AqueK455

Species: A.queenslandica
Alias: AqueK455
External Links:
Annotation:

Classification

Group: TK
Family: TK-Unique

Sequence

Name Sequence Type Origin Length Description Download
AqueK455.AA Protein None 1532 None Fasta, JSON
AqueK455.kin_dom Protein Kinase Domain None 266 None Fasta, JSON

Protein domain

Protein domains of AqueK455.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
IGc2 AqueK455.AA IGc2 420-493 22 0.000765 11.73 SMART 1-56 (56) Show / Hide
Range on Protein: 420-493
Range on HMM: 1-56/56
Sequence Identity: 22% (17 aa)

DDGSILSLSCAVTDGDTLQPGQELVWTEGGIEIQGKSYNMTVQQTNTSSLLTIYNVTDGLQYGEYGCQCHNRHN
  |  ..| | .    |  |. .  |.  | ...            ... ||| |||   . |.| |.  |...
HEGQSVTLTCPA----TGNPDPNIHWYK-GQPLP------------WNWTLTIKNVT-PEDSGYYTCYARNPWG

Pkinase_Tyr AqueK455.AA Pkinase_Tyr 997-1259 42 2.5e-128 435.26 Pfam 1-270 (270) Show / Hide
Range on Protein: 997-1259
Range on HMM: 1-270/270
Sequence Identity: 42% (115 aa)

LSFEGELGSGAFGTVKKARVAGIKGDTNEKVVAVKMLKCLPSEED--MRDIITEFNILKHVGRHDNIVGLLGASE-HNGQ--LLVIVEYCSGGNLLQHLR
..|  .||.||||.|.|..  | ..| ..  |||||||   ..|.  ..| . | .|.|. |.|.||| |.|.   . ..  .....||. .|.|| .||
ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KKRQDSLDPLTTLKQIKMALQVSRGMAFLSTQKCVHRDLAARNILLDHEGTLKVADFGLARET-LYSIY-TKTSKGKIPFKWMSPESIFDKIYTTKSDVW
|.| .. .|||.   ..|..|...||..|. ..|.||||||||.|...... |..||||||     . | .|...||.| |||.||.|.....|||||||
KHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SFGVLLMEIITLGQTP-YPGKTVDEVIECL-RSKKTMTKPQSCPIKVYDIMRQCWQFDPKLRPSFHELITIL
|||||. ||.|.|..| ||| .  ||.| . ..   | .|. || ..||.|.|||..||. ||.| |.. .|
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

TyrKc AqueK455.AA TyrKc 997-1259 35 1.3e-124 421.24 SMART 1-280 (280) Show / Hide
Range on Protein: 997-1259
Range on HMM: 1-280/280
Sequence Identity: 35% (106 aa)

LSFEGELGSGAFGTVKKARVAGIKGDTNEKVVAVKMLKCLPSEEDMRDIITEFNILKHVG-RHDNIVGLLGASEHN-------GQLLVIVEYCSGGNLLQ
.... .||.||||.| |..            |||||||       ..|.. | .|....| .|.||| |.|.  .        ..|....||...|.|..
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

HLRKKRQDSLDPLTTLKQIKMALQVSRGMAFLSTQKCVHRDLAARNILLDHEGTLKVADFGLARETLYS--------IYTKTS--KGK--IPFKWMSPES
.|||.| .    |.. . .....|...||..|. ..|.||||||||.|.....| |..||||.|.             |.|..   ||  .| .||.||.
YLRKHRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

IFDKIYTTKSDVWSFGVLLMEIITLGQTPYPG-----KTVDEVIECLRSKKTMTKPQS--------CPIKVYDIMRQCWQFDPKLRPSFHELITIL
|.....|||||||||||.. || |.||.||||     .. .||||.... . | .|..        || ..|.||.|||..||. ||.| |.. ..
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase AqueK455.AA TK 997-1259 23 1.4e-109 368.69 In-house 1-486 (486) Show / Hide
Range on Protein: 997-1259
Range on HMM: 1-486/486
Sequence Identity: 23% (114 aa)

LSFEGELGSGAFG---TVKKARVAGIKGDTNEK--------------------VVAVKMLK--CLPSEEDMRD--------------IITEFNILKH-VG
. .. .||.|.||   .| |... |.... ...                     |||||||  .  |.|...|                 |  ...| .|
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHDNIVGLLGASEHN------------GQLLVIVEYCSGGN----LLQHLRKKRQDSLD-----------------------------------------
.|.||| |.|.. ..            . .....||...|.    |...|||.| .  .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------PLTTLKQIKMALQVSRGMAFLSTQKC------VHRDLAARNILLDHEGT-----------LKVADFGLAR
                              .||.  .. |..|...||..|. ..|      |||||||||.|......            |.|||||.|
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------ETLYS--IYTKTS------------------------KGKIPFKWMSPESIFDKI---------YTTKSDVWSFGVLLMEIITLGQTPYPG-K
         .||   |...|                        .||.|..||.||...|..         .||||||||||||. || |.||.||.|  
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TV---------DEVIECLRS--------------KKTMTKPQSCP--------------IKVYDIMRQCWQFDPKLRPSFHELITIL
.          .||.|.||.              .  | .|. ||                .||.|.|||..||. ||.| .|   |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK455.AA TK-Unique 997-1259 37 6.9e-101 341.47 In-house 1-294 (294) Show / Hide
Range on Protein: 997-1259
Range on HMM: 1-294/294
Sequence Identity: 37% (110 aa)

LSFEGELGSGAFGTVKKARVAGIKGDTNEK-VVAVKMLKCLPSEEDMRDIITEFNILKHVGRHDNIVGLLGASEHNG-QLLVIVEYCSGGNLLQHLRKKR
| .. ..|.||||.| .. | ||... ... .|||||||   ...| .|   |....|..|.| ||| .||..  .. . . | |||..|||. .||..|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

---------------------QDSLDPLTTLKQIKMALQVSRGMAFLST--QKCVHRDLAARNILLDHEGTLKVADFGLAR--ETLYSIYTKTSKGKIPF
                     .....|..    .  | |. .||..|.   .|.|||||.|||.|| . ...|..|||.||  .|   . ...|.|.|| 
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWMSPESIF--DKIY-TTKSDVWSFGVLLMEIITLGQTPYPGKTVDEVIECLRSKKTMTKPQSC-PIKVYDIMRQCWQFDPKLRPSFHELITIL
.||.|||.   ...| ||||||||||||. || |||..||||   ....||.|  ..| .|..| .  .| .|..||| .|. |||| ... .|
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL

Kinase AqueK455.AA FGFR 997-1259 41 1.7e-100 340.16 In-house 1-293 (293) Show / Hide
Range on Protein: 997-1259
Range on HMM: 1-293/293
Sequence Identity: 41% (122 aa)

LSFEGELGSGAFGTVKKARVAGIKGD--TNEKVVAVKMLKCLPSEEDMRDIITEFNILKHVGRHDNIVGLLGASEHNGQLLVIVEYCSGGNLLQHLRKKR
|.    || |.|| | .| . ||. |   .|  |||||||   ...|. | . |  ..| .|.| ||. |||.   .| | ||||||. |||   ||..|
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRARR

-------QDSL-----DPLTTLKQ--------------IKMALQVSRGMAFLSTQKCVHRDLAARNILLDHEGTLKVADFGLARETLYS-IYTKTSKGKI
       .||       |... .|              ...| || ||| .|  .||.||||||||.|   .  .|..||||||   .   | ||. |  
PPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNGRL

PFKWMSPESIFDKIYTTKSDVWSFGVLLMEIITLGQTPYPGKT-VDEVIECLRSKKTMTKPQSCPIKVYDIMRQCWQFDPKLRPSFHELITIL
| ||| ||. ||..||..|||||.|||| || |.|..|||.   | |  . |.. . | ||. |.  .| .|.||| | |. ||.| .|.  |
PIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL

Kinase AqueK455.AA UTK 997-1259 32 4.6e-88 298.86 In-house 1-296 (296) Show / Hide
Range on Protein: 997-1259
Range on HMM: 1-296/296
Sequence Identity: 32% (95 aa)

LSFEGELGSGAFGTVKKARVAGIKGDTNEKVVAVKMLK-CLPSEEDMR---DIITEFN---ILKHVGRHDNIVGLLGASEHNGQLLVIVEYCSGGNLLQH
. .  .||.||||.| |||.  ...   | .|||| ..   ... ...   |.. | .   ..|..  | |...|.|     .......||...|.|.. 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRKKRQ---DSLDPLTTLKQIKMALQVSRGMAFLSTQKCVHRDLAARNILLDHEG-------TLKVADFG---LARETL---------YS-IYTKTSKGK
||. |.   .  . ||  ....||....|||..|.....|||||||||.|... .       . |.||||   ..|.           .|  |.... ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

IPFKWMSPESIFDK-IYTTKSDVWSFGVLLMEIITLGQTPYPGKTVDEVIECLRSK--KTMTKPQSCPIKVYDIMRQCWQFDPKLRPSFHELITIL
.|..||.||.. .   .|||||||||||...|| | |..|||| . ..|.. .. .    | .|..||  ||..|..||. ||  ||.|..|   .
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM

Kinase AqueK455.AA Fer 997-1260 31 2.4e-80 273.23 In-house 1-283 (283) Show / Hide
Range on Protein: 997-1260
Range on HMM: 1-283/283
Sequence Identity: 31% (91 aa)

LSFEGELGSGAFGTVKKAR-VAGIKGDTNEKV--VAVKMLKC---LPSEEDMRDIITEFNILKHVGRHDNIVGLLGASEHNGQLLVIVEYCSGGNLLQHL
  ..  ||.||||.|.|.| .  .| ...  |  ||||. ||   ....| ....  | .|..    |.|.| . | . .   .... |.|.||.|. .|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

RKKRQDSLDPLTTLKQIKMALQVSRGMAFLSTQKCVHRDLAARNILLDHEGTLK---VADFGLARETLYSIYTKTSK---GKIPFKWMSPESIFDKIYTT
.|. ..    ... . |.|..|...||..|  ..|.|||.||||.|...... |   ..|||..|..   .|... |    |.| .|..||.. ..||..
KKNKNK---TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSP

KSDVWSFGVLLMEIITLGQTPYPG--------KTVDEVIEC-LRSKKTMTKPQSCPIKVYDIMR-QCWQFDPKLRPSFHELITILE
|.|||||||.. || | |..||||         . .. ..   .. . |. |...|  .. ||  |||| ||. ||.. |.. .|.
KTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK

Kinase AqueK455.AA Src 997-1259 39 7e-80 271.08 In-house 1-255 (255) Show / Hide
Range on Protein: 997-1259
Range on HMM: 1-255/255
Sequence Identity: 39% (105 aa)

LSFEGELGSGAFGTVKKARVAG-IKGDTNEKVVAVKMLKCLPSEEDMRDIITEFNILKHVGRHDNIVGLLGASEHNGQLLVIVEYCSGGNLLQHLRKKRQ
. .. .||.| || | ..   | .|       |||| ||  |   .  .   | .|.| . ||...| |.         . . || | |.||. |.|  .
IKLCRKLGQGQFGEVWMGYWNGNTK-------VAVKTLK--PGTMSPEAFLQEAQIMKKL-RHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK--D

DSLDPLTTLKQIKMALQVSRGMAFLSTQKCVHRDLAARNILLDHEGTLKVADFGLARETL--YSIYTKTSKGKIPFKWMSPESIFDKIYTTKSDVWSFGV
.    |   ..| || ||..|||.|. .. .||||||||.| ...   ||||||||| .     .|.  .  |.| ||. || |    .|.||||||||.
GEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGI

LLMEIITLGQTPYPGKTVDEVIECLRSKKTMTKPQSCPIKVYD-IMRQCWQFDPKLRPSFHELITIL
||.||.| |..|||| |  ||....     | .|. || ..|. ||.|||. ||. || |  |   |
LLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL

Kinase AqueK455.AA RTKB 997-1259 37 2.2e-79 267.24 In-house 1-264 (264) Show / Hide
Range on Protein: 997-1259
Range on HMM: 1-264/264
Sequence Identity: 37% (101 aa)

LSFEGELGSGAFGTVKKARVAGIKGDTNEKVVAVKMLKCLPSEEDMRDIITEFNILKHVGRHDNIVGLLGASEHNGQLLVIVEYCSGGNLLQHLRKKRQD
..   .||.|||| | .| |.  ..   |. .|.| ||   |.|.  |. .|  ..| .| | |..|..|   .   ... ||.|  |||   ||. |. 
VWLGEKLGNGAFGEVFQAWVR-NRHMNTEQSCAAKVLKPGASYEERQDFCSEMTVMKELGWHPNVIGIIGHCLQDEPYILLVELCELGNLRDYLRMCRAS

SLDPL-TTLKQ-IKMALQVSRGMAFLSTQKCVHRDLAARNILLDHEGTLKVADFGLARETLYSIYTKTSKGKIPFKWMSPESIFDKIYTTKS-DVWSFGV
. .|.    .| .. ..|. .|||||. .. .||||.|||.|.| . . |..|||.|||     |..|   . | ||| |||. ..|||||| |||||||
QHNPQSLKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREIDHECYETTCT-RLPIKWMAPESWAHRIYTTKSGDVWSFGV

LLMEIITLGQTPYPGKTVDEVIECLRSKKTMTKPQSCPIKVYDIMRQCWQFDPKLRPSFHELITIL
   || .|| |||.   . .. . |.|   . ||.. | ....||..|||...  ||.| ||.  .
TMWEIFSLGGTPYQQYRNGDIFYWLESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF

Kinase AqueK455.AA VEGFR 1097-1259 49 2.5e-71 243.26 In-house 166-332 (332) Show / Hide
Range on Protein: 1097-1259
Range on HMM: 166-332/332
Sequence Identity: 49% (83 aa)

SLDPLTTLKQIKMALQVSRGMAFLSTQKCVHRDLAARNILLDHEGTLKVADFGLARETLYSI---YTKTSKGKIPFKWMSPESIFDKIYTTKSDVWSFGV
..||||.   |  ..|| ||| ||. .||.|||||||||||.   ..|  ||||||  .|.     .|...|. | |||.|||||||.|||.|||||.||
WKDPLTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQGRLPIKWMAPESIFDKVYTTYSDVWSYGV

LLMEIITLGQTPYPGKTVD-EVIECLRSKKTMTKPQSCPIKVYDIMRQCWQFDPKLRPSFHELITIL
.| || .||  ||||  .| | .  |..   | .|  |.. .|.|| .||  .|. ||.| ||  .|
FLWEIFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL

Kinase AqueK455.AA PDGFR 1112-1259 50 4.8e-61 194.59 In-house 209-358 (358) Show / Hide
Range on Protein: 1112-1259
Range on HMM: 209-358/358
Sequence Identity: 50% (77 aa)

QVSRGMAFLSTQKCVHRDLAARNILLDHEGTLKVADFGLARETLY-SIYTKTSKGKI--PFKWMSPESIFDKIYTTKSDVWSFGVLLMEIITLGQTPYPG
|| .||.||    ||||||||||.|| |    |. ||||||  .  | |   .||    | ||| |||||| .|||.|||||.|.|| || .|| .||||
QVAKGMEFLASKNCVHRDLAARNVLLCHGKVVKICDFGLARDIMNDSNY--VVKGNARLPVKWMAPESIFDCVYTTQSDVWSYGILLWEIFSLGGNPYPG

KTVDEVI-ECLRSKKTMTKPQSCPIKVYDIMRQCWQFDPKLRPSFHELITIL
  ||.      ..   | .|.  |  .|.||..|| |||. ||.| .|  .|
MPVDSKFYKMIKEGYRMAQPFHAPEEIYEIMQKCWDFDPEKRPTFQQLCQFL

Kinase AqueK455.AA S_TKc 997-1263 26 2.7e-58 200.91 SMART 1-231 (231) Show / Hide
Range on Protein: 997-1263
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)

LSFEGELGSGAFGTVKKARVAGIKGDTNEKVVAVKMLKCLPSEEDMRDIITEFNILKHVGRHDNIVGLLGASEHNGQLLVIVEYCSG--GNLLQHLRKKR
  .  ..|.||||.|.|.|  .       ..||.|..|        ..|. | .|||.  .|.||| |... .. . | .. |||.|  |.|.....|..
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

QDSLD-PLTTLKQIKMALQVSRGMAFLSTQKCVHRDLAARNILLDHEGTLKVADFGLARETLYSIYTKTSKGKIPFKWMSPESIFDKIYTT-KSDVWSFG
   |. |..     ... |. ......  .. .||||   |||||.  ..|..||||||.         .       .|.|| .    |.. |.|.||.|
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VLLMEIITLGQTPYPGKTVDEVIECLRSKKTMTKPQSCPIKVYDIMRQCWQFDPKLRPSFHELIT-----ILEQFL
..| | .. |..|.|  ....... ..           .  . |..|.|.|.||. ||.  |. .      . ...
CILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK455.AA Ret 1112-1261 47 1.1e-57 195.54 In-house 143-293 (293) Show / Hide
Range on Protein: 1112-1261
Range on HMM: 143-293/293
Sequence Identity: 47% (72 aa)

QVSRGMAFLSTQKCVHRDLAARNILLDHEGTLKVADFGLARETLY--SIYTKTSKGKIPFKWMSPESIFDKIYTTKSDVWSFGVLLMEIITLGQTPYPGK
|...||..||  | |||||||||.|.     .|. |||| |   |    | | ||..|| ||| .|| .| .|||||||||||||. ||.|.|  |||| 
QICKGMHYLSEMKLVHRDLAARNVLVAEGRICKISDFGLTRD-VYEDDSYVKRSKDRIPVKWMAIESLYDHVYTTKSDVWSFGVLCWEIVTMGANPYPGI

TVDEVIECLRSKKTMTKPQSCPIKVYDIMRQCWQFDPKLRPSFHELITILEQ
. .   . |.    |  |  |   .| ||||||   |  ||.|  .   .|.
PPERLWQLLKTGYRMDRPENCSEEMYRIMRQCWKQEPDKRPVFKFISKDFEK

Kinase AqueK455.AA Pkinase 997-1255 24 1.2e-49 176.1 Pfam 1-287 (293) Show / Hide
Range on Protein: 997-1255
Range on HMM: 1-287/293
Sequence Identity: 24% (72 aa)

LSFEGELGSGAFGTVKKARVAGIKGDTNEKVVAVKMLKCLPSEEDMRDIIT---EFNILKHVGRHDNIVGLLGASEHNGQLLVIVEYCSGG----NLLQH
. ... .|||.||.|.|..  |        .|||| .|    ..... . .   |  |.|.. .|.||| |... | .. . .. ||| ||     |  .
YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

LRKKRQDSLDPLTTLKQIKMALQVSRGMAFLSTQKCVHRDLAARNILLDHEGTL----KVADFGLAR--ETLYSIYTKTSKGKIPFKWMSPESIF-DKIY
.. .|. ..  ..    .....|. ||....  ....||||   |||.|..|..    |..|||||.  .  |  .. ..       .|.|| |  .. |
ISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYY

TTKSDVWSFGVLLMEIITLGQTPYPGK----TVDEVIECLRSKKTMTKPQSCP-----------------------IKVYDIMRQCWQFDPKLRPSFHEL
..|.|.||.|..| | .. |..|.||.    . .. ..... ..    . ..|                           |... |...||| ||.....
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI





Kinase AqueK455.AA VEGFR 997-1095 42 1.2e-29 104.76 In-house 1-102 (332) Show / Hide
Range on Protein: 997-1095
Range on HMM: 1-102/332
Sequence Identity: 42% (43 aa)

LSFEGELGSGAFGTVKKARVAGIKGDTNEKVVAVKMLKCLPSEEDMRDIITEFNILKHVGRHDNIVGLLGASEH---NGQLLVIVEYCSGGNLLQHLRKK
|   . || |||| | .|   ||..  . ..|||||||  .  .  |   .|  .|.|.| | | | .||.      .| |.||||||  |||.  || |
LKLGKMLGRGAFGQVHEASAFGIRKMETCTTVAVKMLKEGATASEHRALMSELKMLIHIGHHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRTK

RQ
|.
RM

Kinase AqueK455.AA Ret 997-1094 37 3.3e-21 69.13 In-house 1-100 (293) Show / Hide
Range on Protein: 997-1094
Range on HMM: 1-100/293
Sequence Identity: 37% (38 aa)

LSFEGELGSGAFGTVKKARVAGIKGDTNEKVVAVKMLKCL-PSEEDMRDIITEFNILKHVGRHDNIVGLLGASEHNG--QLLVIVEYCSGGNLLQHLRKK
| .. .|| | || | ||    |.| .    |||||||    .    .|  .||..|| |  | ... |.||    .   ...|||||  | |   ||  
LQLDDTLGEGHFGQVVKAQAFHIRGHPGYTTVAVKMLKRNTANSSEYHDLLSEFQLLKQV-NHPHVIKLYGACIQDDPFPTCLIVEYCKYGCLREFLRLS

R
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R

Kinase AqueK455.AA PDGFR 997-1094 43 2.5e-20 61.61 In-house 1-98 (358) Show / Hide
Range on Protein: 997-1094
Range on HMM: 1-98/358
Sequence Identity: 43% (43 aa)

LSFEGELGSGAFGTVKKARVAGIKGDTNEKVVAVKMLKCLPSEEDMRDIITEFNILKHVGRHDNIVGLLGASEHNGQLLVIVEYCSGGNLLQHLRKKR
|.|   ||||||| |  |   |.        |||||||             |  |. | | |.||| ||||  | |  ..| |||  | ||  |..||
LQFGKTLGSGAFGKVVEATAYGLSKSQAVMKVAVKMLKPTAHSSEKEALMSELKIMSHLGQHMNIVNLLGACTHGGPIYIITEYCCYGDLLNYLHRKR