Gene RSK-p4-1 (S.moellendorffii)

RSK-p4-1

Species: S.moellendorffii
Alias: RSK-p4-1
External Links:
Annotation:

Classification

Group: AGC
Family: RSK
Subfamily: RSK-p4

Sequence

Name Sequence Type Origin Length Description Download
RSK-p4-1.AA Protein None 446 None Fasta, JSON
RSK-p4-1.NA RNA None 1341 None Fasta, JSON
RSK-p4-1.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of RSK-p4-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RSK-p4-1.AA AGC 115-400 28 2.2e-138 360.18 In-house 1-395 (395) Show / Hide 
Range on Protein: 115-400
Range on HMM: 1-395/395
Sequence Identity: 28% (119 aa)

FKLMQRVGGGDIGIVFLAELVNS----SSSYRFAVKIMDKEH-LVKRN--KLSRIATE------------RRILEMLD----------HPFLPT-LYGSF
|..   .| |  | |.|.. ...    ..   .|.|...|.|  |...  .. .. ||            |.|||...          |||.   |. ||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETSEH--ACFVMDFCP---------GG-DLHKLRQRQ-PNKRFDEETVRFYAAE-------VLLALEYLHM-MGVVYRD-LKPENVLVRDDGHIMLTDFD
.. .|   .|||...|         || .|.   | .  ..|||||..||||||       ..|||||||  ||...|| |||||.|  .||||.|||| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSLE----------------------------FDAAPSMLKPHRLYGLRSPSMSPFLSSHLR--------------SMSFVG--THEYLAPEIIAGGGHG
|. |                            .|  . .               |    . .                .|.|  |.||.||||.    .|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMD--T-N-----------K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YG

SAVDWWT--LGIFIYELLYGHTPFKGTNND----------ATLMNAF------SKSLLFPSD--------VEVSLFAKDLIKSLLAKDPKRRLGFAR---
 |.|||.  ||...||.|.|..|| | |..           .  .        .. . ||..        ...|  |||||| || |||..|||  .   
KACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDF

---GAADIKTHNFF
   || .|| | .|
GDKGAEEIKNHPWF
Kinase RSK-p4-1.AA RSK-Unclassified 115-400 41 7.79999999999e-114 359.06 In-house 1-283 (283) Show / Hide 
Range on Protein: 115-400
Range on HMM: 1-283/283
Sequence Identity: 41% (120 aa)

FKLMQRVGGGDIGIVFLAELVNSSSSYRFAVKIMDKEHLVKRNKLSRIATERRILEMLDHPFLPTLYGSFETSEHACFVMDFCPGGDLHKLRQRQPNKRF
|     .| ||.| |.| .  ..   |  | |.. |. ....||  .. ||. |. . .|||  ||| || |.     .|..|.|||. .  |    |.|
FIKHRLIGQGDFGKVYLVRKKDTQQIY--AMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCF

DEETVRFYAAEVLLALEYLHMMGVVYRDLKPENVLVRDDGHIMLTDFDLSLEF-DAAPSMLKPHRLYGLRSPSMSPFLSSHLRSMSFVGTHEYLAPEIIA
 |. |||||.|| .||||||  ...||||||.|..   .||.|||||||| .  |.   ..|      .        ..   |  ||.|| ||||||.| 
CEDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKI---CDHGFRTNSFCGTEEYLAPEMIR

GGGHGSAVDWWTLGIFIYELLYGHTPFKGTNNDATLMNAFSKSLLFPSDVEVSLFAKDLIKSLLAKDPKRRLGFARG-AADIKTHNFF
. ||. ||||||||| .||.| | .|..| | . |  |   . . || | ..|  ..|||| || . | .|||  .| |.||| | ||
RCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase RSK-p4-1.AA RSK 118-400 34 3.2e-91 309.38 In-house 1-278 (278) Show / Hide 
Range on Protein: 118-400
Range on HMM: 1-278/278
Sequence Identity: 34% (104 aa)

MQRVGGGDIGIVFLAELV-NSSSSYRFAVKIMDKEHLVKRNK-LSRIATERRILEMLD-HPFLPTLYGSFETSEHACFVMDFCPGGDLHKLRQRQPNK-R
..  | |. | |||   . .. .   .|.|. .|  .|.|.| . .  |||.|||.   |||. ||. .|.| ..   .|..|.||.| .  |..  .  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDEETVRFYAAEVLLALEYLHMMGVVYRDLKPENVLVRD---DGHIMLTDFDLSLEFDAAPSMLKPHRLYGLRSPSMSPFLSSHLRSMSFVGTHEYLAPE
|.|....||.||. ||.|.||  |...|||||||.|  |   .|||.||||... .|                       ..   . |.|..|.||.|||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF----------------------RCDHNQWTMTFCYTIEYMAPE

IIA----GGGHGSAVDWWTLGIFIYELLYGHTPFKG---TNNDATLMNAFSKS--LLFPSDVEVSLFAKDLIKSLLAKDPKRRLGF-ARGAADIKTHNFF
...    .|||. |.|||.||. .||.| |..||.|    | . .. .  ..   | .| . ..|  |||||. .| .||..|||   ..|..|| | .|
MLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase RSK-p4-1.AA AktR 143-400 39 2e-89 303.41 In-house 28-268 (268) Show / Hide 
Range on Protein: 143-400
Range on HMM: 28-268/268
Sequence Identity: 39% (103 aa)

FAVKIMDKEHLVKRNKLSRIATERRILE-MLDHPFLPTLYGSFETSEHACFVMDFCPGGDLHKLRQRQPNKRFDEETVRFYAAEVLLALEYLHMM-GVVY
.| |. .|.....||. ... ||| |.| . .|||.  |. .|.| |.  |.|..||||.|    ..  .|.|.||..|||.|..||||||||    ..|
YAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKK--KKKFSEEQARFYFAQILLALEYLHQHMNIIY

RDLKPENVLVRDDGHIMLTDFDLSLEFDAAPSMLKPHRLYGLRSPSMSPFLSSHLRSMSFVGTHEYLAPEIIAG-GGHGSAVDWWTLGIFIYELLYGHTP
||||||| |   |||. .||| ||                      . .  .   .  ||.||.||.|||.|    ||. .||||..||||||...|..|
RDLKPENILLDEDGHVKITDFGLSK---------------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPP

FKGTNNDATLMNAFSKS-LLFPSDVEVSLFAKDLIK-SLLAKDPKRRLG-FARGAADIKTHNFF
|   |.   . .  .|  . ||  ...| ..||||.  || |.|. ||| .. |. .|| | .|
FYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase RSK-p4-1.AA S_TKc 115-400 27 4.3e-87 296.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 115-400
Range on HMM: 1-231/231
Sequence Identity: 27% (82 aa)

FKLMQRVGGGDIGIVFLAELVNSSSSYRFAVKIMDKEHLVKRNKLSRIATERRILEMLDHPFLPTLYGSFETSEHACFVMDFCPG--GDLHKLRQRQPNK
..... .| |  | |...  ..  .  ..|.||..           .|  |..||.. .||.. .||..|.. .| ..||..|.|  |||... .... .
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

R----FDEETVRFYAAEVLLALEYLHMMGVVYRDLKPENVLVRDDGHIMLTDFDLSLEFDAAPSMLKPHRLYGLRSPSMSPFLSSHLRSMSFVGTHEYLA
.    |.| ..|||......||||.| .|...|||||||.|. .  ||...|| |. ..                              ..|.|| .|.|
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------TTFCGTPWYMA

PEIIAGGGHGS-AVDWWTLGIFIYELLYGHTPFKGTNNDATLMNAFSKSLLFPSDVEVSLFAKDLIKSLLAKDPKRRLGFARGAA---DIKTHNFF
||..   |.|  ..||| .|. .||.|.| .||    .......              |  |||.|. .| |||..|..     .   ||| | .|
PEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RSK-p4-1.AA Pkinase 115-400 28 1.1e-76 265.92 Pfam 1-293 (293) Show / Hide 
Range on Protein: 115-400
Range on HMM: 1-293/293
Sequence Identity: 28% (92 aa)

FKLMQRVGGGDIGIVFLAELVNSSSSYRFAVKIMDKEHLVKRNKLSRIA-TERRILEMLDHPFLPTLYGSFETSEHACFVMDFCPGG----DLHKLRQRQ
... ...| |  | |...  ....   ..||||..|.|  .  . ...  .| .|. .|.||.  .||..||.. | ..||..|.||    ||. . ...
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

PNKRF--DEETVRFYAAEVLLALEYLHMMGVVYRDLKPENVLVRDDGHI----MLTDFDLSLEFDAAPSMLKPHRLYGLRSPSMSPFLSSHLRSMSFVGT
 ...|  .|....||. ..| .|||.| ||...|||||||.|. ..|||     ..|| |.  ||                      . .    ..|.||
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------------------Y-NNS-MTTFCGT

HEYLAPEIIA-GGGHGSAVDWWTLGIFIYELLYGHTPFKGT------NNDATLMNAFSKSLLFPSDVEVS-------------------LFAKDLIKSLL
 .|.|||.|  | ..|..||.| .|. .||.| |..||.|       . .. . .  .. | |... . |                     .||.||..|
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

AKDPKRRLGFARGAADIKTHNFF
.||||.|..    |..|. | .|
CKDPKKRPT----AEQILQHPWF
Kinase RSK-p4-1.AA Ciliate-E2 115-400 23 4.2e-67 229.23 In-house 1-365 (365) Show / Hide 
Range on Protein: 115-400
Range on HMM: 1-365/365
Sequence Identity: 23% (93 aa)

FKLMQRVGGGDIGIVFLAELVNSSSSY---------------------RFAVKIMDKEHLVKRNKLSRIA----------TERRILEMLDHPFLPTLYGS
.|. .  | |  |.|....  .    .                      .|.||| |  .   ..  .|            |..||| |.||..  .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--TSEHACFVMDFCPGGDLHKLRQRQPNKR---------FDEETVR---------------FYAAEVLLALEYLHMMG-VVYRDLKPENVLVRDDGHI
|.  . ..  .||..| |||| .. . .. ||         |.|. ..               ||.|...|||||||  . ...||.||||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

MLTDFDLSLEFD---------AAPSMLKPHRLYGLRSPS-MSPFLSSHL-----RSMSFVGTHEYLAPEIIAGGG---------HGSAVDWWTLGIFIYE
 ..|| || ..|             ...  . .  |.|. |.      .        ...|| .|.||||. |..         .. ..|.| ||. .||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD------QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

LLYGHTPFKGTNNDATLMNAFSK-SLLFP----------------SDVEVSLFAKDLIKS----LLAKDPKRRLGFARGAADIKTHNFF
.|.| .||         ..   .  . ||                |  ..|. .|||||     .| |||. |..   |. .|. | .|
MLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT---GWEQILNHPWF
Kinase RSK-p4-1.AA Akt 143-261 46 1.7e-52 166.08 In-house 28-145 (264) Show / Hide 
Range on Protein: 143-261
Range on HMM: 28-145/264
Sequence Identity: 46% (56 aa)

FAVKIMDKEHLVKRNKLSRIATERRILEMLDHPFLPTLYGSFETSEHACFVMDFCPGGDLHKLRQRQPNKRFDEETVRFYAAEVLLALEYLHMMGVVYRD
.| |.  |......|..  . |||.||.. .|||.  |. || |... .||||.|.||.|  . ||.  .||.|.. |||.||. ||.|.|| ....|||
YAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRK--RRFSEDRARFYCAEIILAIEHLHSKNIIYRD

-LKPENVLVRDDGHIMLTDF
 |||||.|.  |||| ||||
YLKPENILMDKDGHICLTDF
Kinase RSK-p4-1.AA SGK 115-264 35 1.1e-47 145.0 In-house 1-172 (283) Show / Hide 
Range on Protein: 115-264
Range on HMM: 1-172/283
Sequence Identity: 35% (61 aa)

FKLMQRVGGGDIGIVFLAELVNS----------------SSSYRFAVKIMDKEHLV-------KRNKLSRIATER-RILEMLDHPFLPTLYGSFETSEHA
|.... .| |  | |.... .                  |    .|.|.  |.| .       |...   | .||  ||  . |||.  |  .| | .  
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

CFVMDFCPGGDLHKLRQRQPNKRFDEETVRFYAAEVLLALEYLHMMGVVYRDLKPENVLVRDDGHIMLTDFDLS
 ||||.  ||..    ||   |.| |  .||||||. .||||||   ..||||||||.|  ..||. |||| |.
YFVMDYVNGGEMFYHLQRE--KHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLC
Kinase RSK-p4-1.AA PKA 115-261 36 1.1e-43 151.51 In-house 1-145 (263) Show / Hide 
Range on Protein: 115-261
Range on HMM: 1-145/263
Sequence Identity: 36% (54 aa)

FKLMQRVGGGDIGIVFLAELVNSSSSYRFAVKIMDKEHLVKRNKLSRIATERRILEMLDHPFLPT-LYGSFETSEHACFVMDFCPGGDLHKLRQRQPNKR
|...| .| |  | | |.   .|   | .| |...|.  |...   .. .|..||  ..|||. . .|..| .. .  .||...|||.. .  ..  ..|
FEIIQTLGTGSFGRVMLCRHKHSG-NY-YAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRK--SGR

FDEETVRFYAA-EVLLALEYLHMMGVVYRDLKPENVLVRDDGHIMLTDF
|.. . .|||| .. ||||||| .  .|||||||| |  ..||| .|||
FSNPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDF
Kinase RSK-p4-1.AA MAST 115-264 36 2.3e-41 123.7 In-house 1-149 (337) Show / Hide 
Range on Protein: 115-264
Range on HMM: 1-149/337
Sequence Identity: 36% (56 aa)

FKLMQRVGGGDIGIVFLAELVNSSSSYRFAVKIMDKEHLVKRNKLSRIATERRILEMLDHPFLPTLYGSFET--SEHACFVMDFCPGGDLHKLRQRQPNK
|.    .. |  | |.|..  . ..  ||| |....  . ..| .  .  || ||.|.. ||   .. ||.|   .. |.||..  |||  .|  |  . 
FEFIKCISKGAYGAVYLVK--HKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASL-LRMYGN

RFDEETVRFYAAEVLLALEYLHMMGVVYRDLKPENVLVRDDGHIMLTDFDLS
...|. ...| ||  |.||||| .| | |||||.|.|   .||| |||| ||
CMPEWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase RSK-p4-1.AA MAST 115-264 38 1.7e-40 128.07 In-house 1-146 (334) Show / Hide 
Range on Protein: 115-264
Range on HMM: 1-146/334
Sequence Identity: 38% (58 aa)

FKLMQRVGGGDIGIVFLAELVNSSSSYRFAVKIMDKEHLVKRNKLSRIATERRILEMLDHPFLPTLYGSFETSEHACFVMDFCPGGDLHKLRQRQPNKRF
|.    .. |  | |.|..  . ..  |||.|...|  . ..| ..   .|| ||.|.. ||   .. ||.| .. |.||..  |||. .|  .  . .|
FEFIKPISKGAYGKVYLVK--HKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASL-LHMYG-YF

DEETVRFYAAEVLLALEYLHMMGVVYRDLKPENVLVRDDGHIMLTDFDLS
||.....| ||. |.||||| .| | |||||.|.|   .||| |||| ||
DEWMAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase RSK-p4-1.AA MAST 301-400 40 5.7e-40 119.35 In-house 229-337 (337) Show / Hide 
Range on Protein: 301-400
Range on HMM: 229-337/337
Sequence Identity: 40% (45 aa)

VGTHEYLAPEIIAGGG-HGSAVDWWTLGIFIYELLYGHTPFKGTNNDA-TLMNAFS--KSLLFPSD------VEVSLFAKDLIKSLLAKDPKRRLGFARG
.|| .|.|||.| | | .| .|||| .|| .||.| | .|| | .    .  |  .  . . .|..       ..|  |.|||| ||...|| |||.  |
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGAN-G

AADIKTHNFF
|..||.| ||
ADEIKQHPFF
Kinase RSK-p4-1.AA SGK 299-400 45 7.3e-40 120.46 In-house 184-283 (283) Show / Hide 
Range on Protein: 299-400
Range on HMM: 184-283/283
Sequence Identity: 45% (46 aa)

SFVGTHEYLAPEIIAGGGHGSAVDWWTLGIFIYELLYGHTPFKGTNNDATLMNAFSKSLLFPSDVEVSLFAKDLIKSLLAKDPKRRLGFARGAADIKTHN
.| || ||||||.... .|. .|||| ||.. ||..||  ||   |      |  .. | .|    .|  |.|||. ||.|||| ||| .|....|| | 
TFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPP--QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHP

FF
||
FF
Kinase RSK-p4-1.AA Akt 298-400 43 1.3e-37 117.73 In-house 160-264 (264) Show / Hide 
Range on Protein: 298-400
Range on HMM: 160-264/264
Sequence Identity: 43% (46 aa)

MSFVGTHEYLAPEIIAGGGHGSAVDWWT-LGIFIYELLYGHTPFKGTNNDATLMNAFSKSLLFPSDVEVSLFAKDLIKSLLAKDPKRRLG-FARGAADIK
..| || |||||||. | ||. |||||. ||...||...|  ||   ...    . ... . ||    .|  .||||..|| ||||.||| .  .| .||
KTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIK

THNFF
 | .|
RHPWF
Kinase RSK-p4-1.AA MAST 301-400 39 1.2e-35 112.14 In-house 225-334 (334) Show / Hide 
Range on Protein: 301-400
Range on HMM: 225-334/334
Sequence Identity: 39% (43 aa)

VGTHEYLAPEIIAGGG-HGSAVDWWTLGIFIYELLYGHTPFKGTNNDATLMNAFSKS---LLFPSD------VEVSLFAKDLIKSLLAKDPKRRLGFARG
.|| .|.|||.| | | || .|||| .|| .||.| | .|| . . . .  |  ...     .| .       . |  |.|||. ||. ||. |||.  |
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

AADIKTHNFF
|...|.| ||
ADEVKQHPFF
Kinase RSK-p4-1.AA PKA 302-400 43 4.6e-35 122.81 In-house 160-263 (263) Show / Hide 
Range on Protein: 302-400
Range on HMM: 160-263/263
Sequence Identity: 43% (45 aa)

GTHEYLAPEIIAGG-GHGSAVDWWTLGIFIYELLYGHTPFKGT--NNDATLMNAFSKSLLFPSDVEVSL-FAKDLIKSLLAKDPKRRLGFAR-GAADIKT
|| |||||||| .  ||| .||||.||| |||.| |..||  .  .  ..     .  . ||. . . . . |||||.||..|...|.|  . |. |||.
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKN

HNFF
| .|
HKWF
Kinase RSK-p4-1.AA TyrKc 115-394 19 6.3e-13 -13.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 115-394
Range on HMM: 1-280/280
Sequence Identity: 19% (61 aa)

FKLMQRVGGGDIGIVFLAELVNSSSSYRFAVKIMDKEHLVKRNKLSRIATERRILEML--DHPFLPTLYGSFETS-------EHACFVMDFCPGGDLHKL
 .| .  | |  |.|.....      .  ||| . ...      .  .  | ||. .|  .|| .  |||   ..       |  . || ..|.|||.. 
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

RQRQPNKRFDEETVRFYAAEVLLALEYLHMMGVVYRDLKPENVLVRDDGHIMLTDFDLSLEFDAA------PSMLKPHRLYGLR--SPSMSPFLSSHLRS
 ..  .| .  ..   ..  .    |||| .... |||   |.|| .....  .|| || . .         .. ..    | .   |         .| 
LRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP---------IR-

MSFVGTHEYLAPEIIAGGGHGSAVDWWTLGIFIYELL-YGHTPFKG-----TNNDATLMNAFSKSLLFPSDV-------EVSLFAKDLIKSLLAKDPKRR
         .||| |  |   .. | |  |. ..|.. || .|  |      .|.  . .  .   . . .        . .    ...|.  . ||. |
--------WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDR

LGFARGAADI
  |.    ..
PTFSEIHECF
Kinase RSK-p4-1.AA Pkinase_Tyr 115-243 23 5e-06 20.99 Pfam 1-137 (270) Show / Hide 
Range on Protein: 115-243
Range on HMM: 1-137/270
Sequence Identity: 23% (32 aa)

FKLMQRVGGGDIGIVFLAELV--NSSSSYRFAVKIMDKEHLVKRN-KLSRIATERRILEML-DHPFLPTLYGSFE-TSEH--ACFVMDFCPGGDLHK-LR
 ....  | |  | |.....    ..  .  |||.. ||.  ... ..     | .|.  | .|| .  |||     .|.   . || ..|.|||.. ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

QR-QPNKRFDEETVRFYAAEVLLALEYLHMMGVVYRDL
..  ...... ..   .....  ..|||. .. . |||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL