Gene CAMK1c-S3_h (S.moellendorffii)

CAMK1c-S3_h

Species: S.moellendorffii
Alias: CAMK1c-S3_h
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S3_h.AA Protein None 298 None Fasta, JSON
CAMK1c-S3_h.NA RNA None 897 None Fasta, JSON
CAMK1c-S3_h.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S3_h.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S3_h.AA S_TKc 25-281 27 8.9e-64 219.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-281
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

YDVGFELGKGGQGTVHLVSFRMGGKLLAAKSFERSGEREKEIMLKLNGCHGTLEIYDMVEEERKGRWWGSLILELCSC---TLRDRLKMVGR------LA
|... ..|||. |.|...  .  |.. | |   .. .|| .|. |  ..     .||. ..   .. .  ...|.|.    .|.|..|  ||      . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK--HHPNIVKLYDVFQD---DHLY--MVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

DDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDRADEMHHLCGTPGYMSPDVLRAGEGGWPKYYTQ-AVDVWGLGLILY
  .|.|... ... |  .|..|..||| | ||.||..     ..|..|||.|.      ...|||| ||.| ||          |.  ..|.| .| |||
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL----TTFCGTPWYMAPEVL---------GYGKCKCDWWSCGCILY

ELLSGRVAFPEYHSDYVELLLKSVDNVEFALDWSDVTSEAKDLIMGMLEVYPSRRLTVEQVLG-------HPWI
|.|.|.  ||    .. ... | .            ..||||.|...|.. |..|.|. ..|        |||.
EMLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CAMK1c-S3_h.AA CAMK 30-281 19 3.4e-63 202.18 In-house 1-425 (425) Show / Hide 
Range on Protein: 30-281
Range on HMM: 1-425/425
Sequence Identity: 19% (84 aa)

ELGKGGQGTVHLVSFRMGG------------KLLAAKSFERSG-----------------------------------EREKEIMLKLNG------CHGT
.||.|. |.|.|.  .  .            .  |.|  ...                                    .|| ||| ||.|          
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LEIYDMVEEERKGRWW----------------GSLIL---ELCSCT-----LRDRLKMV---------------GRLADDEAAFVTKSLAETLREMHNLG
. .|.. | ....                     ...   |.||       | |...                 ||.  .||... . ... .. .|...
IKLYEVYEDPHYFK-NTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDMKLENVLLTHPA--QP------------YEVKLSDFGVATDRAD--------------------------EMHHLCGTPGYMS-PDVLRA-GEGG
.|||| |.||.||..    ..            . .|..||| |.   .                           |.  ||||.||. | ||.  | . 
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

W-------PKYYTQAVDVWGLGLILYELLSGRVAFPEYHSD----------YVELLLKSVDNVEFALD---------------WSDVTSE--------AK
.        .||....|.| .| ||| .|.|.  | . . .            . |.. . . ..  .               |.|.. |        .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIMGMLEVYPSRRLTVEQVLGHPWI
||| .||.| |..|.|.||.| |||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase CAMK1c-S3_h.AA Pkinase 25-281 27 2.1e-51 181.89 Pfam 1-293 (293) Show / Hide 
Range on Protein: 25-281
Range on HMM: 1-293/293
Sequence Identity: 27% (83 aa)

YDVGFELGKGGQGTVHLVSFRMGGKLLAAKSFERSGEREKE-----------IMLKLNGCHGTLEIYDMVEEERKGRWWGSLILELCSC-----TLRDRL
| .|  .|.|. |.| .   .  ||. | | .....|....           ||..|| ..  ...||..|.  |.. .  ...|.| .      | |..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNI-VRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDYI

K--MVGRL--ADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPAQP-YEVKLSDFGVA----TDRADEMHHLCGTPGYMSPDVLRAGEGGWPKY
.  . |..   ..|. |. . ... |  .|. |..|||.|.||.|. .  ..   ||..|||.|    . .   |...||||.||.| |.|       .|
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----GGQY

YTQAVDVWGLGLILYELLSGRVAFPEY----HSDYVELLLKSVDNVEFALDWSDVT--------------------SEAKDLIMGMLEVYPSRRLTVEQV
|...||.|..|.||||.|.||  ||.     . .    ... .   ..  ||.                       .|.||.| ..|.. |..|.| ||.
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

LGHPWI
| |||.
LQHPWF
Kinase CAMK1c-S3_h.AA AGC 133-281 20 4.2e-46 116.03 In-house 169-395 (395) Show / Hide 
Range on Protein: 133-281
Range on HMM: 169-395/395
Sequence Identity: 20% (50 aa)

MHN-LGVVHRD-MKLENVLLTHPAQPYEVKLSDFGVATD-----------------------------------------------------RADEMHHL
.|. .|..||| .|.||.||..      .||.||| ..                                                        |  . .
LHSHMGIIHRDYLKPENILLDED---GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTF

CG--TPGYMSPDVLRAGEGGWPKYYTQAVDVWG--LGLILYELLSGRVAFPEYHSD-------YVELLLKSVD------NVEFALDW---------SDVT
||  || ||.| .|          |..|.| |.  || ..||.|.|.  |     .         . . ...       | .  ...         . ..
CGPCTPEYMAPEIL----------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFS

SEAKDLIMGMLEVYPSRRLT----------VEQVLGHPWI
.|||||| ..|.. |..||.          .|..  ||| 
PEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase CAMK1c-S3_h.AA Ciliate-E2 95-281 22 5.4e-44 148.89 In-house 111-365 (365) Show / Hide 
Range on Protein: 95-281
Range on HMM: 111-365/365
Sequence Identity: 22% (62 aa)

LILELCSC-TLRDRLK------------MVGRLADDEAAFVTKSLAE---------------TLREMHNLG-VVHRDMKLENVLLTHPAQPYEVKLSDFG
|..|.|.  .|.|..|              ... . |.....| ...                |...|. . ..||| |.||.|.        .|..|||
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--------IKIIDFG

VATDRADE----------------------------------MHHLCGTPGYMSPDVLRAGE-----GGWPKYYTQAVDVWGLGLILYELLSGRVAFPEY
 ...  |.                                   . .|||||||.| .|. ..     ..  |.|. ..|.| || ||||.|.|.  |   
LSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQ--KGYDYKCDIWSLGVILYEMLFGKPPF---

HSDYVELLLKSVDNVEFALD---------------WSDVTSEAKDLIMG----MLEVYPSRRLT-VEQVLGHPWI
      .  .   ...|                  | ... |.||||      ||.. |. |.|  ||.| |||.
------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMK1c-S3_h.AA RSK 106-281 28 7.5e-42 145.36 In-house 90-278 (278) Show / Hide 
Range on Protein: 106-281
Range on HMM: 90-278/278
Sequence Identity: 28% (55 aa)

DRLKMVGR---LADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTH-PAQPYEVKLSDFGVATD-RAD---EMHHLCGTPGYMSPDVLRAGEGGWP
..|.  ..   .  |||.|.   .. ... .| .|..||| |.||.|...   .. ..||.||| .   |.|    ..  |.|  || | .|. ..   .
THLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN--QQ

KYYTQAVDVWGLGLILYELLSGRVAFPEYHSD-YVELLLKSVDNVE--FALD-WSDVTSEAKDLIMGMLEVYPSRRLT-----VEQVLGHPWI
. ...|.|.| || ..||.|.|.. |     |   . ..| . . .  . .. |. .. |||||| .||.. |..||.     .|... |||.
GGHDKACDWWSLGVLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CAMK1c-S3_h.AA CAMK1 133-281 38 1.4e-41 118.64 In-house 124-276 (276) Show / Hide 
Range on Protein: 133-281
Range on HMM: 124-276/276
Sequence Identity: 38% (60 aa)

MHNLGVVHRDMKLENVLLTHPAQPYEVK--LSDFGVATDRA-D--EMHHLCGTPGYMSPDVLRAGEGGWPKYYTQAVDVWGLGLILYELLSGRVAFPEYH
|| .|.|||| | || |.  .    ..|  ..||| ..    |   |   ||||||. |.||   .   .| | .|.|.|. | |.| || |   | .  
MHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK---DKPYDKACDMWSIGVITYILLCGYPPFYDEN

-SDYVELLLKSVDNVEFALD-WSDVTSE-AKDLIMGMLEVYPSRRLTVEQVLGHPWI
  ..   . |. . .||  . | .. .. |||.| .|||| |. |.|.||.| ||||
VDNELFEKIKKCE-YEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CAMK1c-S3_h.AA CAMKL 95-281 28 4.7e-41 128.65 In-house 98-297 (297) Show / Hide 
Range on Protein: 95-281
Range on HMM: 98-297/297
Sequence Identity: 28% (59 aa)

LILELCSCT---LRDRLKMV----GRLADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPA-QPYEVKLSDFGVATD-RA-----DE-MHHLCG
|..|.||     | |...      ||.  .|| .  . . . .  .|..|.|||| |.||.||..   .   .|..||| ..  |      .. ..  ||
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCG

TPGYMSPDVLRAGEGGWPKYYTQAVDVWGLGLILYELLSGRVAFPEYH------SDYVELLLKSVDNVEFALDWSDVTSEAKDLIMGMLEVYPSRRLTVE
.| ||.| ..  .     .|. ..||.| .| ||| .. |.. | . .      ... .|..|     ..   |..|  ...||| .||.| |..| |..
SPPYMAPEIFQGN---NKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIH

QVLGHPWI
|.. ||| 
QIMNHPWM
Kinase CAMK1c-S3_h.AA MSK 107-281 30 2.1e-40 134.31 In-house 91-277 (277) Show / Hide 
Range on Protein: 107-281
Range on HMM: 91-277/277
Sequence Identity: 30% (58 aa)

RLKMVGRLADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDRADE----MHHLCGTPGYMSPDVLRA---GEGGWPKY
...  ..   .|....  .|   .. || .|..|||.|.||.|..      .|||.||| |  .  .    |.  |.|  ||.|..||    ..||    
HIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGG----

YTQAVDVWGLGLILYELLSGRVAFPEYHSDYV------ELLLKSVDNVEFALD---WSDVTSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
| .|.|.|.|| |||..|.|.| |    .|          . | .   || ..   |. .  .||||| ..|.. |..||...  . | |.
YDEACDWWSLGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase CAMK1c-S3_h.AA DCAMKL 106-281 34 7.6e-40 121.27 In-house 104-279 (279) Show / Hide 
Range on Protein: 106-281
Range on HMM: 104-279/279
Sequence Identity: 34% (63 aa)

DRLKMVGRLADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTH-PAQPYEVKLSDFGVATDRAD---EMHHLCGTPGYMSPDVLRAGEGGWPKYYT
| .  ...    .||  .  |.. |. .| ...|||| |.|| |.   .    ..|| ||| |.   .    .   |||| |  | .|.  | |    | 
DAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILM--ETG----YG

QAVDVWGLGLILYELLSGRVAFPEYHSD--YVELLLKSVDNVEFALD---WSDVTSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
  ||.| .| ||| || |   ||   |     | | . .   .| ..   |..... |||||  ||.| | .| | ||.. |||.
CKVDIWAAGVILYILLCG---FPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CAMK1c-S3_h.AA Ciliate-E2a 95-224 33 6e-29 82.37 In-house 76-217 (275) Show / Hide 
Range on Protein: 95-224
Range on HMM: 76-217/275
Sequence Identity: 33% (48 aa)

