Gene NLK (Sea Urchin)

NLK

Species: Sea Urchin
Alias: NLK, SPU_010846, Spk149
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: nmo

Sequence

Name Sequence Type Origin Length Description Download
NLK.AA Protein None 390 None Fasta, JSON
NLK.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of NLK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NLK.AA nmo 31-285 77 3.7e-206 640.79 In-house 17-292 (292) Show / Hide 
Range on Protein: 31-285
Range on HMM: 17-292/292
Sequence Identity: 77% (216 aa)

SVTDPRDGKRVALKKMPHVFQNLISCKRVYRELKMLFFFNHDNSHFSGRNCLESLHK------YVVTELLQSDLHKIIVSPQPLSSDHVKVFLYQILRGL
|||||||||||||||||.|||||.|||||.||||||.||.||| ..|....|...||      ||||||.||||||||||||.|||||||||||||||||
SVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDN-VLSALDILQPPHKDFFQEIYVVTELMQSDLHKIIVSPQHLSSDHVKVFLYQILRGL

KYLHSAGILHRDI--------------VCDFGLARVEEPDTSKHMTQEVVTQYYRAPEILVGSKHYTSAVDMWSVGCIFAELLGRRILFQAQSPITQLNL
||||||.||||||              .||||||||.|.|.|||||||||||||||||||.|..|||||||.|||||||||||||||||||||||.||..
KYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELLGRRILFQAQSPIQQLQM

ITDLLGTPSMEDMKYACDGARAHLLRMPHKPPCLSALYGLSS--HATHEAVHLLSRMLVFNPDKRISCIDALAHPYL
|||||||||||||||||.||.||.||||||||||..||.|||  ||||||||||.|||.|.|||||||.||||||||
ITDLLGTPSMEDMKYACEGAKAHMLRMPHKPPCLQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAHPYL
Kinase NLK.AA MAPK 31-285 39 1.3e-132 446.81 In-house 17-328 (328) Show / Hide 
Range on Protein: 31-285
Range on HMM: 17-328/328
Sequence Identity: 39% (124 aa)

SVTDPR------DGKRVALKKMPHVFQNLISCKRVYRELKMLFFF-NHDNSHFSGRNCLES------LHK------YVVTELLQSDLHKIIVSPQPLSSD
|..| |      .||.||.||....|||...|||.|||.|.| .| .|.|   . ....         ..      |.|.|| ..|||.|| |.|||| |
SAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHEN-IIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMETDLHQIIKSQQPLSDD

HVKVFLYQILRG--LKYLHSAGILHRDI--------------VCDFGLARVEEPDTS-------------KHMTQEVVTQYYRAPEILVG--SKHYTSAV
|.. |.||||||  |||.|||...|||.              .|||||||...|...             .|||. |.|..||||||. .  ..||| ||
HIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAV

DMWSVGCIFAELLG-RRILFQAQSPITQLNLITDLLGTPSMEDMKYAC-DGARAHLLRMP--HKPPCLSALYGLSS----HATHEAVHLLSRMLVFNPDK
|||||||||||.|. |..||. ...| |.|||...|||||.|.... | . . .....    ....    .. . .    .|...|..||..||||.|||
DMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDK

RISCIDALAHPYL
||.  .||.|||.
RITVEEALQHPYF
Kinase NLK.AA CMGC 36-285 22 6e-93 305.74 In-house 36-513 (513) Show / Hide 
Range on Protein: 36-285
Range on HMM: 36-513/513
Sequence Identity: 22% (110 aa)

RDGKRVALKKMPHVFQNLISCK----------RVYRELKMLFFFN----------------HDNSHFSGRNCLESL------------------HKYVVT
.....||.||.  .| . . .|          | .||.|.|  .|                |.|   . .... .                   | | |.
ETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVF

ELLQSDLHKIIVSPQ---------PLSSDH------------VKVFL------YQILRGLK--YLHSAG--ILHRDI-----------------------
|... ||...| . |         |||  |            .| |.      ||||||||  |.||..  |.|||.                       
EYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSED

-----------VCDFGLAR-VEEP-------------------DTSKHMTQEVVTQYYRAPEILVGSKHYT---------SAVDMWSVGCIFAELLGR--
           .||||||| ....                   ......|..||| .|||||||.|.||||         ...|||||||||||.. .  
WNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQ

------RILFQ-----------AQSPITQLNLITDLLGTP----------------SMEDMKYAC---------------------DGARAHLLR---MP
      ..||.            .| | ||..| ..||||                . |.... .                     ..|| .. .    |
SLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFP

HKPP-CLSALYGLSSH--------------------------------ATHEAVHLLSRMLVFNPDKRISCIDALAHPYL
 .||  .. |.  ..                                 ....|..||..||...|||||.. .||.|||.
WWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase NLK.AA ERK5 36-285 38 1.9e-70 240.33 In-house 22-295 (295) Show / Hide 
Range on Protein: 36-285
Range on HMM: 22-295/295
Sequence Identity: 38% (108 aa)

RDGKRVALKKMPHVFQNLISCKRVYRELKMLFFFNHDN-----SHFSGRNCLESLHK-YVVTELLQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHS
. |..||.||.|  |  .   || .||||.|  | |||          .  .  ..  ||| .|. ||||.|| | ||.. .|.. |||||||||||.||
KNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQPFTLEHIRYFLYQILRGLKYMHS

AGILHRDI--------------VCDFGLARVEEP-DTSKH---MTQEVVTQYYRAPEILVGSKHYTSAVDMWSVGCIFAELLGRRILFQAQSPITQLNLI
| ..|||.              . |||.||      . ||   ||. | | .|||||... |. || |.|.||||||| |...|| .|  . .| ||.||
AQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIFGEMIARRQMFPGKNYIHQLQLI

TDLLGTPSMEDMK-YACDGARAHLLR--MPHKPPCLSALYGLSSHATHEAVHLLSRMLVFNPDKRISCIDALAHPYL
 . ||.|.   ..  . |  .... .   ...|  .. .|     |   |. ||.|||.| | .||.   || ||.|
MMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVY---PKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase NLK.AA ERK1 16-285 39 7.1e-69 235.13 In-house 2-289 (289) Show / Hide 
Range on Protein: 16-285
Range on HMM: 2-289/289
Sequence Identity: 39% (116 aa)

AKPMVAATRGLAIPGSVTDPRDGKRVALKKMPHVFQNLISCKRVYRELKMLFFFNHDN----SHFSGRNCLESLHK-YVVTELLQSDLHKIIVSPQPLSS
 .    .   ...  |  | . ..|||.||.   |     |.|  ||.|.|  |.|.|          . .|...  |.| .|.  || |.. . |.|| 
TNLQYIGEGAYGMVCSAYDTVHKQRVAIKKI-SPFEHQTYCQRTLREIKILTRFKHENIINIQDIIRADTIEQMRDVYIVQCLMETDLYKLLKT-QHLSN

DHVKVFLYQILRGLKYLHSAGILHRDI--------------VCDFGLARVEEPDTSK--HMTQEVVTQYYRAPEILVGSKHYTSAVDMWSVGCIFAELLG
||.  |||||||||||.||| .||||.              .|||||||. .|..     .|  | | .||||||.. || || ..|.|||||| ||.| 
DHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS

RRILFQAQSPITQLNLITDLLGTPSMEDMKYAC-DGARAHLLRMPHKPPCLSALYGLSSHATHEAVHLLSRMLVFNPDKRISCIDALAHPYL
 | .|  .  . |||.|  .|| || .|..    . ||. |  .||||    ..  |  .|   |. || .|| |||.|||   .|||||||
NRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKV--PWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase NLK.AA ERK7 32-285 34 4.2e-59 200.69 In-house 18-292 (292) Show / Hide 
Range on Protein: 32-285
Range on HMM: 18-292/292
Sequence Identity: 34% (95 aa)

VTDPRDGKRVALKKMPHVFQNLISCKRVYRELKMLFFFN-HDN--SHFSGRNCLESLHKYVVTELLQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLH
..| | .. |||||.   |.| .   | .||  .|  |. |.|  .          .  |.| | . .||| .|   . |   |... .||.|| .||.|
AYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRKGNILKDIHKQYIMYQLLRAIKYMH

