Gene FAM20A (Human)

FAM20A

Species: Human
Alias: FAM20A
External Links:
Annotation:

Classification

Group: PKL
Family: FJ

Sequence

Name Sequence Type Origin Length Description Download
FAM20A.AA Protein None 541 None Fasta, JSON
FAM20A.NA RNA None 2955 None Fasta, JSON
FAM20A.kin_dom Protein Kinase Domain None 296 None Fasta, JSON

Protein domain

Protein domains of FAM20A.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FJ_kinase FAM20A.AA FJ_kinase 217-512 40 4.3e-170 571.38 In-house 1-351 (351) Show / Hide 
Range on Protein: 217-512
Range on HMM: 1-351/351
Sequence Identity: 40% (142 aa)

PSGVHLKLVLRFSDFGKAMFKPMRQQRDEETPVDFFYFIDFQRHNAEIAAFHLDRILDFRR--VPPTVGRIVNVTKEILEVTKNEILQSVFFVSPA-SNV
. | .||....|.|  .|.||||...||.|.....||.....|||.|||||||||||.||.  .||.|||.|| |.|...|.... ||. ||.||| .|.
GCGTQLKRMFTFADGQRACFKPMWYPRDQEHVINHFYYQNYDRHNGEIAAFHLDRILNFRWNLAPPVVGRVVNMTTEWYPVATDQELQKTFFISPAKNNT

CFFAKCPYMCKTEYAVCGNP-HLLEGSLSAFLPSLNLAPRLSVPNPWIRSYTLA-GKEEWEVN-----------------PLYCDTVKQIYP-------Y
||..|| ..|.||..||... .|.|||. |.|| ....|| .. .|| |.|.    |.|||..                 . ||..|||..|       |
CFYGKCHWYCDTEHVVCTDWENLMEGSITAWLPQEPFWPRKKWRHPWQRTYHKRHKKAEWETDQIRVRHGLLKRLGAAHQMNYCKEVKQKPPSPSPEEVY

NNSQRLLNVIDMAIFDFLIGNMDRHHYEMFTKFGD----------------DGFLIHLDNARGFGRH----SHDEISILSPLSQCCMIKKKTLLHLQLLA
....|||..|||..||.|||||||||||.| ....                .|.|.||||..|||..    .|.|...|.||.||||... |. .|| ..
DHGRRLLDWIDMIVFDYLIGNMDRHHYETFNFQWNARIMERPTHNLHRQPDEGMLVHLDNEKGFGHPYRVLFHWELYHLAPLYQCCMFRRSTWQRLQEFH

QA-D-----YRLSDVMRESLLEDQLSPVLTEPHLLALDRRLQTILRTVEGC
.. |     .||...||||.  |.|.|||...|. ||.||.......|. |
NGPDVGRRLRRLFELMRESMPRDPLHPVLWDKHYKALQRRIDRVYKHVHHC
DUF1193 FAM20A.AA DUF1193 305-524 60 1.8e-153 520.94 Pfam 1-234 (234) Show / Hide 
Range on Protein: 305-524
Range on HMM: 1-234/234
Sequence Identity: 60% (142 aa)

FFVSPASNVCFFAKCPYMCKTEYAVCG--NPHLLEGSLSAFLPSLNLAPRLSVPNPWIRSYTLAGKEEWEVNPLYCDT-VKQIYPYNNSQRLLNVIDMAI
||.||| |.||. ||.|.||||.||||  ||...||||.|.||.|.|.|| ....||.|.|.   | |||..| |||| |||..||.. .|||..|||||
FFCSPANNTCFYGKCSYYCKTEHAVCGDQNPDMMEGSLTAWLPDLSLWPRKKWRHPWQRTYHKRKKAEWETDPNYCDTYVKQMPPYDHGTRLLDIIDMAI

FDFLIG-------NMDRHHYEMFTKFGDDGFLIHLDNARGFGRHSHDEISILSPLSQCCMIKKKTLLHLQLLAQADYRLSDVMRESLLED---QLSPVLT
||||||       ||||||||.| |||...|||||||.||||.|||||.|||.||.|||||...|.|.|||.....||||.|||||| .|   ...||||
FDFLIGRFFSVGHNMDRHHYETFEKFGNETFLIHLDNGRGFGNHSHDELSILAPLYQCCMIRRSTWLRLQLFSNPGYRLSEVMRESLSHDPLHPVHPVLT

EPHLLALDRRLQTILRTVEGCIVAHGQQSVIV-D
|||. |.|||||....||| ||. ||...||| |
EPHYEAMDRRLQIVMQTVEQCIEQHGRDDVIVED