Gene AqueK235 (A.queenslandica)

AqueK235

Species: A.queenslandica
Alias: AqueK235
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: PAKA

Sequence

Name Sequence Type Origin Length Description Download
AqueK235.AA Protein None 503 None Fasta, JSON
AqueK235.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of AqueK235.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PBD AqueK235.AA PBD 51-109 53 2.3e-26 94.38 Pfam 1-60 (60) Show / Hide 
Range on Protein: 51-109
Range on HMM: 1-60/60
Sequence Identity: 53% (32 aa)

EISSP-TGFEHTVHVGFDPVSGEFTGMPEAWAKLLDSSGISQAEKAKNPDAVVKALEFMT
.||.| | |.||.|||.|. .|.|||||. |.|||.|||||. |  .||.||.... |  
MISTPLTNFKHTMHVGWDGQTGFFTGMPPEWQKLLQSSGISKPEQKHNPQAVFDVVQFYQ
PBD AqueK235.AA PBD 52-87 52 2.7e-16 61.39 SMART 1-38 (38) Show / Hide 
Range on Protein: 52-87
Range on HMM: 1-38/38
Sequence Identity: 52% (20 aa)

ISSPT-GFEHTVHVG-FDPVSGEFTGMPEAWAKLLDSS
||.||  |.|.|||| .|. .|||||.|. |..|| ..
ISTPTGNFKHIVHVGPWDGQTGEFTGLPHQWQHLLKHC
Kinase AqueK235.AA PAKA 228-480 70 6.8e-198 663.72 In-house 1-260 (260) Show / Hide 
Range on Protein: 228-480
Range on HMM: 1-260/260
Sequence Identity: 70% (185 aa)

YTKMEKIGQGASGVVYTASEIATGNE--VAIKQMNLQQQPKKELIINEIIVMKEIKQPNIVNFLDSYLVGESELWVVMEYLAGGSLTDVVTETC------
|..|||||||||| ||.| .|.|..|  |||||||...||||||||||| |||| |..||||..||||| ..||||||||..||.||||.|..|      
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLV-DDELWVVMEYMEGGCLTDVITQCCNIQCNY

MNEGQIAAVCRECLQALKFLHDNHVIHRDIKSDNILLGMDGQVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKQYGPKVDIWSLGIMAIEMVEG
|.|||||.|||||||.|.|.|..|.||||||||||||||||.||.||||||||.|.||.||.|||||||||||||..||||..||||||||||||||.||
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEG

EPPYLNENPLRALYLIATNGTPELQNPENLSRVFRDFLDRCLEMEVDKRGSASELLTHVFL
|||||||.||||.|||||||.|....|...|  |.||||.||...||.| ||.|||.| ||
EPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase AqueK235.AA STE20 228-480 50 9.5e-165 553.61 In-house 1-288 (288) Show / Hide 
Range on Protein: 228-480
Range on HMM: 1-288/288
Sequence Identity: 50% (144 aa)

YTKMEKIGQGASGVVYTASEIATGNE----VAIKQMNLQQQ----PKKELIINEIIVMKEIKQPNIVNFLDSYLVG---ESELWVVMEYLAGGSLTDVVT
|...||||||..|.||.| .. ||..    ||||.||| ..    ...|.|..|| .||. | ||||....|||..   ..|||.||||..||||||...
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

ETC----------MNEGQIAAVCRECLQALKFLHDNHVIHRDIKSDNILLGMDGQVKLTDFGFCAQITP-----EQSKRSTMVGTPYWMAPEVVTR----
...          ||| |||..|||.||.|..|| ||.||||||.|||||..||.|||.|||.|||.|.     .|.|| |.|||||||||||. .    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-KQYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA--TNGTPELQN--PENLSRVFRDFLDRCLEMEVDKRGSASELLTHVFL
 |.|. |.|||||||.||||.||||||....|.||...|.  .|..|.|..  |.. |  |.||.|.||.....|| .||.||.| |.
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase AqueK235.AA PAKB 229-480 56 5.3e-132 444.82 In-house 2-252 (252) Show / Hide 
Range on Protein: 229-480
Range on HMM: 2-252/252
Sequence Identity: 56% (143 aa)

