Gene ULK1 (Sea Urchin)

ULK1

Species: Sea Urchin
Alias: Spk199, ULK1, SPU_027245
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
ULK1.AA Protein None 960 None Fasta, JSON
ULK1.kin_dom Protein Kinase Domain None 264 None Fasta, JSON

Protein domain

Protein domains of ULK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ULK1.AA ULK 9-272 31 5.3e-126 424.9 In-house 1-324 (324) Show / Hide 
Range on Protein: 9-272
Range on HMM: 1-324/324
Sequence Identity: 31% (103 aa)

YNKKDIIGHGAFA-IVFRGR-ERKRP-DQTVAIKCINKKNLSKSQT---------FPEKEIEILKELH---HGN--VVSLLHFKETT--SSLFMVMEFCN
|......|.|.|.  |..|| ...   .| ||.|.|.||...|..          . ..||.|.|.|.   | |  .| |....||.    ....||.||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLADYLHIKGTLSEDT----------IRFFLGQIACAMKAIHEKGIIHRDLKPQNLLLSHNSKHK----VPHPNEIHLKIADFGFARFLEGDMMAATL
|||| .|.. ...|.| |          .. |. ||. ..|..|...|||||.||||.|....  ..    | || ...|||||||||.... ..|....
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFAKHVDNNNMEQQM

C----------GSPLYMAPEVITSQ-----HYDAKADLWSIGTIIFQCLTGSAPFKAANPPELK-------------KLYMKARTLDPNIPP---GTSKA
|          |.||||||... .|     .||.|.|.||.|.|....|.|. ||..  . ...             ..|.| . .....||     |. 
CQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPE

LKDLLIRLLKRNQKDRIEFDKFFSHDFL
.|||. |.|....||||... .|.| ..
CKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase ULK1.AA ULK 9-272 31 3e-120 405.79 In-house 1-329 (329) Show / Hide 
Range on Protein: 9-272
Range on HMM: 1-329/329
Sequence Identity: 31% (106 aa)

YNKKDIIGHGAFAIVFRGRERKRP---DQTVAIKCINKKNLSKSQTF---------PEKEIEILKELH--------HGNVVSLLHFKETT--SSLFMVME
|......|.|.|. |..||  |.    .. ||.| | |. .....            ..||.|.|.|.        | |.| |....||.    ....||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCNGGDLADYLHIKGTLSEDT----------IRFFLGQIACAMKAIHEKGIIHRDLKPQNLLLSHNSKHK----VPHPNEIHLKIADFGFARFLEGD---
.|||||| .|.. ...|.|||          .. |. ||. ..|..|...|||||.|||| |.. .  ..    | || ...|||||||||.... |   
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFAKHVDNDNME

---MMAAT----LCGSPLYMAPEVITSQ-----HYDAKADLWSIGTIIFQCLTGSAPFKAANPPELK-KLYMKARTLDPNIP----------------PG
   ||...    |||.||||||... .|     .||.|.|.||.|.|....|.|  ||.|  . ... . ..| . . |..|                | 
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ

TSKALKDLLIRLLKRNQKDRIEFDKFFSHDFL
 |. .|||. |.|....||||... .|.| ..
ISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase ULK1.AA AGC 9-272 19 1e-95 247.26 In-house 1-395 (395) Show / Hide 
Range on Protein: 9-272
Range on HMM: 1-395/395
Sequence Identity: 19% (81 aa)

YNKKDIIGHGAFAIVFRGRERKRP-----DQTVAIKCINKKN---------LSKSQTF--------PEKEIEILKELH----------HGNVVS-LLHFK
.. . .|| |.|  |.  |.....     ..  |.|...||          . . .|           .| .||....          | ..|. | .  
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETTSS--LFMVMEFCN---------GG-DLADYLH---IKGTLSEDTIRFFLGQ-------IACAMKAIHE-KGIIHRD-LKPQNLLLSHNSKHKVPHPN
.. .   |..|||...         || .|  .|.    .|...|...||.. .       |..|.  .|. .|||||| ||| |.|| ..         
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED---------

EIHLKIADFGFARFLEGDM---------------------------------------------------MAATLCG--SPLYMAPEVITSQHYDAKADL
  |.|..|||..  . .|.                                                   .. |.||  .| |||||..    |.  .| 
-GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDW

WS--IGTIIFQCLTGSAPFKAANPP-------ELKKLYMKAR------TLDPNIP----------PGTSKALKDLLIRLLKRNQKDRIE----------F
||   | .... |||  || . ||          .... | .      . .. .|          .  |. .|||. .||... ..|.           .
WSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGA

DKFFSHDFL
.   .| . 
EEIKNHPWF
Kinase ULK1.AA S_TKc 9-272 33 3.9e-94 319.95 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-272
Range on HMM: 1-231/231
Sequence Identity: 33% (94 aa)

YNKKDIIGHGAFAIVFRGRERKRPDQTVAIKCINKKNLSKSQTFPEKEIEILKELHHGNVVSLLHFKETTSSLFMVMEFCNG--GDLADYLHIKGT----
| . ..||.|||. |...|..|  .. ||||.|.           ..||.|||. || |.| |. . .. ..|.||||.|.|  ||| ||.. .|.    
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSEDTIRFFLGQIACAMKAIHEKGIIHRDLKPQNLLLSHNSKHKVPHPNEIHLKIADFGFARFLEGDMMAATLCGSPLYMAPEVITSQHYDA-KADLW
  ..| ..||.. ||.||.. .|..|||||||||.|.||..            |.||.|||.||.|       |.||.| ||||||.   .|.  |.| |
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWW

SIGTIIFQCLTGSAPFKAANPPELKKLYMKARTLDPNIPPGTSKALKDLLIRLLKRNQKDRIEFDKFFS-------HDFL
|.| |.. .|.|  ||      ...... | .          |. .||.. ..|... ..|.   . .        | ..
SCGCILYEMLCGYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ULK1.AA CAMK 14-272 22 1.6e-83 268.88 In-house 1-425 (425) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-425/425
Sequence Identity: 22% (98 aa)

IIGHGAFAIVFRGRERKRPD-----------QTVAIKCINKKNLSK---------------------------SQTFPEKEIEILKE-------LHHGNV
..|.|.|..|....... .            | |||| |.|| |..                           .. . ..||||.|        |.| |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLLHFKE------------TTSS--------LFMVM---EFCNGG----DLADYLHIK---------------GTLSEDTIRFFLGQIACAMKAIHEKG
..|... |            | |         ..|||   |.| ||    || ||.  .               | ..|.  |..  ||..|.. .|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDLKPQNLLLSHNSKHKVPHPNEIH----------LKIADFGFARFLEG------------------------DMMAATLCGSPLYMA-PEVITS--
|.|||||| |.||..|.... | . | |          .||.|||||.....                        . .  | ||.| ||| |||. .  
IVHRDLKPENILLDDNNDDSDP-V-E-HDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG

------------QHYDAKADLWSIGTIIFQCLTGSAPFKAA-------------NPPELKKLYMKAR-TLDPNIPPGTS--------------------K
            . |. |.| ||.| | . .|.|  || .              |..||..  ||.. . .|   ...|                    .
HCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQ

ALKDLLIRLLKRNQKDRIEFDKFFSHDFL
  |||. ..|... ..|.  .   .| ..
ECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase ULK1.AA Pkinase 9-272 28 1.6e-81 281.93 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-272
Range on HMM: 1-293/293
Sequence Identity: 28% (87 aa)

YNKKDIIGHGAFAIVFRGRERKRPDQTVAIKCINKKNLSKSQ------TFPEKEIEILKELHHGNVVSLLHFKETTSSLFMVMEFCNGG----DLADYLH
| .. .|| |.|. |....... .. .||.|.|.|.. ....      .    ||.|.|.|.| |.| |... |. ... ||||.|.||    ||.||..
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

--IKGTL--SEDTIRFFLGQIACAMKAIHEKGIIHRDLKPQNLLLSHNSKHKVPHPNEIHLKIADFGFARF--LEGDMMAATLCGSPLYMAPEVIT-SQH
   .|..  ||....|.. ||..... .|..|||||||||.|.|...|   .       ..||.|||.|..  .  .  . |.||.| |||||||  .|.
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQY

YDAKADLWSIGTIIFQCLTGSAPFKAA----NPPELKKLYMKARTLDPNIPPGTS---------------------KALKDLLIRLLKRNQKDRIEFDKF
|. |.| ||.| |... |.|  ||. .    |  . .... . .  ..  .  ..                     ...||.. ..|... |.|. ..  
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

FSHDFL
. |...
LQHPWF
Kinase ULK1.AA CAMKL 9-272 28 7e-77 244.86 In-house 1-297 (297) Show / Hide 
Range on Protein: 9-272
Range on HMM: 1-297/297
Sequence Identity: 28% (88 aa)

YNKKDIIGHGAFAIVFRGRERKRPDQTVAIKCINKKNLSK----SQTFPE----------KEIEILKELH---HGNVVSLLHFKETTSS------LFMVM
|.  . .|.|.|. |  .. .. . . |||| |.|| ...    .. ..           .||.|.| |.   | |...|..  || .       ...||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFCNGGD--LADYLHIK----GTLSEDTIRFFLGQIACAMKAIHEKGIIHRDLKPQNLLLSHNSKHKVPHPNEIHLKIADFGFARFLE-G----DMMAAT
| | ||.  | ||.  .    | ..|.  |..  || .|.. .|..||.|||.|| |.||..| ..         .||.||||. . . .    . .  |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--------NIKIIDFGFSNMYRPCIFGPGQKLKT

LCGSPLYMAPEVITS--QHYD-AKADLWSIGTIIFQCLTGSAPFKAANPP-----ELKKLYMKART-LDPNIPPGTSKALKDLLIRLLKRNQKDRIEFDK
 |||| |||||.. .  ..||  |.| ||.| | .  ..|  ||.... .        .|| | ..   |.|..  |  ..||. ..|..| ..|.  . 
FCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCGYYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQ

FFSHDFL
  .| ..
IMNHPWM
Kinase ULK1.AA Ciliate-E2 9-272 21 6.1e-73 248.64 In-house 1-365 (365) Show / Hide 
Range on Protein: 9-272
Range on HMM: 1-365/365
Sequence Identity: 21% (82 aa)

YNKKDIIGHGAFAIVFRGRERKRPDQT-----------------VAIKCINKKNLSKSQ-TFPEKEIEILKELH----------------HGNVVSLLHF
|..  .|| |.|..|.... .| . |                  |.|| ...|...|.|  . ..|| |..|..                | |.. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

KE--TTSSLFMVMEFCNGGDLADYLHIKGTLS-----------EDTIRFFLGQIAC---------------AMKAIHEKG-IIHRDLKPQNLLLSHNSKH
 .  .......|||.|.|||| ||. .. . .           |  |...  ||.                |.. .|.|. |||||.||.|.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

KVPHPNEIHLKIADFGFARFLEGD--------------------------------MMAATLCGSPLYMAPEVITSQH---------YDAKADLWSIGTI
         .||.|||.....  |                                .|. |.||.| |||||.. ..          || |.|.||.| |
---------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVI

IFQCLTGSAPFKAANPPELKKLYMKARTLDPN--------------IPPGTSKALKDLLIR----LLKRNQKDRIE-FDKFFSHDFL
....|.|  ||       ...   .   ....              ..   |.  |||. .    .|..... ||  ... . | ..
LYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase ULK1.AA Ciliate-E2-Unclassified 9-272 24 6.1e-71 241.99 In-house 1-352 (352) Show / Hide 
Range on Protein: 9-272
Range on HMM: 1-352/352
Sequence Identity: 24% (87 aa)

YNKKDIIGHGAFAIVFRGRERKRPDQTVAIKCINKKNLSKSQTFPE--------KEIE----------------ILKELHHGNVVSLLHFKETTSSLFMV
|..  .||.|.|..|.. ...|   |  |.| ..|..  |..   .        ||..                ||. . | ..| ... ....  ...|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEFCNGGDLADYLHIKGT-----------------LSEDTIR-----FFLGQIACAMKAIHEKG-IIHRDLKPQNLLLSHNSKHKVPHPNEIHLKIADFG
||.|.|||| .|. ....                 ..|  ..     |.. || .. . .|.|. |||||.||.|.|.. | |         ..||.|||
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-------NYYIKIIDFG

FARFLE----------------GDMMAATLCGSPLYM----APEVITSQHYD----AKADLWSIGTIIFQCLTGSAPFKAANPPE---------------
......                 ..|. | ||.| ||    ||||. .|.||     |.| || | |....|.|  ||.. |  .               
ISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRK

-LKKLYMKARTLDPNIPP-----GTSKALKDLLI----RLLKRNQKDRIEFDKFFSHDFL
 |..  ..  .  |. |.     . |.  ||..     ..|| |.. || |.. . | ..
QLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase ULK1.AA MARK 9-272 33 3.4e-63 205.48 In-house 1-262 (262) Show / Hide 
Range on Protein: 9-272
Range on HMM: 1-262/262
Sequence Identity: 33% (91 aa)

YNKKDIIGHGAFAIVFRGRERKRPDQTVAIKCINKKNLSK-SQ-TFPEKEIEILKELHHGNVVSLLHFKE--TTSS-LFMVMEFCNGGDLADYLHIK--G
|  .  ||||..| |  .. ..   . |||| ..|..|..  .    . ||||.| |.| |...|.|  |  |..  ....|| . ||.| ||.  .  |
YKMLKTIGHGSYAKVKLACHKHTG-RKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

TLSEDTIRFFLGQIACAMKAIHEKGIIHRDLKPQNLLLSHNSKHKVPHPNEIHLKIADFGFARFLEGDMMAATLCGSPLYMAPEVITSQHYD-AKADLWS
 |.|.  | .  || .|..  |.|.|.|||.||.|.|. .| .|..        ||.||||..  . ...  | ||.| |||||.. .. ||  |.| ||
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNI--------KIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWS

IGTIIFQCLTGSAPFKAANPPELKKLYMKARTLDPNIPPGTSKALKDLLIRLLKRNQKDRIEFDKFFSHDFL
 | . .  ..|. ||....  ..|.|| | .. .. ||.  || ...|. |||. | ..|.  .   .| ..
LGVVLYFMVCGYFPFDGDT-QDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase ULK1.AA STE 9-272 21 8.5e-59 201.65 In-house 1-359 (359) Show / Hide 
Range on Protein: 9-272
Range on HMM: 1-359/359
Sequence Identity: 21% (79 aa)

YNKKDIIGHGAFAIVFRGRERK-----RPDQT---------VAIKCINKKNLS----------------KSQTFPEKEIEILKELH--HGNVVSLLHFKE
. . ..||.|||  |.... .|     . ...         .||| .|..| .                . .   .|||.|.|...  | |.|  .   .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TT-------SSLFMVMEFCNGGDLADYLHIK--------------GTLSEDTIRFFLGQIACA-MKAIHEKGIIHRDLKPQNLLLSHNSKHKVPHPNEIH
         ..|...||...|| | | .. |              ....|. |.... ||  . .. .|...|||||.||.| ||               
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------------

LKIADFGFARFLEGDM-----------------MAATLCGSPLYMAPEVITS------QHYDAKADLWSIGTIIFQCLTGSAPFKAANPPELKKLYMKAR
 |..|||..  |. .|                 .  |..|.| .||||||.       ..||.|.| ||.|  |   .||  |.   .|..   . ..  
VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNY

-------------TLDPNIPPGTS-------------------KALKDLLIRLLKRNQKDRIEFDKFFS--HDFL
                | .|. .|                   . .|| . . |... ..|   ..  .  | |.
HMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase ULK1.AA RSK 11-272 28 1e-58 201.35 In-house 1-278 (278) Show / Hide 
Range on Protein: 11-272
Range on HMM: 1-278/278
Sequence Identity: 28% (82 aa)

KKDI--IGHGAFAIVFRGRERKRPDQTVAIKCINKKNLSKSQT---FPEKEIEILKELH-HGNVVSLLHFKETTSSLFMVMEFCNGGDLADYLHIKGT--
 |.   .| |.. .. |  ...  .|  | | ..|. . ..|.      .|..||..   | ..|.| .  .| . |...||.|.||.| . |  ...  
LKVLGQGGYGKVFLC-RKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG

-LSEDTIRFFLGQIACAMKAIHEKGIIHRDLKPQNLLLSHNSKHKVPHPNEIHLKIADFGFARFLEGD--MMAATLCGSPLYMAPEVIT---SQH-YDAK
 .|||. .| . .|..|.. .|..||||||||| | |. . | .      | |.|. ||||.. .  |   .. | |..  |||||...    |  .|. 
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-N------EGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKA

ADLWSIGTIIFQCLTGSAPFKA---ANPPELKKLYMKARTLDPNIP--PGTSKALKDLLIRLLKRNQKDRIE-----FDKFFSHDFL
.|.|| | ...  |||  ||..   .|. |. |  .|.. .....|  .  |.. |||. ..|.|. ..|.       .   .| ..
CDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGK-FSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase ULK1.AA Pkinase_Tyr 9-200 28 2.6e-31 106.66 Pfam 1-199 (270) Show / Hide 
Range on Protein: 9-200
Range on HMM: 1-199/270
Sequence Identity: 28% (60 aa)

YNKKDIIGHGAFAIVFRGRER---KRPDQTVAIKCINKKNLSKS----QTFPEKEIEILKEL-HHGNVVSLLHFKE-TTSS--LFMVMEFCNGGDLADYL
  .   .|.|||  |..|. .   . ....||.|.. | . ...    . | . |..|.|.| || |.|.|.        .  ...|||.. .||| |||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HI----KGTLSEDTIRFFLGQIACAMKAIHEKGIIHRDLKPQNLLLSHNSKHKVPHPNEIHLKIADFGFARFL--EGDM-MAATLCGSPL-YMAPEVITS
.     |. |.  ..  .  |||..|   ..|..|||||   | |...          . . ||.||| || .  ..    ... .  |   ||||.|  
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----------NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINY

QHYDAKADLWS
  .  | | ||
GKFTTKSDVWS
Kinase ULK1.AA TyrKc 9-272 24 1.3e-23 85.71 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-272
Range on HMM: 1-280/280
Sequence Identity: 24% (73 aa)

YNKKDIIGHGAFAIVFRGRERKRPDQTVAIKCINKKNLSKSQTFPEKEIEILKEL--HHGNVVSLLHFKETT-------SSLFMVMEFCNGGDLADYLHI
  .....|.||| .|..|. .    ..||.|....      . |  .|..|...|  || |.| |.    .          |..|||.. .||| |||. 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA---REDF-MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KGT-LSEDTIRFFLGQIACAMKAIHEKGIIHRDLKPQNLLLSHNSKHKVPHPNEIHLKIADFGFARFLEGD--------MMAAT---LCG--SPL-YMAP
..  |. ..   |  |||| |  .|.|..|||||   | |...|           . ||.||| .|... |        .  ..    .    |.  |||
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

EVITSQHYDAKADLWSIGTIIFQCLT-GSAPFKA-----ANPPELKKLYMKARTLDPNIPPG--------TSKALKDLLIRLLKRNQKDRIEFDKFFSHD
|.|    .  | | || |  ..  .| |  |         .. |. .. .. . ...  ||          .... ..  .  ... .||  |     |.
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQ--PPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HE

FL
..
CF
DUF3543 ULK1.AA DUF3543 741-952 19 2.4e-28 101.72 Pfam 1-275 (275) Show / Hide 
Range on Protein: 741-952
Range on HMM: 1-275/275
Sequence Identity: 19% (54 aa)

ETLLAAEHTETVDRLNVILGIVEAIVEVAKSRSVPLAESI-----YNQGSSIF---------SNSQVCFVSENYRLAEQLVLYTRSLELLNAALTMAKEE
.|..  |||.||..|. ..    .. ..| ..  .|. .      |  | .             ...  ... .. .|.|||| ..|.|| .... |.. 
QTSMDDEHTRTVQKLEECATRSDCVYGFAEVKYKQLIPLMPSVSTYGLGDANVQGRDDSMHQDDGLTPDAIVTWKSEEALVLYVKALSLLAKSMDIASAW

FSA--------------ARLKP-SNAVRTVLQELNRVYHLCLIKSRQLCEGS-----PLQSLDIDLNS------------------AMITADKLMYSYAI
 .                 |.| ||..  |.| ..  .. || |.  . .        |.  . .. .                    .||.||||. |.
WYRKNRGEDFNMTRDSSNQLCPTSNRINQVVQWIRERFNECLEKCEFVRLKLQEAQKRLPEDHPSHPKNHSNESSSSGSSNDVVVSSGVTAEKLMYDRAL

EQCQSAGMDEMFG-NTQECLQRYRTAQMLLHGLCLQA----------GTDHDRNLLLKFKNALDQRLLFLERQQT
| ...| ..|.|| ... | ..|.||...|..|  .             | |. .. |.. .   ||  | ... 
EMSRTAAINELFGEDLPGCEIAYHTAIWMLEALLENDEDEDKDENDGLDDEDKQMVEKYIVSIRKRLSVLRKKMY