Gene NDR1_a-1 (S.moellendorffii)
NDR1_a-1
Species: S.moellendorffii
Alias: NDR1_a-1
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
NDR1_a-1.AA | Protein | None | 527 | None | Fasta, JSON |
NDR1_a-1.NA | RNA | None | 1584 | None | Fasta, JSON |
NDR1_a-1.kin_dom | Protein Kinase Domain | None | 305 | None | Fasta, JSON |
Protein domains of NDR1_a-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
Kinase | NDR1_a-1.AA | NDR | 124-428 | 50 | 5.70000000001e-193 | 601.26 | In-house | 1-350 (350) | Show / Hide |
Range on Protein: 124-428 Range on HMM: 1-350/350 Sequence Identity: 50% (175 aa) FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVD--SNYIVKLYCSFQDDEYLYLIMEYLPGGDMMT---LLMRKDT || ..|||.||||||.|.|.|.|| .||||...||||... || ||.||| .||.| ....||||.||||. ||||.|||.||||||| |||..|. FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI LTENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLCKP------LDCSN----------FPMLRENDLSTDKNQRDGLDVNRR-T .||..|.||||| |.||||.|| ||||||||||.|.|| ||.||.|||||. . . | . ......... | .. . FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN SSPAPRRT---QQEQLQH-----------WQRNRRMLAYSTVGTPDYIAPEVLLK-KGYGMECDWWSLGAILYEMLVGFPPFYSDEPMFTCRKIVNWRTH |.| .. . |.. | |..||| |||||||||||.||||... .||...|||||||.|.||||||.|||.||.| ||.|| ||.. SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT L-----KFPDEAKLSVEARDLMSRLLC-GVDQRLGT--KGTHEIKSHSWF . || ||.||.|| || ||.| |.||| || .|||||..| WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF |
|||||||||
Kinase | NDR1_a-1.AA | AGC | 124-428 | 31 | 8.3e-179 | 467.11 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 124-428 Range on HMM: 1-395/395 Sequence Identity: 31% (135 aa) FELLTIIGRGAFGEVRLCREK------STGYVYAMKKLKKSE---MLRRGQVEHVKAE------------RNLLAEVD----------SNYIVK-LYCSF ||.|..||.|.||.|.|.|.| .|| .||||.|||.. .... .|||...| || |.... . .||| |..|| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QDDEY--LYLIMEYLP---------GG-DMMTLLM---RKDTLTENEAKFYIAE-------AVLAIESIHK-HKYIHRD-IKPDNLLLDKNGHLKLSDFG ||... ||..|||.| || .... |. .. ...|..|.||.|| |||.|..|. ...|||| .||.|.|||..||.||.||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LCKPLDC------------------SNFPMLRENDLSTDKNQRDGLDVNRRTSSPAPRRTQQEQLQHWQRNR-----------RMLAYSTVG--TPDYIA ||| . ... . ... . | . . ...||||. | .... .| ||.|.| LCKEGMNDGEKGQQSQSNMKFHWHNKKY-Q-KS-NMD-T-N-------------------K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMA PEVLLKKGYGMECDWWS--LGAILYEMLVGFPPFYSDE----------PMFTCRKIV------NWRTHLKFP------DEAKLSVEARDLMSRLLC-GVD ||.| || .||||| ||...||||.| ||||.|. || . || ||. .. || .. ..|.||.||...||| . PEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPE QRLGTK-------GTHEIKSHSWF .|||.. |. |||.| || KRLGCGGNDFGDKGAEEIKNHPWF |
|||||||||
Kinase | NDR1_a-1.AA | MAST | 124-428 | 35 | 7.6e-123 | 377.33 | In-house | 1-337 (337) | Show / Hide |
Range on Protein: 124-428 Range on HMM: 1-337/337 Sequence Identity: 35% (121 aa) FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQD--DEYLYLIMEYLPGGDMMTLLMRKD-TLT || . .|..||.| | | . |.|. .|||..... .... ||..|..||| |.... ...||...||| ..||...|||. ||| .|| .. FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP ENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLCKP--LDCSNFPMLRENDLSTD-----KNQRDGLDVNRRTSSPAPRRT---- |..||.|||| ||..| .|.. .|||.||||.|.|.|||.|| |||| | .| .. .. | .|. .. . . | .... .. . EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTT--NHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTN -----------QQEQLQHWQRNRRMLAYSTVGTPDYIAPEVLLKKG-YGMECDWWSLGAILYEMLVGFPPFYSDEPMF-TCRKIVNWRTHLKFPDE---- |..| . . . .||||||||||.|..| || ||||.| |.|| ||| ||| |.| . .|.| .. .|.| KNQIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPN --AKLSVEARDLMSRLLCGVD--QRLGTKGTHEIKSHSWF ..| ||.||...|| .. .|||..| .|||.| | DDDCMSPEAQDLIKKLLQ-PNPKKRLGANGADEIKQHPFF |
|||||||||
Kinase | NDR1_a-1.AA | MAST | 124-428 | 36 | 6e-118 | 381.9 | In-house | 1-334 (334) | Show / Hide |
Range on Protein: 124-428 Range on HMM: 1-334/334 Sequence Identity: 36% (124 aa) FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRKDTLTENE || .|..||.| | | . |.|. .|||..|||.|... .|..|..||| ||.......||...||| ..||...|||. ||| .|| .. |. FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM AKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLCKP--LDCSNFPMLRENDLSTDKNQRDGLDVNRRTSSPAPRRTQQEQLQH----- ||.|||| ||..| .|.| .|||.||||.|.|.||| || |||| | | .| |. |. ... .| |..... .. .|.. AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLN--MMYEGYTPPNI-------FNNSTDPMNKNQQDYSQFPGDFGIN ---------------------WQRNRRMLAYSTVGTPDYIAPEVLLKKG-YGMECDWWSLGAILYEMLVGFPPFYSDEPMFTCRKIVNWR---THLKFP- . . . .||||||||||.|..| .|. ||||.| |.|| ||| ||| |.| . .|.| . . . .. GNTNKNQIQQQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGG ---DEAKLSVEARDLMSRLLCG-VDQRLGTK-GTHEIKSHSWF |. ..|.||.||...|| .|||.. | .|.|.| | DINDDEAMSPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF |
|||||||||
Kinase | NDR1_a-1.AA | AktR | 124-428 | 36 | 5.2e-106 | 358.48 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 124-428 Range on HMM: 1-268/268 Sequence Identity: 36% (116 aa) FELLTIIGRGAFGEVRLCREK-STGYVYAMKKLKKSEMLRRGQVEHVKAERNLLA-EVDSNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRKDTLTE |... ..|.||||.| |...| .. .|||| .||... .| | .|. ||| .. ... . ||||. .||..|.|..|||| |||.. . | .| ...| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE NEAKFYIAEAVLAIESIHKH-KYIHRDIKPDNLLLDKNGHLKLSDFGLCKPLDCSNFPMLRENDLSTDKNQRDGLDVNRRTSSPAPRRTQQEQLQHWQRN ..|.||.|. .||.| |.| . | ||.||.|.|||..||.|..|||| | || .. EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-------------------------------------------LQ-FMMH RRMLAYSTVGTPDYIAPEVLLK-KGYGMECDWWSLGAILYEMLVGFPPFYS--DEPMFTCRKIVNWRTHLKFPDEAKLSVEARDLMS-RLLCGVDQ-RLG .. .||| .||| |.|||...| ||.. .|||..|. .|||..| ||||. .. || || . . .|||. ...| ...|| .||| . ||| YDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMF--QKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLG --TKGTHEIKSHSWF ..|. ||||| || YYCNGWEEIKSHPWF |
|||||||||
Kinase | NDR1_a-1.AA | DMPK | 124-269 | 53 | 5.3e-106 | 262.86 | In-house | 1-147 (270) | Show / Hide |
Range on Protein: 124-269 Range on HMM: 1-147/270 Sequence Identity: 53% (78 aa) FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRKD-TLTEN || |..||||.|||| . |.|.|. |||||...| ||| | .. .. ||. .. .| |..|.. |||..|||..||| ||||. ||. | . . |. FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED EAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLC |.||.|| |||| |||. |.|||||||| |||..||.|| ||| | MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSC |
|||||||||
Kinase | NDR1_a-1.AA | S_TKc | 124-428 | 32 | 7e-103 | 349.02 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 124-428 Range on HMM: 1-231/231 Sequence Identity: 32% (103 aa) FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPG--GDMMTLLMRKDT--- .|.| .||.||||.|..||.|.|| ..|.|..| ||.. |...| . . .||||| .||| ..||..|||..| ||..... .. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LTENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLCKPLDCSNFPMLRENDLSTDKNQRDGLDVNRRTSSPAPRRTQQEQLQ ..| .|.||... ..|.| .|.|. ||||.||.|.|||. |.|..||||.. | RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------------------- HWQRNRRMLAYSTVGTPDYIAPEVLLKKGYGM-ECDWWSLGAILYEMLVGFPPFYSDEPMFTCRKIVNWRTHLKFPDEAKLSVEARDLMSRLLC-GVDQR .. .|||.|.||||| ||| .|||||.| ||||||.| |||. ... . .||. | ||.|.....|. ..| ----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKR LGTKGTHE----IKSHSWF .. . ||.| || PTA-EALQDEWDIKCHPWF |
|||||||||
Kinase | NDR1_a-1.AA | RSK | 124-428 | 33 | 1.1e-100 | 340.81 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 124-428 Range on HMM: 1-278/278 Sequence Identity: 33% (108 aa) FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQ-VEHVKAERNLLAEVD-SNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRKDT--- ..|. .| |.. .| |. . || .|||| |||... .| ..|...||| |... . ||.|. .||....|||||||..||.. | | .. . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LTENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDK---NGHLKLSDFGLCKPLDCSNFPMLRENDLSTDKNQRDGLDVNRRTSSPAPRRTQQEQLQ ..|.||.||.|| |||.| .|... ||||.||.| |.| .||.||.|||.|| . FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF------------------------------------------- HWQRNR-RMLAYSTVGTPDYIAPEVLL----KKGYGMECDWWSLGAILYEMLVGFPPFYS---DEPMFTCRKIVNWRTHLKFPDEAKLSVEARDLMSRLL |.. .... ..| .|.|||.| ..|.. |||||||...||||.|.|||.. . . . ..| . . |..| ..|| ||.|| ...| ---RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKML C-GVDQRLG--TKGTHEIKSHSWF . .||| ... |||.|.|| HRDPHKRLGCGPQDAEEIKQHPWF |
|||||||||
Kinase | NDR1_a-1.AA | Akt | 124-270 | 46 | 9.8e-74 | 235.06 | In-house | 1-149 (264) | Show / Hide |
Range on Protein: 124-270 Range on HMM: 1-149/264 Sequence Identity: 46% (70 aa) FELLTIIGRGAFGEVRLCREKSTGYVY-AMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRKDTLTEN |..| ..|.|.|| | |...|.|. .| ||| |||. . ..||||.|.|||.| .....||.|. |||. ..||..|.| .||. ..| || . .|. FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED EAKFYIAEAVLAIESIHKHKYIHRD-IKPDNLLLDKNGHLKLSDFGLCK .|.||.|| .|||| |.. | || || |.|.||.||..| |||||| RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCK |
|||||||||
Kinase | NDR1_a-1.AA | GEK | 124-269 | 54 | 3.9e-65 | 217.49 | In-house | 1-147 (269) | Show / Hide |
Range on Protein: 124-269 Range on HMM: 1-147/269 Sequence Identity: 54% (80 aa) FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMR-KDTLTEN ||.| .||||||||| . |.|. ||||| |.| |||.|. . . || | . |. .| .| |||..||||.|.| |||..||| . .| | |. FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED EAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLC |.||||| |.||.|.|. .|.||||||||.|||.|||..| ||| | MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGSC |
|||||||||
Kinase | NDR1_a-1.AA | ROCK | 124-269 | 52 | 4.2e-62 | 210.25 | In-house | 1-145 (263) | Show / Hide |
Range on Protein: 124-269 Range on HMM: 1-145/263 Sequence Identity: 52% (77 aa) FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRKDTLTENE |... .|||||||||.| |.||. ||||| | | ||..| ||...| |..||.|.. |||| |||..|.|.||||.. || . . | FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVN-LMSNYDVPEKW AKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLC |.|| .| |||...|| .||||.||||.|||| ||||| ||| | ARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTC |
|||||||||
Kinase | NDR1_a-1.AA | DMPK | 329-428 | 49 | 4.6e-62 | 151.74 | In-house | 162-270 (270) | Show / Hide |
Range on Protein: 329-428 Range on HMM: 162-270/270 Sequence Identity: 49% (54 aa) VGTPDYIAPEVL--LKKG----YGMECDWWSLGAILYEMLVGFPPFYSDEPMFTCRKIVNW-RTHLKFPDEAK--LSVEARDLMSRLLCGVDQRLGTKGT |||||||.|||| . . || ||||||.| ..||||.| ||| | | ||.| ..||.|||. | .|.||.|| .||| ..||| | VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGY HEIKSHSWF ..| | .| EDFKCHPFF |
|||||||||
Kinase | NDR1_a-1.AA | Pkinase | 124-270 | 34 | 7.6e-53 | 186.67 | Pfam | 1-160 (293) | Show / Hide |
Range on Protein: 124-270 Range on HMM: 1-160/293 Sequence Identity: 34% (55 aa) FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVK-AERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPGG----DMMTLLM--RK .... .||.|.||.|..|..|.|| ..|.|..||.. ...|.. .| ....... .||.||..|.|. ..|..|||..|| | ..... |. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH DTL--TENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHL----KLSDFGLCK .. .|.|.|||. . . ..| .|... ||||.||.|.|.|.|||. |..||||.| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAK |
|||||||||
Kinase | NDR1_a-1.AA | ROCK | 329-428 | 50 | 1.2e-37 | 125.56 | In-house | 160-263 (263) | Show / Hide |
Range on Protein: 329-428 Range on HMM: 160-263/263 Sequence Identity: 50% (53 aa) VGTPDYIAPEVLLKKG----YGMECDWWSLGAILYEMLVGFPPFYSDEPMFTCRKIVNWRTHLKFPDEAKLSVEARDLMSRLLCGVDQRLGTKGTHEIKS |||||||.|||| .| || |||||| | .|||||| ||| | . | ||.. .. |||||....| .|.||. . | .|||| .| .|| VGTPDYISPEVLKSQGQDGEYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLKFPDDVEISKQAKDLICKFLTDREQRLGRNGVDDIKQ HSWF | .| HKFF |
|||||||||
Kinase | NDR1_a-1.AA | Akt | 325-428 | 41 | 8.1e-37 | 115.17 | In-house | 159-264 (264) | Show / Hide |
Range on Protein: 325-428 Range on HMM: 159-264/264 Sequence Identity: 41% (45 aa) AYSTVGTPDYIAPEVLLKKGYGMECDWWS-LGAILYEMLVGFPPFYSDEPMFTCRKIVNWRTHLKFPDEAKLSVEARDLMSRLLCGV-DQRLG--TKGTH ... ||| |.|||.|...|... .|||. ||...|||. |.||||.. || | .|||| ..| |..|| |.|| ..||| .... TKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKN--QPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQ EIKSHSWF |||.| || EIKRHPWF |
|||||||||
Kinase | NDR1_a-1.AA | GEK | 329-428 | 46 | 1.6e-36 | 119.86 | In-house | 162-269 (269) | Show / Hide |
Range on Protein: 329-428 Range on HMM: 162-269/269 Sequence Identity: 46% (50 aa) VGTPDYIAPEVL--LKKG---YGMECDWWSLGAILYEMLVGFPPFYSDEPMFTCRKIVNWRTHLKFPDEAK---LSVEARDLMSRLLCGVDQRLGTKGTH |||||||.||.| . | || |||||||| ..|||| | |||.. . | ||.|.. |..||.. . .| ||.||. .|.| ..||| | . VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQ EIKSHSWF . | | .| DFKKHPFF |
|||||||||
Kinase | NDR1_a-1.AA | Pkinase | 329-428 | 30 | 1.5e-23 | 84.37 | Pfam | 172-293 (293) | Show / Hide |
Range on Protein: 329-428 Range on HMM: 172-293/293 Sequence Identity: 30% (38 aa) VGTPDYIAPEVLL-KKGYGMECDWWSLGAILYEMLVGFPPFYSD------EPMFTCRKIVNWRTHLKFPDEAKLS-----------------VEARDLMS .|||.|.||||.. ..|| ..|.||.| |||||| | |||... ..|. ..| ..| .| . | |..|... CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK RLLC-GVDQRLGTKGTHEIKSHSWF ..|| .|.. ..|. | || WCLCKDPKKRPT---AEQILQHPWF |
|||||||||
Kinase | NDR1_a-1.AA | Pkinase_Tyr | 124-270 | 28 | 2.3e-13 | 45.86 | Pfam | 1-159 (270) | Show / Hide |
Range on Protein: 124-270 Range on HMM: 1-159/270 Sequence Identity: 28% (45 aa) FELLTIIGRGAFGEVRLCREK----STGYVYAMKKLKKSEMLR-RGQVEHVKAERNLLAEV-DSNYIVKLYCSFQ-DDEY--LYLIMEYLPGGDMMTLLM ... .|.||||||.... | .|.. | |.|| . | . | .| ... . . ||.|| ..| .|..||| |.||. . | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR R----KDTLTENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLCK . |. || . . .. . | . ...||||. | |...|.. | .||||.. KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR |
|||||||||
Kinase | NDR1_a-1.AA | TyrKc | 124-358 | 19 | 3.5e-12 | -25.68 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 124-358 Range on HMM: 1-280/280 Sequence Identity: 19% (56 aa) FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEV--DSNYIVKLYCSFQDD-------EYLYLIMEYLPGGDMMTLL- .|. ..|.||||||.... | . | |.||.. .| | ... .. . ||.|| .. | |...||| |.|| | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR MRKDTLTENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLCKPLDCS-NFPMLRENDLSTDKNQRDGLD-------------VNR ....|. . . . | .|....||||. | |...|.. | |||||.. .. . |.. .| ...| . . KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG---ESKDYYRKKEHKGGKTMLPIRWMAPECINYG --------------------RTSSPAPR-----RTQQEQLQHWQRNRRMLAYST------VGTPDYIAPEVLLK---KGYGMECDWWSLGAIL . .| | . || ... .. .|| |. || . . .. . . . . .. KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF |
|||||||||
Kinase | NDR1_a-1.AA | Pkinase_C | 446-495 | 26 | 1.5e-11 | 43.93 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 446-495 Range on HMM: 1-46/46 Sequence Identity: 26% (13 aa) EVNNELDTQNFEKFEEAIGQTQSSSKAGPWRKMLPSKDVNFVGYTYKNFE .|....||.||..... . .. .|| | .... .|.|.||.|.. QVKSPTDTSNFDPEFTDEPPMDTP---PDWR-MSSGDQEPFRGFTYVNPD |
|||||||||
Kinase | NDR1_a-1.AA | S_TK_X | 429-493 | 24 | 4.2e-09 | 37.49 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 429-493 Range on HMM: 1-79/79 Sequence Identity: 24% (22 aa) KGVEWDKLY----EMEAAFKPEVN----NELDTQNFE-KFEEAIGQTQSSSKAGPWRKMLPSK------DVN----------FVGYTYKN .|. ||||| |.|. |||... .. || ||. .|.|. . ... . | | |.||.. RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-----------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |