Gene AqueK473 (A.queenslandica)
AqueK473
Species: A.queenslandica
Alias: AqueK473
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK473.AA | Protein | None | 136 | None | Fasta, JSON |
| AqueK473.kin_dom | Protein Kinase Domain | None | 93 | None | Fasta, JSON |
Protein domains of AqueK473.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | AqueK473.AA | IRAK | 36-126 | 36 | 6.2e-31 | 106.93 | In-house | 1-92 (317) | Show / Hide |
Range on Protein: 36-126 Range on HMM: 1-92/317 Sequence Identity: 36% (35 aa) FNKTNKLGEGGFGPVFRGELLSTD--VAIKVLRRTKPGDKGASDLADEQFDA---EIQILSKFRHPNLVTLLGYSNDPGLPRCLIYEFMVNGTLED |.| |..|||||| |.||.. |. .|.| |. .. . . ...|.. |.......||||.| |.||. ... . ||.|..| ||.||| FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEH---WQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCH-CLVYPYMPNGSLED |
|||||||||
| Kinase | AqueK473.AA | TKL | 42-128 | 20 | 7.5e-20 | 68.16 | In-house | 1-129 (364) | Show / Hide |
Range on Protein: 42-128
Range on HMM: 1-129/364
Sequence Identity: 20% (27 aa)
LGEGGFGPVFRGELLS----------TDVAIKVLRR---TKPGDKG-----------------ASDLADEQFDAEIQILSKFRHPNLVTLLGYSNDPGL-
.|.|||| |..|.. .|||.|.... . .. . . ... || ..|..||||.| ..||...|.
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
-----------PRCLIYEFMVNGTLEDAL
|...|.. .|.|.. |
CVCMHPVGPWGQLCIVMEYCPGGSLLHYL
|
|||||||||
| Kinase | AqueK473.AA | MLK | 36-128 | 25 | 1.9e-19 | 64.21 | In-house | 1-101 (291) | Show / Hide |
Range on Protein: 36-128 Range on HMM: 1-101/291 Sequence Identity: 25% (26 aa) FNKTNKLGEGGFGPVFRGELLSTD-----VAIKVLRRTKPGDKGASDLADEQFDAEIQILSKFRHPN----LVTLLGYSNDPGLPRCLIYEFMVNGTLED .. ..|.|.|| |..|. .| ||.| | .. ||. .. ...|. |. .|....||| . ..| ...|. . |.. |.. .| | . IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN AL | VL |
|||||||||
| Kinase | AqueK473.AA | Pkinase_Tyr | 36-126 | 32 | 2.1e-19 | 66.35 | Pfam | 1-96 (270) | Show / Hide |
Range on Protein: 36-126 Range on HMM: 1-96/270 Sequence Identity: 32% (33 aa) FNKTNKLGEGGFGPVFRGELL------STDVAIKVLRRTKPGDKGASDLA--DEQFDAEIQILSKF-RHPNLVTLLGYSNDPGLP--RCLIYEFMVNGTL . ||||| || |..|.. ..||.|.|. ||.. . | | .|..|.... .|||.| |.| | | | ... |.| .| | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE------GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL ED | LD |
|||||||||
| Kinase | AqueK473.AA | TK-Unique | 36-126 | 30 | 9.8e-18 | 57.83 | In-house | 1-94 (294) | Show / Hide |
Range on Protein: 36-126 Range on HMM: 1-94/294 Sequence Identity: 30% (30 aa) FNKTNKLGEGGFGPVFRGELLS--------TDVAIKVLRRTKPGDKGASDLADEQFDAEIQILSKFR-HPNLVTLLGYSNDPGLPRCLIYEFMVNGTLED .. ...||| ||.|.|||. . . ||.| |.. .|.|. . .| |||.... |||.|..||.. ... | ..|.|.. .|.|.. LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKD------NATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQH |
|||||||||
| Kinase | AqueK473.AA | TK | 36-128 | 19 | 2.1e-17 | 54.15 | In-house | 1-150 (486) | Show / Hide |
Range on Protein: 36-128
Range on HMM: 1-150/486
Sequence Identity: 19% (29 aa)
FNKTNKLGEGGFG---PVFRGELLS---------------------------TDVAIKVLRRTKPGDKGASDLADEQ----------FDAEIQILS--KF
.||||| || |..||. . |.||.|.|. . . .. . ... . . .|..... ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
RHPNLVTLLGYSNDPG-----------LPRCLIYEFMVNGT----LEDAL
.|||.| |.|.. ... | ... |.| .| | | |
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYL
|
|||||||||
| Kinase | AqueK473.AA | TKL-Unique | 38-129 | 32 | 2.7e-17 | 57.71 | In-house | 1-92 (290) | Show / Hide |
Range on Protein: 38-129 Range on HMM: 1-92/290 Sequence Identity: 32% (31 aa) KTNKLGEGGFGPVFRGELLSTDVAIKVLRRTKPGDKGASDLADEQFDAEIQILSKFR-HPNLVTLLGYSND---PGLPRCLIYEFMVNGTLEDALD ||.||||.|.|..|. ...||||.. .| . | . | |. ...|.. |||.|.. ||. | . .|.. |.. |.| | |. FWNKIGEGGYGQVYKGKWRGYPVAIKQF---HP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLH |
|||||||||
| Kinase | AqueK473.AA | Dicty4 | 36-109 | 29 | 3.5e-16 | 50.63 | In-house | 1-75 (277) | Show / Hide |
Range on Protein: 36-109 Range on HMM: 1-75/277 Sequence Identity: 29% (23 aa) FNKTNKLGEGGFGPVFRGELLSTDVAIKVLRRTKPGDKGASDLADEQFDAEIQILSKFRHPNLVTLLGYSN----DPG |.....|.|.|| |..| ..||.|.| .. .. .. | . | .|. |..| ||||.....|... || INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFD-ENMLNE--FRKEVHIMCKIRHPNICLFMGACTAPRSHPG |
|||||||||
| Kinase | AqueK473.AA | UTK | 36-128 | 23 | 6.8e-15 | 47.4 | In-house | 1-101 (296) | Show / Hide |
Range on Protein: 36-128
Range on HMM: 1-101/296
Sequence Identity: 23% (26 aa)
FNKTNKLGEGGFGPVFRGEL-------LSTDVAIKVLRRTKPGDKGASDLADEQFDA----------EIQILSKFR-HPNLVTLLGYSNDPGLPRCLIYE
..||.| || |..... . |||.||.. .. ...|. . |.|....|. |||.. |.|. . . ....|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ---------HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTE
FMVNGTLEDAL
.|.|| | . |
YMENGDLRSYL
|
|||||||||
| Kinase | AqueK473.AA | Src | 36-126 | 32 | 1.6e-14 | 45.74 | In-house | 1-83 (255) | Show / Hide |
Range on Protein: 36-126 Range on HMM: 1-83/255 Sequence Identity: 32% (30 aa) FNKTNKLGEGGFGPVFRGELLS-TDVAIKVLRRTKPGDKGASDLADEQFDAEIQILSKFRHPNLVTLLGYSNDPGLPRCLIYEFMVNGTLED . |||.| || |. | |.||.|.|.. .. |.| .|.||. |.||..|| |. . | . |.| .| | | IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGT--------MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEE-PIYIVTEYMSHGSLLD |
|||||||||
| Kinase | AqueK473.AA | Pkinase | 36-128 | 22 | 1e-12 | 46.01 | Pfam | 1-95 (293) | Show / Hide |
Range on Protein: 36-128 Range on HMM: 1-95/293 Sequence Identity: 22% (24 aa) FNKTNKLGEGGFGPVFRGELLSTD--VAIKVLRRTKPGDKG------ASDLADEQFDAEIQILSKFRHPNLVTLLGYSNDPGLPRCLIYEFMVNG----T . . |.|.|.|| |... .| ||.|.... . .. . .||||. ...||| |.|... | . ... |.. .| YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---------SEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMD LEDAL | | . LFDYI |
|||||||||
| Kinase | AqueK473.AA | LRRK | 36-124 | 18 | 1.1e-12 | 41.2 | In-house | 1-142 (351) | Show / Hide |
Range on Protein: 36-124 Range on HMM: 1-142/351 Sequence Identity: 18% (27 aa) FNKTNKLGEGGFG-PVFRGELLS----------------------------TDVAIKVLRRT----------------------KPGDKGASDLADEQFD . . ...|.|||| .|.|... . ..||||.. |. .. . .... LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVED-MDQNHEDCCR A------EIQILSKFRHPNLVTLLGYSNDPGLPRCLIYEFMVNGTL | |. |.|...|||.| |.|.. . |.|.. |.. .|.| AFREFRHEVWIMSHLNHPNIVSLKGFCIH---PLCMVMEYAPHGDL |
|||||||||