Gene n1201 (Tetrahymena)

n1201

Species: Tetrahymena
Alias: 90.m00164, 1201, 90.m00163, n1201
External Links:
Annotation:

Classification

Group: Other
Family: Ciliate-C7

Sequence

Name Sequence Type Origin Length Description Download
n1201.AA Protein None 495 None Fasta, JSON
n1201.NA RNA None 1484 None Fasta, JSON
n1201.kin_dom Protein Kinase Domain None 170 None Fasta, JSON

Protein domain

Protein domains of n1201.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase n1201.AA Ciliate-C7 78-233 76 2e-112 361.63 In-house 1-164 (164) Show / Hide 
Range on Protein: 78-233
Range on HMM: 1-164/164
Sequence Identity: 76% (126 aa)

FRFLGQGVQGFVLLAKNSYTNMRYAIKGVQVRDPQGNIDEDLNNRVKQEVEILKKCRDSPYVVSLLDQFEGQQFSYLVLTECQ--------ERNQIIRLN
||||||| || |||||.. ||||||||||||||.|||||.|.||.|.||..|||.|.||||||.||.|||||||.||||.|||        ||||  |||
FRFLGQGQQGLVLLAKDQKTNMRYAIKGVQVRDKQGNIDQDINNQVQQEINILKQCKDSPYVVCLLHQFEGQQFIYLVLNECQGGTLNQIIERNQNKRLN

EISVIKYAHDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNAVVSDFGLADNLINKSGYAFNQYM
||| ||||.||||||||||||||.|||||||||||||.|||||.||||||||..||.|..||||
EISAIKYAKDIAQGLYYIHSKNCVVNDLKMDNILIDYNGNAVVCDFGLADNLTQKSKYQINQYM
Kinase n1201.AA CAMK 80-242 16 2.4e-22 68.2 In-house 1-290 (425) Show / Hide 
Range on Protein: 80-242
Range on HMM: 1-290/425
Sequence Identity: 16% (49 aa)

FLGQGVQGFVLLAKNSYTN------------MRYAIKGVQVRDPQGNI----------------------DEDLNNRVKQEVEILKKCR------DSPYV
 ||.|  | | |...  |.             ..||| .  .  ...                       ..    .|..|.||.||..      | | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLLDQFEG-------------------QQFSYLVL--TECQERNQI--------------------------IRLNEISVIKYAHDIAQGLYYIHSKNC
..|.. .|                    ... |.|.  .|  .                               |..|  . .| . |.... |.||.| 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LVNDLKMDNILIDYH-----------------GNAVVSDFGLADNLINKS----------------------GYAFNQYMGNVLYQA-PE
   ||| .|||.|..                 .|  ..|||.|  .. ..                      |  .. . |   | | ||
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPE
Pkinase n1201.AA Pkinase 75-218 28 3.3e-21 76.08 Pfam 1-159 (293) Show / Hide 
Range on Protein: 75-218
Range on HMM: 1-159/293
Sequence Identity: 28% (46 aa)

YSEFRFLGQGVQGFVLLAKNSYTNMRYAIKGVQVRDPQGNIDEDLNNRVKQEVEILKKCRDSPYVVSLLDQFEGQQFSYLVLTECQE-----RNQ--II-
|   | .|.|  | | ....  |. ..|.| . .|.   . |. . ..  .|..|.|.. ..|..| |.| ||  .  |.|.  |.           |  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

----RL--NEISVIKYAHDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNA----VVSDFGLA
    ..   |  ...|.  |..||.|.||....  ||| .||||| .|.      ..|||||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase n1201.AA CAMKL 75-244 24 1.3e-20 62.35 In-house 1-205 (297) Show / Hide 
Range on Protein: 75-244
Range on HMM: 1-205/297
Sequence Identity: 24% (50 aa)

YSEFRFLGQGVQGFVLLAKN-SYTNMRYAIKGVQVR----DPQGNID------EDLNNRVKQEVEILKKCR--DSPYVVSLLDQFEGQQF------SYLV
|   . ||.|  | | ||.. ..|. ..||| .  .    ||. .        |.   |...|..|.|. .    | ...|.. .| ...       |||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LTECQERN----QII--R------LNEISVIKYAHDIAQGLYYIHSKNCLVNDLKMDNILIDYHG--NAVVSDFGLADNLI---NKSGYAFNQYMGNVLY
.  |.  .    . |  .      . |    .|   |  ...|.||..    |.| .|||.|..|  |. ..|||..   .   ...|  ..   |   |
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

QAPECI
.||| .
MAPEIF
Kinase n1201.AA Ciliate-E2 75-244 18 1.2e-18 60.6 In-house 1-259 (365) Show / Hide 
Range on Protein: 75-244
Range on HMM: 1-259/365
Sequence Identity: 18% (48 aa)

YSEFRFLGQGVQGFVLLAKNSYTNMRYAIK-------------GVQ-VRDPQGNIDEDLNNRVKQEVEILKKCR---------------DSPYVVSLLDQ
|   . .||| .| | ..|.  .. ..|||             .|.       .. ..  . .|||  |... .               ..|... . . 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--GQQFSYLVLTECQERN--QIIR---------------LNEISVIKYAHDIAQ---------------GLYYIHSKN-CLVNDLKMDNILIDYHGNA
|.   ..  |||.  ||  .  ..|.               ..|  ....   |.|               .| |.|||| ..  |.| .|||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

VVSDFGLADNLINKSGY------------------------------AFNQYMGNVLYQAPECI
 ..||||. .. ... .                               ||.. |.  |.||| .
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEIL
Kinase n1201.AA Ciliate-E1 81-244 19 1.4e-17 54.15 In-house 1-182 (202) Show / Hide 
Range on Protein: 81-244
Range on HMM: 1-182/202
Sequence Identity: 19% (36 aa)

LGQGVQGFVLLAKNSYTN-MRYAIKGVQVRDPQGNIDEDLNNRVKQEVEILKKCRDSPYVVSLLDQFEGQQ--FSYLVLTECQER-----N---------
.|.| ...|. ||.  .|   .|.| ..... .  ...  ..  |.. .|.|  .   |.. ..|... .|  ........|...     .         
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHF--QDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQ

----QIIRLNEISVIKYAHDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNAVVSDFGLADNLINKSGYAFNQYMGNVLYQAPECI
    . . ...  ... . .. .|| ..|..| .  |.|..||||.  || | .|||....|.|.. .  ..      |. ||..
QCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQY
Kinase n1201.AA Ciliate-E2-Unclassified 75-245 18 1.6e-16 53.83 In-house 1-239 (352) Show / Hide 
Range on Protein: 75-245
Range on HMM: 1-239/352
Sequence Identity: 18% (46 aa)

YSEFRFLGQGVQGFVLLAKNSYTNMRY------AIKGVQVRDPQGNIDEDLNNRVKQEVEILK---------------KCRDSPYVVSLLDQFEGQQFSY
|   . .||| .| | ..... ..  |        . .. .  . | | ...|  ..|....|               .  ..|..| ....|. .|  |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMN-EMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

LVLTECQ--ERNQIIR---------------------LNEISVI-----KYAHDIAQGLYYIHSKN-CLVNDLKMDNILIDYHG---NAVVSDFGLADNL
.|.  |.  .  |.|.                     . |  ..     .|.  | ||| |.|.|| ..  |.| .|||.|  |   .  ..|||.. ..
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

INKSGYAFNQY---------------MGNVLYQ----APECID
.. ...  ..                .|.  |.    |||...
QQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQ
Kinase n1201.AA S_TKc 75-331 19 3.1e-16 61.08 SMART 1-231 (231) Show / Hide 
Range on Protein: 75-331
Range on HMM: 1-231/231
Sequence Identity: 19% (57 aa)

YSEFRFLGQGVQGFVLLAKNSYTNMRYAIKGVQVRDPQGNIDEDLNNRVKQEVEILKKCRDSPYVVSLLDQFEGQQFSYLVLTECQE-----RNQIIR--
|   | .|.|  | | ....  |. ..||| .              .....|..||||  . |..| |.| |.  .. |.|.  |       .  | .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

-------LNEISVIKYAHDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNAVVSDFGLADNLINKSGYAFNQYMGNVLYQAPECIDPADP-----------
       ..|  . .|.. |...| |.||.. .  ||| .|||.|   .  ..|||||  |        . . |   | ||| . . ..           
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCI

----FIGKV-YHDEYLKLGVTVRQEPSNRGIDLNLLSNKHKPLNYDGELKNFVYHNQLKYIIEGLTNFVPKNRMPIKEALI-----ILKGII
    . |.  .. .. ..   ..                                 ..| .|... .. |..|. . |||       .   .
LYEMLCGYPPFP-QMQMMFKKIG-------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase n1201.AA Dicty4-Unclassified 161-218 44 5.2e-16 51.28 In-house 99-156 (263) Show / Hide 
Range on Protein: 161-218
Range on HMM: 99-156/263
Sequence Identity: 44% (26 aa)

ERNQIIRLNEISVIKYAHDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNAVVSDFGLA
|..| |.|..  .|||| |||||. . |..|    |.|  |||.| | |. . |||..
EQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGIS
Kinase n1201.AA SAK 75-221 29 1.9e-13 41.89 In-house 1-150 (254) Show / Hide 
Range on Protein: 75-221
Range on HMM: 1-150/254
Sequence Identity: 29% (45 aa)

YSEFRFLGQGVQGFVLLAKNSYTNMRYAIKGVQVRDPQGNIDEDLNNRVKQEVEILKKCRDSPYVVSLLDQFEGQQFSYLVLTECQE-------RNQIIR
|     ||.|    |  ||   | .  ||| .  .  |.     . .||..||||  . .  | .. |   || . . ||||  |.        ....  
YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKT---GMVQRVRNEVEIHCQLKH-PSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRP

LNEISVIKYAHDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNAVVSDFGLADNL
  |    .. |.|  |. |.|| . .  || . |||.    .  . |||||  |
FTEEEARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQL
Kinase n1201.AA TKL 174-254 20 2.4e-13 44.44 In-house 135-255 (364) Show / Hide 
Range on Protein: 174-254
Range on HMM: 135-255/364
Sequence Identity: 20% (25 aa)

IKYAHDIAQGLYYIHS--------KNCLVNDLKMDNILIDYHGN--------------AVVSDFGLADNLINKSGYAFNQY------------------M
.. |.|||.|..| ||        .. .  ||| .|||.| ...              . ..||||. .. ....   ...                   
CRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQC

GNVLYQAPECIDPADPFIGKV
|.  . |||... ....  ||
GTPRWMAPEVLRGQMNYTEKV
Kinase n1201.AA STE 75-144 18 1.5e-07 22.83 In-house 1-97 (359) Show / Hide 
Range on Protein: 75-144
Range on HMM: 1-97/359
Sequence Identity: 18% (18 aa)

YSEFRFLGQGVQGFVLLAKNSY---------------TNMRYAIKGVQVRDPQ-----------GNIDEDLNNRVKQEVEILKKCRD-SPYVVSLLD
.   ...|.|  | | .|.|                 |. ..||| . ... .            |....  .....|..|.|||.. .|..|  ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYG
Kinase n1201.AA STE 167-242 25 6.5e-07 20.59 In-house 147-232 (359) Show / Hide 
Range on Protein: 167-242
Range on HMM: 147-232/359
Sequence Identity: 25% (23 aa)

RLNEISVIKYAHDIAQG-LYYIHSKNCLVNDLKMDNILIDYHGNAVVSDFGLADNLIN---------------KSGYAFNQYMGNVLYQAPE
|..|  .......| .| |||.||..    |.| .|||.     .  .|||.. .|..                ..   |   |   . |||
RFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPE
Kinase n1201.AA TyrKc 75-327 17 2e-06 -118.31 SMART 1-280 (280) Show / Hide 
Range on Protein: 75-327
Range on HMM: 1-280/280
Sequence Identity: 17% (56 aa)

YSEFRFLGQGVQGFVLLAKNSYTNMRYAIKGVQVRDPQGNIDEDLNNRVKQEVEILKKC-RDSPYVVSLLDQFEGQQ------FSYLVLTE------CQE
 .  . || |  | | ... .   .  |.| ..                 .| .|..|   . | .| |.     |.        .....|      ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

RNQIIR--LNEISVIKYAHDIAQGLYYIHSKNCLVNDLKMDNILIDYHGNAVVSDFGLADNLINK------SGYAFNQY--MGN----VLYQAPECI---
. .  |  |.    ......||.|  |.|||||   ||   |.|..  . . .|||||. .. ..      . |   .    |.    .   |||||   
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

--------------------DPADPFIG-----KVYHD--EYLKLGVTVRQEPS----NRGIDLNLLSNKHKPLNYDGELKNFVY-HNQLKYIIEGLTNF
                    . . |  |     .   .  ||.| |   .| |.                            ||  .  .  |..   ..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------------FVCCPDEMYQIMKQCWHE

VPKNRMPIKEALIIL
 |..|   .|   ..
DPEDRPTFSEIHECF