Gene AqueK457 (A.queenslandica)

AqueK457

Species: A.queenslandica
Alias: AqueK457
External Links:
Annotation:

Classification

Group: TK
Family: TK-Unique

Sequence

Name Sequence Type Origin Length Description Download
AqueK457.AA Protein None 889 None Fasta, JSON
AqueK457.kin_dom Protein Kinase Domain None 296 None Fasta, JSON

Protein domain

Protein domains of AqueK457.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
IG AqueK457.AA IG 148-232 11 0.062586 7.71 SMART 1-58 (58) Show / Hide 
Range on Protein: 148-232
Range on HMM: 1-58/58
Sequence Identity: 11% (10 aa)

AQQLNGTGGQDIMKKFVVFGAPDPVLSIAKEASNGDYIPINDNRITLSLTNFTFTSLKLSDA---GQYKIWGNNSHGDSSF--TFRINVS
 . . .  |...  .  |                         .|...   .|. .....|.   | |    .  ||. .   .... |.
PP-VTVKEGETVTLTC-VS------------------------QIWWY---LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ
IGc2 AqueK457.AA IGc2 249-323 20 2e-06 28.47 SMART 1-56 (56) Show / Hide 
Range on Protein: 249-323
Range on HMM: 1-56/56
Sequence Identity: 20% (15 aa)

IYGTSVSIPCSVQDSAYEPGLEIYWTHNGANVSQSSHQSRAYETRSSNTVSELIFPAFSTSDNGEYKCHASNSND
. |.||...| .   .  |. .| |.. |  ..               . ..| .  .. .| |.| | |.|.. 
HEGQSVTLTCPA---TGNPDPNIHWYK-GQPLP---------------WNWTLTIKNVTPEDSGYYTCYARNPWG
IG AqueK457.AA IG 243-346 15 5e-06 27.21 SMART 1-58 (58) Show / Hide 
Range on Protein: 243-346
Range on HMM: 1-58/58
Sequence Identity: 15% (17 aa)

SIHTNFIYGTSVSIPCSVQDSAYEPGLEIYWTHNGANVSQSSHQSRAYETRSSNTVSELIFPAFSTSDN---GEYKCHASNSNDADERTTTIIGAPQKP-
.  .    | .|...| |.        .|.|.                          |..   . .|    |.| | |.             .  ..  
PP-VTVKEGETVTLTC-VS--------QIWWY--------------------------LTI-NVQPEDSQQHGTYYCQAT-------------HGQYWSI

NITTLTVS
. |||||.
QGTTLTVQ
V-set AqueK457.AA V-set 251-345 17 0.000711 15.19 Pfam 21-128 (128) Show / Hide 
Range on Protein: 251-345
Range on HMM: 21-128/128
Sequence Identity: 17% (21 aa)

GTSVSIPCSVQDSAYE--PGLEIYWTH-NGA---------------------NVSQSSHQSRAYETRSSNTVSELIFPAFSTSDNGEYKCHASNSNDADE
|.||..||...|.  .  . . |||     .                     ... .   ..   .  |..   |     . ||.| | | ..|.     
GQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWNC-----

RTTTIIGAPQKPNITTLTV
      .  .  . |.|||
------NEDYFGHGTRLTV
Kinase AqueK457.AA TK 583-854 19 3.8e-78 261.41 In-house 1-486 (486) Show / Hide 
Range on Protein: 583-854
Range on HMM: 1-486/486
Sequence Identity: 19% (97 aa)

LELTDILYDGSYT---VIYKAKATGI---------------------KDNKSIEVMAKCIKEEY-GDMDDYVS-------------ALVTEMEHLSQ-FE
..| . |  | .    ..||... |.                     |... ..|  |..||.   ....                ... ||. ...   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

PHPNIVGLIKVCTVG------------KPVYMIMEYMCHGD----LLGFLRATRGHPDMYTVFPGTKNVPSNLK--------------------------
 ||||| |. ||| |            .|....||||.|||    |. .||. |..   .   |.. . . .                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LKSRDLLRIISQIADGMNYLSGL------KIPHTALCARNILVGTSME-----------VKIYNIG---
                               |  ..|| .  |||.|| ||. .      .. |  |.|||.||| ..            .||   |   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

------AHNLDSNEVY------------------------------ESLVRWWAPEVFH---------DGNHSVLSDIWSFGVVMWEVVTVG-GTPYNDV
      |  ..|.. |                                 .|| |||..          .| ..  ||.|||||.|||..| | ...| ..
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

NL---------DDIYPQLMAG--------------LRLQRPAHCT--------------QPIYDIMTSCWENIPQHRPTFLEITDQL
.          .... .| .|              .|. .|.||.              . .||.|..||.  |..|||| .. .||
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK457.AA TK-Unique 583-854 30 1.4e-72 247.49 In-house 1-294 (294) Show / Hide 
Range on Protein: 583-854
Range on HMM: 1-294/294
Sequence Identity: 30% (91 aa)

LELTDILYDGSYTVIYKAKATGIK--DNKSIEVMAKCIKEEYGDMDDYVSALVTEMEHLSQFEPHPNIVGLIKVCTVGK-PVYMIMEYMCHGDLLGFLRA
||. |....|..  .......||.  ..| . |  |  |..  | |  ....  | .....  .||||| .. .||    |...||||.  |.|...|| 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTD--KQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRT

TR-GHPDMY------TVFPGTKNVPSNLKLKSRDLLRIISQIADGMNYLSG--LKIPHTALCARNILVGTSMEVKIYNIGAHN-------LDSN-EVYES
.| .. . .        |.  .  |..  ....||.... ||| ||.||..   || |  |||||.|..   ..|| . |          .... .  . 
CRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRI

LVRWWAPEVFH--DGNH-SVLSDIWSFGVVMWEVVTVGGTPYNDVNLDDIYPQLMAGLRLQRPAHC-TQPIYDIMTSCWENIPQHRPTFLEITDQL
 .|| |||..   .|.. .  ||.|||||.|||..| |..||...  .||  .. .| |...|.|| .. .| .| |||   |..||.| .|...|
PIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK457.AA TyrKc 583-854 29 7.3e-67 229.36 SMART 1-280 (280) Show / Hide 
Range on Protein: 583-854
Range on HMM: 1-280/280
Sequence Identity: 29% (91 aa)

LELTDILYDGSYTVIYKAKATGIKDNKSIEVMAKCIKEEYGDMDDYVSALVTEMEHLSQF-EPHPNIVGLIKVCTVG-------KPVYMIMEYMCHGDLL
..| ..|  | . ..||....       |.|  |..||.       . ..  |.. ....   ||||| |. ||| .       .|....||||.||||.
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

GFLRATRGHPDMYTVFPGTKNVPSNLKLKSRDLLRIISQIADGMNYLSGLKIPHTALCARNILVGTSMEVKIYNIG-AHNLDSN-------EVYES----
 .||..|..                  |. .||| .  |||.||.||.  .. |  | |||.|||    |||   | . ....        ..| .    
DYLRKHRPK------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHK

LVR------WWAPEVFHDGNHSVLSDIWSFGVVMWEVVTVGGTPYND-----VNLDDIYPQLMAGLRLQRPAH--------CTQPIYDIMTSCWENIPQH
  .      | |||.. .|  .  ||.|||||.|||. | |..|| .     .. .... ....| |. .|..        |.. .|.||..||.  |  
GGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPED

RPTFLEITDQL
|||| || ...
RPTFSEIHECF
Kinase AqueK457.AA UTK 639-854 30 8.6e-65 220.58 In-house 63-296 (296) Show / Hide 
Range on Protein: 639-854
Range on HMM: 63-296/296
Sequence Identity: 30% (75 aa)

LSQFEPHPNIVGLIKVCTVGKPVYMIMEYMCHGDLLGFLRATRGHPDMYTVFPGTKNVPSNLKLKSRDLLRIISQIADGMNYLSGLKIPHTALCARNILV
..||. |||...|. ||| ..| ....|||. |||. .||  |  |.           .  . |.....|   ..||.||.||.. .. |  |.|||.||
MKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPP-----------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLV

GTS-------MEVKIYNIG----AHNLD---------SNEVYESL------VRWWAPEVFHDG-NHSVLSDIWSFGVVMWEVVTVGGTPYNDVNLDDIYP
. .       | .||.. |    ....          . . | .       .|| |||.. ..  .. .||.||||||.||..| | .|| . . ...  
HMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWH

QLMAG--LRLQRPAHCTQPIYDIMTSCWENIPQHRPTFLEITDQL
|...|  .|. .|..|  |.|..|..||.  || ||.| ....|.
QVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK457.AA Tie 591-854 33 1.4e-51 154.91 In-house 1-267 (267) Show / Hide 
Range on Protein: 591-854
Range on HMM: 1-267/267
Sequence Identity: 33% (91 aa)

DGSYTVIYKAKATGIKDNKSIEVMAKCIKEEYGDMDDYVSALVTEMEHLSQFEPHPNIVGLIKVCTVGKPVYMIMEYMCHGDLLGFLRATR--GHPDMYT
.| .  . ||.    ||   .||  | .||   . |      . |.| . .   ||||. |.  |     .|. .||  .| || |||  |       . 
EGNFGQVMKAMIK--KDGLKMEVAIKMMKEYASEDDHR--DFMGELEVMCKVGHHPNIINLVGACEHRGYLYVAIEYAPYGNLLDFLRKSRVIETDPAFA

VFPGT-KNVPSNLKLKSRDLLRIISQIADGMNYLSGLKIPHTALCARNILVGTSMEVKIYNIGAHNLDSNEVYESL------VRWWAPEVFHDGNHSVLS
  ..|   |     | |. .|.  . .| ||.|||  .. |  | ||||||.  .  ||   |     ..|||         ||| | |          |
REHTTRFKVNVASTLSSQQILHFAADVARGMQYLSQKQCIHRDLAARNILVCENYVCKIADFGLSR--GDEVYVKKTMGRLPVRWMAIESLNYSVYTTKS

DIWSFGVVMWEVVTVGGTPYNDVNLDDIYPQLMAGLRLQRPAHCTQPIYDIMTSCWENIPQHRPTFLEITDQL
|.||.||..||.|..|||||  .   ..| .|  | |...|  |   .||.|  || . |  ||.| .|  ||
DVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYDLMRQCWRDRPYERPPFAQIAVQL
Kinase AqueK457.AA Abl 645-854 34 2.9e-46 152.07 In-house 54-252 (252) Show / Hide 
Range on Protein: 645-854
Range on HMM: 54-252/252
Sequence Identity: 34% (75 aa)

HPNIVGLIKVCTVGKPVYMIMEYMCHGDLLGFLRATRGHPDMYTVFPGTKNVPSNLKLKSRDLLRIISQIADGMNYLSGLKIPHTALCARNILVGTSMEV
|||.| |. |||   | |.| |.||.| || .|| .                 .  .|..  || . .||| ||.||   .  |  | ||| |||    |
HPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLREC-----------------DREELPAVVLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIV

KIYNIGAHNLDSNEVYESL------VRWWAPEVFHDGNHSVLSDIWSFGVVMWEVVTVGGTPYNDVNLDDIYPQLMAGLRLQRPAHCTQPIYDIMTSCWE
|.   |   .  ...|         ..| |||       |. ||.| |||..||. | | .||  ..| ..| .|  | |..||  | . .|..|  ||.
KVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQ

NIPQHRPTFLEITDQL
  .  ||.| ||  ..
WSHTDRPSFKEIHHAM
Kinase AqueK457.AA Musk 645-854 30 6.1e-46 149.66 In-house 61-282 (282) Show / Hide 
Range on Protein: 645-854
Range on HMM: 61-282/282
Sequence Identity: 30% (70 aa)

HPNIVGLIKVCTVGKPVYMIMEYMCHGDLLGFLRATRGHPDMYTVFPGTKNVPS---------NLKLKSRDLLRIISQIADGMNYLSGLKIPHTALCARN
||||| |  || ||.|  . .|||  |||  ||..   |    ..   | . ..          . ||  ..| .  ||| || |||  .  |  |  ||
HPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSCSPH----RTCSRTHQDRGMRAQVSSPGPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRN

ILVGTSMEVKIYNIG-AHNLDSNEVYESL------VRWWAPEVFHDGNHSVLSDIWSFGVVMWEVVTVGGTPYNDVNLDDIYPQLMAGLRLQRPAHCTQP
 |..  | |||   | ...  . . |         .|| .||   .   .. ||.|..||..||.   .  ||      ..      | .|  |  | | 
CLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESIWYNQFTYESDVWAYGVCLWEIFSYALQPYYGMTHEEVIYYIRQGNILSCPENCPQK

IYDIMTSCWENIPQHRPTFLEITDQL
.| .|  ||.  |  || | .| . .
VYQLMRRCWQKNPADRPFFCQIHHCI
Kinase AqueK457.AA Pkinase_Tyr 764-854 41 4e-39 133.14 Pfam 178-270 (270) Show / Hide 
Range on Protein: 764-854
Range on HMM: 178-270/270
Sequence Identity: 41% (39 aa)

VRWWAPEVFHDGNHSVLSDIWSFGVVMWEVVTVGGTP-YNDVNLDDIYPQL-MAGLRLQRPAHCTQPIYDIMTSCWENIPQHRPTFLEITDQL
..| |||....|  .. ||.|||||.|||..| |..| | ..   ..| ..   | |. .| .|...|||.|..||.  |..|||| ||  ||
IKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK457.AA Pkinase_Tyr 583-746 36 1.3e-38 131.35 Pfam 1-152 (270) Show / Hide 
Range on Protein: 583-746
Range on HMM: 1-152/270
Sequence Identity: 36% (61 aa)

LELTDILYDGSYTVIYKAKATGIKDNKSIEVMAKCIKEEYGDMDDY--VSALVTEMEHLSQFEPHPNIVGLIKVCT-VGKP--VYMIMEYMCHGDLLGFL
...   |  |.. ..||....| .||. |.|  |..||  | |..     ..  |.. ..|.  ||||| |. |||  |.|  .|..||||.||||| .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RATRGHPDMYTVFPGTKNVPSNLKLKSRDLLRIISQIADGMNYLSGLKIPHTALCARNILVGTSMEVKI
|. |               ... .|.  ||| .  |||.||.||.  .. |  |.|||.||. .. |||
RKHR---------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKI
Kinase AqueK457.AA CTKA 713-854 34 3.4e-36 119.02 In-house 139-290 (290) Show / Hide 
Range on Protein: 713-854
Range on HMM: 139-290/290
Sequence Identity: 34% (52 aa)

QIADGMNYLSGLKIPHTALCARNILVGTSMEVKIYNIGAHNLDSNE----VYESL----VRWWAPEVFHDGNHSVLSDIWSFGVVMWEVVTVGGTPYNDV
|||.|||||. . . |  | .||.|.|    .|| . |   . . |    .  |     ||| |||    | .|  ||.|.|||..||. . | .|.   
QIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHM

NLDDIYPQLMAG--LRLQRPAHCTQPIYDIMTSCWENIPQHRPTFLEITDQL
    .     ..   ||  |  | | .|  |. ||   |. ||||  .   |
SDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase AqueK457.AA FGFR 764-854 39 2.9e-33 110.71 In-house 202-293 (293) Show / Hide 
Range on Protein: 764-854
Range on HMM: 202-293/293
Sequence Identity: 39% (36 aa)

VRWWAPEVFHDGNHSVLSDIWSFGVVMWEVVTVGGTPYNDVN-LDDIYPQLMAGLRLQRPAHCTQPIYDIMTSCWENIPQHRPTFLEITDQL
. | |||   |    . ||.||.|| .||. | ||.||  .    ..|  |. | |. .|..|.| || .| .||   |. |||| .. ..|
IKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase AqueK457.AA Src 764-854 35 1e-29 98.09 In-house 164-255 (255) Show / Hide 
Range on Protein: 764-854
Range on HMM: 164-255/255
Sequence Identity: 35% (33 aa)

VRWWAPEVFHDGNHSVLSDIWSFGVVMWEVVTVGGTPYNDVNLDDIYPQLMAGLRLQRPAHCTQPIYD-IMTSCWENIPQHRPTFLEITDQL
..| ||| .. |. .. || ||||. ..|.|| | .||   .  .   |...| |. .|..| . .|. ||. ||.. |. ||||  . . |
IKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK457.AA InsR 764-856 41 1.5e-28 92.98 In-house 185-278 (278) Show / Hide 
Range on Protein: 764-856
Range on HMM: 185-278/278
Sequence Identity: 41% (39 aa)

VRWWAPEVFHDGNHSVLSDIWSFGVVMWEVVTVGGTPYNDVNLDDIYPQL-MAGLRLQRPAHCTQPIYDIMTSCWENIPQHRPTFLEITDQLQS
||| |||   ||  .  ||.||||||.||.|| |  ||     . .     |.|  |..|  | .  ...|  ||   |..|||||.| . |. 
VRWMAPESLKDGVFTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase AqueK457.AA Src 645-746 31 1e-22 73.96 In-house 53-138 (255) Show / Hide 
Range on Protein: 645-746
Range on HMM: 53-138/255
Sequence Identity: 31% (32 aa)

HPNIVGLIKVCTVGKPVYMIMEYMCHGDLLGFLRATRGHPDMYTVFPGTKNVPSNLKLKSRDLLRIISQIADGMNYLSGLKIPHTALCARNILVGTSMEV
|...| |  ||. ..|.| . |||.|| || .|..                 .   .|. ..|. .  |.|.||.||.  .. |  | |||.|||..  .
HEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK----------------DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVC

KI
|.
KV
Kinase AqueK457.AA FGFR 583-746 33 6.5e-21 67.96 In-house 1-177 (293) Show / Hide 
Range on Protein: 583-746
Range on HMM: 1-177/293
Sequence Identity: 33% (61 aa)

LELTDILYDGSYTVIYKAKATGIKDN---KSIEVMAKCIKEEYGDMDDYVSALVTEMEHLSQFEPHPNIVGLIKVCTVGKPVYMIMEYMCHGDLLGFLRA
| |  .|  | .  . .| | ||. .   | | |  | .|..  | |   | || ||| .     |.||. |. .|| . | | | ||  || |  ||||
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKD--LSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRA

TRGHPDMYTVFPGTK-------NVPSNL-------KLKSRDLLRIISQIADGMNYLSGLKIPHTALCARNILVGTSMEVKI
 |  |      . ..         |.          | ..|| ..  |.| ||.||   |. |  | |||.||.   . ||
RR--PPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKI
Kinase AqueK457.AA InsR 645-746 32 8.1e-16 49.52 In-house 63-160 (278) Show / Hide 
Range on Protein: 645-746
Range on HMM: 63-160/278
Sequence Identity: 32% (34 aa)

HPNIVGLIKVCTVGKPVYMIMEYMCHGDLLGFLRATRGHPDMY---TVFPGTKNVPSNLKLKSRDLLRIISQIADGMNYLSGLKIPHTALCARNILVGTS
. ..| |  ||. | | | .|| | .|||  .||. |  |..    .. .. . ||.  .     ..   ..|.||| ||  .|  |  | .|| .|  .
CHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRR--PEEEFNNPGCNRNQHVPCLDQ-----MHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHD

MEVKI
  |||
FTVKI
Kinase AqueK457.AA S_TKc 583-857 19 4e-14 30.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 583-857
Range on HMM: 1-231/231
Sequence Identity: 19% (55 aa)

LELTDILYDGSYTVIYKAKATGIKDNKSIEVMAKCIKEEYGDMDDYVSALVTEMEHLSQFEPHPNIVGLIKVCTVGKPVYMIMEYMCH--GDLLGFLRAT
 |. ...  |.. . ||.. ..       .|  |.||            .  |.. |..   ||||| |. |.   . .||.|||. .  |||. ...  
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR

RGHPDMYTVFPGTKNVPSNLKLKSRDLLRIISQIADGMNYLSGLKIPHTALCARNILVGTSMEVKI--YNIGAHNLDSNEVYESLV---RWWAPEVFHDG
..|.              . ..   .  ... ||.....|.  ..| |  |   |||. .  ..||    . ..         ...    . ||||.   
GRHG-------------LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---

NHSV-LSDIWSFGVVMWEVVTVGGTPYNDVNLDDIYPQLMAGLRLQRPAHCTQPIYDIMTSCWENIPQHRPTFLEITD------QLQSL
 ..   .|.||.|....| .. | .|.   ... .. ...           ...  |..  |..  |..|||  |.        . . .
GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK457.AA CTKA 635-681 51 2.7e-12 37.48 In-house 57-104 (290) Show / Hide 
Range on Protein: 635-681
Range on HMM: 57-104/290
Sequence Identity: 51% (25 aa)

EMEHLS--QFEPHPNIVGLIKVCTVGKPVYMIMEYMCHGDLLGFLRATR
|   ||  .|. |||...|. |||  || .||||.|  |||  .||| |
EAFVLSSEHFH-HPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCYLRACR
Kinase AqueK457.AA Pkinase 583-721 19 3.1e-11 40.83 Pfam 1-124 (293) Show / Hide 
Range on Protein: 583-721
Range on HMM: 1-124/293
Sequence Identity: 19% (28 aa)

LELTDILYDGSYTVIYKAKATGIKDNKSIEVMAKCIKEEYGDMDDYVSALV-TEMEHLSQFEPHPNIVGLIKVCTVGKPVYMIMEYMCHG----DLLGFL
...  ..  ||. . ||..  |  .    .|  |.|| .  ...  ....  .| . .  .  ||||| |. ... .. .||.|||. .|    ||  ..
YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

RATRGHPDMYTVFPGTKNVPSNLKL--KSRDLLRIISQIADGMNYL
..                  .. ..    ... ... ||. |..|.
ST-----------------WRHGCFYFSEWECKFYMYQILRGLEYC
Kinase AqueK457.AA Pkinase 765-854 18 8.8e-08 28.6 Pfam 176-293 (293) Show / Hide 
Range on Protein: 765-854
Range on HMM: 176-293/293
Sequence Identity: 18% (22 aa)

RWWAPEVFH-DGNHSVLSDIWSFGVVMWEVVTVGGTPYNDV------NLDDIYPQLMA-GLRLQRPAHCT-------------------QPIYDIMTSCW
.. ||||   .  ..  .|.||.|....|... | .|. .       . . .. . |   |. ..|  |.                   ..  |....|.
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

ENIPQHRPTFLEITDQ--L
.  |. |||. .|     .
CKDPKKRPTAEQILQHPWF