Gene AqueK453 (A.queenslandica)

AqueK453

Species: A.queenslandica
Alias: AqueK453
External Links:
Annotation:

Classification

Group: TK
Family: TK-Unique

Sequence

Name Sequence Type Origin Length Description Download
AqueK453.AA Protein None 949 None Fasta, JSON
AqueK453.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of AqueK453.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 AqueK453.AA SH2 567-644 31 6.6e-12 36.79 Pfam 1-81 (81) Show / Hide 
Range on Protein: 567-644
Range on HMM: 1-81/81
Sequence Identity: 31% (26 aa)

WYYKNIDEQDAEKLLTSHSTFSAGAYLIRRAKEQTL-NY-LSVLGNN---QVYHYPIYSGKNYTVYLSKKAQFPTLESLIKNY
||...|  |.||.|| . ..   |..|.|     |   | |||. ..   .|.|| | . .| ..|.. . .|..|  |.  |
WYHGKISRQEAERLLMN-PGNPDGTFLVRESES-TPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK453.AA SH2 565-650 26 1.2e-11 45.91 SMART 1-87 (87) Show / Hide 
Range on Protein: 565-650
Range on HMM: 1-87/87
Sequence Identity: 26% (24 aa)

KQWYYKNIDEQDAEKLLTSHSTFSAGAYLIRRAKE-QTLNYLSVLGNNQVYHYPIYSGKNYTVYLSK--KAQFPTLESLIKNYSKPSAE
 .||. ||. ..||.|| ..     |..|.|          |||  ...|.|| | . ..  .|.    . .||.|  |.  |....  
QPWYHGNISREEAEQLLKNP-GMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK453.AA TK-Unique 675-933 26 6.8e-57 194.7 In-house 1-294 (294) Show / Hide 
Range on Protein: 675-933
Range on HMM: 1-294/294
Sequence Identity: 26% (82 aa)

VSLQEFIHEGAHTQVFTGVFNR-------HQAVYAKVQKEGSSLS-VYNFLSEAAVMRSLQ-HNNIHQFISVTLLGTEQLCILHEPVYQLNLKECME---
. ... |.|||  ||..| . .       .. |. |  |.....  ...||.|...|..|  | || |.. ..   .|. .|. |.... ||  .     
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-------------------RMKKSSQTIADHTIFSYALQIARGMSYLES--HHCIFRNLACKNIVLVRGAQYRHILKLSNFSRACFSPSGT---------
                   ..|..  .|  .. ...| |||.||.||.|  .... |.|. .|. | .    ....|...| .|      .         
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE----DKVCKICDFGMA------RDVYTNGVYS

MTCRPFNILLRWTAPELLF--AGVC-SSKSDVWSYGITLWEILTYGSKPYGEHSSENVKEMVRQGHRIQLDGLALPKNVHRLISECWHQKPEERPSFKNL
|.|. . | .|| ||| |    |.. ..||||||.|...|||.|.|. ||.. ..... |..|.|.| ..     .. .. |...||. .|||||||  .
MMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQI

QERL
  ||
KHRL
Kinase AqueK453.AA TK 675-933 16 4.2e-56 186.22 In-house 1-486 (486) Show / Hide 
Range on Protein: 675-933
Range on HMM: 1-486/486
Sequence Identity: 16% (82 aa)

VSLQEFIHEGAHT---QVFTGVFNRH--------------------------QAVYAKVQKEG--SSLS-VYN--------------FLSEAAVMRS--L
. | . . ||.     .|. |  ...                          . |  |. |||  .|                    ...|...|..  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHNNIHQFISVTLLGT-----------EQLCILHEPVYQLN----LKECMERMKKSSQT-----------------------------------------
.| || ... | . |            | ..|. | .   .    |..   . ..  |.                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------IADHTIFSYALQIARGMSYLESH------HCIFRNLACKNIVLVRGAQ-------YRHILKLSNFS---
                               .  |.   ...|||.||.||.|.      ... |.||. |. . .. .       .  . |.. |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----RACFSPSGTMTCRPF--------------------------NILLRWTAPELLFAGV---------CSSKSDVWSYGITLWEILTYG-SKPYGEH
     .|   .|..  .|                             . .||.||| |. .|         ...||||||.|...|||.|||   .||..
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SS---------ENVKEMVRQGHR-------IQLDGLALP--------------------KNVHRLISECWHQKPEERPSFKNLQERL
|.         . | |..|.|.|        . ... .|                    . ...|. .||| .||.||.|. |.|.|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK453.AA TyrKc 675-933 27 4.2e-54 186.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 675-933
Range on HMM: 1-280/280
Sequence Identity: 27% (81 aa)

VSLQEFIHEGAHTQVFTGVFNRHQAVYAKVQKEGSSLSVYNFLSEAAVMRSL--QHNNIHQFISVTLLGT------EQLCILHEPVYQLNLKECMERMKK
..| . . |||  .|. |. .  . |  |. ||..   .  |..|| .|..|  .| || ... | . .       |.|.|. | .   .||.   . ..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

SSQTIADHTIFSYALQIARGMSYLESHHCIFRNLACKNIVLVRGAQYRHILKLSNFSRACFSPSG--------TMT-----CRPFNILLRWTAPELLFAG
    .   .  |...|||.||.||.|..|| | ||. |. . ..     . | | |  . .  ..        . .     .. . . .||.||| .. |
K---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

VCSSKSDVWSYGITLWEILTYGSKPYGE-----HSSENVKEMVRQGHRIQLDGLA-------LPKNVHRLISECWHQKPEERPSFKNLQERL
....||||||.|...|||.||| .|| .      | . | | |.||.|      .        |. .......||| .||.||.|... |..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK453.AA Abl 675-933 31 2.6e-42 138.63 In-house 1-252 (252) Show / Hide 
Range on Protein: 675-933
Range on HMM: 1-252/252
Sequence Identity: 31% (81 aa)

VSLQEFIHEGAHTQVFTGVFNRHQAVYAKVQKEGSSLSVYNFLSEAAVMRSLQHNNIHQFISVTLLGTEQLCILHEPVYQLNLKECMERMKKSSQTIADH
..... .  |   .|. ||. ||. . |       .. | .|| |||.|. ..| |. | . |         |. | . . || . . . ..  ...   
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPP-FYIITEFMCYGNLLDYLRECDR--EELPAV

TIFSYALQIARGMSYLESHHCIFRNLACKNIVLVRGAQYRHILKLSNFSRACFSPSGTMTCRP-FNILLRWTAPELLFAGVCSSKSDVWSYGITLWEILT
..   | ||| ||||||..| | | || .| ..       ||.|.  |  | .    | | .      ..||||| |     ||||||| .|. |||| |
VLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGE----HHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIAT

YGSKPYGEHSSENVKEMVRQGHRIQLDGLALPKNVHRLISECWHQKPEERPSFKNLQERL
||  ||     ..| . . .|.|..      |..| .|. .||. .. .|||||.. ...
YGMSPYPGIDLSHVYHKLEKGYRME-RPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK453.AA Pkinase_Tyr 843-933 39 3.5e-39 133.31 Pfam 179-270 (270) Show / Hide 
Range on Protein: 843-933
Range on HMM: 179-270/270
Sequence Identity: 39% (38 aa)

RWTAPELLFAGVCSSKSDVWSYGITLWEILTYGSKP-YGEHSSENVKEMV-RQGHRIQLDGLALPK----NVHRLISECWHQKPEERPSFKNLQERL
.|.||| .. |....||||||.|...|||.||| .| | . | | |.|.. ..|.|     .. |.     ...|. .|||..||.||.|. ..|.|
KWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR-----MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK453.AA Src-Echino1 675-933 29 2.3e-37 126.96 In-house 1-252 (252) Show / Hide 
Range on Protein: 675-933
Range on HMM: 1-252/252
Sequence Identity: 29% (77 aa)

VSLQEFIHEGAHTQVFTGVFNRHQAVYAKVQKEGSSLSVYNFLSEAAVMRSLQHNNIHQFISVTLLGTEQLCILHEPVYQLNLKECMERMKKSSQTIADH
. ... | .|  . |. ||.|    |  |  ||.. .|  .|| || ||. ..|..| |.  |     | . |. | . . ||.. . | |  .. .   
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKT-MSPADFLAEANVMKKCRHEGIVQIYAV-CSDKEPIYIVTELMSNGNLQDYLKRGK--CKHVKMT

TIFSYALQIARGMSYLESHHCIFRNLACKNIVLVRGAQYRHILKLSNFSRACFSPSGTMTCRPFNIL-LRWTAPELLFAGVCSSKSDVWSYGITLWEILT
|.     .|| || ||.|   . |.|| .|... .|     . |. .| .| .        .    | ..|||||    |    ||||||.|| . |..|
TLIDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGN----VCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVT

YGSKPYGEHSSENVKEMVRQGHRIQLDGLALPKNVHRL-ISECWHQKPEERPSFKNLQERL
.|  || .    .| . | .|.|.       |  .. . .  |||. |  || |. | . .
FGRYPYPGMMNREVLDQVDRGYRMPKM-HHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK453.AA Frk 675-937 29 1.1e-35 120.89 In-house 1-260 (260) Show / Hide 
Range on Protein: 675-937
Range on HMM: 1-260/260
Sequence Identity: 29% (79 aa)

VSLQEFIHEGAHTQVFTGVFNRHQAVYAKVQKEGSSLSVYNFLSEAAVMRSLQHNNIHQFISVTLLGTEQLCILHEPVYQLNLKECMERMKKSSQTIADH
. |   .  |   .|. | .|    |  |  | | ..   .|| || .|..|.|  . |   |  .  | . |. | . .  |.| .  ...  . .  .
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPG-TMDPNDFLREAQIMKKLRHPKLIQLYAVCTV-EEPIYIITELMRHGSLQEYLQAINDKGRQCQMQ

TIFSYALQIARGMSYLESHHCIFRNLACKNIVLVRGAQYRHILKLSNFSRAC-FSPSGT---MTCRPFNILLRWTAPELLFAGVCSSKSDVWSYGITLWE
..   | |.| || ||||.  | | || .|...  .     |.|.  |  |  .         .     . ..|||||       . ||||||.|| | |
QLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHN----ICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTE

ILTYGSKPYGEHSSENVKEMVRQGHRIQLDGLALPKNVHRLISECWHQKPEERPSFKNLQERLKVIQ
|.|||  ||      .| .|| .| |.       |...  .. ||||..|..|| |  || .|.   
IITYGRMPYPGMTNAEVLQMVDHGYRMPQPP-NCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK453.AA SrcB 675-934 30 8.7e-35 115.03 In-house 1-251 (251) Show / Hide 
Range on Protein: 675-934
Range on HMM: 1-251/251
Sequence Identity: 30% (80 aa)

VSLQEFIHEGAHTQVFTGVFNRHQAVYAKVQKEGSSLSVYNFLSEAAVMRSLQHNNIHQFISVTLLGTEQLCILHEPVYQLNLKECMERMKKSSQTIADH
. | . .  |    |. | .|.|  |  |  |.| ..|.  || || ||..|||. . .   |     | . |. | . .  | . .   . | ...   
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQG-TMSPEAFLAEANVMKTLQHDRLVRLYAV--VTKEPIYIITEYMAKGCLLDFLKTDEGSKLSLP--

TIFSYALQIARGMSYLESHHCIFRNLACKNIVLVRGAQYRHILKLSNFSRACFSPSGTMTCRP-FNILLRWTAPELLFAGVCSSKSDVWSYGITLWEILT
 .  .. ||| || |.| .  | | |   ||.         . |.  |  |    .   | |      ..||||| .  |.   ||||||.|| | || |
KLIDMSAQIAEGMAYIERMNYIHRDLRAANILVSETL----CCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVT

YGSKPYGEHSSENVKEMVRQGHRIQLDGLALPKNVHRLISECWHQKPEERPSFKNLQERLK
||  ||   .  .| . . .| |.       |. . ... .||...||||| |  ||  | 
YGRIPYPGMTNPEVIRNLERGYRMPRPD-NCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK453.AA UTK 842-933 40 7.7e-31 102.73 In-house 203-296 (296) Show / Hide 
Range on Protein: 842-933
Range on HMM: 203-296/296
Sequence Identity: 40% (38 aa)

LRWTAPELLFAG-VCSSKSDVWSYGITLWEILTYGSKPYGEHSSENVKEMVRQGHRIQLDG-LALPKNVHRLISECWHQKPEERPSFKNLQERL
.||.||| |  .   ..||||||.|...|||.|.|..||...| ..| . |. | | ..    . | .| ||  .|||. |.|||.|. | ...
IRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK453.AA Src 843-933 40 6.8e-30 98.72 In-house 165-255 (255) Show / Hide 
Range on Protein: 843-933
Range on HMM: 165-255/255
Sequence Identity: 40% (38 aa)

RWTAPELLFAGVCSSKSDVWSYGITLWEILTYGSKPYGEHSSENVKEMVRQGHRI-QLDGLALPKNVHR-LISECWHQKPEERPSFKNLQERL
.||||| .  |. . ||||||.|| |.|| |||  ||   . . | ..| .| |  . ..   |....  .. .|||..||.|| |. ||. |
KWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN--CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK453.AA Fer 843-934 33 2.6e-27 90.12 In-house 183-283 (283) Show / Hide 
Range on Protein: 843-934
Range on HMM: 183-283/283
Sequence Identity: 33% (35 aa)

RWTAPELLFAGVCSSKSDVWSYGITLWEILTYGSKPYGE--HSSE----NV-----KEMVRQGHRIQLDGLALPKNVHRLIS-ECWHQKPEERPSFKNLQ
||.||| .  |..|.|.||||.|...||| | | .||..  |  .    ||     |  .. |.. ..  .  |. . ...   ||...||.||..| ..
RWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPH--GMKMTNVKKQARKWIIKKGYMMPM-PNHMPPEIMQIMMKQCWQKDPEDRPTMKEIC

ERLK
..||
QKLK
Kinase AqueK453.AA FGFR 844-933 42 1.4e-26 87.54 In-house 204-293 (293) Show / Hide 
Range on Protein: 844-933
Range on HMM: 204-293/293
Sequence Identity: 42% (39 aa)

WTAPELLFAGVCSSKSDVWSYGITLWEILTYGSKPYGEHS-SENVKEMVRQGHRIQLDGLALPKNVHRLISECWHQKPEERPSFKNLQERL
| ||| ||  |  ..|||||||. ||||.|||  ||      |   .  . |||.    .  ....  .. .||| ||..||.|| | | |
WMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNC-SQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase AqueK453.AA Pkinase_Tyr 675-807 27 4.7e-15 51.62 Pfam 1-144 (270) Show / Hide 
Range on Protein: 675-807
Range on HMM: 1-144/270
Sequence Identity: 27% (39 aa)

VSLQEFIHEGAHTQVFTGVFN-----RHQAVYAKVQKEGSSLS---VYNFLSEAAVMRSL-QHNNIHQFISVTLLGTEQ--LCILHEPVYQLNLKECMER
... . . |||  .|. |. .      .. |  |. |||.. .      |..||..|..| .| || ... | .   |.  ..|  | .   .|..   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

MKKSSQTIADHTIFSYALQIARGMSYLESHHCIFRNLACKNIVL
 . . | .  ... ....|||.||.||||..|| | ||..|. .
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLV
Kinase AqueK453.AA S_TKc 675-936 18 8.1e-15 40.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 675-936
Range on HMM: 1-231/231
Sequence Identity: 18% (52 aa)

VSLQEFIHEGAHTQVFTGVFNR-HQAVYAKVQKEGSSLSVYNFLSEAAVMRSLQHNNIHQFISVTLLGTEQLCILHEPVYQ--LNLKECMERMKK--SSQ
  . . | .||  .|. .. .. .. |  |. |        ....| ..... .| || ... |     . |..  | . .   .|.. ......    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

TIADHTIFSYALQIARGMSYLESHHCIFRNLACKNIVLVRGAQYRHILKLSNFSRACFSPSGTMTCRPFNILLRWTAPELLFAGVCSS-KSDVWSYGITL
 .   .. .|. ||.... |. ||. | | |   || | .       .|.. |  |..        . |   . . |||.|     .  |.|.|| |..|
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

WEILTYGSKPYGEHSSENVKEMVRQGHRIQLDGLALPKNVHRLISECWHQKPEERPSFKNLQE------RLKVI
.| |. |  |.      ....| ..           .. .  .|. |..  ||.||.   . .          .
YEMLC-GYPPFP-----QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK453.AA UTK 675-807 23 3.5e-13 41.47 In-house 1-151 (296) Show / Hide 
Range on Protein: 675-807
Range on HMM: 1-151/296
Sequence Identity: 23% (36 aa)

VSLQEFIHEGAHTQVFTGVFNR--------HQAVYAKV-----QKEGSSLSVY-NFLSEAA---VMRSLQ-HNNIHQFISVTLLGTEQLCILHEPVYQLN
| | . . .||  .|. . |..        ..|| . .     |.|  .   |  |. ||.   .|  .. | |. ... | . .   ..|. |   . .
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEP---YPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGD

LKECMERMKKS---SQTIAD-HTIFSYALQIARGMSYLESHHCIFRNLACKNIVL
|  .. | ...    ... . |.  ..|..|||||.||.|.... |.||..|. .
LRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLV
Kinase AqueK453.AA Pkinase 842-933 17 2.8e-12 44.5 Pfam 175-293 (293) Show / Hide 
Range on Protein: 842-933
Range on HMM: 175-293/293
Sequence Identity: 17% (21 aa)

LRWTAPELLF-AGVCSSKSDVWSYGITLWEILTYGSKPYGEH----SSENVKEMVRQGHRIQLDGL----------------------ALPKNVHRLISE
... |||..  .   ..|.|.||.|..|.| |. |  |. .|    .  . ..|...  . .|.                        .....   .|. 
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

CWHQKPEERPSFKNLQER--L
|....|..||... . .   .
CLCKDPKKRPTAEQILQHPWF
Kinase AqueK453.AA FGFR 765-808 40 3.8e-09 27.28 In-house 119-169 (293) Show / Hide 
Range on Protein: 765-808
Range on HMM: 119-169/293
Sequence Identity: 40% (21 aa)

KKSSQT--------IADHTIFSYALQIARGMSYLESHHCIFRNLACKNIVLV
.|..|.        .      | | |.|||| ||.|  || | ||  | |||
RKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARN-VLV
Kinase AqueK453.AA Src 675-731 29 2.9e-08 24.14 In-house 1-56 (255) Show / Hide 
Range on Protein: 675-731
Range on HMM: 1-56/255
Sequence Identity: 29% (17 aa)

VSLQEFIHEGAHTQVFTGVFNRHQAVYAKVQKEGSSLSVYNFLSEAAVMRSLQHNNI
. | . . .|    |. |..| .  |  |. |.|. .|.  || || .| .|.|...
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGT-MSPEAFLQEAQIMKKLRHEKL
Kinase AqueK453.AA Fer 762-796 36 3e-07 20.87 In-house 98-133 (283) Show / Hide 
Range on Protein: 762-796
Range on HMM: 98-133/283
Sequence Identity: 36% (13 aa)

ERMKKSSQ-TIADHTIFSYALQIARGMSYLESHHCI
...||... |. | ... ...|.|.|| ||.|..||
SYLKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCI
Kinase AqueK453.AA Src 780-805 53 2e-06 17.51 In-house 103-128 (255) Show / Hide 
Range on Protein: 780-805
Range on HMM: 103-128/255
Sequence Identity: 53% (14 aa)

ALQIARGMSYLESHHCIFRNLACKNI
| |.|.||.||||   | | || .|.
AAQVAEGMAYLESMNYIHRDLAARNV
Kinase AqueK453.AA Fer 716-731 41 0.111845 1.62 In-house 55-71 (283) Show / Hide 
Range on Protein: 716-731
Range on HMM: 55-71/283
Sequence Identity: 41% (7 aa)

FLSEAAVMRS-LQHNNI
|. || .||. ..| |.
FMHEARIMRNNYDHPNV
Kinase AqueK453.AA Pkinase 703-790 20 0.15231 6.54 Pfam 33-124 (293) Show / Hide 
Range on Protein: 703-790
Range on HMM: 33-124/293
Sequence Identity: 20% (21 aa)

KVQKEGSSLSVYNFL-SEAAVMRSLQHNNIHQFISVTLLGTEQLCILHEPVYQLNLKECMERMKK-----SSQ---------TI--ADHTIFSYALQIAR
|...| |.  ..... ||...|..|.| ||     |.|... .    .  .|      .|| . .     .           ..   .... .|..||.|
KKRHEKSWKDQTHRRLSEIQIMKRLNHPNI-----VRLYDWFED---KDHIY-----MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILR

GMSYL
|. |.
GLEYC