Gene 9438 (Tetrahymena)
9438
Group:
Other
Family:
Ciliate-B1
Sequence
Protein domains of 9438.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
Kinase | 9438.AA | Ciliate-B1 | 11-276 | 47 | 2.5e-164 | 552.2 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 11-276 Range on HMM: 1-290/290 Sequence Identity: 47% (137 aa) ILKNKILGQGGFSQVFQGKICQDDEARNFVAIKKVSKTTLDG--QENKNYEKELEISQKIFEIERN-------DPCQYIMNIIDFCQLDESYYIITEYYE ...|...|||..||||.|..||.......||.||..|.|.|. |.||.|..||||.|.......| .||..|.||.|..|....||||.||.| YQQNNVIGQGAISQVFYGQFCQNQQCQQEVAVKKITKQTQDNDKQQNKYYQQELEIIQCLIKKMNNNKISCQSSPCDHICNIYDVIQCQQQYYIIMEYCE SGDFLTFLNQNFEYFTLDIVLDILIQIVKAINYLHKHNITHRDLKPENILIS---------KQQNMYFVKVADFG--SATVS-DFSSLSGTPNYMAPEIF .||...........||.|||||..|||.|.|.|||||.|.|||||||||||. ||||.|..|..||| ..... ...|..||.|||||||. QGDLYNYIYNCHQNFTHDIVLDFCIQIAKGIQYLHKHKICHRDLKPENILIHKKNVPIYYNKQQNHYIFKITDFGISKMQQEYMMQSCVGTINYMAPEIL Y-NKILTNSIDIWSFGCLAYEILTKQQFFC--GKNAQQVVRQIIQYDECLYKNQNQNDQYFQIHQLIQKYCLQPDPEKRQTAQFIIDELS . |.......|||||||..|||.|..|.|| |...|.|..||.....|.|....||..|..|.|||||||||||||.|.|...|||.|. NFNQQYDKKVDIWSFGCIMYEIITNEQLFCSLGNTQQEVANQIRNFQCCDYQCHFQNNIYQEIQQLIQKYCLQPDPENRITIDQIIDRLM |
|||||||||
Kinase | 9438.AA | S_TKc | 11-278 | 26 | 1.1e-53 | 185.61 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 11-278 Range on HMM: 1-231/231 Sequence Identity: 26% (74 aa) ILKNKILGQGGFSQVFQGKICQDDEARNFVAIKKVSKTTLDGQENKNYEKELEISQKIFEIERNDPCQYIMNIIDFCQLDESYYIITEYYES--GDFLTF . ...|.|.|..|.... ||||... .. ..|..| .| . .| ...|..| ...|...|| . || ... YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK---------EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDY LNQNFE-----YFTLDIVLDILIQIVKAINYLHKHNITHRDLKPENILISKQQNMYFVKVADFGSATVSDFSSLSGTPNYMAPEIFYNKILTNSIDIWSF . .. .|. . .. ||..|..|.|.|.| ||||||||||... .|..|||.|.. ... |||.|||||.. . . ..|.||. IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--TTFCGTPWYMAPEVL--GYGKCKCDWWSC GCLAYEILTKQQFFCGKNAQQVVRQIIQYDECLYKNQNQNDQYFQIHQLIQKYCLQPDPEKRQTAQFIID-E-----LSQL ||. || |. . |. . |.. ..| . ..|.| ||| ||||| || . | . GCILYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRK-CLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
Kinase | 9438.AA | Pkinase | 11-233 | 25 | 1.4e-51 | 182.44 | Pfam | 1-234 (293) | Show / Hide |
Range on Protein: 11-233 Range on HMM: 1-234/293 Sequence Identity: 25% (64 aa) ILKNKILGQGGFSQVFQGKICQDDEARNFVAIKKVSKTTLDGQENKNYEK--ELEISQKIFEIERNDPCQYIMNIIDFCQLDESYYIITEYYESG----D . . ...|.|.|..| ..|.. . ||.|...| . . ..... . |..| ... . .| ..|... . ..|...|| | | | YHIGRKIGSGSFGCV---YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-N------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMD FLTFLN--QNFEY-FTLDIVLDILIQIVKAINYLHKHNITHRDLKPENILIS-KQQNMYFVKVADFGSATV-----SDFSSLSGTPNYMAPEIFYNKIL- ... .. . |. . . ... ||.....|.|...| |||||||||||. . .. .||..|||.| . | .... |||.|||||. |. LFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEV----IRG ----TNSIDIWSFGCLAYEILTKQQFFCGK------NAQQVVRQIIQYD . ..|.||.||. || |... |.|. . .|....| . . GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPP |
|||||||||
Kinase | 9438.AA | AGC | 11-265 | 20 | 1.3e-50 | 127.92 | In-house | 1-373 (395) | Show / Hide |
Range on Protein: 11-265 Range on HMM: 1-373/395 Sequence Identity: 20% (78 aa) ILKNKILGQGGFSQVFQGKICQDD---EARNFVAIKKVSKTT---LDG--QENKN-----------YEKELEISQKIFE-----IERNDPCQYIMN-IID |..|.|.|..|.. . .. . |.|...| . .. .. .. .| .| .|. | . ...| . FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPI-KS-HHPFIVKILHY FCQLDES--YYIITEYYE--------SGD-FLTFLNQ---NFEYFTLDIVLDILIQ-------IVKAINYLHK-HNITHRD-LKPENILISKQQNMYFVK | .. |.. ||.. |. | . .| . .|. . . .. . || |. |||. ..| ||| |||||||. .. .| SFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED---GHIK VADFGSATVSD-------------------------------------------------------FSSLSG--TPNYMAPEIFYNKILTNSIDIWS--F .|||.... ... | ||.||||||. . . |.|| . LTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGL GCLAYEILTKQQFFCGKNAQ----------QVVRQIIQ-----YDECLYKN----QNQNDQYF--QIHQLIQKYCLQPDPEKR ||| || || . |.|.| | .. .|. .. . . | . |..| . ||.| .|..||||| GCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKK-LLCKDPEKR |
|||||||||
Kinase | 9438.AA | Ciliate-E2 | 11-269 | 22 | 3.5e-49 | 166.97 | In-house | 1-357 (365) | Show / Hide |
Range on Protein: 11-269 Range on HMM: 1-357/365 Sequence Identity: 22% (84 aa) ILKNKILGQGGFSQVFQGKICQDDEARNFVAIKKVSKTTL------DGQENKNYEKELEISQKIFEIER-NDPCQ---------------------YIMN . ..|..|||.|..|. |.... .. .|||. . . ... .| |... . ..|..|.. .. .. .|.. YKFIKKIGQGNFGSVY---KCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIK IIDFCQ--LDESYYIITEYYESGDFLTFLN-----QNFE-----YFTLDIVLDILIQIVK---------------AINYLHKHN-ITHRDLKPENILISK .... | |...|...||.. || . ... .|.| |||. ...| ||.. |..|||. | | |||.||||||. MYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-- QQNMYFVKVADFGSATVSD------------------------------------FSSLSGTPNYMAPEIFYNKI---------LTNSIDIWSFGCLAYE .|..||| .. | | .. |||.||||||. .| . ..||||.|.. || ------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE ILTKQQFFCGKNAQQVVRQIIQYDECLYKNQNQNDQYFQ-------IH--------QLIQK---YCLQPDPEKRQT-AQ |... | |.|. .. . ... .. .| .. .||.| .|| ||||| | .. MLFGKPPF---------QQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWE |
|||||||||
Kinase | 9438.AA | ULK | 11-265 | 25 | 9.1e-49 | 168.34 | In-house | 1-317 (329) | Show / Hide |
Range on Protein: 11-265 Range on HMM: 1-317/329 Sequence Identity: 25% (82 aa) ILKNKILGQGGFSQVFQG--KICQDDEARN-FVAIKKVSKTTLDGQENKNY--------EKELEISQKIFEIERNDP------CQYIMNIIDFCQLDES- . .|..||.| | .|..| |. . | | ||.|...| ... ..| .. ..| .| .|. ..| ...| .|... . . YCLNHCLGKGSFGKVYKGRNKKTK-D-YVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKL-----KSPNRHKNHHPNIVKLYDWFETSNHN -YYIITEYYESGDFLTFLNQNFE---------YFTLDIVLDILIQIVKAINYLHKHNITHRDLKPENILISKQQNM---------YFVKVADFGSATVSD .|||.|| . ||. .....| . ... .... ...||. . .|||||| |||.||.||||.. | . .|.|||| | . | NIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVD --------FSSLS------GTPNYMAPEIFY----NKILTNS-IDIWSFGCLAYEILTKQQFFCGKNAQQVV-----RQIIQYDECL--YKNQNQNDQ-- . . . ||| ||||.|. .| ... ||||.||. ||.|. . |.. ... . . | ..... |.|. . . NDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKD ------YFQIHQLIQKYCLQPDPEKR ....||.. .|| |...| GNDPQISPECKDLIRR-MLQYDEKDR |
|||||||||
Kinase | 9438.AA | TKL | 17-275 | 19 | 6.8e-47 | 162.11 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 17-275 Range on HMM: 1-364/364 Sequence Identity: 19% (71 aa) LGQGGFSQVFQGKICQDDEAR------NFVAIKKVSKTTLDGQENKNYE------------KELEISQKIFEIERNDP------CQYIMNIIDFCQLDES .|.|||..|..|| . .. . . ||.|| ... | . .. | .. |.|. |..|. .. | .. .|. .. IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC -------------YYIITEYYESGDFLTFLNQNFEYFTLDIVLDILIQIVKAINYLHKHN--------ITHRDLKPENILISKQQN-----------MYF ..|..||.. |. | .|. .. ... ..| ...|||| .| | |||||..|||. . . .. GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC VKVADFGSATVSD------------------------FSSLSGTPNYMAPEIFYNK----------------ILTNSIDIWSFGCLAYEILTKQQFF-CG .|..||| ... . .. |||..||||.. .. . ..|..||| . .|||| .. . . CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY KNAQQVVR---QIIQYDECLYKNQNQND------------QYF--QIHQLIQKYCLQPDPEKRQTAQFIIDEL .. ..... ..... |. ... . .. .. .|.|. | ..||||| ..| |...| PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQD-CWDHDPEKRPSFQEILKRL |
|||||||||
Kinase | 9438.AA | ULK | 11-265 | 24 | 4.9e-46 | 159.27 | In-house | 1-312 (324) | Show / Hide |
Range on Protein: 11-265 Range on HMM: 1-312/324 Sequence Identity: 24% (79 aa) ILKNKILGQGGFS-QVFQGKICQDDEA-RNFVAIKKVSKTTLDGQENK--------NYEKELEISQKIFEIERNDPCQY--IMNIIDFCQLDES--YYII . .|..||.| | .|..| ...... .||.|...| . ..|. . ..| .| .|. |. ... | .|... . . .||| YCLNHCLGKGSFGVKVYKG-RNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELK----HPNHHIVKLYDWFETSNHNNIYII TEYYESGDFLTFLNQNFE--------YFTLDIVLDILIQIVKAINYLHKHNITHRDLKPENILISK----------QQNMYFVKVADFGSATVSDFS--- .|| . ||. .....| . ... .... ...||. . .|||||| |||.||.||||.. .. . .|.|||| | . | MEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNNNME -SLS----------GTPNYMAPEIFY----NKILTNS-IDIWSFGCLAYEILTKQQFFCGKNAQQVV----RQIIQ---YDECLYKNQNQNDQ------- . ||| ||||.|. .| ... ||||.||. ||.|. . | . ... . . | . . . . |||. . . QQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQ-QIYIKNQPIQFPKPPKDPK -YFQIHQLIQKYCLQPDPEKR ....||.. .|| |...| ISPECKDLIRR-MLQYDEKDR |
|||||||||
Kinase | 9438.AA | Ciliate-E2-Unclassified | 11-269 | 23 | 7.6e-45 | 153.48 | In-house | 1-344 (352) | Show / Hide |
Range on Protein: 11-269 Range on HMM: 1-344/352 Sequence Identity: 23% (81 aa) ILKNKILGQGGFSQVFQGKICQDDEA----RNFVAIKKVSKTTLDGQENKNYE-KELEISQKIFEIE----------RNDPCQYIMNIIDFCQLDESYYI ..|..|||||..|.. . ..... . ..... .| . . ... | ||... .| . . .| |. .|.. .. | .. || YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI ITEYYESGDFLTFLNQNFE----------------YFTLDIVL-----DILIQIVKAINYLHKHN-ITHRDLKPENILISKQQNMYFVKVADFGSATVSD ..|| | || . ..... || .. ... ||.....|||. | | |||.||||||...... | .|..|||.. .. VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ --------------------FSSLSGTPNYM----APEIFYNKILTNS----IDIWSFGCLAYEILTKQQFFCGKNAQQ---VVRQIIQ--YDECLYKNQ ... .|||||| |||.. .. .| .||||.|...||.|. . | ..| | . |.|. |.. ||.|. QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI NQNDQYFQ---------IHQLIQK--------YCLQPDPEKRQTAQ .|....|. . . .| .|. .|.|| |.. KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFE |
|||||||||
Kinase | 9438.AA | CAMK | 16-212 | 20 | 2.9e-43 | 136.8 | In-house | 1-329 (425) | Show / Hide |
Range on Protein: 16-212 Range on HMM: 1-329/425 Sequence Identity: 20% (67 aa) ILGQGGFSQVFQGKICQDD-EAR--------NFVAIKKVSKTTLD--------------------------GQENKNYEKELEISQKIFEIERNDPCQYI .||.|.|..|. .. .. . | |||| ..|. |. .. || ..|.|| .|. .|... | TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI MNIIDFCQL-------------------DESYYIIT---EYYESG----DFLTFLNQNFE--------------YFTLDIVLDILIQIVKAINYLHKHNI ..... . |. .|... || . | | . .. .. .|| . . . ||. |..|.|.||| IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI THRDLKPENILISKQQ--NM------------YFVKVADFGSATVSD----------------------------FSSLSGTPNYMA-PEIFYNKI---- ||||||||||... . . .|..||| |.. | .. ||| ||| ||.. | VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM ----------LTNSIDIWSFGCLAYEILT . ..|.|| |.. | |. QNATDEEKPYYGPKCDMWSCGVILYIMLC |
|||||||||
Kinase | 9438.AA | STE | 12-212 | 21 | 2.8e-42 | 146.79 | In-house | 1-263 (359) | Show / Hide |
Range on Protein: 12-212 Range on HMM: 1-263/359 Sequence Identity: 21% (60 aa) LKN-KILGQGGFSQVFQGKIC------QDDEA------RNFVAIKKVS---KTTLDGQ-------ENKNYEKELEISQKIFEIERNDP-CQYIMNIIDFC ... ...|.|.| .|.... . .| ...|||... ... | . |||| |.. .| . | . .. ...| . .. . WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY QLD-------ESYYIITEYYESGDFLTFLNQNFEYFT-------------LDIVLDILIQIVKA-INYLHKHNITHRDLKPENILISKQQNMYFVKVADF . .. .|. || . | . ....... . ... |. ||.|. .|||.|.| |||.|| |||. || .|| FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDF GSAT-VSD-------------------FS-SLSGTPNYMAPEIFYN------KILTNSIDIWSFGCLAYEILT | .. ..| . .. ||| .||||. . | . . ||||.||.. | .| GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMAT |
|||||||||
Kinase | 9438.AA | CMGC | 11-229 | 16 | 6.2e-38 | 121.58 | In-house | 1-367 (513) | Show / Hide |
Range on Protein: 11-229 Range on HMM: 1-367/513 Sequence Identity: 16% (62 aa) ILKNKILGQGGFSQVFQGKICQDD-----------EARNFVAIKKVSKTTLDGQENK----------NYEKELEISQKI----------FEIERNDPCQY . | .|.| ...|.... . . | ..|||||... . . | |..| ... . . ... YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRD-DPDNKHHN -IMNIIDFCQLDE-----------------SYYIITEYYESGDFLTFLNQNF---------------------------EYFTLDIVLDILIQIVKAIN- | ...|... .. . |...|| . | . .. .| ||.. . . || .... NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKL -YLHKHN--ITHRDLKPENILISKQQNM-----------------YFVKVADFGSAT-VSD-------------------------FSSLSGTPNYMAPE |.|.|. | |||||||||||... . .|..|||.|. ... ... | | ||| KYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPE IFYN----------KILTNSIDIWSFGCLAYEILTK--------QQFFCGKNA------------QQVVRQI | . . | .||.||.|| .|..|. . .| |.. | . . ILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIF |
|||||||||
Kinase | 9438.AA | TyrKc | 11-275 | 23 | 1e-16 | 47.55 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 11-275 Range on HMM: 1-280/280 Sequence Identity: 23% (71 aa) ILKNKILGQGGFSQVFQGKICQDDEARNFVAIKKVSKTTLDGQENKNYEKELEISQKI--FEIERNDPCQYIMNIIDFCQLD-------ESYYIITEYYE | ..|.|| | | .|..|. ||.|.. . . . .|..| |. . | ... | . | ..|..|| . ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGH-------HPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMP SGDFLTFLNQNFEYFTLDIVLDILIQIVKAINYLHKHNITHRDLKPENILISKQQNMYFVKVADFG-SATVSDF-------SSLS-----GTP-----NY || . .| . . .... |.. .|| . .|||..|. |||| |.|..... ||..||| | . | . . |. HGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW MAPEIFYNKILTNSIDIWSFGCLAYEILTK-QQFFCG-----KNAQQVVRQIIQYDECLYKNQ--------NQNDQYFQIHQLIQKYCLQPDPEKRQTAQ |||| . .. | |.|||| . .||.| || | ...|.|.... | . . ..|.... | . |||.| | . MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDE----MYQIMKQ-CWHEDPEDRPTFS FIIDEL |.... EIHECF |
|||||||||
Kinase | 9438.AA | Pkinase_Tyr | 87-167 | 34 | 2.7e-13 | 45.67 | Pfam | 73-156 (270) | Show / Hide |
Range on Protein: 87-167 Range on HMM: 73-156/270 Sequence Identity: 34% (30 aa) CQ-LDES--YYIITEYYESGDFLTFLNQN---FEYFTLDIVLDILIQIVKAINYLHKHNITHRDLKPENILISKQQNMYFVKVADFG | .|. .||..|| . || |..| .. . .|. |.. .|| |. .||. .|. |||| |.|... |. .||..||| CTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NN-VVKICDFG |
|||||||||
Kinase | 9438.AA | Pkinase_Tyr | 11-49 | 30 | 0.129531 | 6.09 | Pfam | 1-40 (270) | Show / Hide |
Range on Protein: 11-49 Range on HMM: 1-40/270 Sequence Identity: 30% (12 aa) ILKNKILGQGGFSQVFQGKIC-QDDEARNFVAIKKVSKTT | ..| ||.| | .|..|. ..|. . ||.|.. .. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGA |
|||||||||
Kinase | 9438.AA | STE | 257-269 | 69 | 0.327719 | 0.18 | In-house | 337-349 (359) | Show / Hide |
Range on Protein: 257-269 Range on HMM: 337-349/359 Sequence Identity: 69% (9 aa) CLQPDPEKRQTAQ ||| ||.|| ||. CLQKDPNKRPTAS |
|||||||||
Kinase | 9438.AA | Pkinase_Tyr | 184-212 | 60 | 0.685124 | 3.64 | Pfam | 181-209 (270) | Show / Hide |
Range on Protein: 184-212 Range on HMM: 181-209/270 Sequence Identity: 60% (18 aa) MAPE-IFYNKILTNSIDIWSFGCLAYEILT |||| |.|.| | | |.|||| | .||.| MAPECINYGKFTTKS-DVWSFGVLMWEIFT |