Gene 30298 (Tetrahymena)

30298

Species: Tetrahymena
Alias: 3705.m00136, PreTt30298, 471, 33.m00310, TTHERM_00329930, 30298
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: TKL
Family: TKL-ciliate5

Sequence

Name Sequence Type Origin Length Description Download
30298.AA Protein None 675 None Fasta, JSON
30298.kin_dom Protein Kinase Domain None 165 None Fasta, JSON
30298.NA RNA None 2028 None Fasta, JSON

Protein domain

Protein domains of 30298.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 30298.AA TKL-Unique 577-650 31 7.1e-23 77.61 In-house 209-290 (290) Show / Hide 
Range on Protein: 577-650
Range on HMM: 209-290/290
Sequence Identity: 31% (26 aa)

SDTYSFAFILYELFVGRE------PFQNVSLKELKEIVVE--KESRPKIPSEIPEEIQKLIRCCWYQRAQDRPDFESICEHL
|| |||...|.|.. .        |.|... ....|.| .  ...||.||...|.|...||. || .  ..|| |..| . |
SDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 30298.AA TKL 574-650 23 6.3e-22 75.75 In-house 267-364 (364) Show / Hide 
Range on Protein: 574-650
Range on HMM: 267-364/364
Sequence Identity: 23% (23 aa)

DPASDTYSFAFILYELFVGREPFQNVSLKELK---------EIVVEKESRPKIP------------SEIPEEIQKLIRCCWYQRAQDRPDFESICEHL
....| |||. .|.|.. ...|...    . .         ..|..|  || ||            . .|... ||. .|| . ...|| |. | ..|
SEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 30298.AA Dicty4-Unclassified 576-650 38 6.2e-21 68.39 In-house 188-263 (263) Show / Hide 
Range on Protein: 576-650
Range on HMM: 188-263/263
Sequence Identity: 38% (29 aa)

ASDTYSFAFILYELFVGREPFQNVS-LKELKEIVVEKESRPKIPSEIPEEIQKLIRCCWYQRAQDRPDFESICEHL
.|| ||.| .||||  | ||.| .    ..   | .|  |||||. ..  ..|||  ||    . || .. | . |
KSDVYSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 30298.AA MLK 571-650 28 6.3e-21 69.42 In-house 211-291 (291) Show / Hide 
Range on Protein: 571-650
Range on HMM: 211-291/291
Sequence Identity: 28% (23 aa)

STNDPASDTYSFAFILYELFVGREPFQ-NVS-LKELKEIVVEKESRPKIPSEIPEEIQKLIRCCWYQRAQDRPDFESICEHL
.... ..| .|.. .|.|.. ...|..  .. .  . ....... || |||..|| . ||. .|| | . .||.| .| .||
EKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGL-RPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 30298.AA RIPK 574-650 25 5.2e-19 61.4 In-house 206-290 (290) Show / Hide 
Range on Protein: 574-650
Range on HMM: 206-290/290
Sequence Identity: 25% (22 aa)

DPASDTYSFAFILYELFVGREPFQNVSLKELKEIVVEKESRPK---IPSEIPEE-----IQKLIRCCWYQRAQDRPDFESICEHL
.|..| ||||....|.. ...|. .. . . ....... .||.   .| . ||      . .|.. || | ..||| |  . |  
TPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase 30298.AA Dicty5 578-654 38 5.3e-16 51.55 In-house 185-260 (260) Show / Hide 
Range on Protein: 578-654
Range on HMM: 185-260/260
Sequence Identity: 38% (30 aa)

DTYSFAFILYELFVGREPFQNVSLKELKEIVVEKESRPKIPSEIPEEIQKLIRCCWYQRAQDRPDFESICEHLENYS
| |||. .|.|.|   ||. |.   .   . | |  || ||  .| || .||  || |. . || |  ||. .|  .
DVYSFGIVLWEMFTRKEPYDNINNWNI-PVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 30298.AA LRRK 577-652 30 5.6e-16 52.99 In-house 263-351 (351) Show / Hide 
Range on Protein: 577-652
Range on HMM: 263-351/351
Sequence Identity: 30% (27 aa)

SDTYSFAFILYELFVGR-EPFQNVS------LKELKEIVVEKESRPKIPSE-IPE-----EIQKLIRCCWYQRAQDRPDFESICEHLEN
.|.|||. ||.||  ..  ||.. .      . |. |  . .  ||.||..  |.     . |.||  || .  ..|| |..| . |. 
VDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 30298.AA Fer 575-651 25 2.2e-15 48.93 In-house 197-283 (283) Show / Hide 
Range on Protein: 575-651
Range on HMM: 197-283/283
Sequence Identity: 25% (22 aa)

PASDTYSFAFILYELFV-GREPFQN----VSLKEL----KEIVVEKESRPKIPSEIPEEIQKLIR-CCWYQRAQDRPDFESICEHLE
|..| .||   ..| |  | ||. .    . ....    .. ...|. ....|.. |.|| ...  .|| .   ||| . .||. |.
PKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase 30298.AA RGC 575-652 23 1.9e-14 47.33 In-house 197-300 (300) Show / Hide 
Range on Protein: 575-652
Range on HMM: 197-300/300
Sequence Identity: 23% (24 aa)

PASDTYSFAFILYELFVGREPF---QNVSLK-----ELKEIVVE-------KE---SRPKIPSE-------IPEEIQKLIRCCWYQRAQDRPD-FESICE
.. | |||. |.||... ..|.    .. ..     ...||. |        .    ||.|. .       ..... .|.| ||  .  .||| |..|..
QKGDVYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRK

HLEN
.|..
QLKT
Kinase 30298.AA RGC 575-652 23 2.3e-14 47.33 In-house 197-300 (300) Show / Hide 
Range on Protein: 575-652
Range on HMM: 197-300/300
Sequence Identity: 23% (24 aa)

PASDTYSFAFILYELFVGREPF---QNVSLK-----ELKEIVVE-------KE---SRPKIPSE-------IPEEIQKLIRCCWYQRAQDRPD-FESICE
.. | |||. |.||... ..|.    .. ..     ...||. |        .    ||.|. .       ..... .|.| ||  .  .||| |..|..
QKGDVYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRK

HLEN
.|..
QLKT
Kinase 30298.AA Pkinase 574-650 20 4e-12 43.94 Pfam 190-293 (293) Show / Hide 
Range on Protein: 574-650
Range on HMM: 190-293/293
Sequence Identity: 20% (21 aa)

DPASDTYSFAFILYELFVGREPFQNV----SLKELKEIVVEKESRPKIPSEI----------------------PEEIQKLIRCCWYQRAQDRPDFESIC
.|..| .|.  ||||.. || ||..     .  . ....... ..|   ..                       .|| ...|..|. .  ..|| .| |.
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

EH--L
.|  .
QHPWF
Kinase 30298.AA Pkinase_Tyr 576-650 35 4.9e-12 41.39 Pfam 194-270 (270) Show / Hide 
Range on Protein: 576-650
Range on HMM: 194-270/270
Sequence Identity: 35% (27 aa)

ASDTYSFAFILYELFV-GREP-FQNVSLKELKEIVVEKESRPKIPSEIPEEIQKLIRCCWYQRAQDRPDFESICEHL
.|| .||   ..|.|  |..| ....|  |..| . |.  | ..|   |.|| .|.. || . ..||| |. | |.|
KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc 30298.AA TyrKc 358-650 14 2.9e-09 -72.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 358-650
Range on HMM: 1-280/280
Sequence Identity: 14% (49 aa)

LQENEK---GHHG---LGKIFHSCDNKAIRKIEVKQLSQYIIDEIKSDVYQQ----KQF--PAKKLVRVLEYQCLA-------DQLLLAYPFYNNRSLRY
.. ..|   |. |   .|.          ..  || |  .     . | ..     ...    . .|| . .           ..|..   .  . .|. 
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

IIQKQSVGILNIQSQCNKETFTSSQTNETSQFTLASKVNLALKIAYLIRDMHHQGFIHGHLHSDNILLSSKLYPRIAGTFLILPNISPLNQIFKQIDLGL
 ..|                           .... ... .. ||   .  |....||  |   |.|.....                      ..  . 
YLRKHRPK-----------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----------------------TVKISD

NALKKYLGLK-------GQYSN----KSQF------TSPENLLARGPVVSTN--DPASDTYSFAFILYELF-VGREPFQN-----VSLKELKEIVVEKES
  | .... .         |.      . .      ..|| .        ..   ..|| .||   ..|.|  | .|  .     .| .|. | | . . 
FGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYR

RPKIPS-------EIPEEIQKLIRCCWYQRAQDRPDFESICEHL
.|. |.       . |.|. .....||   . ||| |. |.| .
MPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
S_TKc 30298.AA S_TKc 347-650 15 8.9e-07 -77.5 SMART 1-231 (231) Show / Hide 
Range on Protein: 347-650
Range on HMM: 1-231/231
Sequence Identity: 15% (52 aa)

FEL-----AGDISKVKLQENEKGHHGLGKIFHSCDNKAIRKIEVKQLSQYIIDEIKSDVYQQKQFPAKKLVRVLEYQCLADQLLLAYPFYNN--RSLRYI
.|.      |  .||..  . |          .    || .|      . |. ||.  . ..     . .|. ...    | | .   . ..   .|. .
YEILRKIGKGAFGKVYKCRHKK----------TGRIVAIKIIK-----EHIRREIQ--ILKK---HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDY

IQKQSVGILNIQSQCNKETFTSSQTNETSQFTLASKVNLALKIAYLIRDMHHQGFIHGHLHSDNILLSSKLYPRIAGTFLILPNISPLNQIFKQIDLGLN
|.|.  . |.                  ..|.      ..  |.  .  .| .|.||  |  .||||..                       | .| || 
IKKRGRHGLR------------------FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------------HIKICDFGLA

ALKKYLGLKGQYSNKSQ-----FTSPENLLARGPVVSTNDP-ASDTYSFAFILYELFVGREPFQNVSLKELKEIVVEKESRPKIPSEIPEEIQKLIRCCW
..            ...     . .|| |          .. ..| .|.  ||||...|. ||.   .... ....            ..|   .|| |.
RQL-----------TTFCGTPWYMAPEVL--------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCL

YQRAQDRPDFESICE-------H--L
    ..||    . .       |  .
QKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 30298.AA TKL 423-510 16 0.257217 0.51 In-house 112-177 (364) Show / Hide 
Range on Protein: 423-510
Range on HMM: 112-177/364
Sequence Identity: 16% (16 aa)

QLLLAYPFYNNRSLRYIIQKQSVGILNIQSQCNKETFTSSQTNETSQFTLASKVNLALKIAYLIRDMHHQG--------FIHGHLHSDNILLSSKL
|| . . .. . ||.....                              .  ....|| ||  .  .| ..         ||  | |.|||. ...
QLCIVMEYCPGGSLLHYLH------------------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENW