Gene 3655 (Tetrahymena)

3655

Species: Tetrahymena
Alias: 3655, PreTt03655, 96.m00124, TTHERM_00655570, 6
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
3655.AA Protein None 418 None Fasta, JSON
3655.NA RNA None 1257 None Fasta, JSON
3655.kin_dom Protein Kinase Domain None 278 None Fasta, JSON

Protein domain

Protein domains of 3655.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 3655.AA AGC 22-299 24 3.2e-123 320.06 In-house 1-395 (395) Show / Hide 
Range on Protein: 22-299
Range on HMM: 1-395/395
Sequence Identity: 24% (104 aa)

FYFHFVIGRGGFGKVWKVESK------KQKQLYALKEMSKSK-IISKR--SVQSVMNE------------KQLLSSLR----------HDFLIN-MIYAF
| |. |||.|.||||. |. |        ...||.| ..|.. |. |.   |. .|.|            .. |. ..          |.|... . |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

SDRSN--LYLVMDLLT---------GG-DLRFHIS---RHRRFTEQQTKFFAAC-------IVVGLEYLHQ-NGILHRD-IKPENLVFDNKGYLRITDLG
 | ..  ||.||...          || .| .|.    . .||.|....|.||.       || .|||||. .|| ||| .||||...|..|....|| |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

IARI--------------------------------------WKPEN--------------SSDTSG--TPGYMAPEVMCRQNHGVAVDYYA--LGIIVY
 . .                                      |. .|               .   |  || |||||.     .| |.|...  ||.. |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ECMMGRRPYLGRTRQ----------EIRDQILARQVQIKKSEVP-----------DKWSLEAADFCNRVRKNLQVYQDKQKYFFQKQLIQRKPMNRLG-L
| . |. |. | ..|          |. ..|. ... |.. .             ...| || |....                   |... | .||| .
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKK-------------------LLCKDPEKRLGCG

N------GPEEVKNHPWF
.      | ||.||||||
GNDFGDKGAEEIKNHPWF
Kinase 3655.AA Ciliate-E2-Unclassified 22-299 30 5e-116 391.78 In-house 1-352 (352) Show / Hide 
Range on Protein: 22-299
Range on HMM: 1-352/352
Sequence Identity: 30% (113 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLYALKEMSKSKIISKRSVQSV---------MNEKQ-------------LLSSLRHDFLINMIYAFSDRSNLYLVM
. .. .||.||||||.|.. |||||.||.|.|.|..|.........         ||.|.             .|... | |...|.|.| |. |.|.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

DLLTGGDLRFHIS----------------RH-RRFTEQQTK-----FFAACIVVGLEYLHQNG-ILHRDIKPENLVFDNKG---YLRITDLGIAR-----
... ||||...|.                .. ..|||||.|     |..|.|..||||||... |.||||||||..|||.|   |..|.|.||..     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------IWKPENSSDTSGTPGYM----APEVMCRQNHG----VAVDYYALGIIVYECMMGRRPYLGRTRQE----------------IRDQILA
            |||........|||.||    ||||...||..     ..|...||.| ||...|..|. .... .                ....|..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

RQVQIKKSE---VPDKWSLEAADFCNRVRKNLQVYQDKQKYFFQKQLIQRKPMNRLGLN-GPEEVKNHPWF
...|..|..   .|..|| ||.||.|                   .|.|... .... . ..|...|||||
KNIQFPKFPWQQIPKHWSPEAKDFIN-------------------DLLQKMLKKNPNKRITFEQILNHPWF
Kinase 3655.AA Ciliate-E2 22-299 25 1.6e-95 323.61 In-house 1-365 (365) Show / Hide 
Range on Protein: 22-299
Range on HMM: 1-365/365
Sequence Identity: 25% (100 aa)

FYFHFVIGRGGFG-----KVWKVES------------------KKQKQLYALKEMSKSKIISKRSVQSVM----------NEKQLLSSLRHDFLINMIYA
. |. .||.|.||     |||||                    | ....||.| |.|..|... .....|          |||..|..| |...|.|...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FS--DRSNLYLVMDLLTGGDLRFHIS------------------RHRR-FTEQQTK-------FFAACIVVGLEYLHQNG-ILHRDIKPENLVFDNKGYL
|   |..|.||||... ||||. .|                   .... ...|...       |..|||...|||||... |.||||||||..|     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RITDLGIARI---------------WKPENSSDT-------------------SGTPGYMAPEVMCRQN---------HGVAVDYYALGIIVYECMMGRR
 |.|.|....               |... ..||                    |||||||||.  ...         .. ..|...||.| ||...|..
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYLGRTRQEIRDQILARQVQIKKSE-------------VPDKWSLEAADFCNRVRKNLQVYQDKQKYFFQKQLIQRKPMNRLGLNGPEEVKNHPWF
|.         .||.  .... . |              ..|||.|. |.... . . .            ...|..| .|..  |.|...|||||
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKK-F-G-K------------RMLQKDPEKRIT--GWEQILNHPWF
Kinase 3655.AA S_TKc 22-299 27 8e-81 275.74 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-299
Range on HMM: 1-231/231
Sequence Identity: 27% (79 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLYALKEMSKSKIISKRSVQSVMNEKQLLSSLRHDFLINMIYAFSDRSNLYLVMDLLTG--GDLRFHISRHRR---
. .. .||.|.||||.|.  || ....|.|...          .....| |.|.. .|.........| | ..||.||... |  |||. .| ...|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTEQQTKFFAACIVVGLEYLHQNGILHRDIKPENLVFDNKGYLRITDLGIARIWKPENSSDTSGTPGYMAPEVMCRQNHGV-AVDYYALGIIVYECM
   |.| ...|... |. .|||.|..||.|||.||||. .|.   . |.| |.||.      .   ||| ||||||.    .|  ..| ...|.|.||..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

MGRRPYLGRTRQEIRDQILARQVQIKKSEVPDKWSLEAADFCNRVRKNLQVYQDKQKYFFQKQLIQRKPMNRLGLNGPEE----VKNHPWF
 |. |.   . |.. ..|.                                  ...   | ... |. | .|..     .    .|.||||
CGYPPFP--QMQMMFKKIG----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 3655.AA Akt 22-299 33 2.6e-77 246.69 In-house 1-264 (264) Show / Hide 
Range on Protein: 22-299
Range on HMM: 1-264/264
Sequence Identity: 33% (97 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLY-ALKEMSKSKIISKRSVQSVMNEKQLLSSLRHDFLINMIYAFSDRSNLYLVMDLLTGGDLRFHISRHRRFTEQ
|.|  |.|.| ||||  |. |. ...| |.|  .|..|| |. |. .. |. .|   .| |..|. |.| .  .||.|||   ||.| .|..| |||.|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

QTKFFAACIVVGLEYLHQNGILHRD-IKPENLVFDNKGYLRITDLGIAR-I-WKPENSSDT-SGTPGYMAPEVMCRQNHGVAVDYYA-LGIIVYECMMGR
...|..| |. ..|.||...|  ||  ||||.. |..|....|| | .. .  |     .|  ||| |.|||.   . |. ||| .. ||.. || | ||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

RPYLGRTRQEIRDQILARQVQIKKSEVPDKWSLEAADFCNRVRKNLQVYQDKQKYFFQKQLIQRKPMNRLG--LNGPEEVKNHPWF
 |.  . ...  ..|.  .|....    |..| |. |. ..                   | .. | .|||   |. .|.|.||||
PPFYNQDHHQMFKKIKNQPVKFPDK---DWISPECKDLISG-------------------LLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 3655.AA SGK 22-248 35 2.1e-73 225.9 In-house 1-255 (283) Show / Hide 
Range on Protein: 22-248
Range on HMM: 1-255/283
Sequence Identity: 35% (90 aa)

FYFHFVIGRGGFGKVWKVESKKQ------------------KQLYALKEMSKSKII-------SKRSVQSVMNEK-QLLSSLRHDFLINMIYAFSDRSNL
| |  ||| |.||||  |. |.                   ...||.|  .|  ||        | ..  .| |.  .|. ..| |..|  |||     |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLVMDLLTGGDLRFHISRHRRFTEQQTKFFAACIVVGLEYLHQNGILHRDIKPENLVFDNKGYLRITDLGIAR--IWKPENSSDTSGTPGYMAPEVMCRQ
|.||| . ||.. .|. | ..| | . .| || ||  |||||   | .|| ||||.. | .|....|| | .   | . .  .   ||| |.||||.  |
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

NHGVAVDYYALGIIVYECMMGRRPYLGRTRQEIRDQILARQVQIKKSEVPDKWSL
 |. .|| . ||.. || |.|  |.  | .|.  |.|.    ||...  .| |.|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDL
Kinase 3655.AA AktR 22-299 31 2.2e-70 240.16 In-house 1-268 (268) Show / Hide 
Range on Protein: 22-299
Range on HMM: 1-268/268
Sequence Identity: 31% (90 aa)

FYFHFVIGRGGFGKVWKVESK-KQKQLYALKEMSKSKIISKRSVQSVMNEKQLLS-SLRHDFLINMIYAFSDRSNLYLVMDLLTGGDLRFHISRHRRFTE
| .. ..|.|.||||  |. | . ...||.|  .|.||| ..  . . .|.. .    .| |.... |.| ....|...|.   ||.| .|... ..|.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

QQTKFFAACIVVGLEYLHQN-GILHRDIKPENLVFDNKGYLRITDLGIAR--IWKPENSSDTS--GTPGYMAPEVMCR-QNHGVAVDYYALGIIVYECMM
.|..|..| |. .||||||.  |  ||.||||.. |  |...||| | ..  . . ..   .|  ||| |||||.  . . |. .||..|.|| .|| ..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GRRPYLGRTRQEIRDQILARQ-VQIKKSEVPDKWSLEAADFCNRVRKNLQVYQDKQKYFFQKQLIQRKPMNRLG--LNGPEEVKNHPWF
|  |     .... . |.  | .......   . | .. |...|                  .| .. | .|||   ||.||.|.||||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPS---YFSSQCKDLIQR------------------KLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 3655.AA Pkinase 22-256 29 5e-67 233.79 Pfam 1-272 (293) Show / Hide 
Range on Protein: 22-256
Range on HMM: 1-272/293
Sequence Identity: 29% (82 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLYALKEMSKSKIISKRSVQSVM-NEKQLLSSLRHDFLINMIYAFSDRSNLYLVMDLLTGG----DLRFHIS--RH
. .. .||.|.||.|.|   |.  ...|.|...|... |.  .. .  .| |.. .|.|.. . ....| |....|.||... ||    ||  .||  ||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RRF--TEQQTKFFAACIVVGLEYLHQNGILHRDIKPENLVFDNKGYL----RITDLGIAR---IWKPENSSDTSGTPGYMAPEVMC-RQNHGVAVDYYAL
..|  .|.. ||..  |. ||||.|..||.|||.||||. .||.|..    .|.| |.|.   . . .  ..  |||.||||||   .| .| .|| ...
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIIVYECMMGRRPYLGR------TRQEIRDQILARQVQIKKSEVPD----------------KWSLEAADFCNR
|.|.|| . || |. |.      . ... ..|. ...    ..  .                .|| |. ||...
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW
Kinase 3655.AA CAMK 27-253 18 1.6e-63 203.29 In-house 1-401 (425) Show / Hide 
Range on Protein: 27-253
Range on HMM: 1-401/425
Sequence Identity: 18% (73 aa)

VIGRGGFGKVWKVESKKQK------------QLYALKEMSKSKIIS-------------------------KRSVQSVMNEKQLLSS-------LRHDFL
..|||.|||| ... |. .            | .| | ..|.|. .                          .. ..|..| .....       |.|  .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

INMIYAFSD-------------------RSNLYLVM---DLLTGG----DLRFHISRH---------------RRFTEQQTKFFAACIVVGLEYLHQNGI
|... .. |                   ....|.||   .. .||    ||  .| .|               .||||......   |. ...|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDIKPENLVFDNKG----------------Y-LRITDLGIARIWKPEN-------------------------SSDTSGTPGYMA-PEVMCRQN----
 |||.||||. .|...                . . |.| | |.. .| .                          ..  |||.||| |||  ..     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------HGVAVDYYALGIIVYECMMGRRPYLGRTRQEIRD---------QILARQVQIKKSEVPDKWSL-----------------------EAAD
          .| ..|  ..|.| | .  |. |. | ...||..         ... .  . | .  |...|                        |. |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

F
.
L
Kinase 3655.AA RSK 25-231 33 6.6e-62 211.99 In-house 1-228 (278) Show / Hide 
Range on Protein: 25-231
Range on HMM: 1-228/278
Sequence Identity: 33% (76 aa)

HFVIGRGGFGKVWKVESK---KQKQLYALKEMSKSKIISK-RSVQSVMNEKQLLSSLR-HDFLINMIYAFSDRSNLYLVMDLLTGGDLRFHISRHRR---
. | |.||.|||  .  .   ...|.|| |  .|.||. . ...  .| | . |.  . | |...  ||| . . |||.|... ||.|  |......   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTEQQTKFFAACIVVGLEYLHQNGILHRDIKPENLVFDN---KGYLRITDLGIARIWKPENSSDTS---GTPGYMAPEVMC---RQN-HGVAVDYYALGI
|.|   .| .| ||. .|.||| || |||.|||| ..|.    | ...|| | ... ...... |    .|  |||||.     .|. |. |.|.. ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

IVYECMMGRRPYLG---RTRQEIRDQIL
. ||  .|..|. |    .|.|| ..|.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQ
Kinase 3655.AA PKA 22-217 37 2.4e-57 196.85 In-house 1-198 (263) Show / Hide 
Range on Protein: 22-217
Range on HMM: 1-198/263
Sequence Identity: 37% (75 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLYALKEMSKSKIISKRSVQSVMNEKQLLSSLRHDFLIN-MIYAFSDRSNLYLVMDLLTGGDLRFHISRHRRFTEQ
| .  ..|.| ||.|  . .|. .. ||.| ..|..|.  . |. |.|||. |....| |... |.. | |...||.||..  ||..  .. . .||...
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

QTKFFAA-CIVVGLEYLHQNGILHRDIKPENLVFDNKGYLRITDLGIARIWKPENSSDTSGTPGYMAPEVMCRQ-NHGVAVDYYALGIIVYECMMGRRP
..|| ||  ||  |||||.  | .|| ||||.  |..|.. ||| | |   .  ...   ||| |.|||.  .   || .||  ||||..|| . |  |
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP
Kinase 3655.AA MAST 22-169 32 1.1e-45 137.16 In-house 1-151 (337) Show / Hide 
Range on Protein: 22-169
Range on HMM: 1-151/337
Sequence Identity: 32% (49 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLYALKEMSKSKIISKRSVQSVMNEKQLLSSLRHDFLINMIYAFSD--RSNLYLVMDLLTGGDLRFHISRHR-RFT
|.|  .|..|..|.|..|. || ....|.| . .. .| |  |..|. |.  |. .  .|  .| |.|    .  |..||. . |||  ....    .. 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EQQTKFFAACIVVGLEYLHQNGILHRDIKPENLVFDNKGYLRITDLGIARI
|  .|.  | .| .|||||  || |||.||.|...| .| . .|| | . .
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKV
Kinase 3655.AA MAST 180-256 36 5.6e-18 50.91 In-house 230-313 (337) Show / Hide 
Range on Protein: 180-256
Range on HMM: 230-313/337
Sequence Identity: 36% (31 aa)

GTPGYMAPEVMCRQN-HGVAVDYYALGIIVYECMMGRRPYLGRTRQE-IRDQILARQVQIKKSEV-----PDKWSLEAADFCNR
||| |.||||  .|  .| .||....|||.||   |  |  | |..| | ..|. ..  |   |.      |. | || | ...
GTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKK
Kinase 3655.AA TyrKc 22-261 17 1.7e-14 11.62 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-261
Range on HMM: 1-280/280
Sequence Identity: 17% (52 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLYALKEMSKSKIISKRSVQSVMNEKQLLSSL--RHDFLINMIYAFSDR-------SNLYLVMDLLTGGDLRFHIS
  .  ..|.| ||.|.| . |   .  | | . ...      ..  |.| .....|  .|. ..... . ..          |..|| .  .|||. .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RHRR-FTEQQTKFFAACIVVGLEYLHQNGILHRDIKPENLVFDNKGYLRITDLGIARIWKPE------NSSDTS----GTPG-----YMAPEVMCRQNHG
.||. .. ..   |.  |  | ||||.... |||.   |   ....  .|.| | .| .. .       .  ..    |. .      ||||..      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

VAVDYYALGIIVYE-CMMGRRPYLG-----RTRQEIRDQILARQVQIKKSE--------VPDKWSLEAADFCNR----------VRKNL
 . | .. |.  .| .  |  || |      . ||.. .. ..    .  .         ||.      . ...          ... .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 3655.AA Pkinase_Tyr 22-146 23 5.5e-11 37.83 Pfam 1-137 (270) Show / Hide 
Range on Protein: 22-146
Range on HMM: 1-137/270
Sequence Identity: 23% (32 aa)

FYFHFVIGRGGFGKVWKVESK----KQKQLYALKEMSKSKIISKRS--VQSVMNEKQLLSSL-RHDFLINMIYAFS-DRSN--LYLVMDLLTGGDLRFHI
  |  ..|.| ||.|.| . |    ..|.  | | . |    ...    .. |.| .....| .|. ..... . . ..    .|.|| .  .|||. . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

SRH----RRFTEQQTKFFAACIVVGLEYLHQNGILHRDI
 .|    ...| ..   ... |  |.|||..... |||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 3655.AA SGK 274-299 44 2.4e-09 24.51 In-house 257-283 (283) Show / Hide 
Range on Protein: 274-299
Range on HMM: 257-283/283
Sequence Identity: 44% (12 aa)

KQLIQRKPMNRLGLN-GPEEVKNHPWF
..| |. | .||| . . .|.||||.|
QGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 3655.AA MAST 274-299 53 2.6e-08 20.79 In-house 312-337 (337) Show / Hide 
Range on Protein: 274-299
Range on HMM: 312-337/337
Sequence Identity: 53% (14 aa)

KQLIQRKPMNRLGLNGPEEVKNHPWF
|.| |  |  ||| || .|.|.|| |
KKLLQPNPKKRLGANGADEIKQHPFF
Kinase 3655.AA RSK 274-299 42 1.9e-07 23.65 In-house 251-278 (278) Show / Hide 
Range on Protein: 274-299
Range on HMM: 251-278/278
Sequence Identity: 42% (12 aa)

KQLIQRKPMNRLG--LNGPEEVKNHPWF
... .| | .|||   .. ||.|.||||
RKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 3655.AA PKA 274-299 42 0.001621 12.81 In-house 236-263 (263) Show / Hide 
Range on Protein: 274-299
Range on HMM: 236-263/263
Sequence Identity: 42% (12 aa)

KQLIQRKPMNRLG--LNGPEEVKNHPWF
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KKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 3655.AA CAMK 291-299 55 0.003822 5.18 In-house 417-425 (425) Show / Hide 
Range on Protein: 291-299
Range on HMM: 417-425/425
Sequence Identity: 55% (5 aa)

EEVKNHPWF
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EQCLNHPWM
Kinase 3655.AA Pkinase 274-299 30 0.005221 11.72 Pfam 271-293 (293) Show / Hide 
Range on Protein: 274-299
Range on HMM: 271-293/293
Sequence Identity: 30% (8 aa)

KQLIQRKPMNRLGLNGPEEVKNHPWF
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KWCLCKDPKKRPT---AEQILQHPWF