Gene NEK4 (Sea Urchin)

NEK4

Species: Sea Urchin
Alias: NEK4, Spk179, SPU_023369
External Links: Sea Urchin Project Link ,
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK4

Sequence

Name Sequence Type Origin Length Description Download
NEK4.AA Protein None 544 None Fasta, JSON
NEK4.kin_dom Protein Kinase Domain None 127 None Fasta, JSON

Protein domain

Protein domains of NEK4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NEK4.AA NEK4 6-132 76 2.5e-100 339.59 In-house 1-128 (257) Show / Hide 
Range on Protein: 6-132
Range on HMM: 1-128/257
Sequence Identity: 76% (98 aa)

YEHLKVVGKGSYGEVWLVRNKKDKKQFVIKKMELLRASKREKKAAEQEAKLLSKLRHPNIVSYKDSFESEEG-FLYIVMGFCDGGDLYNRLKQQKNAALE
|.|.|||||||||||||||...||||.|.|||.|..||.||.||||.||.|||.|.|||||.||.|.|.|.| |||||||||.|||||..||||||..||
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFLE

ERQVVEWFVQIAMALQYMHERNILHRDL
|.||||||||||||||||||..||||||
EYQVVEWFVQIAMALQYMHEKHILHRDL
Kinase NEK4.AA NEK 6-132 43 3.2e-68 232.97 In-house 1-145 (286) Show / Hide 
Range on Protein: 6-132
Range on HMM: 1-145/286
Sequence Identity: 43% (63 aa)

YEHLKVVGKGSYGEVWLVRNKKDKKQ-----FVIKKMELLRASKREKKAAE-QEAKLLSKLRHPNIVSYKDSFESEE-GFLYIVMGFCD-GGDLYNR---
||..|..|.||.|.|..|| |.|.|.     .|.||. . . | .||..|  .|...|..|.|||||.|.|||. |. ..|.||| .|. |||||..   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

LKQQK--NAALEERQVVEWFVQIAMALQYMHER-----NILHRDL
.|.||  .  .||.|...||.|...||.|||.|     .|||||.
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDI
Kinase NEK4.AA NEK1 6-132 44 3.8e-57 196.16 In-house 1-130 (276) Show / Hide 
Range on Protein: 6-132
Range on HMM: 1-130/276
Sequence Identity: 44% (58 aa)

YEHLKVVGKGSYGEVWLVRNKKDKKQFVIKKMELLRASKREKKAAEQEAKLLSKLRHPNIVSYKDSFESEEGF--LYIVMGFCDGGDLYNRLKQQ--KNA
|. .|..|.||.| .|||. | | ...|||   . . .. |. ..  |...|.|..|||||.||.||| |.|   ||||| .||||||. . ..|  |. 
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFE-ENGCGILYIVMEYCDGGDLMQKINRQKRKGK

ALEERQVVEWFVQIAMALQYMHERNILHRDL
   | |   ||.|| .||...| |.|||||.
LFSEDQIMHWFCQICLALNHIHDRKILHRDI
Kinase NEK4.AA NEK8 6-132 37 3.9e-53 149.97 In-house 1-145 (278) Show / Hide 
Range on Protein: 6-132
Range on HMM: 1-145/278
Sequence Identity: 37% (55 aa)

YEHLKVVGKGSYGEVWLVRNKKDK--KQFVIKKMELLRASKREKKAAEQEAKLLSKLRHPNIVSYKDSFESEEGFLYIVMGFCDGGDLYNRLKQQKN-AA
||   |||.|. |..|| | | |   .. ..|   . | |..|  .|  |  .||.| ||||.|| |.|. |.. | |.|  .||| ||  .  |.|   
YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFM-EDNTLMIEMEYADGGTLYQMIQHQQNKLF

LEER----------------QVVEWFVQIAMALQYMHERNILHRDL
.|||                ...  |.|.  |. .||. |||||||
EEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDL
Kinase NEK4.AA S_TKc 6-215 25 1.3e-48 168.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 6-215
Range on HMM: 1-231/231
Sequence Identity: 25% (67 aa)

YEHLKVVGKGSYGEVWLVRNKKDKKQFVIKKMELLRASKREKKAAEQEAKLLSKLRHPNIVSYKDSFESEEGFLYIVMGFCDG--GDLYNRLKQQKNAA-
|| |...|||..|.|...|.||..... ||..          . ...| ..|.| .||||| ..|.|..  ..||.|| .|||  |||. ..|...    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LEERQVVEWFVQIAMALQYMHERNILHRDL-----------------------------------YIVGDTN-QSDVWALGCCVYEMTTLKHAFNAK
   . | ..  .. ||. ||.|.|...|.||||                                    . | .   .|.|..||..||| . .  |   
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFP--

DMNSLVYKILRGKMPAMPQQYSIELVELIKATLNQSPEKRPSVSRVLR-------NPYI
    ...|...          | |. ..|.  |.  |||||..  .|.        |..
-QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NEK4.AA NEK4 141-215 57 1.7e-43 150.83 In-house 183-257 (257) Show / Hide 
Range on Protein: 141-215
Range on HMM: 183-257/257
Sequence Identity: 57% (43 aa)

SDVWALGCCVYEMTTLKHAFNAKDMNSLVYKILRGKMPAMPQQYSIELVELIKATLNQSPEKRPSVSRVLRNPYI
||.|.|||||||| ||||||.|||||||.|.|. |..| ||..|| .| .|..  |.. |.||||.  ... |||
SDIWSLGCCVYEMITLKHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase NEK4.AA CAMK 11-132 19 2.1e-39 124.13 In-house 1-205 (425) Show / Hide 
Range on Protein: 11-132
Range on HMM: 1-205/425
Sequence Identity: 19% (40 aa)

VVGKGSYGEVWLVRNKKDK------------KQFVIKKMELLRAS--------------------------KREKKAAEQEAKLLSK-------LRHPNI
. |.||.|.| |...|...            ... || ..  ...                           . .|  ..| ....|       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSYKDSFE------------SEEG-------FLYIVM---GFCDGG----DLYNRLKQQKN-------------AALEERQVVEWFVQIAMALQYMHERN
..  . .|            . .        ..|.||    .|.||    ||.........               ..||..  .| ||. |..|.|..|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ILHRDL
| ||||
IVHRDL
Kinase NEK4.AA Pkinase 6-132 28 2.4e-39 140.2 Pfam 1-134 (293) Show / Hide 
Range on Protein: 6-132
Range on HMM: 1-134/293
Sequence Identity: 28% (38 aa)

YEHLKVVGKGSYGEVWLVRNKKDKKQFVIKKMELLRASKREKKAAEQ--EAKLLSKLRHPNIVSYKDSFESEEGFLYIVMGFCDGG----DLYNRLKQQK
|. ....|.||.|.|.. ..|.. |....|.... .... .....    |.... .|.||||| ..|.||. .. .|.|| .|.||    ||. ... ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR

NAAL--EERQVVEWFVQIAMALQYMHERNILHRDL
. ..  .|...  .. ||. .|.|.|...|.||||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDL
Kinase NEK4.AA Ciliate-E2 6-132 22 1e-35 120.07 In-house 1-187 (365) Show / Hide 
Range on Protein: 6-132
Range on HMM: 1-187/365
Sequence Identity: 22% (42 aa)

YEHLKVVGKGSYGEVWLVRNKKDKKQF------------------VIKKMELLRASKREKKAAEQEAKLLSKLR----------------HPNIVSYKDS
|. .|. |.|..| |......|..|||                   ||. .. . .|..... .|| ... ...                ||||. ....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FES-EEGFLYIVMGFCDGGDLYNRLKQQKNA---------ALEERQVVEWFVQIA---------------MALQYMHERN-ILHRDL
|..  .  .|.|| .|.||||. ..|..|            . |... . . ||.                ||.|.|..| |.|||.
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDI
Kinase NEK4.AA NEK 138-215 44 2e-35 122.38 In-house 202-286 (286) Show / Hide 
Range on Protein: 138-215
Range on HMM: 202-286/286
Sequence Identity: 44% (38 aa)

TNQSDVWALGCCVYEMTTL--KHAFNAK--DMNSLVYKILRG-KMPAMPQQ--YSIELVELIKATLNQSPEKRPSVSRVLRNPYI
.| ||.|.|||..||| ||  ||.|.|.  .|.||..|| .| . |  |..  || .| .||   |. .||.|||.. .| .|.|
NNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase NEK4.AA Ciliate-E2-Unclassified 6-132 25 6e-32 108.11 In-house 1-170 (352) Show / Hide 
Range on Protein: 6-132
Range on HMM: 1-170/352
Sequence Identity: 25% (44 aa)

YEHLKVVGKGSYGEVWLVRNKKDK--------KQFVIKKMELLRASKREKKAAEQEAK----------------LLSKLRHPNIVSYKDSFESEEGFLYI
|. .|. |.|..|.|.....||.|        |.. |.|. . . .. |..  ..| .                .|. . ||.|| . . |....  .||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQ-NIYI

VMGFCDGGDLYNRLKQQKN---------------AALEERQVV-----EWFVQIAMALQYMHERN-ILHRDL
|| .|.|||| . .|..|.                 ..|.|..      .| ||  .|.|.|. | |.|||.
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDI
Kinase NEK4.AA NEK-Unclassified 6-132 40 2.2e-30 97.54 In-house 1-123 (258) Show / Hide 
Range on Protein: 6-132
Range on HMM: 1-123/258
Sequence Identity: 40% (52 aa)

YEHLKVVGKGSYGEVWLVRNKKDKKQFVIKKMELLRASKREKKAAEQE-AKLLSKLRHPNIVSYKDSFESEEGFLYIVMGFCDGGDLYNRLKQQ--KNAA
|. .  .|.|  | |.||| .  |.  | .       ||| ||   |    .||.|||| || | |||  |   |.    .||||.|  |.. .  || .
YDKITTLGQGGGGAVYLVRHQISKRHLVQQ------ISKRKKKKKRQNKIIILSQLRHPHIVTYHDSF-FENAKLFYTQDYCDGGNLDRRIQKHRKKNEP

LEERQVVEWFVQIAMALQYMHERNILHRDL
..|  .  |..|. ||.|| | | |.||||
FDEGRIMQWCIQMIMAVQYIHQRKIIHRDL
Kinase NEK4.AA NEK1 138-215 44 7e-30 100.92 In-house 199-276 (276) Show / Hide 
Range on Protein: 138-215
Range on HMM: 199-276/276
Sequence Identity: 44% (35 aa)

TNQSDVWALGCCVYEMTTLKHAFNAKDMNSLVYKILRGKMPAMPQQYSIELVELIKATLNQSPEKRPSVSRVLRNPYI
.| ||.|.|||  || .||||.|.|. .  || ||..|  |  |. || || .|..  .. .|. ||||  .|  | |
NNKSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase NEK4.AA NEK8 141-215 42 8.9e-30 82.1 In-house 203-278 (278) Show / Hide 
Range on Protein: 141-215
Range on HMM: 203-278/278
Sequence Identity: 42% (32 aa)

SDVWALGCCVYEMTTLKHAFNAKDMNSLVYKILRG-KMPAMPQQYSIELVELIKATLNQSPEKRPSVSRVLRNPYI
||.|||||  ||| .|| || |     || || .. ..   . .|| |.  |. . | | ||.|||.| .. .| .
SDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase NEK4.AA NEK11 6-132 40 3e-25 88.87 In-house 1-131 (259) Show / Hide 
Range on Protein: 6-132
Range on HMM: 1-131/259
Sequence Identity: 40% (53 aa)

YEHLKVVGKGSYGEVWLVRNKKDKKQ---FVIKKMELLRASKREKKAAEQEAKLLSKLRHPNIVSYKDSFESEEGFLYIVMGFCDGGDLYNRLKQQKNAA
|   . .| ||.| |.||  || |.     |.| .        |   |  ||.|||.| || || .  ||   . |  |.  .|.| || .|..  |.| 
YVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANVEAQLLSRLHHPAIVRFHASFMEQDNFC-IITEYCEGRDLDYRIQEYKQAG

--LEERQVVEWFVQIAMALQYMHERNILHRDL
    | |..|||.|. .   ||||| ||||||
KIFPENQIIEWFIQLLLGVDYMHERRILHRDL
Kinase NEK4.AA NEK2 141-215 38 2.2e-21 68.67 In-house 245-319 (319) Show / Hide 
Range on Protein: 141-215
Range on HMM: 245-319/319
Sequence Identity: 38% (29 aa)

SDVWALGCCVYEMTTLKHAFNAKDMNSLVYKILRGKMPAMPQQYSIELVELIKATLNQSPEKRPSVSRVLRNPYI
||.|..|| .||| .|.  | |.    |  ||  |.    | ||| .| |.|   .|  ...|||.   |..| |
SDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMINVDHYHRPSIEEILQHPQI
Kinase NEK4.AA Pkinase_Tyr 6-132 26 1.7e-20 70.02 Pfam 1-137 (270) Show / Hide 
Range on Protein: 6-132
Range on HMM: 1-137/270
Sequence Identity: 26% (37 aa)

YEHLKVVGKGSYGEVWLVRNK----KDKKQFVIKKMELLRASKRE--KKAAEQEAKLLSKL-RHPNIVSYKDSFESEEGF--LYIVMGFCDGGDLYNRLK
 . .|. |.|..|||.. . |    ..| .  .|..    |....  ...  .|||....| .|||||..     ....   .|||| .. .|||.. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

QQ--KNAALEERQVVEWFVQIAMALQYMHERNILHRDL
..   . .|   . ... .|||....| ...|. ||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase NEK4.AA NEK-Unclassified 139-215 32 1.9e-20 64.11 In-house 176-258 (258) Show / Hide 
Range on Protein: 139-215
Range on HMM: 176-258/258
Sequence Identity: 32% (27 aa)

NQSDVWALGCCVYEMTTLKHAFNAKDMNSLVYKILRGKM-------PAMPQQYSIELVELIKATLNQSPEKRPSVSRVLRNPYI
|.||||.||| .||| |   .| .. | .. .|| ..         |   . ||  | ..|.  | . ...|||   ..  .||
NRSDVWSLGCIIYEMCTCEPFFDTHNMGEVYMKIKQDDNRLEEALEP-VSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI
Kinase NEK4.AA NEK2 6-132 31 2.4e-20 65.12 In-house 1-151 (319) Show / Hide 
Range on Protein: 6-132
Range on HMM: 1-151/319
Sequence Identity: 31% (48 aa)

YEHLKVVGKGSYGEVWLVRNKKDKKQFVIKKMELLRASKREKKAAEQEAKLLSKLRHPNIVSYKDS-FESEEGFLYIVMGFCDGGDLYNRLKQQKNAA--
|| |.. |.||.| .  || | |.| .| | ..       |. .   |  .|..|.||||| | |  .  ..  ||||| .| ||||    |  ..    
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

LEERQVVEWFVQIAMALQYMHE------------------RN---ILHRDL
.||  .   . |.  |||  |                    .   |||||.
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDI
Kinase NEK4.AA NEK11 140-215 38 5.9e-20 69.36 In-house 184-259 (259) Show / Hide 
Range on Protein: 140-215
Range on HMM: 184-259/259
Sequence Identity: 38% (29 aa)

QSDVWALGCCVYEMTTLKHAFNAKDMNSLVYKILRGKMPAMPQQYSIELVELIKATLNQSPEKRPSVSRVLRNPYI
.||.|.| | .|||  . |||   .  |.| .|  |. |..|. |  ||  ..   ||..|  |||   .|. ||.
KSDIWSLACILYEMCCMDHAFAGSNFLSIVLNIVEGDTPSLPDRYPRELNTIMERMLNKNPSLRPSAIDILKIPYM
Kinase NEK4.AA TyrKc 6-219 20 5.3e-14 3.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 6-219
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

YEHLKVVGKGSYGEVWLVRNKKDKKQFVIKKMELLRASKREKKAAEQEAKLLSKL--RHPNIVSYKDSFESEE------GFLYIVMGFCDGGDLYNRLKQ
 . .|. | | .|||.. . |    . |  ||    |    ...  .||....||  .|||||       ...      . |.||| ....||| ..|. 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

QKNAALEERQVVEWFVQIAMALQYMHERNILHRDL-----------------------------------YIV------GD------------------T
 ..  |  .. ... .|||   .| |..|. ||||                                   |..      |.                  |
HRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

NQSDVWALGCCVYEMTTLKHAFNA------KDMNSLVYKILRGKMPAMPQQ--------YSIELVELIKATLNQSPEKRPSVSRVLRNPYIKKHI
 .||||. | | .|. |.            ..   .. .. .|...  |.          . |. ...|   .  ||.||. | .      .. .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF
Kinase NEK4.AA Pkinase 136-215 18 3.5e-13 47.68 Pfam 188-293 (293) Show / Hide 
Range on Protein: 136-215
Range on HMM: 188-293/293
Sequence Identity: 18% (20 aa)

GDTNQSDVWALGCCVYEMTTLKHAFNAK------DMNSLVYKILRGKMPAMPQQYS--------------------IELVELIKATLNQSPEKRPSVSRV
...  .|.|..|| .||| . .  |  .      |.. ....|.... .   .. .                     |. ..||  |.. |.|||.   .
YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

LRNPYI
|  |..
LQHPWF
Kinase NEK4.AA Ciliate-E2 140-215 22 9.9e-11 33.05 In-house 276-365 (365) Show / Hide 
Range on Protein: 140-215
Range on HMM: 276-365/365
Sequence Identity: 22% (22 aa)

QSDVWALGCCVYEMTTLKHAFNAKDMNSLVYKILRGKMPAMP------------------QQYSIELVELIKA----TLNQSPEKRPS-VSRVLRNPYI
..|.|.||.. ||| . |. |         ...   .    |                  .. | |   |||      |.  ||||..  . .| .|..
KCDIWSLGVILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase NEK4.AA CAMK 136-215 19 4.6e-09 24.61 In-house 310-425 (425) Show / Hide 
Range on Protein: 136-215
Range on HMM: 310-425/425
Sequence Identity: 19% (23 aa)

GDTNQSDVWALGCCVYEMTTLKHAFNAKDMNSLVY-------------KILRGKMPAMPQQYSI-----------------------ELVELIKATLNQS
... ..|.|..|.  | | . .  |.... |. .              ||..||    | . |.                       |   ||.  |.  
YYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVD

PEKRPSVSRVLRNPYI
||||.... .|. | .
PEKRMTIEQCLNHPWM
Kinase NEK4.AA Ciliate-E2-Unclassified 140-215 19 1.1e-07 22.74 In-house 250-352 (352) Show / Hide 
Range on Protein: 140-215
Range on HMM: 250-352/352
Sequence Identity: 19% (20 aa)

QSDVWALGCCVYEMTTLKHAFNAKDMNS---------------LVYKILRGKMPA--------MPQQYSIELVELIK----ATLNQSPEKRPSVSRVLRN
..|.|.||.. ||| . .. |.... ..                .|..   | .          |.. | |  ..|.      |.  |.||.. . .|  
KCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNH

PYI
|..
PWF
Kinase NEK4.AA Pkinase_Tyr 140-156 41 0.179515 5.61 Pfam 194-210 (270) Show / Hide 
Range on Protein: 140-156
Range on HMM: 194-210/270
Sequence Identity: 41% (7 aa)

QSDVWALGCCVYEMTTL
.||||. | . .|. |.
KSDVWSFGVLMWEIFTY