Gene 25438 (M.brevicollis)

25438

Species: M.brevicollis
Alias: 25438
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Crk

Sequence

Name Sequence Type Origin Length Description Download
25438.AA Protein None 428 None Fasta, JSON

Protein domain

Protein domains of 25438.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 25438.AA SH2 6-87 45 1.9e-31 111.71 SMART 1-87 (87) Show / Hide 
Range on Protein: 6-87
Range on HMM: 1-87/87
Sequence Identity: 45% (40 aa)

APWYHGPLSRTDAENSLLR--MPEGTFLVRDSTSSPGDYVLSCSENGKVTHYKLSAEE-GKIRIDT---HLFDNLDAAITFYMEHELE
 |||||..|| .||. |..  ||.|.|||||| |.|||||||.  .||| ||..  .. || .||.   . |..|   . .|. . | 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 25438.AA SH2 8-81 39 1.1e-30 91.87 Pfam 1-81 (81) Show / Hide 
Range on Protein: 8-81
Range on HMM: 1-81/81
Sequence Identity: 39% (32 aa)

WYHGPLSRTDAENSLLR--MPEGTFLVRDSTSSPGDYVLSCSENG---KVTHYKLSAEEGK--IRIDTHLFDNLDAAITFY
||||..|| .||. |.   .|.||||||.| |.||||.||   .|   .|.||.   ....   ... | |..|   . .|
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH3 25438.AA SH3 112-169 31 2.3e-16 61.64 SMART 1-58 (58) Show / Hide 
Range on Protein: 112-169
Range on HMM: 1-58/58
Sequence Identity: 31% (18 aa)

FSAEGLYKFVGRNENDLPFDKGELLNVLQLTQDNWWMAQSQKTLKIGYVPVNYVRALE
. .  || . ..|...|.| ||. . ||. . |.|| .. ..| ..|..| |||. ..
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 25438.AA SH3_1 115-162 26 1.1e-12 45.83 Pfam 1-49 (49) Show / Hide 
Range on Protein: 115-162
Range on HMM: 1-49/49
Sequence Identity: 26% (13 aa)

EGLYKFVGRNENDLPFDKGELLNVLQLTQD-NWWMAQSQKTLKIGYVPV
  || ........|.| ||. . |.. . | .|| .... | . |..|.
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 25438.AA SH3_2 119-168 22 0.000643 16.61 Pfam 7-68 (68) Show / Hide 
Range on Protein: 119-168
Range on HMM: 7-68/68
Sequence Identity: 22% (14 aa)

KFVG-RNEND-----LPFDKGELLNVL---QLTQDNWWMA-QSQKTLKI--GYVPVNYVRAL
..|. ...|.     | | ||... |.      .|||| .  . .. .   |..| ..|. .
DYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH3 25438.AA SH3 346-405 30 0.001761 10.14 SMART 1-58 (58) Show / Hide 
Range on Protein: 346-405
Range on HMM: 1-58/58
Sequence Identity: 30% (18 aa)

TLVRAITAIIPNAYDNDALVLEENDLVHVLDGGEGALERGRVLRTGQIGLYPFAKTEDIE
  |||. .  .   . | | ....| ..||.  ..   .||. ||||.|. |    | |.
PYVRALYDYQA--QNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_2 25438.AA SH3_2 347-395 15 0.338888 7.08 Pfam 1-59 (68) Show / Hide 
Range on Protein: 347-395
Range on HMM: 1-59/68
Sequence Identity: 15% (9 aa)

LVRAITAIIPNAYDNDA-----LVLEENDLVHVL---DGGEGALERG-RVLRTGQI--GL
..|..  ..| |....      | ....|...|.   |   .   .. ... .|.   |.
YYRVHCDYVP-ATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGW
SH3_1 25438.AA SH3_1 384-398 46 37.136221 0.43 Pfam 35-49 (49) Show / Hide 
Range on Protein: 384-398
Range on HMM: 35-49/49
Sequence Identity: 46% (7 aa)

RGRVLRTGQIGLYPF
.||...||| |. | 
KGRCNNTGQEGWFPS