Gene CAMK1c-S5_y (S.moellendorffii)

CAMK1c-S5_y

Species: S.moellendorffii
Alias: CAMK1c-S5_y
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S5_y.AA Protein None 306 None Fasta, JSON
CAMK1c-S5_y.NA RNA None 921 None Fasta, JSON
CAMK1c-S5_y.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S5_y.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S5_y.AA S_TKc 20-267 27 2.6e-57 197.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-267
Range on HMM: 1-231/231
Sequence Identity: 27% (74 aa)

YTRGERLGCGSQGQVFVLKGAT---SYAGKMFRAGRDAGRELRLMSKLRGCAGVVSLAGFVKERSGGACYGTMVMELCGP---SLFHRLIKGGP------
|. .. .| |. |.|.  .       .| |. .  ... ||.....|  ..  .| | ..  .      .  ||||.|.    .||... | |.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDEEEAAKTIQRLAEALKGIHSSGIVHRDLKPENIFVKLDATAVHEVVIGDFGVATDDPKEMSQCCGTGKYMAPEVTSCKGDARSQSFYTA-AIDVWALG
..| .|.. .. ...||. .|| ||.|||||||||..        .. |.|||.|.      . .|||  ||||||            |.  ..|.|..|
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL----------GYGKCKCDWWSCG

VIAYELLRGYK--QSREIELLRAGELPDGCPLSDEVEDLICGMLAVEPSERLTLDGVLE-------HPWI
.| ||.| ||   .  . ....          |.|. |.|...| ..|..|.|   .|.       |||.
CILYEMLCGYPPFP-QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase CAMK1c-S5_y.AA Pkinase 20-267 25 4.2e-52 184.22 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-267
Range on HMM: 1-293/293
Sequence Identity: 25% (80 aa)

YTRGERLGCGSQGQVFVLKGATS---YAGKMFRAGRDAG---------RELRLMSKLRGCAGVVSLAGFVKERSGGACYGTMVMELCGP-----SLFHRL
|..|...| || |.|.  .   .   .| | ..  ..           .|...| .|. .  .| | ... .  .. .|  ||||.|.      .||...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPN-IVRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDYI

I--KGGPL--DEEEAAKTIQRLAEALKGIHSSGIVHRDLKPENIFVK----LDATAVHEVVIGDFGVA----TDDPKEMSQCCGTGKYMAPEVTSCKGDA
   ..|..  .|.|. . .  ....|. .|| ||.|||||||||...    .||     | |.|||.|    .     |.  |||  ||||||       
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA----CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----

RSQSFYTAAIDVWALGVIAYELLRG---YKQS------REIELLRAGEL-------PDGCPLS-----------------DEVEDLICGMLAVEPSERLT
 ... |. ..|.|..|.| ||.| |   ....      .......           |  |. |                 .|  |.|...|.. |..|.|
-GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

LDGVLEHPWI
 . .|.|||.
AEQILQHPWF
Kinase CAMK1c-S5_y.AA CAMK 25-267 20 3.8e-49 156.09 In-house 1-425 (425) Show / Hide 
Range on Protein: 25-267
Range on HMM: 1-425/425
Sequence Identity: 20% (87 aa)

RLGCGSQGQVFVLKGA-TS--------------YAGKMFR------------------------------AGRDAG---RELRLMSKLRG------CAGV
 || || |.|.  .   |               .| |.                                 ..|     ||...|.||.|         .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLAGFVKERSGGA----------CYGT------MVM---ELCGP-----SLFHRLIKGGP---------------LDEEEAAKTIQRLAEALKGIHSSG
..|  .   .. ..           . |      |||   |.|        || .... |.               ..|.||.. .. ...|.. .|| .
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKPENIFVKLDA-------------TAVHEVVIGDFGVATDDPK--------------------------EMSQCCGTGKYMA-PEVTSCKGDAR
||||||||||| .  .                .. . | ||| |.  ..                           |. .|||  ||| ||| . ||   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

S-------QSFYTAAIDVWALGVIAYELLRGY------KQSREIE-------------LLRAGELP-DGCP-----------------------LSDEVE
.       .  |. ..|.|..||| | .| ||      ......|               ..|.   .  .                       .|.|. 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLICGMLAVEPSERLTLDGVLEHPWI
|||..|| |.|..|.|.. .|.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CAMK1c-S5_y.AA AGC 89-267 20 1.6e-44 111.88 In-house 110-395 (395) Show / Hide 
Range on Protein: 89-267
Range on HMM: 110-395/395
Sequence Identity: 20% (63 aa)

