Gene NDR1_b (S.moellendorffii)
NDR1_b
Species: S.moellendorffii
Alias: NDR1_b
External Links:
Annotation:
Sequence
Protein domains of NDR1_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | NDR1_b.AA | NDR | 131-433 | 47 | 1.2e-181 | 565.73 | In-house | 1-350 (350) | Show / Hide |
Range on Protein: 131-433 Range on HMM: 1-350/350 Sequence Identity: 47% (166 aa) FELLTIIGRGAFGEVRLCREKRSGQVYAMKKLQKSEMLRRGQ-ASATAERNLLAEVD--SNCIVKLFCSFQDDEYLYLIMEYLPGGDMMT---LLMRKDT || ..|||.||||||.|.|.| .|..||||.. ||||... | |. ||| .||.| .. .|||..||||. ||||.|||.||||||| |||..|. FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI LTEDEARFYVGQAILAIESIHRHNYIHRDIKPDNLLLDKNGHMKLSDFGLCKP---------------------LDCSNLPALYENEPGIEEKIKDALTF .|||.|||| ..||||.|. .||||||||||.|.|| || ||.|||||. . .. .|.| .... . . .. FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN EALKSPARRRTQQEQLLH-----------WQRNRRMLAYSTVGTPDYIAPEVLLK-KGYGMECDWWSLGAIMYEMLVGYPPFYSDEPMSTCRKIVNWRMH .. .. .. |.. |..||| |||||||||||.||||... .||...|||||||.||||||||||||.||.| ||.|| ||. SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT L-----KFPEEAKLSAEAKDFISRLIC-DVEHRLGT--RGVHELKGHSWF . ||.||.|| ||.| | ||.| | .|||| ||.| | |..| WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF |
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Kinase | NDR1_b.AA | AGC | 131-433 | 30 | 2.7e-167 | 436.64 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 131-433 Range on HMM: 1-395/395 Sequence Identity: 30% (133 aa) FELLTIIGRGAFGEVRLCREK------RSGQVYAMKKLQKSE--------MLRRGQAS--------ATAERNLLAEVD----------SNCIVK-LFCSF ||.|..||.|.||.|.|.|.| .|..||||.|.|.. |... .. .||| |.... . ||| |..|| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QDDEY--LYLIMEYLP---------GG-DMMTLLM---RKDTLTEDEARFYVGQ-------AILAIESIHR-HNYIHRD-IKPDNLLLDKNGHMKLSDFG ||... ||..|||.| || .... |. .. ...|..|||| . .||.|..|. ...|||| .||.|.|||..|| ||.||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LCKPLDCS---------------------------NLPALYENEPGIEEKIKDALTFEALKSPARRRTQQEQLLHWQRNR-----------RMLAYSTVG ||| . . | . . . .||||. | .... .| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTN--------------------------------K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCG --TPDYIAPEVLLKKGYGMECDWWS--LGAIMYEMLVGYPPFYSDE----------PMSTCRKIV------NWRMHLKFP------EEAKLSAEAKDFIS ||.|.|||.| || .||||| ||..|||||.||||||.|. || . || ||. .. || |. ..| ||||.|. PCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIK RLIC-DVEHRLGTR-------GVHELKGHSWF .|.| | |.|||.. |. |.| | || KLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | NDR1_b.AA | S_TKc | 131-433 | 32 | 1.4e-99 | 338.01 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 131-433 Range on HMM: 1-231/231 Sequence Identity: 32% (103 aa) FELLTIIGRGAFGEVRLCREKRSGQVYAMKKLQKSEMLRRGQASATAERNLLAEVDSNCIVKLFCSFQDDEYLYLIMEYLPG--GDMMTLLMRKDT---- .|.| .||.||||.|..||.|..|...|.|.. .. |...| . . ||||. .||| ..||..|||..| ||..... .. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --LTEDEARFYVGQAILAIESIHRHNYIHRDIKPDNLLLDKNGHMKLSDFGLCKPLDCSNLPALYENEPGIEEKIKDALTFEALKSPARRRTQQEQLLHW ..| .||||. | ..|.| .|.|. ||||.||.|.|||. | |..||||.. | FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------- QRNRRMLAYSTVGTPDYIAPEVLLKKGYGM-ECDWWSLGAIMYEMLVGYPPFYSDEPMSTCRKIVNWRMHLKFPEEAKLSAEAKDFISRLIC-DVEHRLG .. .|||.|.||||| ||| .|||||.| |.||||.|||||. ... . .||. | ||||||... . | |.|.. --------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPT TRGVHE----LKGHSWF . . | | || A-EALQDEWDIKCHPWF |
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Kinase | NDR1_b.AA | DMPK | 131-275 | 51 | 4.2e-98 | 242.89 | In-house | 1-147 (270) | Show / Hide |
Range on Protein: 131-275 Range on HMM: 1-147/270 Sequence Identity: 51% (76 aa) FELLTIIGRGAFGEVRLCREKRSGQVYAMKKLQKSEMLRRGQASATA-ERNLLAEVDSNCIVKLFCSFQDDEYLYLIMEYLPGGDMMTLLMRKD-TLTED || |..||||.|||| . |.|....|||||.. | ||| | . . ||. .. .| |..|.. |||..|||..||| ||||. ||. | . . || FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED EARFYVGQAILAIESIHRHNYIHRDIKPDNLLLDKNGHMKLSDFGLC ||||. .||| |||. |.|||||||| |||..|| || ||| | MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSC |
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Kinase | NDR1_b.AA | RSK | 131-433 | 32 | 3.1e-96 | 326.04 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 131-433 Range on HMM: 1-278/278 Sequence Identity: 32% (105 aa) FELLTIIGRGAFGEVRLCREKRSGQVYAMKKLQKSEMLRRG--QASATAERNLLAEVD-SNCIVKLFCSFQDDEYLYLIMEYLPGGDMMTLLMRKDT--- ..|. .| |.. .| |. . .||.|||| |.|... .| .. . .||| |... . ||.|. .||....|||||||..||.. | | .. . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LTEDEARFYVGQAILAIESIHRHNYIHRDIKPDNLLLDK---NGHMKLSDFGLCKPLDCSNLPALYENEPGIEEKIKDALTFEALKSPARRRTQQEQLLH ..||||.|| . .||.| .| . ||||.||.| |.| .|| ||.|||.|| . FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF------------------------------------------- WQRNR-RMLAYSTVGTPDYIAPEVLL----KKGYGMECDWWSLGAIMYEMLVGYPPFYS---DEPMSTCRKIVNWRMHLKFPEEAKLSAEAKDFISRLIC |.. .... ..| .|.|||.| ..|.. |||||||..|||||.|.|||.. . . . ..| . . |..|. ..||.||||.|... . --RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLH -DVEHRLG--TRGVHELKGHSWF | . ||| ... |.| |.|| RDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | NDR1_b.AA | AktR | 131-433 | 35 | 4.6e-96 | 325.44 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 131-433 Range on HMM: 1-268/268 Sequence Identity: 35% (112 aa) FELLTIIGRGAFGEVRLCREK-RSGQVYAMKKLQKSEMLRRGQASAT-AERNLLA-EVDSNCIVKLFCSFQDDEYLYLIMEYLPGGDMMTLLMRKDTLTE |... ..|.||||.| |...| ....|||| . |... .| |...| ||| .. ... . ||||. .||..|.|..|||| |||.. . | .| ...| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE DEARFYVGQAILAIESIHRH-NYIHRDIKPDNLLLDKNGHMKLSDFGLCKPLDCSNLPALYENEPGIEEKIKDALTFEALKSPARRRTQQEQLLHWQRNR ..|||| | .||.| | | | | ||.||.|.|||..|| |..|||| | | .. . EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-------------------------------------------LQFMMHY RMLAYSTVGTPDYIAPEVLLK-KGYGMECDWWSLGAIMYEMLVGYPPFYSDEPMSTCRKIVNWRMHLKFPEEAKLSAEAKDFISR--LICDVEHRLG--T . .||| .||| |.|||...| ||.. .|||..|. |||..|.||||.. || . . .|||. ...| ..||.| | | . ..||| . DEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYC RGVHELKGHSWF | |.| | || NGWEEIKSHPWF |
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Kinase | NDR1_b.AA | MAST | 131-276 | 38 | 6e-68 | 206.45 | In-house | 1-150 (337) | Show / Hide |
Range on Protein: 131-276 Range on HMM: 1-150/337 Sequence Identity: 38% (57 aa) FELLTIIGRGAFGEVRLCREKRSGQVYAMKKLQKSEMLRR-GQASATAERNLLAEVDSNCIVKLFCSFQD--DEYLYLIMEYLPGGDMMTLLMRKD-TLT || . .|..||.| | | . |.... .|||.. .. .... . .. .||| |.... . .||.|.||| ..||...|||. ||| .|| .. FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP EDEARFYVGQAILAIESIHRHNYIHRDIKPDNLLLDKNGHMKLSDFGLCK |..|..|. . .|..| .| . .|||.||||.|.|.||| || |||| | EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSK |
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Kinase | NDR1_b.AA | MAST | 131-276 | 42 | 1.7e-66 | 213.24 | In-house | 1-147 (334) | Show / Hide |
Range on Protein: 131-276 Range on HMM: 1-147/334 Sequence Identity: 42% (62 aa) FELLTIIGRGAFGEVRLCREKRSGQVYAMKKLQKSEMLRR-GQASATAERNLLAEVDSNCIVKLFCSFQDDEYLYLIMEYLPGGDMMTLLMRKDTLTEDE || .|..||.| | | . |.... .|||.. ||.|... . . .||| ||..... .||.|.||| ..||...|||. ||| .|| .. |. FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM ARFYVGQAILAIESIHRHNYIHRDIKPDNLLLDKNGHMKLSDFGLCK |..|. . .|..| .|.| .|||.||||.|.|.||| || |||| | AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSK |
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Kinase | NDR1_b.AA | DMPK | 334-433 | 51 | 9.2e-65 | 158.56 | In-house | 162-270 (270) | Show / Hide |
Range on Protein: 334-433 Range on HMM: 162-270/270 Sequence Identity: 51% (56 aa) VGTPDYIAPEVL--LKKG----YGMECDWWSLGAIMYEMLVGYPPFYSDEPMSTCRKIVNW-RMHLKFPEEAK--LSAEAKDFISRLICDVEHRLGTRGV |||||||.|||| . . || ||||||.| .|||||.| ||| | .| ||.| . ||.||.. | .|.||||.| .|.|| |.||| |. VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGY HELKGHSWF ..| | .| EDFKCHPFF |
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Kinase | NDR1_b.AA | Akt | 131-276 | 44 | 9.2e-64 | 202.68 | In-house | 1-149 (264) | Show / Hide |
Range on Protein: 131-276 Range on HMM: 1-149/264 Sequence Identity: 44% (66 aa) FELLTIIGRGAFGEVRLCREKRSGQVY-AMKKLQKSEMLRRGQ-ASATAERNLLAEVDSNCIVKLFCSFQDDEYLYLIMEYLPGGDMMTLLMRKDTLTED |..| ..|.|.|| | |...| ....| ||| |.|. . ..| . . .|||.| .... ||.| |||. ..||..|.| .||. ..| || . .|| FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED EARFYVGQAILAIESIHRHNYIHRD-IKPDNLLLDKNGHMKLSDFGLCK .||||. . ||||| | .| | || || |.|.||.|| .| |||||| RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCK |
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Kinase | NDR1_b.AA | GEK | 131-275 | 53 | 5e-62 | 206.89 | In-house | 1-147 (269) | Show / Hide |
Range on Protein: 131-275 Range on HMM: 1-147/269 Sequence Identity: 53% (78 aa) FELLTIIGRGAFGEVRLCREKRSGQVYAMKKLQKSEMLRRGQASA-TAERNLLAEVDSNCIVKLFCSFQDDEYLYLIMEYLPGGDMMTLLMR-KDTLTED ||.| .||||||||| . | ..|||||| |.| |||.|. .. || | . |. | .| |||..||||.|.| |||..||| . .| | || FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED EARFYVGQAILAIESIHRHNYIHRDIKPDNLLLDKNGHMKLSDFGLC ||||.. ..||.|.|. .|.||||||||.|||.|||..| ||| | MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGSC |
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Kinase | NDR1_b.AA | ROCK | 131-275 | 52 | 9.1e-59 | 198.71 | In-house | 1-145 (263) | Show / Hide |
Range on Protein: 131-275 Range on HMM: 1-145/263 Sequence Identity: 52% (76 aa) FELLTIIGRGAFGEVRLCREKRSGQVYAMKKLQKSEMLRRGQ-ASATAERNLLAEVDSNCIVKLFCSFQDDEYLYLIMEYLPGGDMMTLLMRKDTLTEDE |... .|||||||||.| |.|.| .||||| | | ||..| | ||...| |. ||.|.. |||| |||..|.|.||||.. || . . | FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVN-LMSNYDVPEKW ARFYVGQAILAIESIHRHNYIHRDIKPDNLLLDKNGHMKLSDFGLC |||| .||...|| .||||.||||.|||| ||.|| ||| | ARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTC |
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Kinase | NDR1_b.AA | Pkinase | 131-276 | 31 | 1.2e-50 | 179.38 | Pfam | 1-160 (293) | Show / Hide |
Range on Protein: 131-276 Range on HMM: 1-160/293 Sequence Identity: 31% (51 aa) FELLTIIGRGAFGEVRLCREKRSGQVYAMKKLQKSEMLRRGQASATA--ERNLLAEVDSNCIVKLFCSFQDDEYLYLIMEYLPGG----DMMTLLM--RK .... .||.|.||.|..|..| .|...|.|.. |.. . ... | ....... .||.|...|.|. ..|..|||..|| | ..... |. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH DTL--TEDEARFYVGQAILAIESIHRHNYIHRDIKPDNLLLDKNGHM----KLSDFGLCK .. .|.|..||. | . ..| .|... ||||.||.|.|.|.||| |..||||.| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAK |
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Kinase | NDR1_b.AA | MAST | 334-433 | 45 | 2.2e-44 | 133.1 | In-house | 229-337 (337) | Show / Hide |
Range on Protein: 334-433 Range on HMM: 229-337/337 Sequence Identity: 45% (50 aa) VGTPDYIAPEVLLKKG-YGMECDWWSLGAIMYEMLVGYPPFYSDEPMS-TCRKIVNWRMHLKFPEE------AKLSAEAKDFISRLI-CDVEHRLGTRGV .||||||||||.|..| || ||||.| |||| |||.||| |.| . .|.| .. .||| ..|.||.| |..| . |||..|. CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA HELKGHSWF .| | | | DEIKQHPFF |
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Kinase | NDR1_b.AA | MAST | 334-433 | 44 | 2.8e-40 | 127.32 | In-house | 225-334 (334) | Show / Hide |
Range on Protein: 334-433 Range on HMM: 225-334/334 Sequence Identity: 44% (49 aa) VGTPDYIAPEVLLKKG-YGMECDWWSLGAIMYEMLVGYPPFYSDEPMSTCRKIVNWRMH-LKFPEE------AKLSAEAKDFISRLI-CDVEHRLGTR-G .||||||||||.|..| .|. ||||.| |||| |||.||| |.| . .|.| . ..||. ..| ||.| |..| .| . |||.. | CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG VHELKGHSWF ..| | | | ADEVKQHPFF |
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Kinase | NDR1_b.AA | GEK | 334-433 | 50 | 9e-40 | 130.92 | In-house | 162-269 (269) | Show / Hide |
Range on Protein: 334-433 Range on HMM: 162-269/269 Sequence Identity: 50% (55 aa) VGTPDYIAPEVL--LKKG---YGMECDWWSLGAIMYEMLVGYPPFYSDEPMSTCRKIVNWRMHLKFPEEAK---LSAEAKDFISRLICDVEHRLGTRGVH |||||||.||.| . | || |||||||| .||||| | |||.. . | ||.|.. |..||.. . .|.||||.| .||| ||||| |.. VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQ ELKGHSWF . | | .| DFKKHPFF |
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Kinase | NDR1_b.AA | ROCK | 334-433 | 50 | 9.4e-39 | 129.44 | In-house | 160-263 (263) | Show / Hide |
Range on Protein: 334-433 Range on HMM: 160-263/263 Sequence Identity: 50% (53 aa) VGTPDYIAPEVLLKKG----YGMECDWWSLGAIMYEMLVGYPPFYSDEPMSTCRKIVNWRMHLKFPEEAKLSAEAKDFISRLICDVEHRLGTRGVHELKG |||||||.|||| .| || |||||| | .|||||| ||| | ..| ||.. . ||||.....| .||| | . . | |.||| || ..| VGTPDYISPEVLKSQGQDGEYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLKFPDDVEISKQAKDLICKFLTDREQRLGRNGVDDIKQ HSWF | .| HKFF |
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Kinase | NDR1_b.AA | Akt | 330-433 | 41 | 4.8e-36 | 112.65 | In-house | 159-264 (264) | Show / Hide |
Range on Protein: 330-433 Range on HMM: 159-264/264 Sequence Identity: 41% (45 aa) AYSTVGTPDYIAPEVLLKKGYGMECDWWS-LGAIMYEMLVGYPPFYSDEPMSTCRKIVNWRMHLKFPEEAKLSAEAKDFISRLIC-DVEHRLG--TRGVH ... ||| |.|||.|...|... .|||. ||..||||. | ||||.. || | .|||. ..| |.||.||.| | ..||| ... TKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKN--QPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQ ELKGHSWF |.| | || EIKRHPWF |
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Kinase | NDR1_b.AA | Pkinase | 334-433 | 31 | 4.7e-24 | 86.14 | Pfam | 172-293 (293) | Show / Hide |
Range on Protein: 334-433 Range on HMM: 172-293/293 Sequence Identity: 31% (39 aa) VGTPDYIAPEVLL-KKGYGMECDWWSLGAIMYEMLVGYPPFYSD------EPMSTCRKIVNWRMHLKFPEEAKLS-----------------AEAKDFIS .|||.|.||||.. ..|| ..|.||.| |.|||| |.|||... ..| ..| . | .|.. | |.||||. CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK RLIC-DVEHRLGTRGVHELKGHSWF ...| | . |.. .... | || WCLCKDPKKRPT---AEQILQHPWF |
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Kinase | NDR1_b.AA | Pkinase_Tyr | 131-276 | 27 | 2e-11 | 39.32 | Pfam | 1-159 (270) | Show / Hide |
Range on Protein: 131-276 Range on HMM: 1-159/270 Sequence Identity: 27% (45 aa) FELLTIIGRGAFGEVRLCREK-----RSGQVYAMKKLQKSEMLRRG--QASATAERNLLAEV-DSNCIVKL--FCSFQDDE-YLYLIMEYLPGGDMMTLL ... .|.||||||.... | .| | |.| | . ... .| ... . . ||.| |. |.. ..|..||| |.||. . | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPV-AVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL MR----KDTLTEDEARFYVGQAILAIESIHRHNYIHRDIKPDNLLLDKNGHMKLSDFGLCK . |. || . . | . | ...|.||||. | |...|...| .||||.. RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR |
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Kinase | NDR1_b.AA | TyrKc | 131-419 | 18 | 2.3e-11 | -38.94 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 131-419 Range on HMM: 1-280/280 Sequence Identity: 18% (59 aa) FELLTIIGRGAFGEVRLCREKRSGQVYAMKKLQKSEMLRRGQASATAERNLLAEV--DSNCIVKLFCSFQDD-------EYLYLIMEYLPGGDMMTLL-M .|. ..|.||||||.... | . | |.|... .. | ... .. . .||.|. .. | |...||| |.|| | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK RKDTLTEDEARFYVGQAILAIESIHRHNYIHRDIKPDNLLLDKNGHMKLSDFGLCKPLDCS-NLPALYENEPGIEEKIKDALTFEALK--SPARRRTQQE ....|. .. . |. | .|..|.||||. | |...|...| |||||.. .. . ... ... . . | | | HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--------ESKDYYRKKEHKGGKTMLPIR------ QLLHWQRNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEML-VGYPPFYS-----DEPMSTCRKIVNWRMHLKFPE---------EAKLSA |||.. .. . . | || | |.|.. | .| . .. ... . .. . |. ... ---------------------WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ EAKDFISR--------LICDVEHRL |. . . ... IMKQCWHEDPEDRPTFSEI--HECF |
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Kinase | NDR1_b.AA | Pkinase_C | 451-500 | 31 | 5e-11 | 42.09 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 451-500 Range on HMM: 1-46/46 Sequence Identity: 31% (16 aa) EVANELDTQNFE-KFEDSNSQAQPASKSGPWRKMLPSRDVNFVGYTYKNFE .| ...||.||. |.| . | .|| | .. . .|.|.||.|.. QVKSPTDTSNFDPEFTDEPPMDTP----PDWR-MSSGDQEPFRGFTYVNPD |
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Kinase | NDR1_b.AA | S_TK_X | 434-498 | 25 | 1.1e-10 | 42.8 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 434-498 Range on HMM: 1-79/79 Sequence Identity: 25% (21 aa) KGVDWNKLY----DMEAAFKPEVA----NELDTQNFE-KFED---SNSQAQPASKSGPWRKMLPSRDVN----FVGYTYKN .|.||.||| .|. |||.. .. || ||. .|.. . . ..|.. .. | .. ... | |.||.. RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNE-METE-IPPDPFRGFTYVF |