Gene CDK5 (Sea Urchin)

CDK5

Species: Sea Urchin
Alias: SPU_017705, CDK5, Spk130
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK5

Sequence

Name Sequence Type Origin Length Description Download
CDK5.AA Protein None 242 None Fasta, JSON
CDK5.kin_dom Protein Kinase Domain None 182 None Fasta, JSON

Protein domain

Protein domains of CDK5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CDK5.AA CDK5 53-234 75 1.7e-154 491.95 In-house 102-287 (287) Show / Hide 
Range on Protein: 53-234
Range on HMM: 102-287/287
Sequence Identity: 75% (140 aa)

SFMYQLLRGLAFCHSHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKVYTTSIDMWSAGCIFAEMANAGRPLFP
|||||||.||||||.||||||||||||||||||||||||||||||||||||||||.|||||||||||||.|.|.|.|||||||.||||||||||||||||
SFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLFP

GNDVEDQLKRIFKLLGTPTEDTWPGISKLPDFK----PYPIYPVTTPLASVVPSLSATGRDLLQRLMMCNPALRMSAEEGLMHQYF
|||||||||||||..|||.||.||.|.||||.|    .||.||........||.|...|.||||....|||. |.||...|.|.||
GNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase CDK5.AA CDK 53-234 51 4.8e-121 389.06 In-house 112-284 (284) Show / Hide 
Range on Protein: 53-234
Range on HMM: 112-284/284
Sequence Identity: 51% (101 aa)

SFMYQLLRGLAFCHSHHVLHRDLKPQNLLINKNGE-----LKLADFGLARAFGI------PVRCYSAEVVTLWYRPPDVLFGAKVYT--TSIDMWSAGCI
..|.||||||..|||....||||||||.|||.|||     ||.|||||||||||      |.|.|. ||||||||.|..|.|.| |.  |.|||||.|||
CYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCI

FAEMAN--AGRPLFPGNDVEDQLKRIFKLLGTPTEDTWPGISKLPDFKPYPIYPVTTPLASVVPSLSATGRDLLQRLMMCNPALRMSAEEGLMHQYF
||||..  ...|||||.   |||..||...||||||.|||..||||.                        |||.......|. |.|||. | |.||
FAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CDK5.AA CDC2 53-234 51 1.6e-102 315.91 In-house 107-301 (301) Show / Hide 
Range on Protein: 53-234
Range on HMM: 107-301/301
Sequence Identity: 51% (100 aa)

SFMYQLLRGLAFCHSHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYS--AEVVTLWYRPPDVLFGAKVYTTSIDMWSAGCIFAEM-AN-AGR
|.|||.|.|..|||.. ..||||||||.||.|.|..|.||||||||||||.| |    ||||||||.| .|.|.| |.|..|||| |||||||  .   .
SYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKK

PLFPGNDVEDQLKRIFKLLGTPTEDTWPGISKLPDFKP-YPIYPVTTPLASVVPS---------LSATGRDLLQRLMMCNPALRMSAEEGLMHQYF
|||.|    ||| .||. ||||.|.||||...|||.|. .| .. .. | ...|.         |  .|.|||...   .|. | ||.| | | ||
PLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWK-PQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase CDK5.AA PFTAIRE 54-234 55 4e-99 335.63 In-house 102-287 (287) Show / Hide 
Range on Protein: 54-234
Range on HMM: 102-287/287
Sequence Identity: 55% (103 aa)

FMYQLLRGLAFCHSHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKVYTTSIDMWSAGCIFAEMANAGRPLFPG
|..||||||..||  .||||||||||||| . |||||||||||||  .| . || ||||||||||||| |.  | |..||| .|||| ||  .|.|.|||
FLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMM-WGQPAFPG

N-DVEDQLKRIFKLLGTPTEDTWPGISKLPDFKPYPIY---PVTTPLASVVPSLS--ATGRDLLQRLMMCNPALRMSAEEGLMHQYF
  |. ||| .|||.|||||||||||...|| .||. .    .   .|  ..|...  . . ||.. .. |.|  |.||.| . |.||
MKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase CDK5.AA CDK7 53-234 46 4.9e-98 261.67 In-house 106-288 (288) Show / Hide 
Range on Protein: 53-234
Range on HMM: 106-288/288
Sequence Identity: 46% (86 aa)

SFMYQLLRGLAFCHSHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKVYTTSIDMWSAGCIFAEMANAGRPLFP
..| ..|.|| .|| . .||||||| |||.|.||.||.|||||||..| | | |.  ||| ||| |  ||||. |.|..|||| ||||||      | .|
AYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELM-LRVPYLP

GNDVEDQLKRIFKLLGTPTEDTWPGISKLPDFKPYPIYPVT--TPLASVVPSLSATGRDLLQRLMMCNPALRMSAEEGLMHQYF
|    |||.|||. |||||| .||......|.    ..|    |||  .    |    ||....   ||  |... . | . ||
GDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase CDK5.AA CMGC 53-234 28 3.3e-97 319.97 In-house 178-513 (513) Show / Hide 
Range on Protein: 53-234
Range on HMM: 178-513/513
Sequence Identity: 28% (96 aa)

SFM------YQLLRGLA--FCHSHH--VLHRDLKPQNLLINKNGEL--------------------KLADFGLARAFGIP--------------------
.||      ||.||||.  .||||   ..||||||.|.|||.|.||                    |..||||||.....                    
YFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDK

-VRCYSAEVVTLWYRPPDVLFGAKVYT---------TSIDMWSAGCIFAEMANA-------GRPLFPGNDV-----------EDQLKRIFKLLGTPT---
 .| |. .|||.|||.| .|.|.| ||         |.|||||.||||||| .        |.|||||..             |||..|||.|||||   
PNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMI

------------EDTWPGISKLPDFKP-------------YPI-----------YPVTT--PLASVVPS-------------------------------
            |..||...|||....             ...           .|     |. ...|                                
QKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQF

----LSATGRDLLQRLMMCNPALRMSAEEGLMHQYF
    ..  ..|||.... ..|. |..||. | | ||
KRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CDK5.AA PCTAIRE 54-234 55 1.1e-95 324.25 In-house 102-291 (291) Show / Hide 
Range on Protein: 54-234
Range on HMM: 102-291/291
Sequence Identity: 55% (106 aa)

FMYQLLRGLAFCHSHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKVYTTSIDMWSAGCIFAEMANAGRPLFPG
|..|||||||.||   .|||||||||||||  |||||||||||||  .| . || ||||||||||||| |   | |.||||  ||||.||. .|||||||
FLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMC-TGRPLFPG

ND------VEDQLKRIFKLLGTPTEDTWPGISKLPDFKPY--PIYPVTTPLASVVPSLS---ATGRDLLQRLMMCNPALRMSAEEGLMHQYF
        |.|||  ||..||||.| ||||.. ...|..|  | |.   || .. | |     .. |||. |.   .  |.|||. . | ||
STDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYR-EQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase CDK5.AA PITSLRE 53-234 46 1.4e-77 264.1 In-house 110-295 (295) Show / Hide 
Range on Protein: 53-234
Range on HMM: 110-295/295
Sequence Identity: 46% (87 aa)

SFMYQLLRGLAFCHSHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKVYTTSIDMWSAGCIFAEMANAGRPLFP
..| ||||| .. |.. ..|||||  |||.. .| ||..|||||| .| |.. |.  ||||||| | .| |.|.|.| .|||| ||||||.   ..|||.
CLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEFI-TMKPLFQ

GNDVEDQLKRIFKLLGTPTEDTWPGISKLPDFKPYP---IYPVTTPLASVVP---SLSATGRDLLQRLMMCNPALRMSAEEGLMHQYF
|.   ||...|||..|||||  |||...|| .|       ||    | . .|    .| || |||...   ||. |..|...| | .|
GKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYP-YNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase CDK5.AA CDK4 55-234 47 7.4e-69 235.08 In-house 116-290 (290) Show / Hide 
Range on Protein: 55-234
Range on HMM: 116-290/290
Sequence Identity: 47% (87 aa)

MYQLLRGLAFCHSHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKVYTTSIDMWSAGCIFAEMANAGRPLFPGN
| |||||. | ||| . ||||||||.|.. .|..||||||||| ..      .  ||||||| | ||  .  | | .||||.||||||| .  ||||.|.
MHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQMALTPV-VVTLWYRAPEVLL-QSYYNTPVDMWSVGCIFAEMYCR-RPLFCGQ

DVEDQLKRIFKLLGTPTEDTWPGISKLP--DFKPYPIYPVTTPLASVVPSLSATGRDLLQRLMMCNPALRMSAEEGLMHQYF
   ||| .||.. |.|.|| ||  . ||   |...      .|. ...| ..  | ||||.    |...||||...| | ||
SEKDQLHKIFDVMGLPPEDDWPRDVSLPWDHFPQR----HPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase CDK5.AA Pkinase 54-234 35 2.6e-60 211.48 Pfam 113-293 (293) Show / Hide 
Range on Protein: 54-234
Range on HMM: 113-293/293
Sequence Identity: 35% (67 aa)

FMYQLLRGLAFCHSHHVLHRDLKPQNLLINKNGEL----KLADFGLARAF-GIPVRCYSAEVVTLWYRPPDVLFGAKVYTTSIDMWSAGCIFAEMANAGR
.|||.||||..|||. ..||||||.|.||..||..    |..|||||. |   . . ..  ..|.||..| |. |.. |....||||.|||..||.. ||
YMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GR

PLFPGN----DVEDQLKRIFKLLGTPTEDTWPGISKLPDFKPYPIYPVTTPLASVVPSLSATGRDLLQRLMMCNPALRMSAEEGLMHQYF
|.|||     .  ||...|.. .|.|..  ||  .  ..|.  .. . .. .  . . .| ...|.. ..   .|. | .||. | | .|
PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CDK5.AA CRK7 53-185 36 4.9e-52 177.67 In-house 116-287 (343) Show / Hide 
Range on Protein: 53-185
Range on HMM: 116-287/343
Sequence Identity: 36% (63 aa)

SFMYQLLRGLAFCHSHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPV--RCYSAEVVTLWYRPPDVLFGAKVY-----------------------
.|| ||| |.. ||   .||||.|  |.|.| .||.|.||||||| .      | |   |.|||||||  | |.. |                       
CFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKELIRNIKSIQLSLLIS

---------------TTSIDMWSAGCIFAEMANAGRPLFPGNDVEDQLKRIFKLLGTPTEDTWPGISKLPDFK
               ...||||| |||..| .. ..|.|.||   .||  |.|. |.|. . || . ||| ..
IYLKLTVQSSIFKKSGPEIDMWSCGCILGELFT-KKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWN
Kinase CDK5.AA S_TKc 18-234 22 6.9e-41 143.07 SMART 1-231 (231) Show / Hide 
Range on Protein: 18-234
Range on HMM: 1-231/231
Sequence Identity: 22% (64 aa)

YTTAER----TYGTVFKAKNRETQEIVALKRVR----------------------------------------------LDDDDE------------SFM
|.  .     ..|.|.|.....|..|||.|...                                              ...               ..|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM

YQLLRGLAFCHSHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKVYTT-SIDMWSAGCIFAEMANAGRPLFPGN
||....|..||||...||||||.|.|...  ..|..|||||| .       .  ..|.||..| ||     |.. ..|.|| |||..||.  |.|.||  
YQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC-GYPPFP--

DVEDQLKRIFKLLGTPTEDTWPGISKLPDFKPYPIYPVTTPLASVVPSLSATGRDLLQRLMMCNPALRMSAEEGLM-------HQYF
    |....||..|                                   |  ..|......  .|. |..| | |        |..|
----QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CDK5.AA CDK5 24-52 79 1.9e-17 51.27 In-house 11-39 (287) Show / Hide 
Range on Protein: 24-52
Range on HMM: 11-39/287
Sequence Identity: 79% (23 aa)

TYGTVFKAKNRETQEIVALKRVRLDDDDE
|||||.||.|.||.|||||||||||..||
TYGTVYKARNKETHEIVALKRVRLDSEDE
Kinase CDK5.AA CDC2 18-52 46 1.1e-12 34.81 In-house 1-39 (301) Show / Hide 
Range on Protein: 18-52
Range on HMM: 1-39/301
Sequence Identity: 46% (18 aa)

YTTAER----TYGTVFKAKNRETQEIVALKRVRLDDDDE
|.  |.    ||| |.|.|...|..|||||..||. .||
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDE
Kinase CDK5.AA CDK 24-52 35 1.7e-12 36.12 In-house 11-49 (284) Show / Hide 
Range on Protein: 24-52
Range on HMM: 11-49/284
Sequence Identity: 35% (14 aa)

TYGTVFKAKNRETQ-----EIVALKRVRLDD-----DDE
|||.|.||....|.     .|||||..|..      ..|
TYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKE
Kinase CDK5.AA CRK7 24-52 56 5.3e-11 33.97 In-house 11-42 (343) Show / Hide 
Range on Protein: 24-52
Range on HMM: 11-42/343
Sequence Identity: 56% (18 aa)

TYGTVFKAKNRETQEIVALKRVRLDDD---DE
||| | |||| .| |.||||.||.|..    |
TYGQVYKAKNKHTGEMVALKKVRMDNEKIKKE
Kinase CDK5.AA CMGC 24-52 30 8.4e-09 24.09 In-house 11-52 (513) Show / Hide 
Range on Protein: 24-52
Range on HMM: 11-52/513
Sequence Identity: 30% (13 aa)

TYGTVFKAKN--------------RETQEIVALKRVRLDDDDE
|||.|.|...              .||.||||.|.....  .|
TYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YE
Kinase CDK5.AA PITSLRE 15-48 44 1.4e-08 27.57 In-house 2-35 (295) Show / Hide 
Range on Protein: 15-48
Range on HMM: 2-35/295
Sequence Identity: 44% (15 aa)

KEYYTTAERTYGTVFKAKNRETQEIVALKRVRLD
.  .. .| ||| |..||...| |||||||. ..
QCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKME
Kinase CDK5.AA CRK7 209-234 42 3e-06 17.33 In-house 318-343 (343) Show / Hide 
Range on Protein: 209-234
Range on HMM: 318-343/343
Sequence Identity: 42% (11 aa)

DLLQRLMMCNPALRMSAEEGLMHQYF
|||  ..  .|  |..||| | |..|
DLLDKMLCLDPKKRFTAEECLQHDWF
Kinase CDK5.AA CDK7 15-47 32 8e-06 10.97 In-house 2-35 (288) Show / Hide 
Range on Protein: 15-47
Range on HMM: 2-35/288
Sequence Identity: 32% (11 aa)

KEYYTTAERTYGTVFKAKNRETQEIVALKRVR-L
.      | ...||.||   .| .||| |... |
EKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKL
Kinase CDK5.AA Pkinase_Tyr 53-98 36 1.1e-05 19.85 Pfam 115-160 (270) Show / Hide 
Range on Protein: 53-98
Range on HMM: 115-160/270
Sequence Identity: 36% (17 aa)

SFMYQLLRGLAFCHSHHVLHRDLKPQNLLINKNGELKLADFGLARA
.. .|  .|... .|..  ||||   | |...|.  | .||||||.
QMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase CDK5.AA TyrKc 19-234 16 2e-05 -135.04 SMART 1-280 (280) Show / Hide 
Range on Protein: 19-234
Range on HMM: 1-280/280
Sequence Identity: 16% (53 aa)

TTAERT-----YGTVFKAKNRETQEIVALKRVR----------------L---------------DD---------------------------DDE---
 | ...     .|.|.|.. .   . || | ..                |               ..                           . .   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

------SFMYQLLRGLAFCHSHHVLHRDLKPQNLLINKNGELKLADFGLARAF--------------------G---IPVRCYSAEVVTLWYRPPDVLFG
      ||..|  .| .. ||... ||||   | |...|.  | .||||.|.                     |   .|.| .. |.             
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----------N

AKVYTTSIDMWSAGCIFAEMANAGRPLFPG--------NDVEDQLKRIFKLLGTPT-EDTWPGISKLPDFKPYPIYPVTTPLASVVPSLSATGRDLLQRL
 ...||  | || |    |.   | .  ||         .|  ..|. . .   |  .   | .|                        . .  | . ..
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---P-MS------------------------FVCCPDEMYQI

MMC----NPALRMSAEEGLMHQYF
| .    .|. | . .|   |..|
MKQCWHEDPEDRPTFSEI--HECF
Kinase CDK5.AA Pkinase 24-53 26 2.4e-05 20.0 Pfam 11-40 (293) Show / Hide 
Range on Protein: 24-53
Range on HMM: 11-40/293
Sequence Identity: 26% (8 aa)

TYGTVFKAKNRETQEIVALKRVRLDDDDES
..|.|.|.... |..|||.|..........
SFGCVYKCHHKGTGKIVAVKIIKKRHEKSW
Kinase CDK5.AA PCTAIRE 22-48 48 7.3e-05 13.0 In-house 9-35 (291) Show / Hide 
Range on Protein: 22-48
Range on HMM: 9-35/291
Sequence Identity: 48% (13 aa)

ERTYGTVFKAKNRETQEIVALKRVRLD
| || ||.| . . |  .|||| .||.
EGTYATVYKCRSKLTDNLVALKEIRLE
Kinase CDK5.AA CDK4 25-52 46 0.000115 11.69 In-house 12-39 (290) Show / Hide 
Range on Protein: 25-52
Range on HMM: 12-39/290
Sequence Identity: 46% (13 aa)

YGTVFKAKNRETQEIVALKRVRLDDDDE
||||..|   .|  .||||.||    .|
YGTVYRARDLHTGHFVALKQVRIPIGEE
Kinase CDK5.AA PFTAIRE 22-50 41 0.000214 11.37 In-house 9-37 (287) Show / Hide 
Range on Protein: 22-50
Range on HMM: 9-37/287
Sequence Identity: 41% (12 aa)

ERTYGTVFKAKNRETQEIVALKRVRLDDD
| .| ||.|.. . .| .|||| .||...
EGSYATVYKGISCINQQFVALKEIRLQQE