Gene AqueK642 (A.queenslandica)

AqueK642

Species: A.queenslandica
Alias: AqueK642
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH498

Sequence

Name Sequence Type Origin Length Description Download
AqueK642.AA Protein None 423 None Fasta, JSON
AqueK642.kin_dom Protein Kinase Domain None 225 None Fasta, JSON

Protein domain

Protein domains of AqueK642.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK642.AA TKL 1-226 21 1.2e-40 141.34 In-house 66-364 (364) Show / Hide 
Range on Protein: 1-226
Range on HMM: 66-364/364
Sequence Identity: 21% (65 aa)

ETTLKKFNEEILLHSQQRHPNIVQLIG-VYYPPR----------SKVPMLVMEYLPF-TLRESLEHHKLPLQMKYSILSDVAKGLCYLHGKR------PA
.   ....|||...|. |||||||..| . .||           .. ...|||| |  .|.. |      .. . ..  |.|.|..||| ..      |.
SWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPP

IVHRDLTANNVLLTPLYS--------------AKISDLGVSRLIDKFK-----------------SHQQLTQVPGNAIVMPPEALATKP-----------
|.||||. .|.|.   .               .||.|.| || ... .                 .....  . |.   |.||.|  ..           
IIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEF

----VYNEKVDVFTYGCLILHVLTCQFPEP-TDAFVQYFM----FWQSKVAEWDRRSKYI---------QKIPEDEKDFLPLAKQCLQDNPSTRPDMSQV
     |.||.||. .| ..  .||.. |.   . . ..|.     ....|..  .|             .. |   ...  |...| . .|. || ....
CKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEI

LQSV
|.  
LKRL
Kinase AqueK642.AA TK 9-155 16 2e-26 84.96 In-house 92-384 (486) Show / Hide 
Range on Protein: 9-155
Range on HMM: 92-384/486
Sequence Identity: 16% (49 aa)

EEILLHSQQRHPNIVQLIGVYYPPRS----------KVPMLVMEYLPFT-----LRESLEHHK-------------------------------------
.....||  .|||||.|.||   ...          . .|.|||| |       ||. |  ..                                     
MKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESN

----------------------------------------LPLQMKYSILSDVAKGLCYLHGKRP----AIVHRDLTANNVLLTPLYS-----------A
                                        |... .  .  ..|.|. ||| |.      .||||| | |.|..  .            .
SPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVC

KISDLG--------VSRLIDK--FKSHQQLTQVPGNAIV-----------------------MPPEALATKP--------VYNEKVDVFTYGCLI
||.| |         .| |..      ..   .....                         |.||.|...         .. .| ||. .|.|.
KIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLM
Kinase AqueK642.AA TKL-Unique 4-152 28 6.1e-26 88.56 In-house 39-215 (290) Show / Hide 
Range on Protein: 4-152
Range on HMM: 39-215/290
Sequence Identity: 28% (50 aa)

LKKFNEEILLHSQQR-HPNIVQLIGVYYPPRSKVP--MLVMEYLPF-TLRESLE-----------HHKLPLQMKYSILSDVAKGLCYLHGKRPAIVHRDL
...|..|. . .  . |||||...|.      . |   .||||.|  .|.. |            ..||..|.....  |.|.|..||| . | | ||||
MQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDL

TANNVLLTPL-----YSAKISDLGVSRLIDKF--KSHQQL-----TQVPGNAIVMPPEALATK-PVYNEKVDVFTYG
.  |.|..       ...||.| | |.. .|   ..   .     . . |... |.|| |      |.||.||. .|
KSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFG
Kinase AqueK642.AA LRRK 18-164 31 2.3e-23 79.51 In-house 115-282 (351) Show / Hide 
Range on Protein: 18-164
Range on HMM: 115-282/351
Sequence Identity: 31% (55 aa)

RHPNIVQLIGVYYPPRSKVPMLVMEYLPF-TLRESLEHHK----------LPLQMKYSILSDVAKGLCYLHGKRPAIVHRDLTANNVLL---T-------
.|||||.|.|.   |.    ..||||.|. .| . |...|          .. ..|. |  ..|||. ||| ..| |.||||.  |.||   .       
NHPNIVSLKGFCIHPL----CMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNY

--PLYSAKISDLGVSRLIDKFKSHQQLTQVPGNAIVMPPEALA-T-KPVYNEKVDVFTYGCLILHVLTCQ-FP
  . . |||.| | ||.  .   .  .  . || . | || .  . . .|.||||.. .| .. . || | .|
PNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase AqueK642.AA Dicty4 1-152 31 8.4e-22 69.64 In-house 39-204 (277) Show / Hide 
Range on Protein: 1-152
Range on HMM: 39-204/277
Sequence Identity: 31% (54 aa)

ETTLKKFNEEILLHSQQRHPNIVQLIGVYYPPRSKV--PMLVMEYLPFTLRESLEHH---------KLP----LQ-MKYSILSDVAKGLCYLHGKRPAIV
| .|. |  |. . .. |||||... |    |||.   .. |.||.| .  .|| |          ||.    .. |.. .  |.|.|. .||.  | |.
ENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAF--DAARGMNWLHCCNPVII

HRDLTANNVLLTPLYSAKISDLGVSRLIDKFKSHQQ-LTQVPGNAIVMPPEALATKPVYNEKVDVFTYG
|||| . | |    . .|..|.| |... | ..|.. .. . | .  | || .. .| ||||.||. .|
HRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP-YNEKADVYSFG
Kinase AqueK642.AA Pkinase_Tyr 18-155 30 3.6e-21 72.34 Pfam 62-204 (270) Show / Hide 
Range on Protein: 18-155
Range on HMM: 62-204/270
Sequence Identity: 30% (46 aa)

RHPNIVQLIGVYYPPRSK-VPMLVMEYLPF-TLRESLEHH-----KLPLQMKYSILSDVAKGLCYLHGKRPAIVHRDLTANNVLLT-PLYSAKISDLGVS
.|||||.|.|| .. .    ...|||| |   |.. |  |     .|..... ..  ..|||. ||. |.  ..|||| | |.|.| ..  .||.| | .
HHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENN-VVKICDFGLA

RLIDKFKSHQQLTQVPGNAIV----MPPEALATKPVYNEKVDVFTYGCLI
|.|  ..  .  ... |.. .    |.||.....  ...| ||  .| |.
RDI--YNDDYY-YRKRGGGKLPIKWMAPECINYGK-FTTKSDVWSFGVLM
Kinase AqueK642.AA MLK 1-164 24 3e-20 67.04 In-house 46-235 (291) Show / Hide 
Range on Protein: 1-164
Range on HMM: 46-235/291
Sequence Identity: 24% (48 aa)

ETTLKKFNEEILLHSQQRHPN----IVQLIGV-YYPPRSKVPMLVMEYLPF-TLRESLEHHK---------------LPLQMKYSILSDVAKGLCYLHG-
..  ..|..|. . .  .|||    |.|. ||   ||  .   .||||...  | . |   .                ... . ..  ..|.|. |||  
YCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP--CHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSM

KRPAIVHRDLTANNVLLTP------LYSAKISDLGVSRLIDKFKSHQQ-LTQVPGNAIVMPPEAL--ATKPVYNEKVDVFTYGCLILHVLTCQFP
....|.||||   |.|..          .||.| |.||   .......  .  .|... | ||..  .    |.||.||. .| ..  .||.. |
APKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR---DWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase AqueK642.AA Ciliate-E2 19-224 16 5.2e-20 65.36 In-house 91-361 (365) Show / Hide 
Range on Protein: 19-224
Range on HMM: 91-361/365
Sequence Identity: 16% (49 aa)

HPNIVQLIGVYYPPRSKVPMLVMEYLPF-TLRE------SLEHHKLP------LQMKYSILSDVAK---------------GLCYLHGKRPAIVHRDLTA
||||.... ...    .   |||||.   .|..        ..|...      ..    |   ...               .| ||| | . |.|||.  
HPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKP

NNVLLTPLYSAKISDLGVSRLIDKF------KSHQQLTQVPG------------------------NAIVMPPEALATKPV--------YNEKVDVFTYG
.|.|.      ||.|.| |. .|..      |..... .  .                        ..  |.|| |  |.         |..|.|..  |
ENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLG

CLILHVLTCQFPEPTDAFVQYFMFWQSKVAEWDRRSKYIQKIPEDEK--------------DFLPLAKQ-----------CLQDNPSTRPD-MSQVLQ
...   |. ..|                      . .  .||  ...              ... . ..           .|| .|. |.. ..|.|.
VILYEMLFGKPPF--------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase AqueK642.AA Pkinase 10-226 20 1.4e-19 70.33 Pfam 50-293 (293) Show / Hide 
Range on Protein: 10-226
Range on HMM: 50-293/293
Sequence Identity: 20% (54 aa)

EILLHSQQRHPNIVQLIGVYYPPRSKVPMLVMEYLPF-----TLRESLE---HHKL--PLQMKYSILSDVAKGLCYLHGKRPAIVHRDLTANNVLLTPLY
|| ..   .|||||.|.....   .. . .||||..       | . ..   | ..  . .   ...  ...|| |.| .   |.||||   |.|.   .
EIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNG

SA----KISDLGVSRLIDKFKSHQQLTQVPGNAIVMPPEALATKPVYNEKVDVFTYGCLILHVLTCQFPEPTDAFVQYFMFWQS----KVAEWDRRSKYI
      ||.| |.....|   . . .| . |    |.|| . . . |  |||.. .||..  .|.            .. |...    . .. . . . |
HIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-----------GRPPFPGHCWHDN-HDQMQMICRI

QK--IPEDE------------------------KDFLPLAKQCLQDNPSTRPDMSQVLQS--V
 .  ...|.                        .... . | ||. .|. ||   |.||.  .
MGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK642.AA HH498 59-164 37 4.9e-18 53.39 In-house 120-225 (284) Show / Hide 
Range on Protein: 59-164
Range on HMM: 120-225/284
Sequence Identity: 37% (40 aa)

LQMKYSILSDVAKGLCYLHG-KRPAIVHRDLTANNVLLTPLYSAKISDLGVSRLIDKFKSHQQLTQVPGNAIVMPPEALATKPVYNEKVDVFTYGCLILH
|| |  |  |||.|  |||    . |.||||.  |.|.     |.. | | || .        .|  |||   | ||       | .||||| |.  |  
LQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMH-DDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWE

VLTCQFP
 .|   |
MHTREVP
Kinase AqueK642.AA TK-Unique 18-155 28 7.2e-18 58.3 In-house 62-229 (294) Show / Hide 
Range on Protein: 18-155
Range on HMM: 62-229/294
Sequence Identity: 28% (48 aa)

RHPNIVQLIGVYYPPRSKVPMLVMEYLPFT-----LRESLEHHKLP---------------------LQMK--YSILSDVAKGLCYLHGKRPAIVHRDLT
.||||||..|.   .    .|..|||.|       ||..   .. .                     ...|  |... ..|.|. ||.. |  |||||| 
DHPNIVQCLGCCTKSD-EPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLC

ANNVLLTPLYSAKISDLGVSRLIDKFKSHQQL-TQVPGNAIVMPPEALA--TKPVYNEKVDVFTYGCLI
| |||||  . .||.|.| .| ... . ..   .| .     |.||.|   ... ...| ||  .|.|.
ARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLM
Kinase AqueK642.AA DRK 4-152 33 3.1e-16 51.51 In-house 41-189 (258) Show / Hide 
Range on Protein: 4-152
Range on HMM: 41-189/258
Sequence Identity: 33% (51 aa)

LKKFNEEILLHSQQRHPNIVQLIGVYYPPRSKVPMLVMEYLPF-TLRESLEHHKLPLQ--MKYSILSDVAKGLCYLHGKRPAIVHRDLTANNVLLTPLYS
|. |  || | .| |||||.| .|    | .  .  .|||.|   |   |   .. ..     ..  |.|||. |||.  | |.||||   | |    . 
LNEFHREINLMCQLRHPNICQFMGTCNNPPD--ICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQ

AKISDLGVSRLIDKFKSHQQLTQVPGNAIVMPPEALATKPVYNEKVDVFTYG
 |..| | |    | |.|       |      || |.  . | || ||. ..
VKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQR-YTEKADVYSFA
Kinase AqueK642.AA S_TKc 3-231 22 5.7e-15 42.6 SMART 19-231 (231) Show / Hide 
Range on Protein: 3-231
Range on HMM: 19-231/231
Sequence Identity: 22% (57 aa)

TLKK-------------FNEEILLHSQQRHPNIVQLIGVYYPPRSKVPMLVMEYLPF---TLRESLEHHK-------LPLQMKYSILSDVAKGLCYLHGK
. ||             .  || .... .|||||.|..|..    .   .||||..    .|.. .....       .|  .  ...  ....| |.| .
RHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH

RPAIVHRDLTANNVLLTPLYSAKISDLGVSRLIDKFKSHQQLTQVPGNAIVMPPEALATKPVYNE-KVDVFTYGCLILHVLTCQFPEPTDAFVQYFMFWQ
   |.||||   |.||.     ||.| |..|..         | . |    |.|| |     |.  |.|.   ||..   |. . | |     |..| ..
--GIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFK

SKVAEWDRRSKYIQKIPEDEKDFLPLAKQCLQDNPSTRPDMSQVLQ----SVEEKCT
  .                 .... . ..||| .|. ||   ..||           
KIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK642.AA TyrKc 2-226 24 2.1e-14 10.36 SMART 1-280 (280) Show / Hide 
Range on Protein: 2-226
Range on HMM: 1-280/280
Sequence Identity: 24% (69 aa)

TTLKK-------------------------------FNEEILLHSQQ--RHPNIVQLIGVYYPP-----RSKVPMLVMEYLPF-TLRESLEHHK--LPLQ
 ||.|                               | .|. . ..   .|||||.|.||   .      .. .|.|||| |   |.. |  |.  |...
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

MKYSILSDVAKGLCYLHGKRPAIVHRDLTANNVLLTPLYSAKISDLGVSRLIDKF----KSHQQLTQ---VPGN--AIV--MPPEALATKPVYNEKVDVF
 . |.  ..|.|  ||| |   ..|||| | |.|..  . .|||| | || |.       |..  ..     |.    .  |.||..  . ....| ||.
DLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDVW

TYGCLILHVLT-CQFPEPTDAFVQYFMFWQSKVAEWDRRSKYIQKIPE--------DEKDFLPLAKQCLQDNPSTRPDMSQVLQSV
 .| ..  ..| .| | | ...    |   . | |. .. ..  . |.          ..   . ||| . .|. || .|.. .  
SFGVCMWEIFTYGQQPYPGMIQQ---MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK642.AA MLK 206-226 38 4.8e-05 13.59 In-house 271-291 (291) Show / Hide 
Range on Protein: 206-226
Range on HMM: 271-291/291
Sequence Identity: 38% (8 aa)

KQCLQDNPSTRPDMSQVLQSV
||| ...|. ||...|..|  
KQCWNQDPHKRPSFRQIVQHL
Kinase AqueK642.AA DRK 201-228 28 0.000117 11.74 In-house 231-258 (258) Show / Hide 
Range on Protein: 201-228
Range on HMM: 231-258/258
Sequence Identity: 28% (8 aa)

FLPLAKQCLQDNPSTRPDMSQVLQSVEE
.  | . |.  .|. || | ..|.  | 
YIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase AqueK642.AA TK 204-226 34 0.000463 8.66 In-house 464-486 (486) Show / Hide 
Range on Protein: 204-226
Range on HMM: 464-486/486
Sequence Identity: 34% (8 aa)

LAKQCLQDNPSTRPDMSQVLQSV
| .|| . .|. ||..||...  
LMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK642.AA Dicty4 206-228 24 0.000741 8.94 In-house 253-277 (277) Show / Hide 
Range on Protein: 206-228
Range on HMM: 253-277/277
Sequence Identity: 24% (6 aa)

KQCLQDNPSTRPDMSQVLQS--VEE
. |.  .|. || .....|    |.
QWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK642.AA LRRK 193-228 23 0.002292 7.75 In-house 309-351 (351) Show / Hide 
Range on Protein: 193-228
Range on HMM: 309-351/351
Sequence Identity: 23% (10 aa)

KIP---EDEK----DFLPLAKQCLQDNPSTRPDMSQVLQSVEE
.||   . ..    ... | ..| | .|  || .||...  ..
TIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK642.AA TK-Unique 206-226 33 0.002904 7.25 In-house 274-294 (294) Show / Hide 
Range on Protein: 206-226
Range on HMM: 274-294/294
Sequence Identity: 33% (7 aa)

KQCLQDNPSTRPDMSQVLQSV
|.|.|..|. ||. .|...  
KSCWQWEPEERPSFRQIKHRL
Kinase AqueK642.AA TKL-Unique 206-226 28 0.022504 4.4 In-house 270-290 (290) Show / Hide 
Range on Protein: 206-226
Range on HMM: 270-290/290
Sequence Identity: 28% (6 aa)

KQCLQDNPSTRPDMSQVLQSV
.||  ..|| ||  .... . 
QQCWHHDPSQRPSFDEIIHRL
Kinase AqueK642.AA HH498 199-226 25 0.02516 2.73 In-house 257-284 (284) Show / Hide 
Range on Protein: 199-226
Range on HMM: 257-284/284
Sequence Identity: 25% (7 aa)

KDFLPLAKQCLQDNPSTRPDMSQVLQSV
.  . |  .| . .|. ||| .|..   
HHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase AqueK642.AA Pkinase_Tyr 206-226 33 1.156422 2.87 Pfam 250-270 (270) Show / Hide 
Range on Protein: 206-226
Range on HMM: 250-270/270
Sequence Identity: 33% (7 aa)

KQCLQDNPSTRPDMSQVLQSV
||| . .|. || .|....  
KQCWHYDPEDRPTFSEIHEQL