SAGILHRDI--------------VCDFGLAR----VEE-PDTSKHMTQEVVTQYYRAPEILVGSKHYTSAVDMWSVGCIFAELLGRRILFQAQSPITQLN
|. ..|||.              ||||||||     ||  .    .|  | |  |||||||.||..|| .|||||.||| .|.|  . .|.  | . |..
SGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEMLRGKPMFPGTSTMNQIE

LITDLLGTPSMEDMKYACDGARAHLLRMPHKPPCLSALYGLSSHATHEAVHLLSRMLVFNPDKRISCIDALAHPYL
.| .... |..||..      .. .|   .       |  .  .. ..|. || |.|||||.||..  .||.||| 
KILETIPKPTQEDIEAIGSHYAWNMLEQMN-QQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase NLK.AA ERK 138-285 40 5.4e-52 179.06 In-house 149-307 (307) Show / Hide 
Range on Protein: 138-285
Range on HMM: 149-307/307
Sequence Identity: 40% (65 aa)

VCDFGLARVEEPDTSK-------HMTQEVVTQYYRAPEILVGSKHYTSAVDMWSVGCIFAELLGRRILFQAQSPITQLNLITDLLGTP-SMEDMKYA-CD
.|||||||..... ..       .||. |.| .||||||.   . ||.|.|.||.||||||.|||. ||.  . . |.|.|....||| | ||..|   .
ICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSE

GARAHLLRMPH--KPPC-LSALYGLSSHAT--HEAVHLLSRMLVFNPDKRISCIDALAHPYL
.|.  .  .|.  .||  .. ..   . |   ..|. ||..||||.|||||.  ..|.|||.
NAWKYIKNLPNPVRPPKPWENIF---PNANCNPQAIDLLEKMLVFDPDKRITVEECLEHPYF
Kinase NLK.AA CDK 140-285 35 8.1e-50 157.47 In-house 156-284 (284) Show / Hide 
Range on Protein: 140-285
Range on HMM: 156-284/284
Sequence Identity: 35% (58 aa)

DFGLARVEEP--D---TSKHMTQEVVTQYYRAPEILVGSKHYT--SAVDMWSVGCIFAELLG---RRILFQAQSPITQLNLITDLLGTPS------MEDM
||||||      .    .. .| ||||  |||||.| |||||.   ..|||||||||||..    |. ||. .| | || .| ...|||.      ....
DFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKL

KYACDGARAHLLRMPHKPPCLSALYGLSSHATHEAVHLLSRMLVFNPDKRISCIDALAHPYL
 .                                  .||..||...|.||||. .|| |||.
PDY---------------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase NLK.AA S_TKc 31-285 22 1.8e-48 168.26 SMART 17-231 (231) Show / Hide 
Range on Protein: 31-285
Range on HMM: 17-231/231
Sequence Identity: 22% (65 aa)

SVTDPRDGKRVALKKMPHVFQNLISCKRVYRELKMLFFFNHDNSHFSGRNCLESLHKYVVTELLQS---DLHKIIVSPQP------LSSDHVKVFLYQIL
 ... ..|..||.|...         ....||...|   .|.|       . .  | |.|.|..     ||...|.. ..      ..  |.. ..|||.
KCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQIC

RGLKYLHSAGILHRDI------------VCDFGLARVEEPDTSKHMTQEVVTQYYRAPEILVGSKHYTS-AVDMWSVGCIFAELLGRRILFQAQSPITQL
..|.|.|| ||.|||.            .|||||||.         |  ..| .|.|||.|    .|.  ..|.||.|||..|.| .. .|.      |.
CALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP------QM

NLITDLLGTPSMEDMKYACDGARAHLLRMPHKPPCLSALYGLSSHATHEAVHLLSRMLVFNPDKRISCIDALA-------HPYL
... ...|                                      ..|| ......|...|.||... .||.       ||..
QMMFKKIG--------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NLK.AA p38 140-285 41 2.8e-45 152.57 In-house 149-289 (289) Show / Hide 
Range on Protein: 140-285
Range on HMM: 149-289/289
Sequence Identity: 41% (61 aa)

DFGLARVEEPDTSKHMTQEVVTQYYRAPEILVGSKHYTSAVDMWSVGCIFAELLGRRILFQAQSPITQLNLITDLLGTPSMEDM-KYACDGARAHLLRMP
||||||     . . ||. |.|  ||||||.    ||| .||.|||||| |||. .|.||  . .| ||. |. ..|||. | . | . . ||. .  .|
DFGLAR----HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYP

HKPPCLSALYGLSSHATHEAVHLLSRMLVFNPDKRISCIDALAHPYL
  | .   .  . . |.  |. || .||.  |||||.  .|..|||.
QMPRR--DFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase NLK.AA MAPK-Unclassified 151-285 32 5.7e-39 135.8 In-house 401-575 (575) Show / Hide 
Range on Protein: 151-285
Range on HMM: 401-575/575
Sequence Identity: 32% (56 aa)

TSKHMTQEVVTQYYRAPEILVGSKHYTSAVDMWSVGCIFAELLGR-----------RILFQAQS--------------------PITQLNLITDLLGTPS
.. |||| ||| .||||||.  .. |. .||.||.||||||.. .           |.|| .|.                     . |...| | ||.| 
HCYHMTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPP

MEDMKY-ACDGARAHLLRMPHKPPC-LS-ALYGLSS------HATHEAVHLLSRMLVFNPDKRISCIDALAHPYL
 ||.    || ||  .     |.|   . . .   .          |.  ... ||.||| |||.  .|| ||| 
EEDCNFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase NLK.AA Pkinase 138-285 27 4.2e-34 121.66 Pfam 153-293 (293) Show / Hide 
Range on Protein: 138-285
Range on HMM: 153-293/293
Sequence Identity: 27% (42 aa)

VCDFGLARV-EEPDTSKHMTQEVVTQYYRAPEILVGSKHYTSAVDMWSVGCIFAELLGRRILFQAQ----SPITQLNLITDLLGTPSMEDMKYACDGARA
.||||||.. .    .  ||  ..| .|.|||.. |...|...|||||.|||..|.| .| .|. .    . ..|. .|   .|.| ..|  . |.. . 
ICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYF

HLLRMPHKPPCLSALYGLSSHATHEAVHLLSRMLVFNPDKRISCIDALAHPYL
. .|    .     .  .   .. |. ......| ..| ||... ..| ||..
F-FRH-W-H---F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase NLK.AA MAPK-Unclassified 33-136 41 3.1e-30 106.25 In-house 19-134 (575) Show / Hide 
Range on Protein: 33-136
Range on HMM: 19-134/575
Sequence Identity: 41% (49 aa)

TDPRD-GKRVALKKMPHVFQNLISCKRVYRELKMLFFFNHDNSHFSGRNCL--ESLHK------YVVTELLQS---DLHKIIVSPQ-PLSSDHVKVFLYQ
.| .  .. || || .|.|.| . |||| ||.  |   || |     .. .  ..||       |.|... |.   |||.|| |.| ...  |.. |.||
MDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPN-IIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIKSNQDHWCHQHIQYFFYQ

ILRGLKYLHSAGILHRD
|||||||||||.|.|||
ILRGLKYLHSACIIHRD
Kinase NLK.AA ERK 88-137 60 7.3e-26 92.25 In-house 85-134 (307) Show / Hide 
Range on Protein: 88-137
Range on HMM: 85-134/307
Sequence Identity: 60% (30 aa)

YVVTELLQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDI
|.|.|| ..|||.|| |.|.|| ||.. |.||||.||||.|||...|||.
YCVEELMETDLHQIINSQQELSDDHCQYFMYQILCGLKYIHSANVIHRDL
Kinase NLK.AA p38 88-136 57 8.5e-21 67.57 In-house 84-131 (289) Show / Hide 
Range on Protein: 88-136
Range on HMM: 84-131/289
Sequence Identity: 57% (28 aa)

YVVTELLQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRD
|.||.. ..||..|. . | || ||..  .||||||||| ||||| |||
YMVTHFMGADLNNIMKC-QRLSDDHIQFLVYQILRGLKYIHSAGIIHRD
Kinase NLK.AA CDK 90-137 37 2.3e-14 42.23 In-house 96-134 (284) Show / Hide 
Range on Protein: 90-137
Range on HMM: 96-134/284
Sequence Identity: 37% (18 aa)

VTELLQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDI
| | .  || |..          .| ...|.|||| |.|| .|.|||.
VFEYMDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDL
Kinase NLK.AA Pkinase 88-137 38 6.1e-13 46.85 Pfam 76-134 (293) Show / Hide 
Range on Protein: 88-137
Range on HMM: 76-134/293
Sequence Identity: 38% (23 aa)

YVVTELLQS-----DLHKIIV--SPQPL--SSDHVKVFLYQILRGLKYLHSAGILHRDI
|.|.|...      ||. .|   .  ..  | ...| ..|||||||.|.|| ||.|||.
YMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDL
Kinase NLK.AA ERK 31-73 38 2.6e-10 34.79 In-house 17-65 (307) Show / Hide 
Range on Protein: 31-73
Range on HMM: 17-65/307
Sequence Identity: 38% (19 aa)

SVTDPR-----DGKRVALKKMPHVFQNLISCKRVYRELKMLFFFN-HDN
|..|       .|..|| || . .| ..| ||| .||.|.| .|. |.|
SAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHEN
Kinase NLK.AA p38 31-73 41 8.4e-09 25.92 In-house 17-62 (289) Show / Hide 
Range on Protein: 31-73
Range on HMM: 17-62/289
Sequence Identity: 41% (19 aa)

SVTDPRDGKR---VALKKMPHVFQNLISCKRVYRELKMLFFFNHDN
.. | | |..   || ||.   ||  |  || ||||. |   .|.|
KAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHEN
TyrKc NLK.AA TyrKc 6-280 15 1.3e-08 -83.23 SMART 1-280 (280) Show / Hide 
Range on Protein: 6-280
Range on HMM: 1-280/280
Sequence Identity: 15% (53 aa)

ERLGTK---------ERGVAKPMVAATRGLAIPGSVTDPRDGKRVALKKMPHVFQNLISCKRVYRELKMLFFF--NHDN-------SHFSGRNCLESLHK
 .|| |          .|..|                       || |.. .        .  .||....  .  .|.|          .||| ...   
ITLGKKLGEGAFGEVYKGTWK---------------------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPL

YVVTELLQS-DLHKIIVSPQP-LSSDHVKVFLYQILRGLKYLHSAGILHRDI--------------VCDFGLARVEEPD-------TSKHM-----TQEV
..|.|.    ||.. . ...| |. ..   | .|| .|  |||| .. |||.              ..||||.|  . |         ...     .  .
MIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTM

VTQYYRAPEILVGSKHYTSAVDMWSVGCIFAELLGRRILFQAQ------SPITQLNLITDLLGTPSMED---MKYACDGARAHLLRMPHKPPCLSALYGL
.     ||| .   . .|.. | || |    |.. .             |..  .... .    | ...   |                           
LPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------

SSHATHEAVHLLSRMLVFNPDKRIS---CIDAL
. ... |   . ..   ..|..| .   ... .
FVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase NLK.AA Pkinase_Tyr 88-137 30 0.000649 13.88 Pfam 83-137 (270) Show / Hide 
Range on Protein: 88-137
Range on HMM: 83-137/270
Sequence Identity: 30% (17 aa)

YVVTELLQS-DLHKIIVS----PQPLSSDHVKVFLYQILRGLKYLHSAGILHRDI
|.|.|. .  ||..   .    .|||.  .   . .|| .|. ||.| .. |||.
YIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase NLK.AA Pkinase_Tyr 138-184 32 6.911374 0.24 Pfam 152-199 (270) Show / Hide 
Range on Protein: 138-184
Range on HMM: 152-199/270
Sequence Identity: 32% (16 aa)

VCDFGLARVE-EPDTS-KHMTQEVVTQYYRAPEILVGSKHYTSAVDMWS
.|||||||   . |.  .  .   .     ||| .  .| .|.. | ||
ICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWS