Gene Spk373 (Sea Urchin)

Spk373

Species: Sea Urchin
Alias: SPU_011645, Spk373
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
Spk373.AA Protein None 539 None Fasta, JSON
Spk373.kin_dom Protein Kinase Domain None 93 None Fasta, JSON

Protein domain

Protein domains of Spk373.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Spk373.AA CAMKL 148-188 41 1.6e-15 45.84 In-house 175-222 (297) Show / Hide 
Range on Protein: 148-188
Range on HMM: 175-222/297
Sequence Identity: 41% (20 aa)

FATNCAD-----GEKLTEACGSMGYVAPEILEG--DPYEGKPVDLWSM
|.. . .     |.||.. |||  | ||||..|  .||.|..|| ||.
FSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSC
Kinase Spk373.AA CAMK 146-188 23 1.7e-14 42.46 In-house 240-320 (425) Show / Hide 
Range on Protein: 146-188
Range on HMM: 240-320/425
Sequence Identity: 23% (19 aa)

FQFATNCAD------------------------GEKLTEACGSMGYVA-PEILEG-------------DPYEGKPVDLWSM
| ||. . .                        |.|... ||. .|.| ||.|.|              || |...| ||.
FGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSC
Kinase Spk373.AA CAMK1 152-187 45 2.4e-14 38.06 In-house 163-201 (276) Show / Hide 
Range on Protein: 152-187
Range on HMM: 163-201/276
Sequence Identity: 45% (18 aa)

CADGE-KLTEACGSMGYVAPEILEG---DPYEGKPVDLWS
. ..| ... |||. ||||||.||.   .|| .|..|.||
FDHDENLMKTACGTPGYVAPEVLECKKDKPY-DKACDMWS
Kinase Spk373.AA CAMK 57-145 18 3.9e-14 41.24 In-house 1-159 (425) Show / Hide 
Range on Protein: 57-145
Range on HMM: 1-159/425
Sequence Identity: 18% (29 aa)

VMNRGQYCKVIHVYSKKRNCD------------FALKIFCKLSAPD-------------------------IVKKKFFPQEILIMKKLS-------HDHV
.  ||...||  .. |. ...            .| ||  |  ..|                          ...|....|| |||||.       | ..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LGLVEVLL------------TNRN--------GYLLM---DFMPNG----SLRSYINKQE
. | ||              | ..         |. |   .....|     | .|| ...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHG
Kinase Spk373.AA MARK 148-188 43 3.9e-14 42.78 In-house 152-192 (262) Show / Hide 
Range on Protein: 148-188
Range on HMM: 152-192/262
Sequence Identity: 43% (18 aa)

FATNCADGEKLTEACGSMGYVAPEILEGDPYEGKPVDLWSM
|.. .  |.||.. ||.  | ||||... ||.|..|| ||.
FSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSL
Kinase Spk373.AA S_TKc 52-217 16 1.9e-12 5.47 SMART 1-231 (231) Show / Hide 
Range on Protein: 52-217
Range on HMM: 1-231/231
Sequence Identity: 16% (42 aa)

LLMGNVMNRGQYCKVIHVYSKKRNCDFALKIFCKLSAPDIVKKKFFPQEILIMKKLSHDHVLGLVEVLLTNRNGYLLMDFMPN--GSLRSYINKQEFQ--
  ....  .| . ||  .. || .  .|.||            . . .|| |.||  |...  | .|  .  . |. |.....  |.|..|| |.  .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-------------------------------------------------FATNCADGEKLTEACGSMGYVAPEILEGDPYEGKPVDLWSM----------
                                                 .|.        |  ||.  |.|||.|   .| ....| ||           
RFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

-----------------DCRAFVHALLVPQPQKRAKFSDLAK-------MEWL
                 ... |.  .|.  |.||    .. .       ..|.
YPPFPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Spk373.AA CAMKL 52-144 24 1.3e-11 33.15 In-house 1-117 (297) Show / Hide 
Range on Protein: 52-144
Range on HMM: 1-117/297
Sequence Identity: 24% (29 aa)

LLMGNVMNRGQYCKVIHVYSKKR-NCDFALKIFC--KLSAPDIVKKKFFP----------QEILIMKKLS---HDHVLGLVEVLLTNRN------GYLLM
  .| .  .| . ||     ..  ..  | ||    |..  ...||.. .          .|| |||.|.   | ..  | ||. | ..       || |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

DFMPNGS--LRSYINKQ
   ..|.  |  || |.
EYCSGGEMDLFDYIVKH
Kinase Spk373.AA Pkinase 60-141 24 1.3e-11 42.1 Pfam 9-95 (293) Show / Hide 
Range on Protein: 60-141
Range on HMM: 9-95/293
Sequence Identity: 24% (21 aa)

RGQYCKVIHVYSKKRNCDFALKIFCKLSAPDIVKKKFFP-QEILIMKKLSHDHVLGLVEVLLTNRNGYLLMDFMPNG----SLRSYI
.| . .| . . |. .. .|.||..| .. . ...  .  .|| |||.|.|.... | ..  .... |. |.....|    .| .||
SGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI
Kinase Spk373.AA SNRK 146-188 51 5e-11 32.06 In-house 144-186 (254) Show / Hide 
Range on Protein: 146-188
Range on HMM: 144-186/254
Sequence Identity: 51% (22 aa)

FQFATNCADGEKLTEACGSMGYVAPEILEGDPYEGKPVDLWSM
| |.     ||||.  |||. | ||||| || |.   ||.||.
FGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSL
Kinase Spk373.AA AMPK 152-187 52 6.9e-11 28.62 In-house 150-185 (254) Show / Hide 
Range on Protein: 152-187
Range on HMM: 150-185/254
Sequence Identity: 52% (19 aa)

CADGEKLTEACGSMGYVAPEILEGDPYEGKPVDLWS
. |||.|  ||||  | |||. .| .|.|  ||.||
MKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWS
Kinase Spk373.AA Ciliate-E2a 61-148 30 3.9e-10 26.07 In-house 10-98 (275) Show / Hide 
Range on Protein: 61-148
Range on HMM: 10-98/275
Sequence Identity: 30% (27 aa)

GQYCKVIHVYSKKRNCDFALKIFCKLSAPDIVKKKFFPQEILIMKKLSHDHVLGLVEVLLTNRNGYLLMDFMPNGSLRSYINKQE-FQF
|.. .| ..  |. . .|| |.| |  . .  .|..| .|| ||..|.|.... | ||  ...| || |..   |.| ..|...  |..
GNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFE
Kinase Spk373.AA TSSK 52-115 30 8.7e-10 28.28 In-house 1-81 (289) Show / Hide 
Range on Protein: 52-115
Range on HMM: 1-81/289
Sequence Identity: 30% (25 aa)

LLMGNVMNRGQYCKVIHVYSKKRNCD----------------FALKIFCKLSAPDIVKKKFFPQEILIMKK-LSHDHVLGL
. .|..  .| | ||.  ||||..|                  | ||  .  ||. ...||.| || ||.| | |...  .
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQF
Kinase Spk373.AA MARK 53-141 32 9.9e-10 28.17 In-house 2-93 (262) Show / Hide 
Range on Protein: 53-141
Range on HMM: 2-93/262
Sequence Identity: 32% (30 aa)

LMGNVMNRGQYCKVIHVYSKKRNCDFALKIFCKLSAPDIVKKKFFPQEILIMKKLSHDHVLGLVEVLL--TNRN-GYLLMDFMPNGSLRSYI
 |. .   | |.||  . .|. .  .|.||  | .  |  ..| .  || |||||.| ..  | .|    |...  || |.  ..|.|..||
KMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYI
Kinase Spk373.AA TSSK 162-188 62 1.1e-09 27.95 In-house 189-215 (289) Show / Hide 
Range on Protein: 162-188
Range on HMM: 189-215/289
Sequence Identity: 62% (17 aa)

CGSMGYVAPEILEGDPYEGKPVDLWSM
|||  |.||||| | || .| .| |||
CGSYAYAAPEILRGIPYDPKWYDVWSM
Kinase Spk373.AA GIN4 145-198 42 1.3e-08 23.15 In-house 178-229 (293) Show / Hide 
Range on Protein: 145-198
Range on HMM: 178-229/293
Sequence Identity: 42% (23 aa)

EFQFATNCADGEKLTEACGSMGYVAPEILEGDPYEGKPVDLWSMDCRAFVHALL
.|  |    |.. |  .|||  | ||||  | ||.| . | ||  |   . |||
DFGMAALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWS--CGVILFALL
Kinase Spk373.AA Ciliate-E2 52-144 21 2.7e-07 21.1 In-house 1-128 (365) Show / Hide 
Range on Protein: 52-144
Range on HMM: 1-128/365
Sequence Identity: 21% (27 aa)

LLMGNVMNRGQYCKVIHVYSKKRNCDFALKIFCKL--------------SAPDIVKK---KFFPQEILIMK----------------KLSHDHVLGLVEV
    ..  .|.. .|  .  .| ...||.||. ..               |  |.||   ... ||| ||.                .|.|.... ..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LL--TNRNGYLLMDFMPNGSLRSYINKQ
    .. | || |..   |.|..||...
FQEKDDNNIYLVMEYCQGGDLFDYIKNN
Kinase Spk373.AA Ciliate-E2 146-188 19 1e-06 18.88 In-house 200-282 (365) Show / Hide 
Range on Protein: 146-188
Range on HMM: 200-282/365
Sequence Identity: 19% (16 aa)

FQFATNCAD-----------GEKLTEA----------------------CGSMGYVAPEILEGDPYEG--------KPVDLWSM
| ..... |           ....                         ||. ||.|||||.| .|..        . .|.||.
FGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSL
Kinase Spk373.AA Pkinase 155-188 41 1e-06 24.33 Pfam 166-198 (293) Show / Hide 
Range on Protein: 155-188
Range on HMM: 166-198/293
Sequence Identity: 41% (14 aa)

GEKLTEACGSMGYVAPEILEGDPYEGKPVDLWSM
.. .|  ||. .|.|||.. |..| |..|| ||.
NS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC
Kinase Spk373.AA TyrKc 52-217 13 2e-06 -118.22 SMART 1-280 (280) Show / Hide 
Range on Protein: 52-217
Range on HMM: 1-280/280
Sequence Identity: 13% (38 aa)

LLMGNVMNRGQYCKVIH-VYSKKRNCDFALKIFCKLSAPDIVKKKFFPQEILIMKKL--SHDHVLGLVEVLLTN-------RNGYLLMDFMPNGSLRSYI
. .| .  .|....| . ...        ..   |   .|   .. | .|. ||.||  .|.... |. | ..           ...| .||.|.|..|.
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

NKQE--------FQFATNCADG-----------------------EK--------LTEACGSM-------GYV-----------------APEIL-----
 | .         .|..  |.|                       ..        |. . ..         |                  ||| .     
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

-------------------EGDPYEG------KPVDLWSM-----------D--------CRAFVHALLV----PQPQKRAKFSDLAKMEWL
                    . ||.|      .. ..              .        | . .. .       .| .|  ||..   | .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase Spk373.AA GIN4 100-141 40 3e-06 15.47 In-house 84-125 (293) Show / Hide 
Range on Protein: 100-141
Range on HMM: 84-125/293
Sequence Identity: 40% (17 aa)

EILIMKKLSHDHVLGLVEVLLTNRNGYLLMDFMPNGSLRSYI
||.||| .||  |. | .|  || . ||....   | |  |.
EIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYL
Kinase Spk373.AA AMPK 100-145 34 3e-06 14.47 In-house 49-95 (254) Show / Hide 
Range on Protein: 100-145
Range on HMM: 49-95/254
Sequence Identity: 34% (16 aa)

EILIMKKLSHDHVLGLVEVL-LTNRNGYLLMDFMPNGSLRSYINKQE
|| |.|.. | |.  | ||.  |..  .. | . ..| | .|| | .
EIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHG
Kinase Spk373.AA SNRK 189-217 31 1.6e-05 13.75 In-house 226-254 (254) Show / Hide 
Range on Protein: 189-217
Range on HMM: 226-254/254
Sequence Identity: 31% (9 aa)

DCRAFVHALLVPQPQKRAKFSDLAKMEWL
.||  .. .|| .|.|||   ...   |.
ECRDLIQSMLVRDPKKRASLEEIVSHSWV
Kinase Spk373.AA Ciliate-E2a 149-173 40 0.000253 8.66 In-house 156-182 (275) Show / Hide 
Range on Protein: 149-173
Range on HMM: 156-182/275
Sequence Identity: 40% (11 aa)

ATNC--ADGEKLTEACGSMGYVAPEIL
||..   .....   ||. ||||||.|
ATFIDKDEKKYMFQKCGTPGYVAPEVL
Kinase Spk373.AA AMPK 189-217 20 0.000253 8.81 In-house 226-254 (254) Show / Hide 
Range on Protein: 189-217
Range on HMM: 226-254/254
Sequence Identity: 20% (6 aa)

DCRAFVHALLVPQPQKRAKFSDLAKMEWL
...  .. .| . |.||....|. . .|.
EAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase Spk373.AA Pkinase_Tyr 99-140 32 0.000412 14.55 Pfam 52-97 (270) Show / Hide 
Range on Protein: 99-140
Range on HMM: 52-97/270
Sequence Identity: 32% (15 aa)

QEILIMKKL-SHDHVLGLVEVLL-TNRN--GYLLMDFMPNGSLRSY
.|. |||.| .|.... |. | .   .    |. | .||.|.|..|
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY
Kinase Spk373.AA MARK 189-217 27 0.00042 9.5 In-house 234-262 (262) Show / Hide 
Range on Protein: 189-217
Range on HMM: 234-262/262
Sequence Identity: 27% (8 aa)

DCRAFVHALLVPQPQKRAKFSDLAKMEWL
.|| ... ||.. | .|.. ... | .|.
ECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase Spk373.AA CAMKL 189-217 27 0.000478 8.64 In-house 269-297 (297) Show / Hide 
Range on Protein: 189-217
Range on HMM: 269-297/297
Sequence Identity: 27% (8 aa)

DCRAFVHALLVPQPQKRAKFSDLAKMEWL
||| . . .|.. | ||..  .. . .|.
DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase Spk373.AA CAMK 189-217 20 0.000799 7.41 In-house 397-425 (425) Show / Hide 
Range on Protein: 189-217
Range on HMM: 397-425/425
Sequence Identity: 20% (6 aa)

DCRAFVHALLVPQPQKRAKFSDLAKMEWL
.|. ..  .|.. |.||.. ..  . .|.
ECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Spk373.AA TSSK 189-217 20 0.001409 7.59 In-house 261-289 (289) Show / Hide 
Range on Protein: 189-217
Range on HMM: 261-289/289
Sequence Identity: 20% (6 aa)

DCRAFVHALLVPQPQKRAKFSDLAKMEWL
.|.. .  .| |.| .|..  . .. .|.
ECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase Spk373.AA Ciliate-E2 197-217 22 0.004479 6.38 In-house 344-365 (365) Show / Hide 
Range on Protein: 197-217
Range on HMM: 344-365/365
Sequence Identity: 22% (5 aa)

LLVPQPQKRAK-FSDLAKMEWL
.|. .|.||   .... . .|.
MLQKDPEKRITGWEQILNHPWF
Kinase Spk373.AA SNRK 79-145 29 0.021169 3.36 In-house 28-93 (254) Show / Hide 
Range on Protein: 79-145
Range on HMM: 28-93/254
Sequence Identity: 29% (20 aa)

ALKIFCKLSAPDIVKKKFFPQEILIMKKLSHDHVLGLVEVLLTNRNGYLLMDFMPNGSLRSYINKQE
| |.  |.   .. | . | ||.  ||   |  .  | ||. |    ||...    . .  || | |
AVKVIDKTKMDEVSKAHLF-QEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHE