MAST_c-2

Species: S.moellendorffii
Alias: MAST_c-2
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
MAST_c-2.AA Protein None 983 None Fasta, JSON
MAST_c-2.NA RNA None 2952 None Fasta, JSON
MAST_c-2.kin_dom Protein Kinase Domain None 287 None Fasta, JSON

Protein domain

Protein domains of MAST_c-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MAST_c-2.AA AGC 576-862 32 1.5e-174 455.86 In-house 1-395 (395) Show / Hide
Range on Protein: 576-862
Range on HMM: 1-395/395
Sequence Identity: 32% (134 aa)

FEIIKPISRGAFGRVFLARKR------TTGDLFAIKVLRKAD---MIRKNAVESVHAE------------RNILIHAK----------NPFLVR-FFYSF
||..|.|..|.||.|.|.||.      .||...|.|||.|..   ...|| || ...|            |||| ...          .||.|.  .|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

TCKEN--LYLVMEYLN--------GGDMYSMLRNLG-----CLDEDMARYYIAE-------LVLALEYLHS-LAVIHRD-LKPDNILIAHDGHIRLTDFG
  |..  ||.||||..        ||.. ..|.. |     ..||..||.|.||       .||||||||| . .|||| |||.|||. .||||.|||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKVGLI----------------------------NSTDDLSAPASRGAAVAVEKHDSSDSSTKKG-------------RQQKTVG--TPDYLAPEILLG
|.|.|                              |                  |     .  ...             | .  .|  ||.|.|||||  
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTN------------------K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL--

TAHGYPADWWS--VGVILFEFLTGIPPFNAEDPQ----------MIFENILNR------NIPWP-----NIPG--DMSFEAADFIDKLLAEDPNHRLGAK
  .|...||||  .|....|.|||.|||....||           .|..|.|.      ....|     ..|.   .| || |.| |||  ||..|||..
--YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCG

-------GAAEVKAHPFF
       || |.|.||.|
GNDFGDKGAEEIKNHPWF

Kinase MAST_c-2.AA MAST 576-862 43 1.8e-171 528.67 In-house 1-337 (337) Show / Hide
Range on Protein: 576-862
Range on HMM: 1-337/337
Sequence Identity: 43% (147 aa)

FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAKNPFLVRFFYSFTC--KENLYLVMEYLNGGDMYSMLRNLG-CLD
||.||.||.||.|.|.|.....|.|.||.||... |.|.|| |..| .|||||  ..||| | .||||    |. |..||||..|||  | ||..| |..
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLIN-----------------STDDLSAPASRGAAV----AVEKHDSSD
|.||. ||||.||.|||||| . .||||||||.||  .||| ||||||||||...                  .....              ...  . .
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN

SSTK-----------------KGRQQKTVGTPDYLAPEILLGTA-HGYPADWWSVGVILFEFLTGIPPFNAEDPQ-MIFENILN--RNIPWPNI-----P
.. .                 . .... .|||||.|||..||.  .| |.||||.|.|..|||.|.||||.. |. |||.||.|  |.| || .      
QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDD

GDMSFEAADFIDKLLAEDPNHRLGAKGAAEVKAHPFF
  || || | |.|||. .|  ||||.||.|.| ||||
DCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF

Kinase MAST_c-2.AA MAST 576-862 45 3.3e-163 530.26 In-house 1-334 (334) Show / Hide
Range on Protein: 576-862
Range on HMM: 1-334/334
Sequence Identity: 45% (153 aa)

FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAKNPFLVRFFYSFTCKENLYLVMEYLNGGDMYSMLRNLGCLDEDM
||.|||||.||.|.|.|.....|.|.||.||..|.|||.|| |..| .|||||  ..||| | .||||  |..|..||||..|||  | |...|..||.|
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLINSTDDLSAPASRGAAVAVEKHDSSDSSTKKGR-----------------
|. ||||.||.|||||| . .||||||||.||  .||| ||||||||||... .  .         .  .. . ... ..  .                 
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

--------------------QQKTVGTPDYLAPEILLGTA-HGYPADWWSVGVILFEFLTGIPPFNAEDPQMIFENILNRN---IPWPNI-----PGDMS
                    ... .|||||.|||..||.  || | ||||.|.|..|||.|.|||| ..|..||.||||||   | ||          ||
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

FEAADFIDKLLAEDPNHRLGAK-GAAEVKAHPFF
 || | |.|||. ||. ||||. ||.||| ||||
PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF

Kinase MAST_c-2.AA NDR 576-862 38 3.3e-145 451.2 In-house 1-350 (350) Show / Hide
Range on Protein: 576-862
Range on HMM: 1-350/350
Sequence Identity: 38% (133 aa)

FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAK--NPFLVRFFYSFTCKENLYLVMEYLNGGDMYS---MLRNLGC
|||||.|..||||.|.|.||. ||...|.|..||..|..|| | .| ||| |.  |.  ||. |. .|||  | .|||||||. |||| .   .| ....
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLI----------------------------NSTDDLSAPASRGAAV
..||.|| ||||.|.|.|..|..  ||||.||||.||  |||| ||||||.. |.|                             . ....   ..... 
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN

AVEKHDSSDSST----------------KKGRQQ-----KTVGTPDYLAPEILLG-TAHGYPADWWSVGVILFEFLTGIPPFNAEDPQMIFENILNRNIP
.  . ... ..|                .. ...     .|||||||.|||.... | ..   ||||.|.|..|.|.|.|||....|| ....|.|  . 
SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT

WP----NIP--GDMSFEAADFIDKLLAEDPNHRLGA--KGAAEVKAHPFF
|.    ..|    .| ||.| | .|.. ||.||||.  ||. |.|.||||
WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF

Kinase MAST_c-2.AA AktR 576-862 33 6.9e-110 371.38 In-house 1-268 (268) Show / Hide
Range on Protein: 576-862
Range on HMM: 1-268/268
Sequence Identity: 33% (101 aa)

FEIIKPISRGAFGRVFLARKR-TTGDLFAIKVLRKADMIRKNAVESVHAERNILI-HAKNPFLVRFFYSFTCKENLYLVMEYLNGGDMYSMLRNLGCLDE
|...|.. .||||.|.|..|. ......|.|...| ..|..|. . .  ||||.. ....||.|...|.|  ||.|...|||  ||.....|.. . ..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DMARYYIAELVLALEYLHSL-AVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLINSTDDLSAPASRGAAVAVEKHDSSDSSTKKGR-----QQKTVGTPD
..|| |.|. .|||||||.   .| |||||.|||.  |||...|||||||                                 . .     ... .||| 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-------------------------------LQFMMHYDEKAYSFCGTPE

YLAPEILLG-TAHGYPADWWSVGVILFEFLTGIPPFNAEDPQMIFENILNRNIPWPNIPGDMSFEAADFID-KLLAEDPNHRLG--AKGAAEVKAHPFF
|.|||...    |....|||..|. ..| .||.|||.... . .|..|.. ..  ...| . |... |.|  |||  .||.|||  ..|. |.| ||.|
YMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase MAST_c-2.AA S_TKc 576-862 33 1.4e-106 361.27 SMART 1-231 (231) Show / Hide
Range on Protein: 576-862
Range on HMM: 1-231/231
Sequence Identity: 33% (100 aa)

FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAKNPFLVRFFYSFTCKENLYLVMEYLNG--GDMYSMLRNLGC---
.||...| .||||.|...|.. || ..|||...          |..  |..|| . . |..|.....|   ..||.||||..|  ||....... |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLINSTDDLSAPASRGAAVAVEKHDSSDSSTKKGRQQKTVGTPD
   ..| .||.|......||||.||. .|||||||.|||. .  || ..||||...                                       .|||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------------------------------TTFCGTPW

YLAPEILLGTAHGY-PADWWSVGVILFEFLTGIPPFNAEDPQMIFENILNRNIPWPNIPGDMSFEAADFIDKLLAEDPNHRLGAKGAAE----VKAHPFF
|.|||.|    .|. ..||||.|.||.|.|.| |||   ..||.|..|.             | || |||.|.|  ||..|..|  | .    .|.||.|
YMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF





Kinase MAST_c-2.AA RSK 579-862 34 5.8e-99 335.07 In-house 1-278 (278) Show / Hide
Range on Protein: 579-862
Range on HMM: 1-278/278
Sequence Identity: 34% (107 aa)

IKPISRGAFGRVFLARKR---TTGDLFAIKVLRKADMIRKNA-VESVHAERNILIHAK-NPFLVRFFYSFTCKENLYLVMEYLNGGDMYSMLRNLGC---
.|   .|..| ||| ||     || ..| |||.|| .....  .. . .||||| . .  ||.|. .|.|  .. |||.|||..||...  |.. ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAH---DGHIRLTDFGLSKVGLINSTDDLSAPASRGAAVAVEKHDSSDSSTKKGRQQKTVGTPD
..|| |..|.||.|||.|.||.. .|||||||.||| ..   .|||.|||||..| .                           .  .... .. ..| .
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF---------------------------RCDHNQWTMTFCYTIE

YLAPEILL----GTAHGYPADWWSVGVILFEFLTGIPPFNA---EDPQMIFENILNRNIPWPNIP--GDMSFEAADFIDKLLAEDPNHRLG--AKGAAEV
|.|||.|     . .|.  .|||| ||...| ||| ||| .   .... |...|.. ..  ...|    .| || |.| |.|  ||. |||   ..|.|.
YMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFS-LTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEI

KAHPFF
|.||.|
KQHPWF

Kinase MAST_c-2.AA Pkinase 576-862 27 7.5e-85 293.0 Pfam 1-293 (293) Show / Hide
Range on Protein: 576-862
Range on HMM: 1-293/293
Sequence Identity: 27% (90 aa)

FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVH-AERNILIHAKNPFLVRFFYSFTCKENLYLVMEYLNGG----DMYSMLR--NL
..|...| .|.||.|...... ||...|.|...| .   .  .. .. .|  |. . . |. ||....|. | ..|.||||..||    | .....  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GCL--DEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHI----RLTDFGLSKVGLINSTDDLSAPASRGAAVAVEKHDSSDSSTKKGRQQKT
||.  .|. .. |. ... .|||.||  .|||||||.|||| ..|||    ...||||.|.                               ...  .  
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---------------------------Y-NNS-MTTF

VGTPDYLAPEILL-GTAHGYPADWWSVGVILFEFLTGIPPFNAE------DPQMIFENILNRNIPWPNIPGD------------------MSFEAADFID
.|||.|.|||... |. .|...|.||.|.||.|.|.| |||  .      |.. ....|. . ....    .                  .| |. |||.
CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

KLLAEDPNHRLGAKGAAEVKAHPFF
..|. ||. |..   |.... ||.|
WCLCKDPKKRPT---AEQILQHPWF

Kinase MAST_c-2.AA MASTL 576-725 53 1.1e-74 254.42 In-house 1-151 (283) Show / Hide
Range on Protein: 576-725
Range on HMM: 1-151/283
Sequence Identity: 53% (81 aa)

FEIIKPISRGAFGRVFLA-RKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAKNPFLVRFFYSFTCKENLYLVMEYLNGGDMYSMLRNLGCLDED
| |.|||||||||.|.|  .    . |.|.||..||||| || .  | |||. |   | .| |  .||     ..||||||. |||. |.|   |  ||.
FVIVKPISRGAFGKVYLGYKNQKGKKLYAVKVMKKADMINKNMTHQVQAERDALALSKSQFCVHLYYSLQSASYVYLVMEYMIGGDVKSLLHMYGYFDEE

MARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGL
||..||.|.|.||.|||   .||||.||||.||  .|||.||||||||| .
MAIKYISEMVMALDYLHRHGIIHRDIKPDNMLISNEGHIKLTDFGLSKVTM

Kinase MAST_c-2.AA Akt 576-726 49 2.1e-74 237.23 In-house 1-153 (264) Show / Hide
Range on Protein: 576-726
Range on HMM: 1-153/264
Sequence Identity: 49% (75 aa)

FEIIKPISRGAFGRVFLARKRTTGDLF-AIKVLRKADMIRKNAVESVHAERNILIHAKNPFLVRFFYSFTCKENLYLVMEYLNGGDMYSMLRNLGCLDED
|...| . .|.||.|||..|  |.... |.|||.|   | || || . .||||| | ..||.|   |||  ...||.||.| |||. .. |.  .  .||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

MARYYIAELVLALEYLHSLAVIHRD-LKPDNILIAHDGHIRLTDFGLSKVGLI
 ||.|.||..||.|.|||  .| || ||| |||. .||||.||||||.| ..|
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENII

Kinase MAST_c-2.AA SGK 576-722 40 1.4e-72 223.34 In-house 1-173 (283) Show / Hide
Range on Protein: 576-722
Range on HMM: 1-173/283
Sequence Identity: 40% (70 aa)

FEIIKPISRGAFGRVFLARKRTT------------------GDLFAIKVLRKADMI-------RKNAVESVHAER-NILIHAKNPFLVRFFYSFTCKENL
|...| |  | ||.|.....  .                  ....|.|||.|.  |       .|. .  . ||| .||   | ||.|   |.|  |. |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLVMEYLNGGDMYSMLRNLGCLDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSK
|.||.|.|||.| . |.  ... || || | ||.|.|||||||. .|.|||||.|||  |.||..||||||.|
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCK

Kinase MAST_c-2.AA PKA 576-722 48 2.8e-65 223.16 In-house 1-149 (263) Show / Hide
Range on Protein: 576-722
Range on HMM: 1-149/263
Sequence Identity: 48% (73 aa)

FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHAKNPFLVR-FFYSFTCKENLYLVMEYLNGGDMYSMLRNLGCLDED
||||. . .| |||| |.|....|. .|.|.|.|.. .| . || || |.|||   |.||.|.   ..| .  .||.|||| .||.| | ||. |.....
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

MARYYIA-ELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSK
.|. |.| . |||||||||.  |.||||| ||||  .||| .|||| .|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAK

Kinase MAST_c-2.AA SGK 764-862 45 1e-43 132.58 In-house 187-283 (283) Show / Hide
Range on Protein: 764-862
Range on HMM: 187-283/283
Sequence Identity: 45% (45 aa)

GTPDYLAPEILLGTAHGYPADWWSVGVILFEFLTGIPPFNAEDPQMIFENILNRNIPWPNIPGDMSFEAADFIDKLLAEDPNHRLGAK-GAAEVKAHPFF
||| |||||.|..  |.   |||. | .|.|...|.|||   . |  ..||.|  .   .||  || .| | |  ||. ||  |||.| ...|.| ||||
GTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPL---QIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF





Kinase MAST_c-2.AA Akt 764-862 42 6.1e-43 135.05 In-house 164-264 (264) Show / Hide
Range on Protein: 764-862
Range on HMM: 164-264/264
Sequence Identity: 42% (43 aa)

GTPDYLAPEILLGTAHGYPADWWS-VGVILFEFLTGIPPFNAEDPQMIFENILNRNIPWPNIPGDMSFEAADFIDKLLAEDPNHRLG--AKGAAEVKAHP
||| |||||||.|. |. ..|||. .|....|...| ||| ..| .  |..|.| ..  |.     | |. |.| .||  ||..|||   ..| |.|.||
GTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDK-DWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHP

FF
.|
WF

Kinase MAST_c-2.AA PKA 764-862 38 2.4e-33 117.13 In-house 160-263 (263) Show / Hide
Range on Protein: 764-862
Range on HMM: 160-263/263
Sequence Identity: 38% (41 aa)

GTPDYLAPEILLGT-AHGYPADWWSVGVILFEFLTGIPPFNAE--DPQMIFENILNRNIPWPNIPGDMSFEA---ADFIDKLLAEDPNHRLGAKGA--AE
|||.||||||....  || . |||. |.. .|.|.|.|||...  ||  |.| |.|  | .|.    ..  |    |.|.|||. |.. |.| . .    
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPR---HFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVND

VKAHPFF
.| |..|
IKNHKWF

Kinase MAST_c-2.AA MASTL 764-862 33 4.3e-26 86.18 In-house 166-283 (283) Show / Hide
Range on Protein: 764-862
Range on HMM: 166-283/283
Sequence Identity: 33% (41 aa)

GTPDYLAPEILLGTAHGYPADWWS-VGVILFEFLTGIPPFNAEDPQMIFENILNRNIPWPNIPGDMS---------------------FEAADFIDKLLA
||||||.|| ..   ||   |||.  || ..||..|||||. | |.  |.|||.|.. ||     .|                      .. . |..|| 
GTPDYLKPEQDYQQTHGQVVDWWASLGVCFYEFMKGIPPFCDESPCKVFQNILSRDLEWPMGDEQKSTTPYSSKLLKSCFETVASNPEVPVMCLIENLLQ

EDPNHRLGAKGAAEVKAHPFF
 .|. |  |.   .|. | | 
MRPRDRPSAT---DVQQHTFI

Kinase MAST_c-2.AA Pkinase_Tyr 576-722 27 4.7e-20 68.54 Pfam 1-159 (270) Show / Hide
Range on Protein: 576-722
Range on HMM: 1-159/270
Sequence Identity: 27% (44 aa)

FEIIKPISRGAFGRVFLARKR----TTGDLFAIKVLRKADMIRKN-AVESVHAERNILIHA-KNPFLVRFFYSFTCK-EN--LYLVMEYLNGGDMYSMLR
 ...| . .||||.|.... .     |.   |.|.| | .   ..   |.  .| .|. .  ..| .||.    |.. |   .|.||||  .||... ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

N----LGCLDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSK
.     . |.  .   . ..   ..|||.|   |||||   |.|........ .||||..
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR

Kinase MAST_c-2.AA TyrKc 576-862 21 2e-14 10.42 SMART 1-280 (280) Show / Hide
Range on Protein: 576-862
Range on HMM: 1-280/280
Sequence Identity: 21% (68 aa)

FEIIKPISRGAFGRVFLARKRTTGDLFAIKVLRKADMIRKNAVESVHAERNILIHA--KNPFLVRFFYSFTCK-------ENLYLVMEYLNGGDMYSMLR
 . .| . .||||.|.... .      |.|.|..        .|  . | .|. .   ..| .||..   | .       | |..||||  .||  . ||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NLGC-LDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIAHDGHIRLTDFGLSKVGLIN-----STDDLSA---PASRG-AAVAVEKHDSSDSSTKK
. .  |  .   ..        |||||  .|||||   |.|........ .|||||. .        |.|  ..     ...   .              
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR-------------

GRQQKTVGTPDYLAPEILLGTAHGYPADWWSVGVILFEFLT-GIPPFNA-----EDPQMIFENILNRNIPWPNIPGD--------MSFEAADFIDKLLAE
            .||| .         | || || ..| .| | .|         ..| ..|.. ... . .  | .        .. |  . . .  .|
-----------WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQ--PPNDYPMSFVCCPDEMYQIMKQCWHE

DPNHRLGAKGAAEVKAHPFF
||. |   .       | .|
DPEDRPTFSEI-----HECF

Kinase MAST_c-2.AA APH 670-724 15 0.003192 11.87 Pfam 150-205 (248) Show / Hide
Range on Protein: 670-724
Range on HMM: 150-205/248
Sequence Identity: 15% (9 aa)

CLDEDMARYYIAELVLALEYLHSLAVIHRDLKPDNILIA-HDGHIR---LTDFGLSKVG
.. .....  .|.|  ..     ....|.|..|.|...  ...  |   . |.. . .|
DRQWWLWQRLWAWLEAHWP---PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWG

Kinase MAST_c-2.AA APH 578-662 20 1.600579 2.66 Pfam 1-86 (248) Show / Hide
Range on Protein: 578-662
Range on HMM: 1-86/248
Sequence Identity: 20% (19 aa)

IIKPISRGAFGRVFLARKRTTG-DLFAIKVLRKADMIRKNAVESVHAERNILIH-AKNPF--LV-RFFY-----SFTCKENLYLVMEYLNGGDMY
 ..||| |. .|... .    . ...  .. ...      . |..|.|. .| | |....   | | ..     .|  .  ....||.| | | .
WWRPISGGWSNRTYYRTTDD-RPRYV-LRRYPPP-----WWAEELHREHRWLRHLAAHGIPVPVPRVLWGCTDDEFHGW--PWYLMEWLPGEDLW