Gene HisK_q (S.moellendorffii)
HisK_q
Species: S.moellendorffii
Alias: HisK_q
External Links:
Annotation:
Sequence
Protein domains of HisK_q.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| HisKA | HisK_q.AA | HisKA | 239-308 | 23 | 9.9e-07 | 26.45 | Pfam | 1-69 (69) | Show / Hide |
Range on Protein: 239-308 Range on HMM: 1-69/69 Sequence Identity: 23% (17 aa) AKQQFMAYVFHNIRVPFNAIVLGLGHMRASASGDDSSSGE--LDLVQLMLDCAETMTNVLDDVTDMGNWEEG ||.||.|.. | .| | .|| . . ... ..| .. . .... ....|. | . ..|. |. |.| AKRQFLANMSHELRTPLTAIRGYAELLQD---YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG |
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| HisKA | HisK_q.AA | HisKA | 239-308 | 19 | 2.9e-05 | 23.5 | SMART | 1-89 (89) | Show / Hide |
Range on Protein: 239-308 Range on HMM: 1-89/89 Sequence Identity: 19% (17 aa) AKQQFMAYVFHNIRVPFNAIVLGLGHMRASA-------SGDDSSSGE------------LDLVQLMLDCAETMTNVLDDVTDMGNWEEG ||.||.|.. | .| | .|| . . ..... ..| .. .... ....|. | . ..|. |. |.| AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG |
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| HATPase_c | HisK_q.AA | HATPase_c | 360-491 | 26 | 1.7e-23 | 84.05 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 360-491
Range on HMM: 1-120/120
Sequence Identity: 26% (39 aa)
GDKHRTVQTLGNFLSNAVKFTPTGGKLDLEIKCQELDGVPVSNSKGFETDELEHKSLELFIAVNDSGAGISL------DDQDRLFE-------ADSFISS
|| | .| . |...||.|.||.||....... .. .. | | |.| ||. .|..|.|| .
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---------------------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD------
PWVQKAGVSG----LGLSVAKRFIEQIGGQIGVRSR-DQGSTFFFSAPFQ
..| |||....|..|| ||.| |.|. ..|.|| | |..
--SR-RKYGGGLTGLGLYICRRIVEQHGGTIWVESEPGGGTTFTFTLPLE
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| HATPase_c | HisK_q.AA | HATPase_c | 360-492 | 26 | 1.9e-22 | 81.79 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 360-492
Range on HMM: 1-130/130
Sequence Identity: 26% (43 aa)
GDKHRTVQTLGNFLSNAVKFTPT-------------GGKLDLEIKCQELDGVPVSNSKGFETDELEHKSLELFIAVNDSGAGISL------DDQDRLFEA
|| | | | | |.||.|.||. ||....... | | |.| ||. .|..|.||.
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------------------------RITVEDNGPGIPPEMHKSIEDIPRIFEP
DSFISS--------PWVQKAGV--SGLGLSVAKRFIEQIGGQIGVRSRDQGSTFFFSAPFQL
.. ..| | .|||||..||..|| ||.| |. .|| |. | ..
FYRTDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE-----TTFTFTLPLER
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| Kinase | HisK_q.AA | HisK | 360-486 | 21 | 3.3e-12 | 40.68 | In-house | 1-159 (164) | Show / Hide |
Range on Protein: 360-486 Range on HMM: 1-159/164 Sequence Identity: 21% (35 aa) GDKHRTVQTLGNFLSNAVKFTPTGG-----KLDLEIKCQELDGVPVSNSKGFETDELEHKSLE-------------LFIAVNDSGAGISLDDQDRLFEAD |. | | | |..|||.||| || . ....... . . . | . ... .... . | | |.| |.. ..| .|.. SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNN-I---KY-N--SIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMF S------------FISSPWVQKAGVSGLGLSVAKRFIEQIG--------GQIGVRSR-DQGSTFFF . |. . .. ||||..........| ..| | | ..|||| | GNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSF |
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| REC | HisK_q.AA | REC | 552-664 | 23 | 6.7e-31 | 109.89 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 552-664 Range on HMM: 1-150/150 Sequence Identity: 23% (37 aa) RKVLLVEDT----RINRIILR------KVLQNLNLQ--------CDEAENGQ-------IAVDLHRQGK------------SYDLVLMDKEMP------- ..|.|.| ..| .|| . |. .. . .||| .|. |..| .... .||..|| .|| MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG VMDGHEATRALRMMGVKTPIVALTGNALQSDKELFFEAGVNEFQTKPLSRDKLIQLL ||| |..|..| ||..||... .|.. .|||.. . ||| ... |.. . GMDGIELCRRIR------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
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| Response_reg | HisK_q.AA | Response_reg | 554-665 | 31 | 2.6e-27 | 100.41 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 554-665 Range on HMM: 1-115/115 Sequence Identity: 31% (37 aa) VLLVEDTRINRIILRKVLQ-NLNL-QCDEAENGQIAVDLHRQGKSYDLVLMDKEMPVMDGHEATRAL-RMMG-VKTPIVALTGNALQSDKELFFEAGVNE ||.|.| ...| .||. |. . ..||..|. |... .... .||..|| .|| ||| |..| . | . .|||...|... .|.. ..|| | VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-PDLIIMDINMPGMDGLELCRRIRRQHPHPQTPIIMCTAHGDEDDAVEALQAGAND FQTKPLSRDKLIQLLA . ||| ..|.|.. .. YITKPFDPDELHAAIR |
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