MVMELC-----------GPSLFHRLI---KGGPLDEEEAAKTIQR-------LAEALKGIHS-SGIVHRD-LKPENIFVKLDATAVHEVVIGDFGVATDD
.|||..           |  ||..|    | | .|||.|   .         .. ||  .||  ||.||| ||||||    |      . . ||| ..  
FVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED----GHIKLTDFGLCKEG

PKE-----------------------------------------------------MSQCCG--TGKYMAPEVTSCKGDARSQSFYTAAIDVWA--LGVI
...                                                      .  ||  |  |||||.            |. | | |.  ||..
MNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----------YGKACDWWSFGLGCL

AYELLRG--------------------YKQSREIELLRAGELPDGCP------------LSDEVEDLICGMLAVEPSERLT----------LDGVLEHPW
 ||.| |                     .  . ..  .. . .   |            .|.|  ||| ..| ..|..||.           . . .|||
MYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPW

I
 
F
Kinase CAMK1c-S5_y.AA CAMKL 89-267 27 3.4e-38 119.38 In-house 98-297 (297) Show / Hide 
Range on Protein: 89-267
Range on HMM: 98-297/297
Sequence Identity: 27% (58 aa)

MVMELCGPS---LFHRLIKG----GPLDEEEAAKTIQRLAEALKGIHSSGIVHRDLKPENIFVKLDATAVHEVVIGDFGVAT--DD-----PKEMSQCCG
.|||.|.     ||....|     |...|.|| .  . . .|.. .|| ||||||.||||| .  .      . | ||| ..  ..      . .. .||
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCG

TGKYMAPEVTSCKGDARS--QSFYTAAIDVWALGVIAYELLRGY--------------KQSREIELLRAGELPDGCP--LSDEVEDLICGMLAVEPSERL
.  |||||. .      .  ....  ..|.|..||| | .. ||               . .. .  . |   .  .  .| ...||| .|| | |..| 
SPPYMAPEIFQ------GNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRP

TLDGVLEHPWI
|.. ...||| 
TIHQIMNHPWM
Kinase CAMK1c-S5_y.AA Ciliate-E2 89-267 24 7.1e-38 127.58 In-house 111-365 (365) Show / Hide 
Range on Protein: 89-267
Range on HMM: 111-365/365
Sequence Identity: 24% (65 aa)

MVMELC-GPSLFHRLI------------KGGPLDEEEAAKTIQRLAE---------------ALKGIHSSG-IVHRDLKPENIFVKLDATAVHEVVIGDF
.|||.| | .||....            . ....|.|... .. ...               ||. .|| . |.|||.|||||..         . | ||
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDF

GVATDDPKE------MSQC----------------------------CGTGKYMAPEVTSCKGDA--RSQSFYTAAIDVWALGVIAYELLRGYK-QSREI
| ...  ..      ..||                            |||  |||||. . |..     |  |. ..|.|.|||| ||.| |.      .
GLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---Q

ELLRAGELPDGCP------------------LSDEVEDLICG----MLAVEPSERLT-LDGVLEHPWI
.    ...   ||                  .|.|. |||      || ..|..|.|  . .|.|||.
QQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMK1c-S5_y.AA ULK 89-267 25 1.4e-30 104.01 In-house 97-329 (329) Show / Hide 
Range on Protein: 89-267
Range on HMM: 97-329/329
Sequence Identity: 25% (60 aa)

MVMELCGP-SLFHRLIKGGP----------LDEEEAAKTIQRLAEALKGIHSSGIVHRDLKPENIFVKLD--------ATAVHEVV--IGDFGVATD-DP
..||.|    |.. . | ..          | |.|| . .. .....| .|. .|.|||.||.|| .. .        . .. ..|  |.||| |   | 
IIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFAKHVDN

K------EMSQC-----CGTGKYMAPEVTSCKGDARSQSFYTAAIDVWALGVIAYELLRGY-----KQSREIELLRAGEL--------------PDGCP-
       .|..      |||  ||||.. . .|    . .|..  |.| ||.| ||.| |.        ..  |.   .|              |  .| 
DNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQG--EQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPK

------LSDEVEDLICGMLAVEPSERLTLDGVLEHPWI
      .|.|..||| .|| .....| . . ...|||.
DGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase CAMK1c-S5_y.AA CAMK1 89-216 40 1e-29 83.54 In-house 85-213 (276) Show / Hide 
Range on Protein: 89-216
Range on HMM: 85-213/276
Sequence Identity: 40% (54 aa)

MVMELC-GPSLFHRLIKGGPLDEEEAAKTIQRLAEALKGIHSSGIVHRDLKPENIFVKLDATAVHEVV--IGDFGVA--TDDPK-EMSQCCGTGKYMAPE
.||||. |  ||.| .. |   |..|..... ...|.. .|| |||||||||||.  . |    ....  | ||| .  .|.    |...|||  |.|||
LVMELVTGGELFDRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYY-DKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPE

VTSCKGDARSQSFYTAAIDVWALGVIAYELLRGY
|  ||       .|  |.|.|  ||| | || ||
VLECKK----DKPYDKACDMWSIGVITYILLCGY
Kinase CAMK1c-S5_y.AA DCAMKL 98-216 35 9.8e-29 86.08 In-house 102-216 (279) Show / Hide 
Range on Protein: 98-216
Range on HMM: 102-216/279
Sequence Identity: 35% (43 aa)

LFHRLIKGGPLDEEEAAKTIQRLAEALKGIHSSGIVHRDLKPENIFVKLDATAVHEVVIGDFGVATDDPK---EMSQCCGTGKYMAPEVTSCKGDARSQS
||  ... .   | .||  .  |..||| .|. .|||||.||||  |. .   . ..  .||| |.  ..    ..  |||  | |||. . .|      
LFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETG------

FYTAAIDVWALGVIAYELLRGY
 |   .|.||.||| | || |.
-YGCKVDIWAAGVILYILLCGF
Kinase CAMK1c-S5_y.AA Ciliate-E2-Unclassified 89-216 27 1.8e-27 92.39 In-house 98-267 (352) Show / Hide 
Range on Protein: 89-216
Range on HMM: 98-267/352
Sequence Identity: 27% (47 aa)

MVMELC------------------GPSLFHRLIKGGPLDEEEAA-----KTIQRLAEALKGIHSSG-IVHRDLKPENIFVKLDATAVHEVVIGDFGVAT-
.|||.|                  |  |||.. ..  ..|..|.     . .  . ..|. .|... |.|||.|||||... .     .. | ||| .  
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-NYYIKIIDFGISKK

--DD---------------PKEMSQCCGTGKYM----APEVTSCKGDARSQSFYTAAIDVWALGVIAYELLRGY
  ..               ...|...|||  ||    ||||   ..   | .    ..|.|.||||.||.| ||
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA---YKCDIWSLGVILYEMLFGY
Kinase CAMK1c-S5_y.AA MAPKAPK 20-216 29 1.6e-24 72.46 In-house 1-215 (292) Show / Hide 
Range on Protein: 20-216
Range on HMM: 1-215/292
Sequence Identity: 29% (64 aa)

YTRGERLGCGSQGQVFVLKGATS---YAGKMFRAG-----RDAGRELRLMSKLRGCAGVVSLAGFVKE-RSGGACYGTMVME-LCGPSLFHRLIK--GGP
 . .| || |. |.|   .   .   || |. .         | || .| ..  |.. .|..  . ..   . .|   .||| . | .||..  .   ..
KLWKEVLGEGIYGKVQTCVHKRTGQEYAVKILEDQPGHSRQKARREVELHWHCQGHPNIVQIIDWFENMYQFDKCF-YLVMECMEGGELFQHIQQRGHKH

LDEEEAAKTIQRLAEALKGIHSSGIVHRDLKPENIFVKLDATAVHEVVIGDFGVATD-------DPK----EMSQCCGTGKYMAPEVTSCKGDARSQSFY
  |.||.. ..  ..|..  || .| |||||||||  . | . .  | ..||| |         . .    |.   |.|  ||||||          ..|
FTEREASQIMKDICSAVDFLHSMNIAHRDLKPENILCT-DTNHNCPVKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFK---EAHTY

TAAIDVWALGVIAYELLRGY
    | | |||| | .| ||
DKSCDMWSLGVIMYIMLCGY
Kinase CAMK1c-S5_y.AA RSK 89-216 34 8.4e-22 76.71 In-house 78-209 (278) Show / Hide 
Range on Protein: 89-216
Range on HMM: 78-209/278
Sequence Identity: 34% (47 aa)

MVMELC-GPSLFHRLIKGGP---LDEEEAAKTIQRLAEALKGIHSSGIVHRDLKPENIFVKLDATAVHEVVIGDFGVATDDPKEMSQ----CCGTGKYMA
..||.| |. || .| | .    ..|.||.  .  .. |.. .|. ||.|||||||||    .     .... ||| .   . ...|     |.|  |||
LIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMA

PEVTSCKGDARSQSFYTAAIDVWALGVIAYELLRGY
||.     .|  |. ...| |.| |||. ||.| |.
PEMLK---RANQQGGHDKACDWWSLGVLMYEMLTGC
Kinase CAMK1c-S5_y.AA CAMK1 237-267 46 1.5e-13 35.66 In-house 245-276 (276) Show / Hide 
Range on Protein: 237-267
Range on HMM: 245-276/276
Sequence Identity: 46% (15 aa)

SDE-VEDLICGMLAVEPSERLTLDGVLEHPWI
||. . |.|..|| |.|..|.| . .|.||||
SDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CAMK1c-S5_y.AA MAPKAPK 237-267 48 1.6e-11 31.47 In-house 262-292 (292) Show / Hide 
Range on Protein: 237-267
Range on HMM: 262-292/292
Sequence Identity: 48% (15 aa)

SDEVEDLICGMLAVEPSERLTLDGVLEHPWI
|.|. |||  .| ..|..|||   |..||||
SEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase CAMK1c-S5_y.AA DCAMKL 237-267 45 1.2e-10 28.79 In-house 249-279 (279) Show / Hide 
Range on Protein: 237-267
Range on HMM: 249-279/279
Sequence Identity: 45% (14 aa)

SDEVEDLICGMLAVEPSERLTLDGVLEHPWI
|| ..|||  || |.|  | |   ...|||.
SDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CAMK1c-S5_y.AA TyrKc 20-267 22 2.6e-09 -72.01 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-267
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YTRGERLGCGSQGQVF--VLKGATSYAGKMFRAGRDAG---RELRLMSKL-RGCAGVVSLAGFVKERS------GGACYGTMVMELCGP-SLFHRLIKGG
 | |. ||.|  |.|.  ..|  .  | || ...       ||.|.|.||      .| | | . . .      .  .   .|||..   .| ..| | .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM---IVMEYMPHGDLKDYLRKHR

P-LDEEEAAKTIQRLAEALKGIHSSGIVHRDLKPENIFVKLDATAVHEVVIGDFGVATDDPKE--------MSQC----CGTG----KYMAPEVTSCKGD
| |  ..  .     |.    .|| ...||||   |. |. .      | |.||| . |   .        .       .| .    . ||||.      
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----

ARSQSFYTAAIDVWALGVIAYELL-RGYKQSRE-----------IELLRAGELPDGCPL---------SDEVEDLICGMLAVEPSERLTLDGVLEHPWI
    . .| . |||. ||  .|.. .| .   .           ||....|. ..  |          .||. ...    . .|..| |   .  |  .
--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CAMK1c-S5_y.AA Ciliate-E2-Unclassified 236-267 36 7.6e-09 26.84 In-house 317-352 (352) Show / Hide 
Range on Protein: 236-267
Range on HMM: 317-352/352
Sequence Identity: 36% (13 aa)

LSDEVEDLIC----GMLAVEPSERLTLDGVLEHPWI
.|.|..|.|      || . |..|.|.. .|.|||.
WSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CAMK1c-S5_y.AA RSK 236-267 37 1.8e-08 27.47 In-house 242-278 (278) Show / Hide 
Range on Protein: 236-267
Range on HMM: 242-278/278
Sequence Identity: 37% (14 aa)

LSDEVEDLICGMLAVEPSERLT-----LDGVLEHPWI
||.|  ||| .|| ..|. ||.     .. ...|||.
LSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF