Gene FAM20B (Human)

FAM20B

Species: Human
Alias: FAM20B
External Links:
Annotation:

Classification

Group: PKL
Family: FJ

Sequence

Name Sequence Type Origin Length Description Download
FAM20B.AA Protein None 409 None Fasta, JSON
FAM20B.NA RNA None 5950 None Fasta, JSON
FAM20B.kin_dom Protein Kinase Domain None 287 None Fasta, JSON

Protein domain

Protein domains of FAM20B.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FJ_kinase FAM20B.AA FJ_kinase 103-389 43 5.4e-179 600.95 In-house 1-351 (351) Show / Hide 
Range on Protein: 103-389
Range on HMM: 1-351/351
Sequence Identity: 43% (151 aa)

YKGTQLKALLILEGGQKVVFKPKRYSRD--HVVEGEPYAGYDRHNAEVAAFHLDRILGFHR--APLVVGRFVNLRTEIKPVA-TEQLLSTFLTVGN--NT
..|||||... ...||...|||..|.||  ||.....|..|||||.|.|||||||||.|..  ||.||||.||..||..||| ...|..||.....  ||
GCGTQLKRMFTFADGQRACFKPMWYPRDQEHVINHFYYQNYDRHNGEIAAFHLDRILNFRWNLAPPVVGRVVNMTTEWYPVATDQELQKTFFISPAKNNT

CFYGKCYY-CRETEPACADG-DIMEGSVTLWLPD--VWPLQKHRHPWGRTYREG-KLARWEYD-----------------ESYCDAVKKTSP-------Y
||||||.. |......|.|. ..||||.|.|||.  .||..|.|||| |||... | | ||.|                 ..||..||...|       |
CFYGKCHWYCDTEHVVCTDWENLMEGSITAWLPQEPFWPRKKWRHPWQRTYHKRHKKAEWETDQIRVRHGLLKRLGAAHQMNYCKEVKQKPPSPSPEEVY

DSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEG----------------ASMLILLDNAKSFGNP----SLDERSILAPLYQCCIIRVSTWNRLNYLK
|.|.||||.||..||||||||.||||||.|....                 ..||..|||.|.||.|    ...|...||||||||..| |||.||....
DHGRRLLDWIDMIVFDYLIGNMDRHHYETFNFQWNARIMERPTHNLHRQPDEGMLVHLDNEKGFGHPYRVLFHWELYHLAPLYQCCMFRRSTWQRLQEFH

NG--------VLKSALKSAMAHDPISPVLSDPHLDAVDQRLLSVLATVKQC
||        .| ......|..||..|||.|.|..|...|.. |...|..|
NGPDVGRRLRRLFELMRESMPRDPLHPVLWDKHYKALQRRIDRVYKHVHHC
DUF1193 FAM20B.AA DUF1193 188-402 52 2e-149 507.48 Pfam 1-234 (234) Show / Hide 
Range on Protein: 188-402
Range on HMM: 1-234/234
Sequence Identity: 52% (122 aa)

FLTV-GNNTCFYGKC-YYCRETEPACA--DGDIMEGSVTLWLPD--VWPLQKHRHPWGRTYREGKLARWEYDESYCDA-VKKTSPYDSGPRLLDIIDTAV
|... .||||||||| |||......|.  ..|.||||.|.||||  .||..|.||||.|||...|.|.||.|..|||. ||...|||.|.|||||||.|.
FFCSPANNTCFYGKCSYYCKTEHAVCGDQNPDMMEGSLTAWLPDLSLWPRKKWRHPWQRTYHKRKKAEWETDPNYCDTYVKQMPPYDHGTRLLDIIDMAI

FDYLIG-------NADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLK--NGVLKSALKSAMAHD---PISPVLS
||.|||       |.||||||.|........||.|||...|||.| ||.||||||||||.||.|||.||....  ...|..... ...||   |..|||.
FDFLIGRFFSVGHNMDRHHYETFEKFGNETFLIHLDNGRGFGNHSHDELSILAPLYQCCMIRRSTWLRLQLFSNPGYRLSEVMRESLSHDPLHPVHPVLT

DPHLDAVDQRLLSVLATVKQCTDQFGMDTVLVED
.||..|.|.||. |..||.||..|.| |.|.|||
EPHYEAMDRRLQIVMQTVEQCIEQHGRDDVIVED