Gene AqueK692 (A.queenslandica)

AqueK692

Species: A.queenslandica
Alias: AqueK692
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Unique

Sequence

Name Sequence Type Origin Length Description Download
AqueK692.AA Protein None 623 None Fasta, JSON
AqueK692.kin_dom Protein Kinase Domain None 171 None Fasta, JSON

Protein domain

Protein domains of AqueK692.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DUSP AqueK692.AA DUSP 165-218 37 1.3e-13 47.7 Pfam 1-57 (96) Show / Hide 
Range on Protein: 165-218
Range on HMM: 1-57/96
Sequence Identity: 37% (23 aa)

GDKWYLVDQKWFKQWKEYTGFDSWDQHTAGEPSAHPGPI-D--NNDLFKDPNTN-----NIK
||||||.. ||..|||.| ..|..|          |||| |  |.|...| ..      ..|
GDKWYLISMKWWNQWKQYVYYDNNDNDNM-----RPGPIEDDKNSDILCDHDSCFKYNYQLK
DUSP AqueK692.AA DUSP 161-268 22 6.1e-11 43.6 SMART 1-114 (114) Show / Hide 
Range on Protein: 161-268
Range on HMM: 1-114/114
Sequence Identity: 22% (27 aa)

RLKKGDK-WYLVDQKWFKQWKEYTG--------FDSWDQHTAGEPSAHPGPIDNNDLFKDPN-TNNIKTGSFSRIDTISRVLTVIKQ--QFNIPDTTECR
 .|.||. ||.....|..||..|..        ||||..   |.   .|||||| |.... . | |        . .....   ...     ||  .  .
NWKEGDTRWYCISMRWWRQWQDYVEHQHCCGQAFDSWCMYGEGSHGKFPGPIDNWDIICSHGHTWN--------ANDWRLKWHLYEGCDYVLIPQEVWNY

LWKRYMIND--YELLTNLQQTV
|   | ...  ....... . .
LVRWYGGGPGQEPIMRCVICQG
Kinase AqueK692.AA TKL 294-467 20 3.8e-33 116.46 In-house 1-268 (364) Show / Hide 
Range on Protein: 294-467
Range on HMM: 1-268/364
Sequence Identity: 20% (57 aa)

LGRGAYGVVTEVIVSG----------TTCAAKKLHNIIVQDYTL-------------------------SRFSDEVLLHSHQRHPNIVQLIG-VYYPPR-
.|.|..|.|   .  |          .. | ||..   ..  |.                          ..  |....|  |||||||..| . .||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------SQLPMLVMEYLPL-S-LTQCLEREELPLQMKYSILLDVAKGLCYLHGKR------PPIVHRDLTANNVLLTSSYS--------------AK
         .  ...|||| |  | | . .      .. . .. ||.|.|..||| ..      |||.||||. .|.|. . .               .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

ISDLGVSRLADTFKK------------------HHLTTVPGNAMVMSPEALNHNP--------------SQYYK
|.|.| ||  .. ..                   .. |. |.   |.||.|. ..              ..| .
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSE
Kinase AqueK692.AA TK 288-461 16 4.7e-30 97.33 In-house 1-360 (486) Show / Hide 
Range on Protein: 288-461
Range on HMM: 1-360/486
Sequence Identity: 16% (58 aa)

EETMNELGRGAYG---VVTEVIVSG---------------------------TTCAAKKLH---NIIVQDYTLS------------RFSDEVLLHSH--Q
 .  ..||.|..|   .| . .. |                           |..| | |.   .   ..  .             ..  |  . .|   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNIVQLIGVYYPPRS----------QLPMLVMEYLPL-----SLTQCLE--REE--------------------------------------------
.|||||.|.||   ...          . .|.|||| |.     || . |   |..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LPLQMKYSILLDVAKGLCYLHGKRP----PIVHRDLTANNVLLTSSYS-----------AKISDLGVSR
                               |... .  . ...|.|. ||| |.      .||||| | |.|.....            .||.| | ||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LADTFKKHHLTTVPG------------------------NAMV----MSPEALNHN
     ||    ...  .. .                        ....    |.||.||..
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDR
Kinase AqueK692.AA TKL-Unique 290-465 29 5.6e-26 88.7 In-house 1-205 (290) Show / Hide 
Range on Protein: 290-465
Range on HMM: 1-205/290
Sequence Identity: 29% (60 aa)

TMNELGRGAYGVVTEVIVSGTTCAAKKLH-NIIVQDYTLSRFSDEVLLHSHQR-HPNIVQLIGVYY---PPRSQLPMLVMEYLPL-SLTQCLE-------
  | .|.|.||.|  ..  |.  | |..| |  .    .  |..|| . .  . |||||...|.     .. ...  .||||.|. ||   |        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNM-CIVMEYCPGGSLYDVLHQNNNNNN

----REELPLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSS-----YSAKISDLGVSRLADTFKKHHLT--------TVPGNAMVMSPEALN
      .|..|..... .|.|.|..||| . ||| ||||.  |.|...      ...||.| | |.....  |  ..        |. |..  |.|| |.
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

HNPSQY
 | .||
MNFCQY
Kinase AqueK692.AA Pkinase_Tyr 289-434 28 2.7e-25 86.3 Pfam 2-160 (270) Show / Hide 
Range on Protein: 289-434
Range on HMM: 2-160/270
Sequence Identity: 28% (46 aa)

ETMNELGRGAYGVVTEVIVS------GTTCAAKKLHNIIVQDY-TLSRFSDEVLLHSHQ-RHPNIVQLIGVYYPPRSQ-LPMLVMEYLPL-SLTQCLERE
. . .||.||.|.| . .        ....| |.| .   ..   .  |  |. . ..  .|||||.|.|| .. . .  ...|||| |. .|   | . 
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

-----ELPLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSRL
      |..... .. ...|||. ||. |.  ..|||| | |.|.|..  .||.| | .|.
REDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLARD
Kinase AqueK692.AA LRRK 288-465 24 1.3e-24 83.99 In-house 1-259 (351) Show / Hide 
Range on Protein: 288-465
Range on HMM: 1-259/351
Sequence Identity: 24% (65 aa)

EETMNELGRGAYG-VVTEVIVSG----------------------------TTCAAKKLHNI-----------------------------IVQDYTLSR
 .  ...|||..| .|   .. |                            .. |.||.. .                             .. . ..  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FSD---EVLLHSHQRHPNIVQLIGVYYPPRSQLPMLVMEYLPL-SLTQCLE---REE-------LPLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANN
|.    || . || .|||||.|.|.   |.    ..||||.|. .| . |.   . .       .. ..|. | |..|||. ||| ..|||.||||.  |
FREFRHEVWIMSHLNHPNIVSLKGFCIHPL----CMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPN

VLLTSS------------YSAKISDLGVSR-LADTFKKHHLTTVPGNAMVMSPEALNHN-PSQY
.|| ||            . |||.| | ||    .|..  . .. ||   |.|| .. |  ..|
ILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEY
Kinase AqueK692.AA Dicty4 289-462 29 7.2e-24 76.64 In-house 2-193 (277) Show / Hide 
Range on Protein: 289-462
Range on HMM: 2-193/277
Sequence Identity: 29% (56 aa)

ETMNELGRGAYGVVTEVIVSGTTCAAKKL--HNIIVQDYTLSRFSDEVLLHSHQRHPNIVQLIGVYYPPRSQL--PMLVMEYLPL-SLTQCLER------
 . ...|.|..| |   .. |.  | |||  ||. .  ..|. |  || . .  |||||... |    |||.   .. |.||.|  .|   |        
NIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQ

EELPLQ--MKYS---ILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSR--LADTFKKHHLTTVPGNAMVMSPEALNHNP
.. .|.     .   . .|.|.|. .||.  | |.|||| . | |   .. .|..|.| |.    .. .|  ..|. | .  |.|| . |.|
QSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP
Kinase AqueK692.AA TK-Unique 289-433 28 1.8e-22 74.39 In-house 2-181 (294) Show / Hide 
Range on Protein: 289-433
Range on HMM: 2-181/294
Sequence Identity: 28% (52 aa)

ETMNELGRGAYGVVTEVIVSG-------TTCAAKKLHNIIVQDYTLSRFSDEVLLHSHQR-HPNIVQLIGVYYPPRSQLPMLVMEYLPLS-----LTQCL
|  ...|.||.| |    |.|       ..|.| |.... ..| . . | .|  ....   ||||||..|.   .  . .|..|||.| .     | .| 
EVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD-EPWMIIMEYCPCGNLQHYLRTCR

-----------------------EREELPLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSR
                       ..|.. ..  |... ..|.|. ||.. |  |||||| | |||||. . .||.|.| .|
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMAR
Kinase AqueK692.AA STE 288-432 20 9.1e-21 70.14 In-house 1-194 (359) Show / Hide 
Range on Protein: 288-432
Range on HMM: 1-194/359
Sequence Identity: 20% (42 aa)

EETMNELGRGAYGVVTEVIVS-----------------GTTCAAKKLH---------------NIIVQDYTLSRFSDEVLLHSHQR--HPNIVQLIGVYY
 | . ..|.||.|.|   .                   |. .| |...               . ....  . ..  |. .... .  |||||. .| |.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

---PP---RSQLPMLVMEYLP-LSLTQCLER-----EELP----------LQMKYSILLDVAKG-LCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLG
   ..   ...|  ..|||..  ||.. ...     ..|.           .    |. .. || | ||| ..  |.|||. . |.||     .|..| |
KEGHNHKNDDEL-WICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL-----VKLCDFG

VS
|.
VC
Kinase AqueK692.AA DRK 292-441 36 4.6e-20 64.68 In-house 5-153 (258) Show / Hide 
Range on Protein: 292-441
Range on HMM: 5-153/258
Sequence Identity: 36% (57 aa)

NELGRGAYGVVTEVIVSGTTCAAKKLHNIIVQ-DYTLSRFSDEVLLHSHQRHPNIVQLIGVYYPPRSQLPMLVMEYLPL-SLTQCLEREELPLQ--MKYS
|  ||| || |      ||  | |.| |  .     |. |  |. | .  |||||.| .|    | .  .  .|||.|. || . |  | . ..     .
NRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPD--ICICMEYMPRGSLYNILHDESIEMDWPLMKQ

ILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSRLADT-FKKH
. .|.|||. |||.  | |.||||   | |   ..  |..| | |    | ||||
MMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLS----TRFKKH
Kinase AqueK692.AA MLK 288-471 23 1.5e-19 64.54 In-house 1-218 (291) Show / Hide 
Range on Protein: 288-471
Range on HMM: 1-218/291
Sequence Identity: 23% (52 aa)

EETMNELGRGAYGVVTEVIVSGTT-----CAAKKLHNIIVQDYTLS-----RFSDEVLLHSHQRHPN----IVQLIGV-YYPPRSQLPMLVMEYLPL-SL
 ..   .| |..|.|      ...      | |. .  |  |   .      |  |. . .. .|||    |.|. ||   ||  .   .||||..  ||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP--CHFCIVMEYCEGGSL

TQCLEREE---------------LPLQMKYSILLDVAKGLCYLHG-KRPPIVHRDLTANNVLLTS------SYSAKISDLGVSRLADTFKKHH---LTTV
   |  ..                ... . .. |..|.|. |||  ...||.||||   |.|..          .||.| |.||    .....    .  
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR----DWHQMCTNMMSN

PGNAMVMSPEALNHNPSQYYKNFVD
.|..  |.||..   ... |   .|
AGTYAWMAPEVIQQFRCEKYSEKCD
Kinase AqueK692.AA CZAK 289-434 28 3e-18 62.99 In-house 2-171 (279) Show / Hide 
Range on Protein: 289-434
Range on HMM: 2-171/279
Sequence Identity: 28% (49 aa)

ETMNELGRGAYGVVTEVIVSGTTCAAKKLHNIIVQDYTL----SRFSDEVLLHSHQRHPNIVQLIGVYYPPRSQLPMLVMEYLP-LSLTQCL-EREELPL
.   . |.| .| |      |.  | |..| .   . .       |  ||   |  .|||.|| .|.       .   |||.    || . | ..  . .
KFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYHK

Q---MKYSILLDVAKGLCYLHG-KRP-PIVHRDLTANNVLLTSSYS-------------AKISDLGVSRL
|   .. .. .|.|.|  |||.  .| ||.||||.  |.|| .||              .||.| | ||.
QNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSRE
Kinase AqueK692.AA Pkinase 288-446 23 3.1e-17 62.04 Pfam 1-171 (293) Show / Hide 
Range on Protein: 288-446
Range on HMM: 1-171/293
Sequence Identity: 23% (42 aa)

EETMNELGRGAYGVVTEVIVSGTTC-----AAKKLHNIIVQDYTLSRFSDEVLLHSHQRHPNIVQLIGVYYPPRSQLPMLVMEYLPL-----SLTQCLE-
 ..   .|.|..|.| . .  || .       || |.   .|.|. |   |. .. . .|||||.|.....   .. . .||||..      .|   .. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

REELPL--QMKY--SILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSA----KISDLGVSRLADTFKKHHLTTV
... ..  ...   .... ...|| |.| .   |.||||   |.|. . .      ||.| |.....|. ... .||.
WRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTF
Kinase AqueK692.AA S_TKc 288-550 16 2.4e-15 48.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 288-550
Range on HMM: 1-231/231
Sequence Identity: 16% (50 aa)

EETMNELGRGAYGVVTEVIV--SGTTCAAKKLHNIIVQDYTLSRFSDEVLLHSHQRHPNIVQLIGVYYPPRSQLPMLVMEYLPL---SLTQCLEREE---
 | ....|.||.|.|  ..   .|  .| |...          ..  |. .... .|||||.|..|..    .   .||||..    .| . ...     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LPLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSRLADTFKKHHLTTVPGNAMVMSPEALNHNPSQYYK--------
    .|  .  ...  ....| |.| .   |.||||   |.||..    ||.| |..|.         ||. |    |.|| |     .| |        
LRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL-----GYGKCKCDWWSC

-----------NFVDSTSEELKNNLMEDKNYTLLPEAAWSLLVSWYGLSVGSRSIVKNVEEHGVHKKLRVEVYLIELKMCVHPN----SINIKT------
              . . ... ....                                          .    .|.  ... |.       . .      
GCILYEMLCGYPPFP-QMQMMFKKIG-----------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-YSFS
   . 
CHPWF
Kinase AqueK692.AA TyrKc 288-524 21 2.6e-14 8.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 288-524
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

EETMNELGRGAYGVVTEVIVSGTTCAAKKLHNIIVQDYTLSRFSDEVLLHSHQ--RHPNIVQLIGVYYPP-----RSQLPMLVMEYLPL-SLTQCLEREE
 .   .||.||.|.| . . . ...| |.|..       .  | .|  . ..   .|||||.|.||   .      .. .|.|||| |. .| . | . .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LPLQMKYSILLDVAKGLCYLHGKRPPIVHRDLTANNVLLTSSYSAKISDLGVSRLADTF------KKHHLTTV--PGNAMV----MSPEALNHN----
  |... . |. ...|.|  ||| |  ...|||| | |.|... . .|||| | ||  .        |.   ..    |..|.    |.||..|..    
PKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

-----------------PSQYYKNFVD--STSEELKNNLMED---KNYTL--------LPEAAWSLLVSWYGLSVGSRSIVKNVEEHGVHKKL
                   | | . .    . .|. .....    .             |..  ..  .       .|   ...     |...
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-----HECF
Kinase AqueK692.AA DUSP 459-517 31 8.8e-12 41.58 Pfam 45-96 (96) Show / Hide 
Range on Protein: 459-517
Range on HMM: 45-96/96
Sequence Identity: 31% (19 aa)

NHNPSQYYKNFVDSTSEELKN-NLMEDKNYTLLPEAAWSLLVSWYGLSVGSRSIVKNVEE
.|. ...|         .||. || |.| |...||..| .|..|||.  |.  |. .| .
DHDSCFKY-------NYQLKPHNLQEGKDYVIVPEEVWNFLYQWYGC-EGGPPIPRKVIC
Kinase AqueK692.AA DUSP 431-519 18 64.268716 3.47 SMART 1-114 (114) Show / Hide 
Range on Protein: 431-519
Range on HMM: 1-114/114
Sequence Identity: 18% (23 aa)

VSRLADT---------FKKHHLTTV-----------------------PG---NAMVMSPEALNHNPSQYYKNFVDSTSEELKNNLMEDKNYTLLPEAAW
 ... ||         ...   ..                        ||   |   . ..    |          . ...||  | |.  |.|.|...|
NWKEGDTRWYCISMRWWRQWQDYVEHQHCCGQAFDSWCMYGEGSHGKFPGPIDNWDIICSHGHTWN----------ANDWRLKWHLYEGCDYVLIPQEVW

SLLVSWYGLSVGSRSIVKNVEEHG
  ||.|||.  |.  |...| ..|
NYLVRWYGGGPGQEPIMRCVICQG