Gene 38246 (M.brevicollis)

38246

Species: M.brevicollis
Alias: 38246
External Links:
Annotation:

Classification

Group: TK-assoc
Family: PTP
Subfamily: HD-PTP

Sequence

Name Sequence Type Origin Length Description Download
38246.AA Protein None 1568 None Fasta, JSON

Protein domain

Protein domains of 38246.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
BRO1 38246.AA BRO1 52-427 23 4.6e-52 178.84 Pfam 1-420 (420) Show / Hide 
Range on Protein: 52-427
Range on HMM: 1-420/420
Sequence Identity: 23% (98 aa)

RFLAASVKTAQPCAIEDTLIKFISQTL-EQPGED---YRVELQQLRNLRATLHTG--HVDQQYLANARLYAAQLHFAKSRF--YAGSTTPQ--LDFSWLD
 ...   | . ..   . | ..|. .  .|. .    |. ....|..|| .. .   ..... | .   |..||..  .||    .    .  ..|.| |
PMIWIPLKKTKEVDWTKPLKNYIKNHYSGQDPWMQFYYEDDCAELNQLRQDARNPCPSPHESGLELLYRYYGQLCWLEKRFFPPFH-DDRHIGVEFTWYD

TF----TKS-----FVSSHALAHEYGSVLFNIAGAAGRLASLE--FAGADSSDDTLKTCLQMQQLSVAAI---MAVQQQ---ELGDTPSH-DMHAAALDV
.|    ..|      |....|| |  .|||||.    ..|. .    .  ..|. ||.  .. | .  .      . ..   |.  .||  ||... | .
AFDHRSHGSSFGRRPVCQNNLAFEKACVLFNIGALYSQIAASQYES-DNRDTDEGLKQACHYFQQAAGCFDCAQYLNENVPAEFLHAPSVYDMSPETLKC

LLHVYTAQSYQCSLYKALH---S-NMKATTIARIAIRVANEFDAAHKALYSIETNKD-HPWHLWQLCVQLKSMHARGLAQFYQGQAA--NKASEWGEEV-
| .   ||   | . ||..     .||.. ||..|  |.. .. .|.|. . .....  ||  |   ||.|..| ...|..|.....  . ... ||.. 
LVNLMLAQAQECFWQKAINQDIDMGMKDSLIAKLAAQVSDYYQECHRAMQKSPYKCYYWPWKEWIHHVQCKQHHFKAVAHYYHALHCCDEEKKKYGEAID

--GRLRAARDVLQAAIETAKA-VKNAVDVAAIQHTLNLVTERLTKAETDNNTIFHETVPSDAALSEIVAADLFAFKPFEPDP--------SAVDILHRLM
  ..|..| . |. |. ..|.  .|  .. ... . . ..| |..|| ||. |.|| ||. . |..| ..|.    |..              |. ..| 
LKAHLQHAQQCLKEAQKKHKKCYVNY-LQDDLKYLHDRIQEKLKRAEKDNDFIYHEPVPDEVSLPPIKPMDMVKPIPWNEVFEPQEATKHKCPDLFKKLV

PLDVHLAISTFSEQKATLVRNVA
|..|| | | .|| |...||| .
PMAVHEAASIYSERKDKYVRNEI
PTPc 38246.AA PTPc 845-1152 31 1.6e-95 324.54 SMART 1-308 (308) Show / Hide 
Range on Protein: 845-1152
Range on HMM: 1-308/308
Sequence Identity: 31% (109 aa)

GFDKEFALLEMEDAAH-------NRDTSCAAAERNV--DRNRYR-DILPYDRTRVHMQVLPGY---GSTDDYINACHVRSLTSGCPDFVCAQGPKHSTSG
|| .||  |....          .....||. . |.  |.|||. ||..||.|||. . .||.    . .||||| ....   .   . |.|||. .|  
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY-WRPKRYICTQGPLPHTIE

DFWKMVVQQRSRVIVMVTNLEER--------GRPKCDRYWPARCGETVSHPETALGLALDVTLKEERETG-PWIERDLIVETLRPD-----HTKMVRHVK
|||.|| ||....||| .|..|.        || ||..|||          .   |  . ||.|.|  .   .. |.. |.   ..      .. .| |.
DFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--------PMTYG-HITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVT

QFHYTSWPDHGVPASPETFLEFLLAVKQHHDAVQRQSQ---------TAGEPQSPLVVHCSAGVGRTGTFCCVYGVVAALPYVGNGLPLLAARESGAQRP
..|||.||||||| ||. ||.|. .|....   . ..          .. .|..| |||||||.|||||||..  ..  .                    
HYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN------------------

TRESQGGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLEAAR
        .|| .||..||. | .|||| .||.||| . || ..
--------VDIFQIVKMMRNQRPGMVQTEEQYIFCYRCILEYIK
Y_phosphatase 38246.AA Y_phosphatase 872-1149 35 9e-86 296.05 Pfam 1-243 (243) Show / Hide 
Range on Protein: 872-1149
Range on HMM: 1-243/243
Sequence Identity: 35% (101 aa)

NVDRNRYRDILPYDRTRVHMQVLPGYGSTDDYINACHVRSLTSGCPDFVCAQGPKHSTSGDFWKMVVQQRSRVIVMVTNLEERGR-PK-CDRYWPA-RCG
| ..|||.||..||.|||..| . . .  .||||| ....    .  . |.|||...| .|||.|| ||....|||..|..|.||  | |..|||   .|
NKEKNRYKDIPCYDHTRVKLQPI-PGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEG

ETVSHPETALGLALDVTLKEERETGPWIERDLIVETLRPDHTKM----VRHVKQFHYTSWPDHGVPAS-PETFLEFLLAVKQHHDAVQRQSQTAGEPQSP
.....        . ||...| .     . | .|.|..  . .     .| |...|||.||||||| | |  .|.|.  |....      .. .|   .|
QPMTYG------DFQVTCVSEEH-----CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP-----NPDHGC--PP

LVVHCSAGVGRTGTFCCVYGVVAALPYVGNGLPLLAARESGAQRPTRESQGGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLE
 |||||||.|||||||..                        |. ..|      ||..||..||. | .|||| .||.||| . ||
IVVHCSAGCGRTGTFCAID--------------------IMCQQMEHEGTV---DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
PTPc_motif 38246.AA PTPc_motif 1015-1149 33 3.8e-39 137.3 SMART 1-92 (92) Show / Hide 
Range on Protein: 1015-1149
Range on HMM: 1-92/92
Sequence Identity: 33% (47 aa)

HVKQFHYTSWPDH-----GVPASPETFLEFLLAVKQHHDAVQRQSQTAGEPQSPLVVHCSAGVGRTGTFCCVYGVVAALPYVGNGLPLLAARESGAQRPT
 |...|||.||||     |||   . .|||. .|..                 |.|||||||.|||||||... ..                        
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-----------------PIVVHCSAGCGRTGTFCAIDMMMQQ----------------------

RESQGGKLDIMNIVSRMREDRRFMVQTVDQYKFCYLASLE
       .|| ..| .||. |..|||| .||.||| . ||
-------VDIFQTVKEMRKQRPGMVQTEEQYIFCYRCILE