TKMEKIGQGASGVVYTASEIATGNEVAIKQMNLQQQPKKELIINEIIVMKEIKQPNIVNFLDSYLVGESELWVVMEYLAGGSLTDVVTETCMNEGQIAAV
..  ||| |  |.|  | |. ||  ||.|.|.|  |   ||  ||. .| . . ||||.. .|||||. |||||||.. ||.|||.||.| ||| |||.|
DNYVKIGEGSTGIVCIATEKHTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYQHPNIVEMYSSYLVGD-ELWVVMEFMEGGALTDIVTHTRMNEEQIATV

CRECLQALKFLHDNHVIHRDIKSDNILLGMDGQVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKQYGPKVDIWSLGIMAIEMVEGEPPYLNENP
|| .|||| .||   ||||||||| |||  ||.|||.|||||||.  |  ||  .|||||||||||. |  ||..||||||||| ||||.||||| || |
CRQVLQALAYLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFNEPP

LRALYLIATNGTPELQNPENLSRVFRDFLDRCLEMEVDKRGSASELLTHVFL
|.|.  |  .  | |.|    | . |.||||.|  .. .| .| ||| | ||
LQAMKRIRDMHPPRLKNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL
Kinase AqueK235.AA STE 228-480 33 7.69999999999e-129 434.32 In-house 1-359 (359) Show / Hide 
Range on Protein: 228-480
Range on HMM: 1-359/359
Sequence Identity: 33% (121 aa)

YTKMEKIGQGASGVVYTASEI------ATGNE---------VAIKQMNLQQQ-----------------PKKELIINEIIVMKEIK--QPNIVNFLDSYL
....||||.||.|.||.|  .       ||..         .|||||||...                  ... |..|| .||. .   ||||.....|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG------ESELWVVMEYLAGGSLTDVVTETC---------------MNEGQIAAVCRECLQA-LKFLHDNHVIHRDIKSDNILLGMDGQVKLTDFGFCA
..      ..|||..|||..||||.|.. ...               ..| |||..||..|.. |..||..|.||||||..||||     |||.|||.|.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QITPE----------------QSKRSTMVGTPYWMAPEVVTR------KQYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATN-----------
|.|..                |.|| |.|||| ||||||...      |.|. |.||||||...|||..|.||. ...|.||...|..|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----GTPELQN-----------------PENLSRVFRDFLDRCLEMEVDKRGSASELLT--HVFL
    . | |..                 |...|  |.||...||... .|| .||.||   | |.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK235.AA YSK 228-480 43 2.2e-108 327.47 In-house 1-257 (257) Show / Hide 
Range on Protein: 228-480
Range on HMM: 1-257/257
Sequence Identity: 43% (113 aa)

YTKMEKIGQGASGVVYTASEIATGNEVAIKQMNLQQQPKK-ELIINEIIVMKEIKQPNIVNFLDSYLVGESELWVVMEYLAGGSLTDVVTE---TCMNEG
.|| |.|| |  |.|| . .  |.  ||||  .| .     |.|  || .  . ..|.| ... ||| . . ||..|||..|||. |         . | 
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKD-TKLWIIMEYCGGGSCLDLMKPKYVGQFDEK

QIAAVCRECLQALKFLHDNHVIHRDIKSDNILLGMDGQVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTR--KQYGPKVDIWSLGIMAIEMVEGEP
.|| . || |..|..|| . .||||||. |.||  .|.||| |||  .|||  | || |.|||||||||||.     .|  |.||||||| |.||  |||
YIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEP

PYLNENPLRALYLIATNGTPELQNPENLSRVFRDFLDRCLEMEVDKRGSASELLTHVFL
||    |.|.. ||  |  |.|.  .. |  | .| . ||. .  .| ||.||| | | 
PYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase AqueK235.AA MST 228-480 44 2.4e-100 319.65 In-house 1-254 (254) Show / Hide 
Range on Protein: 228-480
Range on HMM: 1-254/254
Sequence Identity: 44% (114 aa)

YTKMEKIGQGASGVVYTASEIATGNEVAIKQMNLQQQPKKELIINEIIVMKEIKQPNIVNFLDSYL-VGESELWVVMEYLAGGSLTDVV--TETCMNEGQ
....||.|||. |.|| |  . ||..||||...       . ||.||  |.. | ..|| . .||.   ....| |||| ..||. |..  |    || |
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV--NEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQ

IAAVCRECLQALKFLHDNHVIHRDIKSDNILLGMDGQVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKQYGPKVDIWSLGIMAIEMVEGEPPYL
||....  || |. ||||. ||||||. ||||  .|  || |||  .| |  . || | .|||||||||| .   |  |.||||||| |||| ||.||| 
IACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYS

NENPLRALYLIATNGTPELQNPENLSRVFRDFLDRCLEMEVDKRGSASELLTHVFL
.  | ||. .| ..  | ...||  |  | ||. .||  . ..| .| .|| | | 
DIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase AqueK235.AA S_TKc 228-480 31 1.7e-97 331.16 SMART 1-231 (231) Show / Hide 
Range on Protein: 228-480
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

YTKMEKIGQGASGVVYTASEIATGNEVAIKQMNLQQQPKKELIINEIIVMKEIKQPNIVNFLDSYLVGESELWVVMEYLAG--GSLTDVVTETC------
|....|||.|| |.|| . .. || .||||...       | |..|| ..|. . ||||...|..    ..|..||||. |  |.| |.  .        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-MNEGQIAAVCRECLQALKFLHDNHVIHRDIKSDNILLGMDGQVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKQYGP-KVDIWSLGIMAIEMV
 ..| ... .... ..||...|....||||.| .||||    ..|..|||...|.       .|..|||..|||||.   .||. |.|.||.|.. .||.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

EGEPPYLNENPLRALYLIATNGTPELQNPENLSRVFRDFLDRCLEMEVDKRGSASELLT-------HVFL
 |.||.   .. . . .|              |. ..||...||... .|| .| |.|.       | ..
CGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK235.AA Pkinase 228-480 28 1.9e-94 324.85 Pfam 1-293 (293) Show / Hide 
Range on Protein: 228-480
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

YTKMEKIGQGASGVVYTASEIATGNEVAIKQMNLQQQPKKELIIN----EIIVMKEIKQPNIVNFLDSYLVGESELWVVMEYLAGG----SLTDVVT---
|.. .|||.|..|.|| . .. || .||.|..... . .......    || .||... |||| ..|..   ......||||. ||    .| |...   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR

ETCM--NEGQIAAVCRECLQALKFLHDNHVIHRDIKSDNILLGMDGQV----KLTDFGFCAQI-TPEQSKRSTMVGTPYWMAPEVVT-RKQYGPKVDIWS
..|.   | ..  .... |..|...|.. .||||.|..|||.  .|..    |..|||...|. .  .|  .| .|||..|||||.  .. ||||||.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGIMAIEMVEGEPPYLNE----NPLRALYLIATNGTPELQNPENLS---------------------RVFRDFLDRCLEMEVDKRGSASELLTHVFL
.|.. .||. |.||. ..    | .. ...|. .. |.|  ..  .                     . ..||...||..   || .| ..| | ..
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK235.AA TAO 228-480 44 5.7e-78 254.24 In-house 1-254 (254) Show / Hide 
Range on Protein: 228-480
Range on HMM: 1-254/254
Sequence Identity: 44% (115 aa)

YTKMEKIGQGASGVVYTASEIATGNEVAIKQMNL---QQQPKKELIINEIIVMKEIKQPNIVNFLDSYLVGESELWVVMEYLAGGSLTDV--VTETCMNE
.. .. || |. | || | .  | . ||||.|.    | . | . || |.  ....|.||....   ||  |.  |.||||   || .|.  |    | |
FQDLREIGHGSFGAVYFARDKHTEEVVAIKKMSYSGKQSHEKWQDIIKEVRFLQQVKHPNCIEYKGCYLR-EHTCWLVMEYCL-GSASDILDVHKKPMQE

GQIAAVCRECLQALKFLHDNHVIHRDIKSDNILLGMDGQVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVV---TRKQYGPKVDIWSLGIMAIEMVEG
  |||.|.. ||.|..||  ..||||||  ||||  .|||||.|||  . . | .|     |||||||||||.      ||  |||.|||||  ||. | 
VEIAAICHGALQGLRYLHSHKMIHRDIKAGNILLTEHGQVKLADFGSASMVCPANS----FVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAER

EPPYLNENPLRALYLIATNGTPELQNPENLSRVFRDFLDRCLEMEVDKRGSASELLTHVFL
 ||. | | . ||| || |  | ||..|  |  |..|.| ||. . ..| || |.|.| |.
KPPLFNMNAMSALYHIAQNDSPTLQQNE-WSDCFHQFVDKCLQKMPQERPSAEECLRHEFV
Kinase AqueK235.AA KHS 228-480 42 9.3e-78 261.09 In-house 1-258 (258) Show / Hide 
Range on Protein: 228-480
Range on HMM: 1-258/258
Sequence Identity: 42% (111 aa)

YTKMEKIGQGASGVVYTASEIATGNEVAIKQMNLQQQPKKELIINEIIVMKEIKQPNIVNFLDSYLVGESELWVVMEYLAGGSLTDVVTET-CMNEGQIA
|  . ..| |  | || | .|.... .|.| . .. .   ..|  ||..||. . |||| .  |||  .  ||..|||  |||| |.   |  ..| |||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRD-KLWICMEYCGGGSLQDIYHVTGPLSELQIA

AVCRECLQALKFLHDNHVIHRDIKSDNILLGMDGQVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV--VTRK-QYGPKVDIWSLGIMAIEMVEGEPPY
 |||| ||.|..|| .  .|||||  ||||  .|.||| |||  ||||   .||   .||||||||||  | ||  |.   |||..|| |||. |  || 
YVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPM

LNENPLRALYLIATNG--TPELQNPENLSRVFRDFLDRCLEMEVDKRGSASELLTHVFL
 .  |.|||.|..  .   |.|.. .  |  | .|.  .|  .  || .|. ||.| |.
FDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase AqueK235.AA STE11 228-480 33 5.5e-76 258.74 In-house 1-303 (303) Show / Hide 
Range on Protein: 228-480
Range on HMM: 1-303/303
Sequence Identity: 33% (101 aa)

YTKMEKIGQGASGVVYTASEIATGNEVAIKQMNLQQQPK----------K----ELIINEIIVMKEIKQPNIVNFLDSYLV--GESELWVVMEYLAGGSL
..| |.||.|| |.||..  . || ..|.||. .| . .          .    ..|  || .|| .. .||| .... |    .... . ||| .||||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

TDVVTET--C--MNEGQIAAVCRECLQALKFLHDNHVIHRDIKSDNILLGMDGQ-VKLTDFGFCAQITPEQSKRST----------MVGTPY--------
 ..      .  ..|  |    .  |..|..||....|||||| .||||  ||. .||.||| . ..  . .. ..          | ||||        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

WMAPEVVTRKQ---YGPKVDIWSLGIMAIEMVEGEPPYLNE--NPLRALYLIATNGTPELQNPENLS------RVFRDFLDRCLEMEVDKRGSASELLTH
||||||... .   || |.||||||   |||. | ||. |   |.  |.. |... .|  . ||..|         ||||..|.| .  || .|..|| |
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

VFL
 |.
PFI
Kinase AqueK235.AA SLK 228-480 39 1.3e-75 254.51 In-house 1-259 (259) Show / Hide 
Range on Protein: 228-480
Range on HMM: 1-259/259
Sequence Identity: 39% (102 aa)

YTKMEKIGQGASGVVYTASEIATGNEVAIKQMNLQQQPKKELIINEIIVMKEIKQPNIVNFLDSYLVGESELWVVMEYLAGGSLTDVVTE--TCMNEGQI
.  .  .| || | || | .  ..   | | ...... . |  . || .. |.| ||||. ...| . . .||...|. .|| .  .. |    . | ||
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYY-DNKLWMMIEFCDGGAVDNIMVELEHPLTEDQI

AAVCRECLQALKFLHDNHVIHRDIKSDNILLGMDGQVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVV---TRKQ--YGPKVDIWSLGIMAIEMVEGE
. ||.. ..||..||.|.|||||.|  |||. |||.|.| |||  |. . .  || | .|||||||||||   | |   |  |.|||||||  ||| ..|
QYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQME

PPYLNENPLRALYLIATNGTPELQNPENLSRVFRDFLDRCLEMEVDKRGSASELLTHVFL
||. . ||.| |  |.    |.|..|   |. |.||| .||. ....| ....|. | ..
PPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase AqueK235.AA Pkinase_Tyr 228-423 27 4.5e-25 85.55 Pfam 1-216 (270) Show / Hide 
Range on Protein: 228-423
Range on HMM: 1-216/270
Sequence Identity: 27% (60 aa)

YTKMEKIGQGASGVVYTASEI----ATGNEVAIKQMNLQQQPK---KELIINEIIVMKEI-KQPNIVNFLDSYL-VGES-ELWVVMEYLAGGSLTDVVTE
 |...|.|.|| |.|| .        |. .||.| .. .  ..   .|  ..|. .||.. . ||||...   .  ||. ....|||| ..|.| |   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

T-----CMNEGQIAAVCRECLQALKFLHDNHVIHRDIKSDNILLGMDGQVKLTDFGFCAQI--TPEQ-SKRSTMVGTPYWMAPEVVTRKQYGPKVDIWSL
        .  ..   |..  ... .|.... ||||.   |.|.. ...|| .||| .  |  . .   ||.       |||||.   . .  | |.|| 
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GIMAIEMVE-GEPP-Y
|.   |..  || | |
GVLMWEIFTYGEQPTY
Kinase AqueK235.AA TyrKc 228-478 22 1.2e-23 85.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 228-478
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YTKMEKIGQGASGVVYTASEIATGNEVAIKQMNLQQQPKKELIINEIIVMKEI--KQPNIVNFLDSYLVGE------SELWVVMEYLAGGSLTDVVTETC
 |. .|.| || |.|| .  .    .||.| ..      .| ...|. .|...  . ||||...   . ..        |..|||| ..|.| |   .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--MNEGQIAAVCRECLQALKFLHDNHVIHRDIKSDNILLGMDGQVKLTDFGFCAQITPE----QSKRSTMV----GTP-----YWMAPEVVTRKQYGPKV
   .  .    |    .   .||....||||.   |.|.| ...|| .||| .  |. .     ||   ..    |.       |||||.   . . .| 
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DIWSLGIMAIEMVE-GEPPYLN-----ENPLRALYLIATNGTPELQNPEN--------LSRVFRDFLDRCLEMEVDKRGSASELLTHV
|.|| |..  |.   |..|| .      .. ... .. . .   .  |.|         .    .   .| . . ..| . ||.    
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYR--MPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF