AqueK002

Species: A.queenslandica
Alias: AqueK002
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
AqueK002.AA Protein None 481 None Fasta, JSON
AqueK002.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of AqueK002.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH AqueK002.AA PH 8-113 21 3.8e-16 60.88 Pfam 1-92 (92) Show / Hide
Range on Protein: 8-113
Range on HMM: 1-92/92
Sequence Identity: 21% (23 aa)

VVKEGWLQKRGEYIKNWRPRWFILYSDGSFRGFKNKPEDKFKSDQDPLNNFRIDADAHVIIATDKS-KKFGFIVRCLQITTLIERNLATDTETERVEWIS
|.||||| |.| ..|.|..|||.| . .    .|...             . |. .   .  .... ....| .|. .     .  .....| |. .|..
VIKEGWLHKKG-KRKSWKKRWFVLFN-NCLYYYKDDK---------YRPKGSIPLSDCQVTKVPDNKRPHCFQIRT-DR---RTYYFQAESEEEMNDWMQ

AIKKVIS
||.....
AIQSACR

PH AqueK002.AA PH 8-115 23 2.4e-15 58.24 SMART 1-82 (82) Show / Hide
Range on Protein: 8-115
Range on HMM: 1-82/82
Sequence Identity: 23% (25 aa)

VVKEGWLQKRGEYIKNWRPRWFILYSDGSFRGFKNKPEDKFKSDQDPLNNFRIDADAHVIIATDKSKKFGFIVRCLQITTLIERNLATDTETERVEWISA
|.||||| |..    .|..|||.|.. ...  .|.|         .|   . ..    |   .      .| ... .     .  .....| |. ||..|
VIKEGWLYKKS--K-RWKKRWFVLFN-DCLYYYKDK---------KPKGSIPLSDC-TVRE-P------CFEIHH-DR----TYYFQCESEEEMQEWMQA

IKKVISYL
|.|.|. .
IQKAIHNN

Kinase AqueK002.AA Akt 152-409 57 7.29999999999e-200 644.68 In-house 1-264 (264) Show / Hide
Range on Protein: 152-409
Range on HMM: 1-264/264
Sequence Identity: 57% (152 aa)

FEMLKVLGKGTFGKVVLCREKSTDEIF-AMKILKKDVIVAKDEITHTLTENRVLQSTKHPFLTQLKYSFQTADRLCFVMEYVNGGELFFHLSVEKMLTEE
|..|||||||.||||.|...|.|.... |||.||||.|..|... ||.||...|| ..|||...|.|||||.|.|.|||.|.||||||.||. ..  .|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

RTRFYGAEITLAIGYLHSLGVVYRD-LKLENLLLDRDGHIKLTDFGLCKEE-ISYGATTRTFCGTPEYLAPEVLEDNDYGRAVDWWG-LGVVMYEMMCGR
|.|||.||| |||..||| ...||| ||.||.|.|.||||.|||||||||. |... .| ||||||||||||.|..|....|||||| ||.|||||||||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

LPFYSRDHEVLFELILVEEVKFP--SRLSTLAKDLLDRLLTKAPERRLGGGPDGVEEVKAHPFF
.|||..||...|..|. ..||||  ...|  .|||. .||.| |..||||||....|.|.||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF

Kinase AqueK002.AA AGC 152-409 37 6.00000000001e-198 517.74 In-house 1-395 (395) Show / Hide
Range on Protein: 152-409
Range on HMM: 1-395/395
Sequence Identity: 37% (151 aa)

FEMLKVLGKGTFGKVVLCREK------STDEIFAMKILKKDV-IVAKD--EITHTLTE------------NRVLQSTK----------HPFLTQ-LKYSF
||.|||.|||.|||| |.|.|      .|....|||.|||.. || |.  .. ||.||             ..|.  .          |||... |.|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTADR--LCFVME----YVN-----GG-ELFFHLS---VEKMLTEERTRFYGAE-------ITLAIGYLHS-LGVVYRD-LKLENLLLDRDGHIKLTDFG
|. |.  |.||||    |||     || |||.||     |. ..|||.||| ||       |.||. |||| .|...|| ||.||.|||.||||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKEEISYG--------------------------------------------------ATTRTFCG--TPEYLAPEVLEDNDYGRAVDWWG--LGVVMY
|||| ...|                                                  ..| ||||  ||||.|||.|    ||.|.|||.  ||..||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMMCGRLPFYSR----------DHEVLFELIL------VEEVKFP----------SRLSTLAKDLLDRLLTKAPERRLGGGPD-----GVEEVKAHPFF
||..|. |||.           ... .|..|.       ..||||          . .|  ||||. .||.| ||.||| |..     |.||.|.||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase AqueK002.AA SGK 152-409 47 3.5e-150 467.27 In-house 1-283 (283) Show / Hide
Range on Protein: 152-409
Range on HMM: 1-283/283
Sequence Identity: 47% (136 aa)

FEMLKVLGKGTFGKVVLCREKST------------------DEIFAMKILKKDVIV-------AKDEITHTLTEN-RVLQSTKHPFLTQLKYSFQTADRL
|. |||.||| |||| . . |..                  | ..|||.|.|. |.       .| |  |...|   .|.  ||||. .|.|.|||.. |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

CFVMEYVNGGELFFHLSVEKMLTEERTRFYGAEITLAIGYLHSLGVVYRDLKLENLLLDRDGHIKLTDFGLCKEEISYGATTRTFCGTPEYLAPEVLEDN
 |||.||||||.|.||  || . | | ||| ||| .|..||||. ..||||| ||.||| .||..|||||||||.|    || ||||||||||||||   
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

DYGRAVDWWGLGVVMYEMMCGRLPFYSRDHEVLFELILVEEVKFPSRLSTLAKDLLDRLLTKAPERRLGGGPDGVEEVKAHPFF
 ..|.|||| || |.|||| |  |||||... ... |. .. ..|   |  |.||.  ||.| |. |||   .. .|.| ||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF

Kinase AqueK002.AA PKC 152-409 53 4.3e-144 470.06 In-house 1-262 (262) Show / Hide
Range on Protein: 152-409
Range on HMM: 1-262/262
Sequence Identity: 53% (139 aa)

FEMLKVLGKGTFGKVVLCREKSTDEIFAMKILKKDVIVAKDEITHTLTENRVL-QSTKHPFLTQLKYSFQTADRLCFVMEYVNGGELFFHLSVEKMLTEE
|..||||||| ||||.| . | |||..|.|.||||||.  | .  |.|| ||| ...||||||.|  .||| ||| ||||||||| | ||    . . ||
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RTRFYGAEITLAIGYLHSLGVVYRDLKLENLLLDRDGHIKLTDFGLCKEEISYGATTRTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF
..|||.|||..|  .||. |..||||||.| |||..||||..|||.|||.. .|.||.||||||.|.|||.|.  .|| .|||| .|| |||||.|. ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YSRDHEVLFELILVEEVKFPSRLSTLAKDLLDRLLTKAPERRLGGGPDG---VEEVKAHPFF
   | . ||. |. ... .|  ||  |....  ..|| ||.||| .|..    .....||||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF

Kinase AqueK002.AA RSK 155-409 44 3.1e-127 428.99 In-house 1-278 (278) Show / Hide
Range on Protein: 155-409
Range on HMM: 1-278/278
Sequence Identity: 44% (124 aa)

LKVLGKGTFGKVVLCREK---STDEIFAMKILKKDVIVAKDE-ITHTLTENRVLQSTK-HPFLTQLKYSFQTADRLCFVMEYVNGGELFFHLSVEKM---
|||||.| .||| |||..    |. |.|||.||| .||...  . ||.|| ..|. .. |||. .|.|.||| . |  .|||..||||| ||. ||.   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LTEERTRFYGAEITLAIGYLHSLGVVYRDLKLENLLLDR---DGHIKLTDFGLCKE-EISYGATTRTFCGTPEYLAPEVLE----DNDYGRAVDWWGLGV
..|.. .|| |||.||. .||..|...||||.|| |.|    .|||||||||.||.  ....  | |||.| ||.|||.|     .. ...|.||| |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

VMYEMMCGRLPFYS---RDHEVLFELILVEE--VKFP--SRLSTLAKDLLDRLLTKAPERRLGGGPDGVEEVKAHPFF
.||||  |..||..    ....... |.  .  ...|  . ||. ||||. ..|.. |..|||.||...||.|.||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase AqueK002.AA Eta 152-409 54 1.5e-121 410.13 In-house 1-261 (261) Show / Hide
Range on Protein: 152-409
Range on HMM: 1-261/261
Sequence Identity: 54% (141 aa)

FEMLKVLGKGTFGKVVLCREKSTDEIFAMKILKKDVIVAKDEITHTLTENRVLQ-STKHPFLTQLKYSFQTADRLCFVMEYVNGGELFFHLSVEKMLTEE
|. .|||||| ||||.| . | |||..|.|.||||||.  |..  |.|| |.|    ||||||||  .||| ||| |||||||||.| |..   .   | 
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP

RTRFYGAEITLAIGYLHSLGVVYRDLKLENLLLDRDGHIKLTDFGLCKEEISYGATTRTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF
|.||| ||.|.|. .||  ||.||||||.|.|||..|| || |||.||| |  | || ||||||.|.|||.|.. .|| .|||| .||.|||||||. ||
RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF

YSRDHEVLFELILVEEVKFPSRLSTLAKDLLDRLLTKAPERRLGGGP--DGVEEVKAHPFF
     . ||| || ..| .|  |.  |  .|   .|| |..|||     .| .....||||
EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF

Kinase AqueK002.AA Alpha 152-409 51 1.6e-118 400.09 In-house 1-259 (259) Show / Hide
Range on Protein: 152-409
Range on HMM: 1-259/259
Sequence Identity: 51% (133 aa)

FEMLKVLGKGTFGKVVLCREKSTDEIFAMKILKKDVIVAKDEITHTLTENRVLQ-STKHPFLTQLKYSFQTADRLCFVMEYVNGGELFFHLSVEKMLTEE
|  |.||||| |||| |   | ||| .| ||||||||.  | .  |..| |||  . | |||.|.   ||| ||| ||||||||| | .|.       | 
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFKEP

RTRFYGAEITLAIGYLHSLGVVYRDLKLENLLLDRDGHIKLTDFGLCKEEISYGATTRTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF
   || |||  .  .||. |..|||||| | .||..||||..|||.|||..  ..|||||||||.|.|||.   . ||..||||  || .|||| |  ||
HAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQPPF

YSRDHEVLFELILVEEVKFPSRLSTLAKDLLDRLLTKAPERRLGGGPDGVEEVKAHPFF
   | . ||. |   .| .|  .|  |.|.   .||| | .||| |||| .....||||
DGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGEQDIREHPFF

Kinase AqueK002.AA AktR 152-409 44 3.7e-118 398.85 In-house 1-268 (268) Show / Hide
Range on Protein: 152-409
Range on HMM: 1-268/268
Sequence Identity: 44% (120 aa)

FEMLKVLGKGTFGKVVLCREK-STDEIFAMKILKKDVIVAKDEITHTLTENRVLQ-STKHPFLTQLKYSFQTADRLCFVMEYVNGGELFFHLSVEKMLTE
|. .|.||||.||||.|...|  .....|||..||  |. .  . ||.||  ...   .|||. .|.|.||| . | |.|||. |||||.||. .| ..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

ERTRFYGAEITLAIGYLHSL-GVVYRDLKLENLLLDRDGHIKLTDFGLCK-EEIS-YGATTRTFCGTPEYLAPEVLED-NDYGRAVDWWGLGVVMYEMMC
|..||| |.| ||. |||.   ..||||| ||.||| |||.|.||||| | . .  |  ....|||||||.|||..     ....|||| .|.. |||. 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GRLPFYSRDHEVLFELILVEE---VKFPSRLSTLAKDLLD-RLLTKAPERRLGGGPDGVEEVKAHPFF
|  |||. ... .|..|. ..   ...|| .|  .|||.  .|| | |. ||| .  | ||.| ||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase AqueK002.AA PKA 152-409 42 2.2e-113 382.98 In-house 1-263 (263) Show / Hide
Range on Protein: 152-409
Range on HMM: 1-263/263
Sequence Identity: 42% (114 aa)

FEMLKVLGKGTFGKVVLCREKSTDEIFAMKILKKDVIVAKDEITHTLTENRVLQSTKHPFLT-QLKYSFQTADRLCFVMEYVNGGELFFHLSVEKMLTEE
|| ...||.|.||.| |||.|.. ...|||.|||. ||    . |...|...||..||||.  .....||... | .|||||.|||.| .|  .. ... 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

RTRFYGA-EITLAIGYLHSLGVVYRDLKLENLLLDRDGHIKLTDFGLCKEEISYGATTRTFCGTPEYLAPEVLEDN-DYGRAVDWWGLGVVMYEMMCGRL
 ..|| | .|.||. ||||.  .||||| ||.|.|..||||.||||  |.  .    | | ||||||||||..     .|..|||| ||.. |||. |  
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP

PFYSR--DHEVLFELILVEEVKFPSRLSTLA---KDLLDRLLTKAPERRLGGGPDGVEEVKAHPFF
|||    |   ..| |.  ..|||. ..  |   |||...||.. ...|.|   .||. .| |..|
PFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF

Kinase AqueK002.AA Delta 152-409 45 6.4e-110 371.48 In-house 1-259 (259) Show / Hide
Range on Protein: 152-409
Range on HMM: 1-259/259
Sequence Identity: 45% (120 aa)

FEMLKVLGKGTFGKVVLCREKSTDEIFAMKILKKDVIVAKDEITHTLTENRVLQ-STKHPFLTQLKYSFQTADRLCFVMEYVNGGELFFHLSVEKMLTEE
| ..|||||| ||||.|   | ... .|.| |||||..  |..  |. | |||  ...||||..|  .||| . | |||||.|||.| .|.   .   |.
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

RTRFYGAEITLAIGYLHSLGVVYRDLKLENLLLDRDGHIKLTDFGLCKEEISYGATTRTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF
|.|||..|| ... .||. |..||||||.|.|||.|||||. |||.|||..   ... ||||||.|.|||... . | ..||||  ||.||||. |  ||
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF

YSRDHEVLFELILVEEVKFPSRLSTLAKDLLDRLLTKAPERRLGG--GPDGVEEVKAHPFF
  .| . ||. |....  .|  ..  |||.| .|. . ||.|||    |.|  ....|.||
HGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKG--DIRQHCFF

Kinase AqueK002.AA S_TKc 152-409 37 4.7e-109 369.53 SMART 1-231 (231) Show / Hide
Range on Protein: 152-409
Range on HMM: 1-231/231
Sequence Identity: 37% (102 aa)

FEMLKVLGKGTFGKVVLCREKSTDEIFAMKILKKDVIVAKDEITHTLTENRVLQSTKHPFLTQLKYSFQTADRLCFVMEYVNG--GELFFHLSVEKM---
.|.|...|||.|||| .||.|.|..|.|.||.|           |.. | ..|.. .||.. .|...||. |.|..||||..|  |.|| ..   .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEERTRFYGAEITLAIGYLHSLGVVYRDLKLENLLLDRDGHIKLTDFGLCKEEISYGATTRTFCGTPEYLAPEVLEDNDYGR-AVDWWGLGVVMYE
   ..| ..||| ..| .|. |.||.|...|||| ||.|||.  |||..||||...        .||||||.|.|||||    ||. ..||| .|...||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MMCGRLPFYSRDHEVLFELILVEEVKFPSRLSTLAKDLLDRLLTKAPERRLGGGPDGV--EEVKAHPFF
|.||. ||.  .....|..|.          |  |||.....|.| ||.|..        ...|.||.|
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK002.AA Pkinase 152-409 31 6.5e-102 349.67 Pfam 1-293 (293) Show / Hide
Range on Protein: 152-409
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

FEMLKVLGKGTFGKVVLCREKSTDEIFAMKILKKDVIVAKDEITHTL-TENRVLQSTKHPFLTQLKYSFQTADRLCFVMEYVNGG----ELFFHLS--VE
.. ....|.|.||.| .|..|.| .|.|.||.||. .  . ..||.. .| ..... .||.  .|...|.. |....||||..||    .|| ..|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KML--TEERTRFYGAEITLAIGYLHSLGVVYRDLKLENLLLDRDGHI----KLTDFGLCKE--EISYGATTRTFCGTPEYLAPEVLE-DNDYGRAVDWWG
. .  .|.  .||  .|  .. |.|| |...||||.||.|.|..|||    |..||||.|   . ...  . ||||||.|.||||.  ...||..||.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVVMYEMMCGRLPFYSR------DHEVLFELILVEEVKFPSRLS---------------------TLAKDLLDRLLTKAPERRLGGGPDGVEEVKAHPF
.|...|||.|||.||...      |. .....|.  ...|..  .                       .||.....|.| |..|..      |... ||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPW

F
|
F

Kinase AqueK002.AA S_TK_X 410-474 35 3.2e-17 64.47 SMART 1-79 (79) Show / Hide
Range on Protein: 410-474
Range on HMM: 1-79/79
Sequence Identity: 35% (28 aa)

SVINWDDLYN--KKITPSFVPNIK----SEIDTKYFAPEFTGEEPKLTPPDADDPDAGVGN---------LHFQDFSFVP
. |.||.|||  |.|.| |.|.||    |..||..| |||| |.|.   || . . .....         ..| .|..| 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

Kinase AqueK002.AA Pkinase_Tyr 152-362 23 2.7e-15 52.43 Pfam 1-228 (270) Show / Hide
Range on Protein: 152-362
Range on HMM: 1-228/270
Sequence Identity: 23% (55 aa)

FEMLKVLGKGTFGKVVLCREK----STDEIFAMKILKKDVIVAKDE--ITHTLTENRVLQST-KHPFLTQLKYSFQ-TADR--LCFVMEYVNGGELFFHL
 ...|.||.| ||.|.... |    .|.   | |.||      ...  .   . | ... .  .|| . .|        .   .. ||||. .| |  .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

SV----EKMLTEERTRFYGAEITLAIGYLHSLGVVYRDLKLENLLLDRDGHIKLTDFGLCKEEIS---Y-GATTRTFCGTPEYLAPEVLEDNDYGRAVDW
      .. || ..   . ..|  .  ||.| . . |||   | |.......| .||||..   .   |  ... .       .|||.. .. .  . | 
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDV

WGLGVVMYEMMC-GRLP-FYSRDHEVLFELI
|  ||.|.|..  |. | ..  . | ..|.|
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI

Kinase AqueK002.AA TyrKc 152-403 20 2.7e-14 8.42 SMART 1-280 (280) Show / Hide
Range on Protein: 152-403
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

FEMLKVLGKGTFGKVVLCREKSTDEIFAMKILKKDVIVAKDEITHTLTENRVLQST--KHPFLTQLKYSFQTA-------DRLCFVMEYVNGGELFFHLS
 ...|.|| | ||.|.... |   .  | | ||.|    . ..   . | |.. .   .|| . .|     .        . |. ||||. .| |  .| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDF---MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

VEKM-LTEERTRFYGAEITLAIGYLHSLGVVYRDLKLENLLLDRDGHIKLTDFGLCKEEISY---GATTRTFC-----GTPE-----YLAPEVLEDNDYG
  .  |. .    .   |     |||| ... |||   | |.......| .||||...  ..   |. . .       |.        .|||.. .. . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

RAVDWWGLGVVMYEMM-CGRLPFYS-----RDHEVLFELILVEEVKFPSRL----------STLAKDLLDRLLTKAPERR-----LGGGPDGVEEV
 . | |  ||.|.|..  |  | .       . . ..|..   .   .             . . . .  .     || |     .      .|. 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI------HECF

Kinase AqueK002.AA Pkinase_C 429-476 39 6.8e-12 45.12 Pfam 1-46 (46) Show / Hide
Range on Protein: 429-476
Range on HMM: 1-46/46
Sequence Identity: 39% (19 aa)

NIKSEIDTKYFAPEFTGEEPKLTPPDADDPDAGVGNLHFQDFSFVPEA
..||..|| .| |||| | |..|||| .   .|  . .|..|..|.. 
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQE-PFRGFTYVNPD