Gene AqueK394 (A.queenslandica)

AqueK394

Species: A.queenslandica
Alias: AqueK394
External Links:
Annotation:

Classification

Group: TK
Family: REF

Sequence

Name Sequence Type Origin Length Description Download
AqueK394.AA Protein None 1300 None Fasta, JSON
AqueK394.kin_dom Protein Kinase Domain None 278 None Fasta, JSON

Protein domain

Protein domains of AqueK394.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK394.AA Pkinase_Tyr 828-1112 39 1.7e-131 445.93 Pfam 1-270 (270) Show / Hide 
Range on Protein: 828-1112
Range on HMM: 1-270/270
Sequence Identity: 39% (116 aa)

VILECEIGQGEFGEVYRGMLTDPTVTPHTRKILKETYSSSVAVKLLKPSATGSE--KKDFLNEIELMKQISQGHNSHVVNMVGCVT-AQEP--LCLITEF
...  ..|.|.|||||.| ...          ...     |||| ||..|. ..  ..||..|...|||.  ||. ..|...|..|  .||  .....|.
ITFGKKLGEGAFGEVYKGTWKG----------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQL--GHHPNIVRLYGVCTDQGEPNQIYIVMEY

VKHGDLLSYLRATRKRIPEDKVNPYPDLGELQSSDLLSFAYQIATGMEFLSSLDIVHRDLACRNVLIGDSKNLKISDYGMSRMVQAGDTY-VKSTKGKLP
..|||||.|||. |           .| . |  .|||....||| |||.|.|  ..|||||.||.|.....  ||.| |..| ..  |.| .|...||||
MPHGDLLDYLRKHR-----------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLP

LKWMAIESITDREFTSASDVWAYGVTLWEIGTLGGFP-YPTVGNDELLIRL-KQGYRMECPDNCSKEIYDIMLECWNESPLKRPTFSVLRQKV
 |||| |.| ...||..||||..||..||| |.|. | || . | |.. .. ..||||.||.||..||||.|..||.. | .||||| .... 
IKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc AqueK394.AA TyrKc 828-1112 37 3.2e-129 436.52 SMART 1-280 (280) Show / Hide 
Range on Protein: 828-1112
Range on HMM: 1-280/280
Sequence Identity: 37% (120 aa)

VILECEIGQGEFGEVYRGMLTDPTVTPHTRKILKETYSSSVAVKLLKPSATGSEKKDFLNEIELMKQISQG-HNSHVVNMVGCVTAQ-------EPLCLI
. |. ..| |.|||||.|...                   |||| ||..|    ..||..|...|...  | |. ..|...|..| |       |||...
ITLGKKLGEGAFGEVYKGTWK-----------------IQVAVKMLKEDA----REDFMREARIMCKL--GGHHPNIVRLYGVCTQQGRNFMYIEPLMIV

TEFVKHGDLLSYLRATRKRIPEDKVNPYPDLGELQSSDLLSFAYQIATGMEFLSSLDIVHRDLACRNVLIGDSKNLKISDYGMSRMVQAG-------DTY
.|...||||..|||..|..              |. .|||||..||| |||.|.|  ..|||||.||.|.|. .  |||| |.|| .  .       |.|
MEYMPHGDLKDYLRKHRPK--------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYY

VKST--KGK--LPLKWMAIESITDREFTSASDVWAYGVTLWEIGTLGGFPYPT-----VGNDELLIRLKQGYRMECPDN--------CSKEIYDIMLECW
.|..   ||  ||..|||.|.| ...||..||||..||..||| |.|. |||      . |.|.. ..||||||..|.|        |..|.|.||..||
RKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCW

NESPLKRPTFSVLRQKV
.| | .||||| .... 
HEDPEDRPTFSEIHECF
Kinase AqueK394.AA TK 828-1112 24 3.7e-114 384.25 In-house 1-486 (486) Show / Hide 
Range on Protein: 828-1112
Range on HMM: 1-486/486
Sequence Identity: 24% (118 aa)

VILECEIGQGEFG---EVYRGMLTDPTVTPHTRKIL-----------KETYSSSVAVKLLKPSATGSEKK-------------DFLNEIELMKQISQ--G
..|. ..|.|.||   |||.|.. ..     .| ..           ||     |||| ||. .. |..              |||.| | ||. ..  |
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HNSHVVNMVGCVTAQ------------EPLCLITEFVKHGD----LLSYLRATRKRIPEDKVNPY-----------------------------------
|  ..|...|..| .            ||.....|...|||    |..|||. |..  .   .|.                                   
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------PDLGELQSSDLLS-------------------FAYQIATGMEFLSSLDI------VHRDLACRNVLIGDSKN-----------LKISDYGMS--
      ... .|. .|||.                   ...||| |||.|.|. .      ||||||.||.|.|....            ||.|.|.|  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

------RMVQAGDTYVKST------------------------KGKLPLKWMAIESITDRE---------FTSASDVWAYGVTLWEIGTLG-GFPYPTVG
      | .. .| |....                        .||||..||| |...||.         ||..||||..||..||| |.| . .|. . 
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N---------DELLIRLKQG--------------YRMECPDNCS--------------KEIYDIMLECWNESPLKRPTFSVLRQKV
|         .|.. .|..|              .||..|..|.              .|.||.|..||.. | .||||| |... 
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK394.AA TK-Unique 828-1112 36 3.6e-106 359.02 In-house 1-294 (294) Show / Hide 
Range on Protein: 828-1112
Range on HMM: 1-294/294
Sequence Identity: 36% (110 aa)

VILECEIGQGEFGEVYRGMLTDPTVTPHTRKILKETYSSSVAVKLLKPSATGSEKKDFLNEIELMKQISQGHNSHVVNMVGCVTAQ-EPLCLITEFVKHG
. .. .||.|.||.|.||... ..         ..   ..||||.|| .||. .|.|||.||..||..  |   ..|...|| |   || ..| |..  |
LEVGDVIGEGAFGQVWRGEVWGIW--------KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKEL--GDHPNIVQCLGCCTKSDEPWMIIMEYCPCG

DLLSYLRATRKR-----------IPEDKVNPYPDLGELQSSDLLSFAYQIATGMEFLSS--LDIVHRDLACRNVLIGDSKNLKISDYGMSRMVQAGDTYV
.|..||| .|.            .  . ....| . .... ||..||.||| |||.|.|    ||||||. ||||... |..||.|.||.| |...  |.
NLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYS

KS-TKGKLPLKWMAIESIT--DREF-TSASDVWAYGVTLWEIGTLGGFPYPTVGNDELLIRLKQGYRMECPDNC-SKEIYDIMLECWNESPLKRPTFSVL
.. ..|..|..||| ||.   .. . |. ||||..||..||| |||..||| . ..... ....||||. |..| |.|.| .| .||...| .||.|. .
MMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQI

RQKV
... 
KHRL
Kinase AqueK394.AA UTK 828-1112 33 2.3e-99 336.39 In-house 1-296 (296) Show / Hide 
Range on Protein: 828-1112
Range on HMM: 1-296/296
Sequence Identity: 33% (104 aa)

VILECEIGQGEFGEVYRGMLTDPTVTPHTRKILKETYSSSVAVKLLKPSATGSEKKD----FLNEIE---LMKQISQGHNSHVVNMVGCVTAQEPLCLIT
|.|  ..|||.||||.....|...            | . |||| ....|..  ...    |..|     .||| .  .  .|...|| .|..||....|
VQLGRQLGQGAFGEVHKARFTQCS---------EHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFH--WHPNVLRLVGVCTQEEPWMIVT

EFVKHGDLLSYLRATRKRIPEDKVNPYPDLGELQSSD-LLSFAYQIATGMEFLSSLDIVHRDLACRNVLIGDS-------KNLKISDYG---MSRMVQA-
|. . |||.||||  |.  |        . ....... .|..|..|| ||..|.|  .||||||.||.|....          ||.|.|   |||.|.. 
EYMENGDLRSYLRRHRPTPP--------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTF

-------GDTYVKST-KGKLPLKWMAIESITDR-EFTSASDVWAYGVTLWEIGTLGGFPYPTVGNDELLIRLKQG--YRMECPDNCSKEIYDIMLECWNE
       .. |....  ...|..||| |..|..  ||..||||..||..||| | |  |||  .|.... ..  |  |||.||. |. ..|..|..||. 
HFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHY

SPLKRPTFSVLRQKV
.| .||.|  |.|..
DPQERPDFEDLVQQM
Kinase AqueK394.AA FGFR 828-1115 40 2.5e-90 306.42 In-house 1-293 (293) Show / Hide 
Range on Protein: 828-1115
Range on HMM: 1-293/293
Sequence Identity: 40% (125 aa)

VILECEIGQGEFGEVYRGMLTDPTVTPHTRKILKETYSSSVAVKLLKPSATGSEKKDFLNEIELMKQISQGHNSHVVNMVGCVTAQEPLCLITEFVKHGD
  |   .| | ||.| ..        .  ..|        |||| || ..|  .  |   |.| || |  | .  ..|  || | . ||  | |. .|| 
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEIT-------VAVKMLKMNHTDKDLSDLVSEMEMMKMI--GKHKNIINLLGCCTQEGPLYVIVEYCHHGN

LLSYLRATRKRIPEDKVNPY------PDLGELQ----------SSDLLSFAYQIATGMEFLSSLDIVHRDLACRNVLIGDSKNLKISDYGMSRMVQAGDT
|  .||| |   .. | ..       |   | |          . || |.|||.| |||.| |  ..||||| ||||..|   .||.|.| .| ..  | 
LRDFLRARRPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDY

YVKSTKGKLPLKWMAIESITDREFTSASDVWAYGVTLWEIGTLGGFPYPTVG-NDELLIRLKQGYRMECPDNCSKEIYDIMLECWNESPLKRPTFSVLRQ
| | | | || |||| |.  || .|. |||| ||| |||| |.|| |||..    ||   || |.||| | |||.||| .| .|| ..|  ||||  |  
YRKTTNGRLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQL--

KVDKL
 |. |
-VEYL
Kinase AqueK394.AA Src 828-1112 36 3.5e-85 289.31 In-house 1-255 (255) Show / Hide 
Range on Protein: 828-1112
Range on HMM: 1-255/255
Sequence Identity: 36% (105 aa)

VILECEIGQGEFGEVYRGMLTDPTVTPHTRKILKETYSSSVAVKLLKPSATGSEKKDFLNEIELMKQISQGHNSHVVNMVGCVTAQEPLCLITEFVKHGD
. |. ..||| ||||. |.  . |                |||| |||     . ..|| |...||. .  |. ..|..   ..  ||   .||. .|| 
IKLCRKLGQGQFGEVWMGYWNGNT---------------KVAVKTLKPGT--MSPEAFLQEAQIMKKLR--HE-KLVQLYAVCSQEEPIYIVTEYMSHGS

LLSYLRATRKRIPEDKVNPYPDLGELQSSDLLSFAYQIATGMEFLSSLDIVHRDLACRNVLIGDSKNLKISDYGMSRMVQAG-DTYVKSTKGKLPLKWMA
|| ||..             .. ..|.  .|...| |.| ||..|.|  ..||||| ||||.|..   |. | |  |... . | |. ..  |.| ||.|
LLDYLKK------------DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTA

IESITDREFTSASDVWAYGVTLWEIGTLGGFPYPTVGNDELLIRLKQGYRMECPDNCSKEIYD-IMLECWNESPLKRPTFSVLRQKV
 | |. . ||  |||| .|. |.|| | |  |||   | | | ....|||| ||.|| .|.|. |||.||...| .||||  |... 
PEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK394.AA KIN6 868-1112 39 5.4e-85 280.82 In-house 47-305 (305) Show / Hide 
Range on Protein: 868-1112
Range on HMM: 47-305/305
Sequence Identity: 39% (103 aa)

VAVKLLKPSATGSEKKDFLNEIELMKQISQGHNSHVVNMVGCVTAQEPLCLITEFVKHGDLLSYLRATRKRIP----------EDKVNP-YPDLGELQSS
.||| |   |.  .. ||. ||..|||   ||. |.||| ||||  ...||. |.  |.||| |||  .. .            .  |. | |   ..  
CAVKMLPSHADEMAHHDFMHEIAFMKQL--GHHPHLVNMLGCVTNSYKPCLVVEYCCHMDLLKYLRNRCQYMMNLDDLGINYHCPDENSRYDDMMCIRHK

DLLSFAYQIATGMEFLSSLDIVHRDLACRNVLIGDSK---NLKISDYGMSRMVQAGDTYVKSTKGK-LPLKWMAIESITDREFTSASDVWAYGVTLWEIG
||..||.||. |||.|.|  ..||||| ||||.  .      |||| |. |   .     .|  |. ||.|||| |..   ||   |||| .|| ..|. 
DLYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMDQFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMF

TLGGFPYPTVG-NDELLIRLKQGYRMECPDNCSKEIYDIMLECWNESPLKRPTFSVLRQKV
.||. |||..    |..  .. | |.. |..|..||||||  ||.| |  || |. .|.. 
SLGDVPYPEMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Kinase AqueK394.AA VEGFR 953-1112 49 2.2e-84 286.68 In-house 170-332 (332) Show / Hide 
Range on Protein: 953-1112
Range on HMM: 170-332/332
Sequence Identity: 49% (81 aa)

LQSSDLLSFAYQIATGMEFLSSLDIVHRDLACRNVLIGDSKNLKISDYGMSRM-VQAGDTYVKSTK-GKLPLKWMAIESITDREFTSASDVWAYGVTLWE
| . ||.....|.| |||||.|  ..||||| ||.|.  .. .||.| | .|     .. ||.... |.||.||||.||| |. .|. ||||.||| |||
LTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVFLWE

IGTLGGFPYPTVG-NDELLIRLKQGYRMECPDNCSKEIYDIMLECWNESPLKRPTFSVLRQKV
|..||| |||.|  ..|.  ||| ||||. || |  |||.|||.|| . |  ||.|| |  . 
IFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL
Kinase AqueK394.AA InsR 828-1114 34 3.6e-73 245.1 In-house 1-278 (278) Show / Hide 
Range on Protein: 828-1114
Range on HMM: 1-278/278
Sequence Identity: 34% (100 aa)

VILECEIGQGEFGEVYRGMLTDPTVTPHTRKILKETYSS--SVAVKLLKPSATGSEKKDFLNEIELMKQISQGHNSHVVNMVGCVTAQEPLCLITEFVKH
..|  | ||| || || |..         . |...  .    .|.| .. .|.  |. .|||| . ||..      |||.  | ..  .|   . |. ..
IVLIRECGQGSFGMVYEGIA---------KGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEF---NCHHVVRLLGVCSRGQPMYVVMEMMTY

GDLLSYLRATRKRIPEDK--VNPYP-DLGELQSSDLLSFAYQIATGMEFLSSLDIVHRDLACRNVLIGDSKNLKISDYGMSRMVQAGDTYVKSTKGKLPL
||| ||||. |   || .    ...        ..... | .|. || .| ..  ||||||||| .. ..   || | || | .   | | |..||.|| 
GDLKSYLRSRR---PEEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPV

KWMAIESITDREFTSASDVWAYGVTLWEIGTLGGFPYPTVGNDELLIRL-KQGYRMECPDNCSKEIYDIMLECWNESPLKRPTFSVLRQKVDK
 ||| ||..|  ||..|||| .|| |||. ||| .||    |.. |    . |  .. |.||..  ...|  ||  .|  ||||  . .    
RWMAPESLKDGVFTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase AqueK394.AA Ret 957-1114 49 1e-71 244.22 In-house 136-293 (293) Show / Hide 
Range on Protein: 957-1114
Range on HMM: 136-293/293
Sequence Identity: 49% (78 aa)

DLLSFAYQIATGMEFLSSLDIVHRDLACRNVLIGDSKNLKISDYGMSRMVQAGDTYVKSTKGKLPLKWMAIESITDREFTSASDVWAYGVTLWEIGTLGG
...||| ||  || .||.. .|||||| ||||. . . .||||.| .| |   | |||  |...| |||||||  |  .|. |||| .|| .||| |.|.
MIISFAWQICKGMHYLSEMKLVHRDLAARNVLVAEGRICKISDFGLTRDVYEDDSYVKRSKDRIPVKWMAIESLYDHVYTTKSDVWSFGVLCWEIVTMGA

FPYPTVGNDELLIRLKQGYRMECPDNCSKEIYDIMLECWNESPLKRPTFSVLRQKVDK
 ||| .  . |   || ||||. |.||| |.| ||. || . | ||| |  . .   |
NPYPGIPPERLWQLLKTGYRMDRPENCSEEMYRIMRQCWKQEPDKRPVFKFISKDFEK
Kinase AqueK394.AA RTKB 828-1112 33 1.5e-71 240.49 In-house 1-264 (264) Show / Hide 
Range on Protein: 828-1112
Range on HMM: 1-264/264
Sequence Identity: 33% (97 aa)

VILECEIGQGEFGEVYRGMLTDPTVTPHTRKILKETYSSSVAVKLLKPSATGSEKKDFLNEIELMKQISQGHNSHVVNMVGCVTAQEPLCLITEFVKHGD
| |  . |.| ||||... .  . ..  ..         |.|.| |||.|   |. ||. |. .|| .  |   .|. ..|     ||. |  |.  .| 
VWLGEKLGNGAFGEVFQAWVRNR-HMNTEQ---------SCAAKVLKPGASYEERQDFCSEMTVMKEL--GWHPNVIGIIGHCLQDEPYILLVELCELGN

LLSYLRATRKRIPEDKVNPYPDLGELQSSDLLSFAYQIATGMEFLSSLDIVHRDLACRNVLIGDSKNLKISDYGMSRMVQAGDTYVKSTKGKLPLKWMAI
|  |||. |         .  . . |... |..|. ||| || ||.. ...||||. ||||.. .   ||.|.||.| ..  .  .. |  .|| ||||.
LRDYLRMCRA--------SQHNPQSLKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREID--HECYETTCTRLPIKWMAP

ESITDREFTSAS-DVWAYGVTLWEIGTLGGFPYPTVGNDELLIRLKQGYRMECPDNCSKEIYDIMLECWNESPLKRPTFSVLRQKV
||. .| .|. | |||..||| ||| .||| ||..  | ...  |  |.|.. |   . ....||  || . . .||.|. | .  
ESWAHRIYTTKSGDVWSFGVTMWEIFSLGGTPYQQYRNGDIFYWLESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF
Kinase AqueK394.AA S_TKc 828-1116 21 7.8e-39 136.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 828-1116
Range on HMM: 1-231/231
Sequence Identity: 21% (64 aa)

VILECEIGQGEFGEVYRGMLTDPTVTPHTRKILKETYSSSVAVKLLKPSATGSEKKDFLNEIELMKQISQGHNSHVVNMVGCVTAQEPLCLITEFVKH--
  .  .||.| ||.||..  ..                  ||.| .|        .....||...|.    |  ..|.. ..    . |....|.. .  
YEILRKIGKGAFGKVYKCRHKK--------------TGRIVAIKIIK--------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDL

GDLLSYLRATRKR-----IPEDKVNPYPDLGELQSSDLLSFAYQIATGMEFLSSLDIVHRDLACRNVLIGDSKNLKISDYGMSRMVQAGDTYVKSTKGKL
|||..|..  ...     .||  .               ...|||. ..|.. |. |.||||   |.|. .  ..||.| |..| .         |    
GDLFDYIKKRGRHGLRFPFPE-HA--------------RFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCG

PLKWMAIESITDREFTS-ASDVWAYGVTLWEIGTLGGFPYPTVGNDELLIRLKQGYRMECPDNCSKEIYDIMLECWNESPLKRPTFSVLRQ-----KVDK
 . .|| | .    ..  ..|.|. |..|.|  . |  |.|   ........            |.|  |..  |..  | ||||   . |     | . 
TPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP

LL
 .
WF
Kinase AqueK394.AA Pkinase 828-1112 21 9.5e-30 106.26 Pfam 1-293 (293) Show / Hide 
Range on Protein: 828-1112
Range on HMM: 1-293/293
Sequence Identity: 21% (71 aa)

VILECEIGQGEFGEVYRGMLTDPTVTPHTRKILKETYSSSVAVKLLKPSATGSEKK--DFL-NEIELMKQISQGHNSHVVNMVGCVTAQEPLCLITEFVK
  ..  ||.| ||.||...  .                  |||| .| . . |.|.  ... .||..|| . .  |  .| . ....    .....|.. 
YHIGRKIGSGSFGCVYKCHHKGTGK--------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPN--IVRLYDWFEDKDHIYMVMEYCE

HG----DLLSYLRATRKRIPEDKVNPYPDLGEL--QSSDLLSFAYQIATGMEFLSSLDIVHRDLACRNVLIGDSKNL----KISDYGMSRMVQAGDTYVK
.|    || .|...              . | .  .  .. ...|||. |.|.. |  |.||||   |.|| .  ..    ||.| | .. ..    .. 
GGLYVMDLFDYIST-------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-

STKGKLPLKWMAIESIT-DREFTSASDVWAYGVTLWEIGTLGGFPYPTV-----GNDELLIRLKQG--YRMECPDNCS-------------------KEI
 |     . .|| | |  ... ....|.|..|..|.|  . | .|.|        ..  .|... |  .. ..|  ||                   .| 
MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEEC

YDIMLECWNESPLKRPTFSVLRQK--V
 |..  |..  | ||||.  . |   .
KDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK394.AA VEGFR 868-937 39 9.8e-18 63.61 In-house 32-102 (332) Show / Hide 
Range on Protein: 868-937
Range on HMM: 32-102/332
Sequence Identity: 39% (29 aa)

VAVKLLKPSATGSEKKDFLNEIELMKQISQGHNSHVVNMVGCVT---AQEPLCLITEFVKHGDLLSYLRATRK
|||| ||. || ||..  . |..... | . .|  |||. ||.|   .. ||  | |....| |..|||. |.
VAVKMLKEGATASEHRALMSELKMLIHIGHHLN--VVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRTKRM
Kinase AqueK394.AA Ret 868-937 42 5.6e-13 40.61 In-house 32-101 (293) Show / Hide 
Range on Protein: 868-937
Range on HMM: 32-101/293
Sequence Identity: 42% (31 aa)

VAVKLLKPS-ATGSEKKDFLNEIELMKQISQGHNSHVVNMVGCVTAQE--PLCLITEFVKHGDLLSYLRATRK
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VAVKMLKRNTANSSEYHDLLSEFQLLKQVN--H-PHVIKLYGACIQDDPFPTCLIVEYCKYGCLREFLRLSRK
Kinase AqueK394.AA Ret 828-845 33 0.02944 3.46 In-house 1-18 (293) Show / Hide 
Range on Protein: 828-845
Range on HMM: 1-18/293
Sequence Identity: 33% (6 aa)

VILECEIGQGEFGEVYRG
 .|. . | |.|| | ..
LQLDDTLGEGHFGQVVKA