LILELCSC-TLRDRLKMVGRLADD--EAAFVTKSLA-ETLREMHNLGVVHRDMKLENVLLT--HPA--QPYEVKLSDFGVATDR--ADE--MHHLCGTPG
|..|.|.  .| |..|  .|.     |.. . . |  . |  ||.....||| |.||.|..   .   |. ..|..||| ||.    ..  |.  |||||
LVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPG

YMSPDVLRAGE--GGWPKYYTQAVDVWGLGLILYELLSGRVAFP
|. | ||   |   .  | |.. .|.| .|.|.| ||.|.  |.
YVAPEVLNNKEVLKH--KQYDTKCDMWSCGVIFYILLCGKPPFK
Kinase CAMK1c-S3_h.AA MAPKAPK 118-219 32 1.8e-22 65.96 In-house 104-214 (292) Show / Hide 
Range on Protein: 118-219
Range on HMM: 104-214/292
Sequence Identity: 32% (37 aa)

EAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATD-------RAD----EMHHLCGTPGYMSPDVLRAGEGGWPKYYTQAVDV
||. ..|  .. .. .|...  ||| |.||.| |....   |||.||| |                |.   |.|| || | |. |     . .|    | 
EASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCPVKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFK--EAHTYDKSCDM

WGLGLILYELLSG
| || |.| .|.|
WSLGVIMYIMLCG
Kinase CAMK1c-S3_h.AA MAPKAPK 246-281 55 6.1e-16 45.41 In-house 257-292 (292) Show / Hide 
Range on Protein: 246-281
Range on HMM: 257-292/292
Sequence Identity: 55% (20 aa)

DWSDVTSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
.||..  ||||||  .| . |. |||.|||. ||||
EWSHISEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase CAMK1c-S3_h.AA Ciliate-E2a 246-281 43 1.4e-13 36.38 In-house 239-275 (275) Show / Hide 
Range on Protein: 246-281
Range on HMM: 239-275/275
Sequence Identity: 43% (16 aa)

D-WSDVTSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
. |.....|.|||. .|||..|. |.| .| | ||| 
ECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase CAMK1c-S3_h.AA TyrKc 25-281 17 3.7e-05 -139.22 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-281
Range on HMM: 1-280/280
Sequence Identity: 17% (52 aa)

YDVGFELGKGGQGTVHLVSFRMGGKLLAAKSFERSG----EREKEIMLKL-NGCHGTLEIYDMVEEER------KGRWWGSLILELCSC-TLRDRLKMVG
   | .|| |  |.|..   .      | |.   .      || .|| ||       . .|  . ..       .  .   ...|...   |.|.|.  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM---IVMEYMPHGDLKDYLRKHR

R-LADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDRADE--------MHHLC---GTPG-----YMSPDVLRAGEGG
. |  ..        |.  .  |  ...|||    |.|....     || |||| . |  |.        . .     |. .      |.| ... |.  
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK--

WPKYYTQAVDVWGLGLILYELLSGRVAFPEYHS-----DYVELLLKSVDNVEFALDWSD--------VTSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
    .| . |||  |  ..|...     . |          . ... |.. .      .         ..|  ...    .  |. | | ...  |  .
----FTTKSDVWSFGVCMWEIFTY--GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CAMK1c-S3_h.AA CAMKL 25-41 52 0.001067 7.51 In-house 1-17 (297) Show / Hide 
Range on Protein: 25-41
Range on HMM: 1-17/297
Sequence Identity: 52% (9 aa)

YDVGFELGKGGQGTVHL
|..| .||||. |.| |
YRIGKTLGKGSFGKVKL
Kinase CAMK1c-S3_h.AA Ciliate-E2 25-43 26 0.006192 5.89 In-house 1-19 (365) Show / Hide 
Range on Protein: 25-43
Range on HMM: 1-19/365
Sequence Identity: 26% (5 aa)

YDVGFELGKGGQGTVHLVS
|..   .|.|..|.| ...
YKFIKKIGQGNFGSVYKCK