Gene AqueK268 (A.queenslandica)

AqueK268

Species: A.queenslandica
Alias: AqueK268
External Links:
Annotation:

Classification

Group: TK
Family: Eph

Sequence

Name Sequence Type Origin Length Description Download
AqueK268.AA Protein None 122 None Fasta, JSON
AqueK268.kin_dom Protein Kinase Domain None 71 None Fasta, JSON

Protein domain

Protein domains of AqueK268.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr AqueK268.AA Pkinase_Tyr 1-121 42 4.4e-56 190.55 Pfam 82-200 (270) Show / Hide 
Range on Protein: 1-121
Range on HMM: 82-200/270
Sequence Identity: 42% (52 aa)

MMIVLELIPHGDMRQYLHTLQPQPGELVASTVPGLLLSFCRQIASGMEYLSKKGFVHRDLAARNILIADHEMCRIADFGMPRDL-HDENY-CVSNAKMIP
..||.|. ||||.. ||..      |   .  .  ||..|.|||.|||||. |...||||||||.|...   ..|.|||. ||. .|..|  ..   ..|
IYIVMEYMPHGDLLDYLRKHR----EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLP

VKWTAPEALNYRRYSSASDVWSY
.||.|||..||......|||||.
IKWMAPECINYGKFTTKSDVWSF
Kinase AqueK268.AA TK 1-121 23 4.4e-53 175.9 In-house 130-380 (486) Show / Hide 
Range on Protein: 1-121
Range on HMM: 130-380/486
Sequence Identity: 23% (58 aa)

MMIVLELIPHGD----MRQYLHTL---------------------------------------------------------QPQPGELVA----------
.|||.|. ||||     |.||..                                                          . .  .|.           
WMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCK

-STVPGLLLSFCRQIASGMEYLSKK------GFVHRDLAARNILIADHEM-----------CRIADFGMP--------RDL-HDENYCVSN---------
    .  || .|.|||.|||||..|      .||||||||||.|....             |.|||||.         ||. .|..|....         
HQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMW

---------------AKMIPVKWTAPEALN---------YRRYSSASDVWSY
                 ..|..|.|||.||         |......|||||.
PFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSF
Kinase AqueK268.AA UTK 1-121 37 1.1e-50 171.55 In-house 85-226 (296) Show / Hide 
Range on Protein: 1-121
Range on HMM: 85-226/296
Sequence Identity: 37% (53 aa)

MMIVLELIPHGDMRQYLHTLQPQPGELVASTVPGLLLSFCRQIASGMEYLSKKGFVHRDLAARNILIADH-------EMCRIADFG---MPRDLH-----
.|||.|. . ||.|.|| .  |.|..  ..     .|.....||.||.||. .|||||||||||.|...|       . |.|||||   | |...     
WMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFS

----DENYCVSN-AKMIPVKWTAPEALNYR-RYSSASDVWSY
    . .|. .. ....|..|.|||||... |....|||||.
NRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSF
Kinase AqueK268.AA Src 3-121 42 1.2e-42 142.74 In-house 71-186 (255) Show / Hide 
Range on Protein: 3-121
Range on HMM: 71-186/255
Sequence Identity: 42% (51 aa)

IVLELIPHGDMRQYLHTLQPQPGELVASTVPGLLLSFCRQIASGMEYLSKKGFVHRDLAARNILIADHEMCRIADFGMPRDLH--DENYCVSNAKMIPVK
|| |.  ||   .||.      ||  .  .|  |...  |.|.||.||... ..||||||||.|. .. .| .||||  | .   |..|| .   ..|.|
IVTEYMSHGSLLDYLKK----DGEGRHLHLP-QLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIK

WTAPEALNYRRYSSASDVWSY
||||||.||.|..  |||||.
WTAPEAINYGRFTIKSDVWSF
Kinase AqueK268.AA TK-Unique 1-121 34 2.3e-39 133.4 In-house 80-225 (294) Show / Hide 
Range on Protein: 1-121
Range on HMM: 80-225/294
Sequence Identity: 34% (51 aa)

MMIVLELIPHGDMRQYLHTLQPQ-----------------PGELVASTVP-GLLLSFCRQIASGMEYLSK--KGFVHRDLAARNILIADHEMCRIADFGM
.||..| .| |. . ||.| .|.                 | .   ...  ..|..|. |||.|||||..  |..|||||.|||.|.... .| |.||||
WMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGM

PRDLHDENYCVSNAK--MIPVKWTAPEALN--YRRY-SSASDVWSY
 ||.....  ... .  .||..| |||.|   .. | .. |||||.
ARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSF
Kinase AqueK268.AA SRM 3-121 45 4.1e-39 128.37 In-house 72-184 (253) Show / Hide 
Range on Protein: 3-121
Range on HMM: 72-184/253
Sequence Identity: 45% (54 aa)

IVLELIPHGDMRQYLHTLQPQPGELVASTVPGLLLSFCRQIASGMEYLSKKGFVHRDLAARNILIADHEMCRIADFGMPRDLHDENYCVSNAKMIPVKWT
|. || . | . ||| .    . | . .  .  || |  |.| || ||  . ..||||||||.|. |  .|...|||. | . |  |  |    ||.|||
IITELMRKGNLQQYLRD----SDEKALPIPH--LLDFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWT

APEALNYRRYSSASDVWSY
||||.||| ||  |||||.
APEAANYRHYSQKSDVWSF
Kinase AqueK268.AA Fer 2-121 37 1.7e-38 128.81 In-house 85-204 (283) Show / Hide 
Range on Protein: 2-121
Range on HMM: 85-204/283
Sequence Identity: 37% (47 aa)

MIVLELIPHGDMRQYLHTLQPQPGELVASTVPG-LLLSFCRQIASGMEYLSKKGFVHRDLAARNILIADHEM---CRIADFGMPRDLHDENYCVS---NA
|||.|....|. . || . . .       ||.   .. .| |.|.||||| .|. .|||.||||.|. ...    | |.|||| |.. |. |  .    |
MIVMEFCNGGSLDSYLKKNKNK-------TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKA

KMIPVKWTAPEALNYRRYSSASDVWSY
...|..|.|||..... ||...||||.
CKVPIRWLAPETWQTGIYSPKTDVWSF
Kinase AqueK268.AA Eph 43-121 53 1e-37 124.17 In-house 114-196 (264) Show / Hide 
Range on Protein: 43-121
Range on HMM: 114-196/264
Sequence Identity: 53% (45 aa)

IASGMEYLSKKGFVHRDLAARNILIADHEMCRIADFGMPRDLHDEN-----YCVSNAKMIPVKWTAPEALNYRRYSSASDVWSY
||||| |||  ..|||||||||||.  . .| ..|||. | | |.      |  .    ||..||||||. ||...||||||||
IASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSASDVWSY
Kinase AqueK268.AA Src-Unclassified 42-121 47 8.3e-36 120.22 In-house 127-213 (284) Show / Hide 
Range on Protein: 42-121
Range on HMM: 127-213/284
Sequence Identity: 47% (41 aa)

QIASGMEYLSKKGFVHRDLAARNILIADHE-----MCRIADFGMP--RDLHDENYCVSNAKMIPVKWTAPEALNYRRYSSASDVWSY
|.||||.||. |. |||||||||.|| .          ..|||    ..  |.|||     | |.||.|||.  |   |  ||||||
QVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFIYGNFSIKSDVWSY
Kinase AqueK268.AA Ack 34-121 45 3.1e-35 116.29 In-house 105-197 (266) Show / Hide 
Range on Protein: 34-121
Range on HMM: 105-197/266
Sequence Identity: 45% (42 aa)

GLLLSFCRQIASGMEYLSKKGFVHRDLAARNILIADHE-MCRIADFGMPRDL-HDENYCVSNAKM---IPVKWTAPEALNYRRYSSASDVWSY
..|. ||.|||.|| ||  |...|||||||||| .  . .  |.|||  | |   |.| ... .    .|  | |||.|..|. |.|||||..
HTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMF
Kinase AqueK268.AA Tec 1-121 40 9.2e-35 118.92 In-house 69-184 (254) Show / Hide 
Range on Protein: 1-121
Range on HMM: 69-184/254
Sequence Identity: 40% (49 aa)

MMIVLELIPHGDMRQYLHTLQPQPGELVASTVPGLLLSFCRQIASGMEYLSKKGFVHRDLAARNILIADHEMCRIADFGMPRDLHDENYCVSN-AKMIPV
. || | . ||    || . .   ... ...  ..||. | ..  ||.|| ...|.|||||||| |. | .   ..|||| |   |  |  |  .|  ||
IYIVTEYMEHGCLLNYLREHK---HHFQKNM--AILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKF-PV

KWTAPEALNYRRYSSASDVWSY
|| .|| ..| |||| ||||..
KWCPPEVFHYSRYSSKSDVWAF
Kinase AqueK268.AA TyrKc 1-122 19 7.3e-12 -30.82 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-122
Range on HMM: 1-280/280
Sequence Identity: 19% (55 aa)

M-------------------------------------------------------------------------MIVLELIPHGDMRQYLHTLQPQPGEL
                                                                          |||.|. |||| ..||.  .|.    
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK----

VASTVPGLLLSFCRQIASGMEYLSKKGFVHRDLAARNILIADHEMCRIADFGMPRDLHDE--------NYCVS---NAKM-IPVKWTAPEALNYRRYSSA
     .  ||||| |||.|||||..|...||||||||.|...   ..|.|||. ||..|.         | ..   ..|. .|..|.|||..||......
---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

SDVWSY--------------------------------------------------------------------------------X
|||||.                                                                                 
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK268.AA Pkinase 3-121 24 1.3e-11 42.17 Pfam 77-198 (293) Show / Hide 
Range on Protein: 3-121
Range on HMM: 77-198/293
Sequence Identity: 24% (32 aa)

IVLELIPHG----DMRQYLHTLQPQPGELVASTVPGLLLSFCRQIASGMEYLSKKGFVHRDLAARNILIADHEMC----RIADFGMPRDLHDENYCVSNA
.|.|. ..|    |   |..|   . .  .    .  . ....||..|.||. ..|..||||   |||| ..  .    .|.|||  . .    |  .  
MVMEYCEGGLYVMDLFDYIST---WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-

KMIPV---KWTAPEALN-YRRYSSASDVWSY
 . ..    . ||| .. .. |....|.||.
MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC