |. ..|
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

SCLCSFQSSVFDSQPKSTVGTPAYIAPEVLS----TKNYDGKIADVWSCGVTLYVMLVGAYPFEDPEDPKNFR---KTIGR-------ILSVQYSIP---
.|.   .        |  .||| | ||..|.     |.|. . .|.|| |. .| || | |||. .   . .    | |         |   .  .|   
TCVN--E--------KRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP

QSVDISPEAHDLLSRIFVGNPNQRINIAGIKNHPWF
... |||| .||..| .. ....||..  | |||||
KDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase Chk1L_b-2.AA MARK 30-173 36 1.2e-56 183.79 In-house 1-153 (262) Show / Hide 
Range on Protein: 30-173
Range on HMM: 1-153/262
Sequence Identity: 36% (56 aa)

FELVRDIGSGNFAVARLVRDRVTQELFAVKYIERGDKID----EKVQREIINHRSMRHPNIVRFKEVML--TPTH-LAIVMEYAAGGELFERICNA--TR
..... || |..|. .|.... |.. .|.| .|. .. |    ..|.|||  .... ||||... .|.   |..| . ..|||| ||||...| ..   |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FGEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDGSPAPRLKICDFGYS
  |.||| .|.|..|.|.|||.. ..|||.|.|| |.|       ||.|||.|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFS
Kinase Chk1L_b-2.AA AMPK 30-175 41 1.6e-53 157.29 In-house 1-149 (254) Show / Hide 
Range on Protein: 30-175
Range on HMM: 1-149/254
Sequence Identity: 41% (63 aa)

FELVRDIGSGNFAVARLVRDRVTQELFAVKYIER----GDKIDEKVQREIINHRSMRHPNIVRFKEVM-LTPTHLAIVMEYAAGGELFERICNATRFGED
. .   || | |    .     |.|  |.| ...    ... .|..|||| . ...|||.|..  ||   ||| . .||||..|||||. |.  .|  |.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDGSPAPRLKICDFGYSKV
||. |||| ||||.|||.  . |||||.|| |||     ..|| ||| |..
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLD--HNKNIKIVDFGLSNM
Kinase Chk1L_b-2.AA QIK 30-173 36 6.3e-39 135.64 In-house 1-165 (272) Show / Hide 
Range on Protein: 30-173
Range on HMM: 1-165/272
Sequence Identity: 36% (62 aa)

FELVRDIGSGNFAVARLVRDRVTQELFAVKYIERGDKIDE----KVQREIINHRSMRHPNIVRFKEVMLTPTHLAIVMEYAAGGELFERICNATR-----
... | || ||||| .| | |.| .  |.| | .  ..||    |. ||.    ...||.|..  .|| |   . ||.||. .||.|. .|.  |     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDK-SQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------FGEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDGSPAPRLKICDFGYS
                 |.|||. |.|..|.| |||. .. ||||| || |||       || |||.|
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMN--IKIADFGFS
Kinase Chk1L_b-2.AA AMPK 205-304 46 1.9e-38 111.77 In-house 161-254 (254) Show / Hide 
Range on Protein: 205-304
Range on HMM: 161-254/254
Sequence Identity: 46% (46 aa)

GTPAYIAPEVLSTKNYDGKIADVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTIGRILSVQYSIPQSVDISPEAHDLLSRIFVGNPNQRINIAGIKNHPWF
| | | |||. | | | |   |.||||| ||.|| |  ||.|.. |. ..|    |.. .|.||.  ..||||.||....   .|..||.|  |.|||||
GSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKK----IKNGEYYIPK--FLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase Chk1L_b-2.AA MARK 205-304 40 3.1e-35 112.76 In-house 167-262 (262) Show / Hide 
Range on Protein: 205-304
Range on HMM: 167-262/262
Sequence Identity: 40% (40 aa)

GTPAYIAPEVLSTKNYDGKIADVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTIGRILSVQYSIPQSVDISPEAHDLLSRIFVGNPNQRINIAGIKNHPWF
|||.| |||... | |||. .|.||.|| ||.|..| .||.  .| ... .   .||. .|.||    .|.|...|..|... ||..|. |  | .|||.
GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFD--GDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase Chk1L_b-2.AA QIK 201-304 36 3.7e-23 83.27 In-house 175-272 (272) Show / Hide 
Range on Protein: 201-304
Range on HMM: 175-272/272
Sequence Identity: 36% (38 aa)

KSTVGTPAYIAPEVLSTKNYDGKIADVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTIGRILSVQYSIPQSVDISPEAHDLLSRIFVGNPNQRINIAGIKN
.. .|.|.| |||..  |.|||  .|.|| || |||.  || ||  . .. | |.   |.|| .. || .  .| .  .|  .  | .|..|..|. |..
MTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQ-NLRQ---RVLSGKFRIPFF--MSQDCEHLIRHMLVVDPEHRYTIMQICQ

HPWF
|.| 
HRWM
Kinase Chk1L_b-2.AA TyrKc 30-304 20 8.1e-12 -31.59 SMART 1-280 (280) Show / Hide 
Range on Protein: 30-304
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)

FELVRDIGSGNFAV---ARLVRDRVTQELFAVKYIERGDKIDEKVQREIINHRSM--RHPNIVRFKEVMLTP-------THLAIVMEYAAGGELFERICN
 .| . .|.|.| .   ...       .  ||| .  .    |   ||.   ..   .||||||.  | ...         | |||||...| | ... .
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ATR-FGEDEARFFFQQLISGVSYCHNMEVCHRDLKLENTLLDGSPAPRLKICDFGYSKVSSIPEEELIQSC-LCSFQSSVFDS----QPK--STVGTPAY
  . .  ..   |  |  .| .| | . . ||||   | |..     . ||.||| |.         | .   .   ... ..    . |    .     
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSR--------DIYDDDQQGESKDYYRKKEHKGGKTMLPI---RW

IAPEVLSTKNYDGKIADVWSCGVTLYVMLVGAYPFEDPEDP----KNFRKTIGRILSVQYSIPQSVD-------ISPEAHDLLSRIFVGNPNQRINIAGI
 |||.. .. .  |  |||| ||... ..   |  . ....    .. .  | .. .  .  .   |        ..| ... ..    .|..| . . |
MAPECINYGKFTTK-SDVWSFGVCMWEIF--TYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

KNHPWF
  |  |
--HECF