Gene 20331 (Tetrahymena)

20331

Species: Tetrahymena
Alias: 53.m00233, 3712.m00093, PreTt20331, 411, 20331, TTHERM_00457010
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
20331.AA Protein None 1174 None Fasta, JSON
20331.kin_dom Protein Kinase Domain None 259 None Fasta, JSON
20331.NA RNA None 3525 None Fasta, JSON

Protein domain

Protein domains of 20331.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 20331.AA AGC 697-955 28 3.9e-139 362.15 In-house 1-395 (395) Show / Hide 
Range on Protein: 697-955
Range on HMM: 1-395/395
Sequence Identity: 28% (114 aa)

FNFHYVIGKGGFGKVWKVEHR------KTRQLFAMKEMSKSL-IITKK--SVNSVMNE------------RNLLSQLK----------HPFLVN-MFYAF
|.|. |||||.||||. |...       | ...||| ..|.  |. ||   |  .|.|            || |....          |||.|. ..|.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDREN--LHLVMDLMP---------GG-DLRYHI-G--RQRRFSEEQTRFFVAC-------IFMGLEYLHD-NNIIHRD-IKPENLVLDSSGYVRITDLG
|| ..  |..||..||         || .| .|. |  ...||.||..||. |.       | ..|||||. ..||||| .||||..||. |....|| |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

IART--------------------------------------WKPDN--------------ANDTSG--TPGYMAPEVMCRQPHTFAVDYFA--LGVLAY
 .                                        |. .|              ..   |  || |||||.     ...|.|. .  ||.| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFMLGRRPYLGRS----------RKEIRDQILAKR-VQIKKHEIP----------DGWSLEAADFINRLIERKPANRLGIN-------GPAEVKNHPWI
|.. |. |. | .          ..|. ..|.  | .. .| ..|          . .| || |.|..|... |..||| .       |  |.||||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 20331.AA Ciliate-E2-Unclassified 697-955 30 1.8e-116 393.26 In-house 1-352 (352) Show / Hide 
Range on Protein: 697-955
Range on HMM: 1-352/352
Sequence Identity: 30% (109 aa)

FNFHYVIGKGGFGKVWKVEHRKTRQLFAMKEMSKSLIITKKSVNSV---------MNERN-------------LLSQLKHPFLVNMFYAFQDRENLHLVM
......||.||||||.|..|.|. |..|||.|.|. |. .|.....         ||...             .|....|||.|.|||.|||..|. .||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

DLMPGGDLRYHIGRQ-----------------RRFSEEQTR-----FFVACIFMGLEYLHDNN-IIHRDIKPENLVLDSSG---YVRITDLGIAR-----
....||||...|  .                 ..|.|.|..     |. |.|  |||||| .| ||||||||||...|..|   |..|.|.||..     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------TWKPDNANDTSGTPGYM----APEVMCRQPHT----FAVDYFALGVLAYEFMLGRRPYLGRSRKE----------------IRDQILA
             ||........|||.||    ||||...| .     ...|...|||..||.. |..|. ......                ....|..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

KRVQIKKHE---IPDGWSLEAADFINRLIERKPANRLGIN-GPAEVKNHPWI
| .|..|..   ||..|| ||.||||.|. ... .... . .. ...||||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 20331.AA SGK 697-955 38 1.1e-98 305.34 In-house 1-283 (283) Show / Hide 
Range on Protein: 697-955
Range on HMM: 1-283/283
Sequence Identity: 38% (110 aa)

FNFHYVIGKGGFGKVWKVEHRKT------------------RQLFAMKEMSKSLII-------TKKSVNSVMNER-NLLSQLKHPFLVNMFYAFQDRENL
| |  |||||.||||  |.| ..                   ...|||  .|  ||        ||... .| || ..|. .||||.||  ||||  . |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

HLVMDLMPGGDLRYHIGRQRRFSEEQTRFFVACIFMGLEYLHDNNIIHRDIKPENLVLDSSGYVRITDLGIAR-TWKPDNANDT-SGTPGYMAPEVMCRQ
 .||| . ||.. ||. | ..|.| . || .| |   |||||. .||.|| ||||..||. |....|| | .    |. .   |  ||| |.||||.  |
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PHTFAVDYFALGVLAYEFMLGRRPYLGRSRKEIRDQILAKRVQIKKHEIPDGWSLEAADFINRLIERKPANRLGIN-GPAEVKNHPWI
||  .|| . || . ||.| |  |.  | ...  |.|. .  ||..     . | .| | |. | .. | .||| . . .|.||||. 
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPP-----QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 20331.AA Ciliate-E2 697-955 25 1.7e-98 333.49 In-house 1-365 (365) Show / Hide 
Range on Protein: 697-955
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

FNFHYVIGKGGFGKVWKVEHRKTR-----------------------QLFAMKEMSKSLIITKKSVNSVM----------NERNLLSQLKHPFLVNMFYA
..|. .||.|.||.|.|....|..                       ...||| |.|. |. .|.....|          ||.|.|.||.||....|...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DRENLHLVMDLMPGGDLRYHIG------------------RQRR-FSEEQTR-------FFVACIFMGLEYLHDNN-IIHRDIKPENLVLDSSGYV
||  |..|. |||..  ||||...|                   .... .......       |..|||  .||||| .| ||||||||||...     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RITDLGIAR---------------TWKPDNANDT-------------------SGTPGYMAPEVMCRQP---------HTFAVDYFALGVLAYEFMLGRR
 |.|.|...                |...  |||                    |||||||||.  ...         .....|...|||. ||.. |..
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYLGRSRKEIRDQILAKRVQIKKHE-------------IPDGWSLEAADFINR----LIERKPANRLGINGPAEVKNHPWI
|.         .||. . ... . |             ... ||.|. |.|..    .....| .|..  |. ...||||.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 20331.AA S_TKc 697-955 30 6e-96 325.97 SMART 1-231 (231) Show / Hide 
Range on Protein: 697-955
Range on HMM: 1-231/231
Sequence Identity: 30% (84 aa)

FNFHYVIGKGGFGKVWKVEHRKTRQLFAMKEMSKSLIITKKSVNSVMNERNLLSQLKHPFLVNMFYAFQDRENLHLVMDLMPG--GDLRYHIGRQRR---
. .. .||||.||||.|. |.|| ...|.|...          .....|...|.. .||..|.....||| ..|..||....|  |||. .| ...|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEEQTRFFVACIFMGLEYLHDNNIIHRDIKPENLVLDSSGYVRITDLGIARTWKPDNANDTSGTPGYMAPEVMCRQPHTF-AVDYFALGVLAYEFM
   |.| ..||... |. .|||.|...|||||.||||. ||.   . |.| |.||       .   ||| ||||||.   .... ..|  ..|.. ||..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

LGRRPYLGRSRKEIRDQILAKRVQIKKHEIPDGWSLEAADFINRLIERKPANRLGINGPAE----VKNHPWI
 |. |.     ... ..|.               | || |||... .. |..|...    .    .|.|||.
CGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 20331.AA Akt 697-955 40 2.8e-89 285.55 In-house 1-264 (264) Show / Hide 
Range on Protein: 697-955
Range on HMM: 1-264/264
Sequence Identity: 40% (108 aa)

FNFHYVIGKGGFGKVWKVEHRKTRQLF-AMKEMSKSLIITKKSVNSVMNERNLLSQLKHPFLVNMFYAFQDRENLHLVMDLMPGGDLRYHIGRQRRFSEE
|.| .|.||| ||||  |.  .| ... |||  .|. || |. |  .. |||.|   .|||.||. |.||. ..| .||| ..||.| ||. |.|||||.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

QTRFFVACIFMGLEYLHDNNIIHRD-IKPENLVLDSSGYVRITDLGIAR-T-WKP-DNANDTSGTPGYMAPEVMCRQPHTFAVDYFA-LGVLAYEFMLGR
..||..| |. ..|.|| .||| ||  ||||...|. |....|| | ..    |  | ..   ||| |.|||.   . || |||  . ||.. ||.| ||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

RPYLGRSRKEIRDQILAKRVQIKKHEIPDGWSLEAADFINRLIERKPANRLG--INGPAEVKNHPWI
 |.  . ...  ..|. . |....    | .| |. |.|..| .. | .|||  .|.  |.|.||| 
PPFYNQDHHQMFKKIKNQPVKFPDK---DWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 20331.AA AktR 697-955 36 9.7e-86 291.16 In-house 1-268 (268) Show / Hide 
Range on Protein: 697-955
Range on HMM: 1-268/268
Sequence Identity: 36% (99 aa)

FNFHYVIGKGGFGKVWKVEHR-KTRQLFAMKEMSKSLIITKKSVNSVMNERNLLS-QLKHPFLVNMFYAFQDRENLHLVMDLMPGGDLRYHIGRQRRFSE
| .. ..|||.||||  |... .. ...|||  .|. || ..    . .||| .  . .|||.|...|.||..|.| ..|. .|||.| .|. ....|||
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EQTRFFVACIFMGLEYLHDN-NIIHRDIKPENLVLDSSGYVRITDLGIAR--TW--KPDNANDTSGTPGYMAPEVMCR-QPHTFAVDYFALGVLAYEFML
||.||. | |  .|||||.. ||| ||.||||..||. |.|.||| | ..      . . |.   ||| |||||.  . ..|...||. |.|.. || . 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GRRPYLGRSRKEIRDQILAKR-VQIKKHEIPDGWSLEAADFIN-RLIERKPANRLG--INGPAEVKNHPWI
|  |    ..... . |. |. ....... .   | .. |.|. .|  . | .|||   ||. |.|.||| 
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYF---SSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 20331.AA RSK 700-955 35 3e-83 282.88 In-house 1-278 (278) Show / Hide 
Range on Protein: 700-955
Range on HMM: 1-278/278
Sequence Identity: 35% (101 aa)

HYVIGKGGFGKVW---KVEHRKTRQLFAMKEMSKSLIITK-KSVNSVMNERNLLSQLK-HPFLVNMFYAFQDRENLHLVMDLMPGGDLRYHIGRQRR---
. | |.||.|||    |..|..|.|..|||  .|. |... |..  .| ||| |.  . |||.|. .||||. . |.|.|....||.| .|. ....   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSEEQTRFFVACIFMGLEYLHDNNIIHRDIKPENLVLDS---SGYVRITDLGIARTWKPDNANDTS---GTPGYMAPEVMC---RQP-HTFAVDYFALGV
|||.  .|  | | . .|.||.  |||||.|||| ..|.   .| ...|| | ..  ..|. . |    .|  |||||.     .|  |. |.|.. |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LAYEFMLGRRPYLG---RSRKEIRDQILAKR--VQIKKHEIPDGWSLEAADFINRLIERKPANRLG--INGPAEVKNHPWI
| ||   |..|. |    .|||| ..|. ..  .   ......  | || |.|... .| |..|||   .. .|.|.|||.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSL---TMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 20331.AA Pkinase 697-955 27 6.5e-82 283.24 Pfam 1-293 (293) Show / Hide 
Range on Protein: 697-955
Range on HMM: 1-293/293
Sequence Identity: 27% (83 aa)

FNFHYVIGKGGFGKVWKVEHRKTRQLFAMKEMSKSLIITKKSVNSVM-NERNLLSQLKHPFLVNMFYAFQDRENLHLVMDLMPGG----DLRYHIG--RQ
. .. .||.|.||.|.|  |..|....|.|...|. .  .| .. .  .|  ..  |.||. | ....|.|. ....||....||    ||  .|   |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RRF--SEEQTRFFVACIFMGLEYLHDNNIIHRDIKPENLVLDSSGYV----RITDLGIAR---TWKPDNANDTSGTPGYMAPEVMC-RQPHTFAVDYFAL
..|  ||.. .|..  |. ||||.|...|||||.||||. .|. |..    .|.| |.|.   . .   ...  |||.||||||   .|... .|| ...
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLAYEFMLGRRPYLGR--SRKEIRDQILAKRVQIKKHEIPDGWS---------------------LEAADFINRLIERKPANRLGINGPAEVKNHPWI
|.. ||...|| |. |.  . . .... . .|.  .. . .  |.                      |. |||.......|. |..   ......|||.
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase 20331.AA CAMK 702-955 19 3.6e-77 248.04 In-house 1-425 (425) Show / Hide 
Range on Protein: 702-955
Range on HMM: 1-425/425
Sequence Identity: 19% (82 aa)

VIGKGGFGKVWKVEHRKTR------------QLFAMKEMSKSLII-------------------------TKKSVNSVMNERNLLSQ-------LKHPFL
..|.|.|||| ...|..|             | .|.| ..|. .                          . |.  .|..| .....       |.|| .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNMFYAFQD-------------------RENLHLVM---DLMPGG----DLRYHIGRQ---------------RRFSEEQTRFFVACIFMGLEYLHDNNI
.... ...|                   ......||   ....||    ||  .| ..               .||.|...|...  |  ...|.|..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENLVLDSSG----------------Y-VRITDLGIARTWKPDN-------------------------ANDTSGTPGYMA-PEVMCR------
.|||.||||. ||...                . . |.| | |.  .|..                          ..  |||.||| |||  .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------QPHTFAVDYFALGVLAYEFMLGRRPYLGRSRKEIR--------DQILAKRVQIKKHE-IPDGWSL-----------------------EAAD
        .......|  ..||. |    |. |. | ...||.        |. | ....  | . .|. .|                        |. |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FINRLIERKPANRLGINGPAEVKNHPWI
.|... .. | .|. |   ....||||.
LIRKMLQVDPEKRMTI---EQCLNHPWM
Kinase 20331.AA MAST 697-838 39 1.5e-57 174.07 In-house 154-298 (337) Show / Hide 
Range on Protein: 697-838
Range on HMM: 154-298/337
Sequence Identity: 39% (57 aa)

FNFHYVIGKGGFGKVWKVEHRKTRQLFAMKEMSKSLIITKKSVNSVMNERNLLSQLKHPFLVNMFYAFQD--RENLHLVMDLMPGGDLRYHIGRQR-RFS
|.|  .|.||..|.|..|.|.||...|||| . .. .| |. |..|. ||| |.... || |.|||.||   .. | .||. | |||   ..     .. 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EEQTRFFVACIFMGLEYLHDNNIIHRDIKPENLVLDSSGYVRITD
|. ... .| .  .|||||   |.|||.||.|...|| | . .||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTD
Kinase 20331.AA MAST 697-838 42 3.1e-55 176.34 In-house 155-296 (334) Show / Hide 
Range on Protein: 697-838
Range on HMM: 155-296/334
Sequence Identity: 42% (61 aa)

FNFHYVIGKGGFGKVWKVEHRKTRQLFAMKEMSKSLIITKKSVNSVMNERNLLSQLKHPFLVNMFYAFQDRENLHLVMDLMPGGDLRYHIGRQRRFSEEQ
|.|  .|.||..|||..|.|.||...|||| . ||  | |. |..|. ||| |.... || |.|||.|| ...| .||. | |||.  ..    .| |. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

TRFFVACIFMGLEYLHDNNIIHRDIKPENLVLDSSGYVRITD
... .| . ..|||||   |.|||.||.|...||.| . .||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTD
Kinase 20331.AA MAST 855-955 37 2.6e-26 81.53 In-house 226-334 (334) Show / Hide 
Range on Protein: 855-955
Range on HMM: 226-334/334
Sequence Identity: 37% (42 aa)

GTPGYMAPEVMCRQP-HTFAVDYFALGVLAYEFMLGRRPYLGRSRKEIRDQILAKRVQIKK-HEIPDG--------WSLEAADFINRLIERKPANRLGIN
|||.|.||||  .|. |  .||....|.  |||. |  |  . .. || ..|| ..       |.|.|         | || | |..| .  |  ||| |
GTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNC---NEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGAN

-GPAEVKNHPWI
 | .|||.|| .
NGADEVKQHPFF
Kinase 20331.AA MAST 855-955 36 5.2e-26 75.89 In-house 230-337 (337) Show / Hide 
Range on Protein: 855-955
Range on HMM: 230-337/337
Sequence Identity: 36% (40 aa)

GTPGYMAPEVMCRQP-HTFAVDYFALGVLAYEFMLGRRPYLGRSRKE-IRDQILAKRVQIKKHEIPDG--------WSLEAADFINRLIERKPANRLGIN
||| |.||||  .|. .  .||....|.  |||  |  |  | .. | | ..|. .   |   | |..         | || | |..| .  |  ||| |
GTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREI---EWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGAN

GPAEVKNHPWI
| .|.|.||  
GADEIKQHPFF
Kinase 20331.AA TyrKc 697-933 22 4.1e-16 37.88 SMART 1-280 (280) Show / Hide 
Range on Protein: 697-933
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

FNFHYVIGKGGFGKVWKVEHRKTRQLFAMKEMSKSLIITKKSVNSVMNERNLLSQL--KHPFLVNMFYAFQDR-------ENLHLVMDLMPGGDLRYHIG
  .  ..| | ||.|.| . .   .  | | . ..       .   |.| .....|  .|| .|... .  .        | | .|| .||.|||. .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RQRR-FSEEQTRFFVACIFMGLEYLHDNNIIHRDIKPENLVLDSSGYVRITDLGIARTWKPD-------NANDTS---GTPG-----YMAPEVMCRQPHT
. |. .. ..   |   |  | ||||..|.||||.   |  ... . |.|.| | .| .. |          ...   |. .      ||||..     |
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

FAVDYFALGVLAYE-FMLGRRPYLG-----RSRKEIRDQILAKRVQIKKHE--------IPDG--------WSLEAAD-----FINRLI
.. | .. ||. .| | .|  || |      | .|.. .. . .   . ..         ||         |  ...|      | ...
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 20331.AA Pkinase_Tyr 697-844 26 4.7e-15 51.62 Pfam 1-160 (270) Show / Hide 
Range on Protein: 697-844
Range on HMM: 1-160/270
Sequence Identity: 26% (43 aa)

FNFHYVIGKGGFGKVWKVEHR----KTRQLFAMKEMSKSLIITKKS--VNSVMNERNLLSQL-KHPFLVNMFYAFQ-DREN--LHLVMDLMPGGDLRYHI
  |  ..|.| ||.|.| . .    .|..  | | . |    ...     . |.| ....|| .|| .|..  .   ..|   . .|| .||.|||. . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

GR----QRRFSEEQTRFFVACIFMGLEYLHDNNIIHRDIKPENLVLDSSGYVRITDLGIART
 .    ..... ..   . . | .|.|||...|.||||.   |  ..... |.|.| | ||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD