Gene 3210 (Tetrahymena)

3210

Species: Tetrahymena
Alias: 69.m00252, 3718.m00113, PreTt03210, TTHERM_00537240, 3210, 377
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK7

Sequence

Name Sequence Type Origin Length Description Download
3210.AA Protein None 1119 None Fasta, JSON
3210.kin_dom Protein Kinase Domain None 298 None Fasta, JSON
3210.NA RNA None 3360 None Fasta, JSON

Protein domain

Protein domains of 3210.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 3210.AA ERK7 13-310 71 3.8e-213 714.38 In-house 1-292 (292) Show / Hide 
Range on Protein: 13-310
Range on HMM: 1-292/292
Sequence Identity: 71% (215 aa)

YEILSKLGRGAYGIVWKVYDKRTKQVLALKKIFDAFQNSTDAQRTFREIMFLQELD-HENIIKVINVIRAKNDRDIYVVFEYMDTDLHAVIR-VNILEDI
|||...||.||||||||.||||||||.|||||||||.|.|||||||||||||||.. |.|||..||||||.||||||.|||.|.|||||||| .|||.||
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRKGNILKDI

HKQYIMYQIFRAIKYIHSGELIHRDLKASNILVNSDCMVKVADFGLVRSIANQE--NGSTPILTEYIATRWYRAPEILLGIIELSQCSHTYTKGVDMWSI
||||||||..|||||.|||..||||||.||||..|.|||||.||||.||||.||  . ..|.||||.|||||||||||||       ||.||||||||||
HKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLG-------SHRYTKGVDMWSI

GCILGQLLLGKPIFAGTSTLNQLELILQVTGKPTYEDIEAIQSDLAITMLEAVQNNPTQNTKTLQQMIPMASDDALDLLQNLLQFNPKKRITAEQALSHP
|||||..| |||.|.||||.||.|.||....|||.||||||.|..|..|||...   .|..|||.||.|...|||.|||..||.||||||.||||||.||
GCILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMN---QQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHP

YV
||
YV
Kinase 3210.AA MAPK 13-310 43 8.70000000001e-174 583.64 In-house 1-328 (328) Show / Hide 
Range on Protein: 13-310
Range on HMM: 1-328/328
Sequence Identity: 43% (145 aa)

YEILSKLGRGAYGIVWKVYDKR------TKQVLALKKIFDAFQNSTDAQRTFREIMFLQEL-DHENIIKVINVIRAK-----ND----RDIYVVFEYMDT
|.||...| ||||.|....|||      ...  |.|||...||| |...||.|||..|... .||||||........     |.    .|||.|.|.|.|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLHAVIR-VNILEDIHKQYIMYQIFRA--IKYIHSGELIHRDLKASNILVNSDCMVKVADFGLVRSIANQENGSTP----------ILTEYIATRWYRAP
|||..|.  ..|.|.|.||.|||| |.  .|||||.  |||||| ||||||..| .|..|||| |||.....  .            .|||.||||||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EILLGIIELSQCSHTYTKGVDMWSIGCILGQLLL-GKPIFAGTSTLNQLELILQVTGKPTYEDIEAIQ-SDLAITMLEAVQNNPTQNTKTLQQMIPM---
||.|. |     .. |||.|||||.|||.. .|  .||.| |.....|..||..|.|.|. |.|. |. |. | ....  .|.| .. |....|.|    
EIMLNWI-----WMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANF

-ASDDALDLLQNLLQFNPKKRITAEQALSHPYV
 |...|.|||. .|.|.|.||||.|.||.|||.
NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 3210.AA CMGC 13-310 25 2.6e-134 444.18 In-house 1-513 (513) Show / Hide 
Range on Protein: 13-310
Range on HMM: 1-513/513
Sequence Identity: 25% (132 aa)

YEILSKLGRGAYGIVWKVYD--------------KRTKQVLALKKIFDAFQNSTDAQ----------RTFREIMFLQEL-----------------DHEN
|||..|.|.|.||.|.| .|              ..|... |.|||. .| . ..|.          |..|||..|..|                 .|.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIKVINVIRAKN---------------DRDIYVVFEYMDTDLHAVIRVN----------ILEDIH------------KQYIM------YQIFRAIK--YI
|.| ..... ||               ....| ||||||.||. .|. |           |.. |            ..|.|      |||.|..|  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSGE--LIHRDLKASNILVNSDCMV--------------------KVADFGLVRSIANQ------------------ENGSTPILTEYIATRWYRAPEIL
||     |||||| .|||.|..| .                    |..|||| |.. .                   . ...  .|.|..||||||||||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDD-KPNRPYTHYVVTRWYRAPEIL

LGIIELSQC--SHTYTKGVDMWSIGCILGQLLLG--------KPIFA-----------GTSTLNQLELILQVTGKPT---------------YE------
||  . ...  |. ||...||||.|||.. ...|        ||.|            |.|...||..| .| |.||                |      
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

---------------DIEAIQSDLAITMLEAVQNNPTQNTKTLQQMIPM-----------------------------------ASDDALDLLQNLLQFN
               ......|. | . ..   . |... |......|                                    ....|.|||...||..
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PKKRITAEQALSHPYV
|.|||||||||.||| 
PDKRITAEQALQHPYF
Kinase 3210.AA ERK 13-310 42 3.8e-124 418.73 In-house 1-307 (307) Show / Hide 
Range on Protein: 13-310
Range on HMM: 1-307/307
Sequence Identity: 42% (134 aa)

YEILSKLGRGAYGIVWKVYDKR-----TKQVLALKKIFDAFQNSTDAQRTFREIMFLQELD-HENIIKVINVIRAK---NDRDIYVVFEYMDTDLHAVIR
|.|....|.||||.| .. ||      | |  | |||..|| .  .. || ||| .|  .. |||||. ..... .   .  |||.|.|.|.|||| .|.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIIN

VN-ILEDIHKQYIMYQIFRAIKYIHSGELIHRDLKASNILVNSDCMVKVADFGLVR----SIANQENGSTPILTEYIATRWYRAPEILLGIIELSQCSHT
    |.| | || |||| ...|||||   |||||| |||||||.|  |..|||| |    |... . .  ...|||.||||||||||.|   .       
SQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQK-------

YTKGVDMWSIGCILGQLLLGKPIFAGTSTLNQLELILQVTGKP-TYEDIEAIQSDLAITMLEAVQNNPTQNTKTLQQMIPMAS--DDALDLLQNLLQFNP
||| .|.||.|||.  .| .||.| | ....|...|.|..|.| . ||.. |.|. |  ..   .| | .  | .. ..| |.   .|.|||. .|.|.|
YTKAMDIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPN-PVRPPKPWENIFPNANCNPQAIDLLEKMLVFDP

KKRITAEQALSHPYV
.||||.|..|.||| 
DKRITVEECLEHPYF
Kinase 3210.AA p38 13-310 40 1.6e-100 340.28 In-house 1-289 (289) Show / Hide 
Range on Protein: 13-310
Range on HMM: 1-289/289
Sequence Identity: 40% (123 aa)

YEILSKLGRGAYGIVWKVYDKRTKQV---LALKKIFDAFQNSTDAQRTFREIMFLQELDHENIIKVINVIRA-----KNDRDIYVVFEYMDTDLHAVIRV
|. |. .| |||| | |..|.||.|     | ||..  ||   .| ||.||.  |. ..|||.|. ..|        .. .|.|.| . |..||. ....
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

NILEDIHKQYIMYQIFRAIKYIHSGELIHRDLKASNILVNSDCMVKVADFGLVRSIANQENGSTPILTEYIATRWYRAPEILLGIIELSQCSHTYTKGVD
  | | | |.. ||| |. ||||| . |||||| ||| || || ... |||| |. ..        .|.|.||||||||||.|  .      | ||. ||
QRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLARHCDDE-------MTGYVATRWYRAPEIMLNWM------H-YTQTVD

MWSIGCILGQLLLGKPIFAGTSTLNQLELILQVTGKPTYEDIEAIQSDLAITMLEAVQNNPTQNTKTLQQMIPMASDDALDLLQNLLQFNPKKRITAEQA
.||.|||.  |. |.. | |.  ..||. |..|.|.|. | .. |||. |      .|. |.   . .... ..|.  |.|||  .|.  | ||||||.|
IWSVGCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEA---RNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEA

LSHPYV
..||| 
MQHPYF
Kinase 3210.AA S_TKc 13-310 29 3.6e-96 326.72 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-310
Range on HMM: 1-231/231
Sequence Identity: 29% (94 aa)

YEILSKLGRGAYGIVWKVYDKRTKQVLALKKIFDAFQNSTDAQRTFREIMFLQELDHENIIKVINVIRAKNDRDIYVVFEYMDT---DLHAVIRVNI---
|||| |.|.||.| |.|...|.|... |.|.|          ... |||  |.. .|.||.| . |..     ..|.|.||.|.   ||. .|. .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LEDIHKQYIMYQIFRAIKYIHSGELIHRDLKASNILVNSDCMVKVADFGLVRSIANQENGSTPILTEYIATRWYRAPEILLGIIELSQCSHTYTK-
    .   | ...||||..|..|.||   |||||| .|||...   .|..|||| | .           | .. |.||.|||.|            |.| 
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL-----------GYGKC

GVDMWSIGCILGQLLLGKPIFAGTSTLNQLELILQVTGKPTYEDIEAIQSDLAITMLEAVQNNPTQNTKTLQQMIPMASDDALDLLQNLLQFNPKKRITA
 .|.||.||||  .| |.| |       |....... |                                        |..|.|.....||..|.||.||
KCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG----------------------------------------SPEAKDFIRKCLQKDPEKRPTA

EQALS-------HPYV
 .||        ||..
-EALQDEWDIKCHPWF
Kinase 3210.AA ERK1 13-310 45 3.4e-95 322.55 In-house 1-289 (289) Show / Hide 
Range on Protein: 13-310
Range on HMM: 1-289/289
Sequence Identity: 45% (138 aa)

YEILSKLGRGAYGIVWKVYDKRTKQVLALKKIFDAFQNSTDAQRTFREIMFLQELDHENIIKVINVIRAK---NDRDIYVVFEYMDTDLHAVIRVNILED
|  |. .| ||||.|   ||...||  |.|||   |   |  ||| |||  |.   |||||.. ..|||.   . ||.|.| . |.|||  ...   |  
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKI-SPFEHQTYCQRTLREIKILTRFKHENIINIQDIIRADTIEQMRDVYIVQCLMETDLYKLLKTQHLSN

IHKQYIMYQIFRAIKYIHSGELIHRDLKASNILVNSDCMVKVADFGLVRSIANQENGSTPILTEYIATRWYRAPEILLGIIELSQCSHTYTKGVDMWSIG
 |  | .||| | .|||||   .||||| ||.|.|  | .|. |||| | ||  |   |  ||||.||||||||||.|        |  ||| .|.||.|
DHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIML-------NSKGYTKSIDIWSVG

CILGQLLLGKPIFAGTSTLNQLELILQVTGKPTYEDIEAIQSDLAITMLEAVQNNPTQNTKTLQQMIPMASDDALDLLQNLLQFNPKKRITAEQALSHPY
|||  .|  .||| |   | || .|| | | |  .|.. |  . |   |...   | ..   .... | |   |||||. .| |||.|||| |.|| |||
CILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSL---PHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPY

V
.
L
Kinase 3210.AA CDK 13-310 33 6.2e-94 300.91 In-house 1-284 (284) Show / Hide 
Range on Protein: 13-310
Range on HMM: 1-284/284
Sequence Identity: 33% (112 aa)

YEILSKLGRGAYGIVWKVYDKRTK-----QVLALKKIF----------DAFQNSTDAQRTFREIMFLQELDHENIIKVINVIRAKN---------DRDIY
||.| |.|.|.||.| |  ||.|.     |. |||||           . |  .     . |||  |.|| |.||.|.. |.  ||         .. .|
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPIT-----AIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLY

VVFEYMDTDLHAVIRVNILEDIHKQYIMYQIFRAIKYIHSGELIHRDLKASNILVNSDCM-----VKVADFGLVRSIAN---QENGSTPILTEYIATRWY
 ||||||.||  ...         . .|.|. |.. |.||   .||||| .|||.|..       .|.||||| |   .   .. . .  .|  . |.||
MVFEYMDHDLKKYMD--------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLWY

RAPEILLGIIELSQCSHTYT--KGVDMWSIGCILGQLLL---GKPIFAGTSTLNQLELILQVTGKPTYEDIEAIQSDLAITMLEAVQNNPTQNTKTLQQM
||||.|||       | .|.   ..||||.|||.. ...   .||.| |.| ..||..| .. | || ..   . .                        
RAPELLLG-------SKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------

IPMASDDALDLLQNLLQFNPKKRITAEQALSHPYV
         |||...|...|||||.|||||.||| 
---------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 3210.AA ERK5 13-310 40 6.1e-89 301.79 In-house 1-295 (295) Show / Hide 
Range on Protein: 13-310
Range on HMM: 1-295/295
Sequence Identity: 40% (122 aa)

YEILSKLGRGAYGIVWKVYDKRTKQVLALKKIFDAFQNSTDAQRTFREIMFLQELDHENIIKVINVIRAKND----RDIYVVFEYMDTDLHAVIRVNI-L
|.|. |.| ||||.|     ... |  |.|||  ||   | |.|||||.  |.   |.||| . .... |      .|.||||. |. ||| .|  |  .
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQPF

EDIHKQYIMYQIFRAIKYIHSGELIHRDLKASNILVNSDCMVKVADFGLVRSIAN-QENGSTPILTEYIATRWYRAPEILLGIIELSQCSHTYTKGVDMW
   |  | .||| | .||.|| . |||||| ||.|||  | .|. |||. | ..    .     .|||.|||||||||...        || ||. .|.|
TLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMF-------SSHDYTQAIDVW

SIGCILGQLLLGKPIFAGTSTLNQLELILQVTGKPTYEDIEAIQSDLAITMLEAVQNNPTQNTKTLQQMIPMASDDALDLLQNLLQFNPKKRITAEQALS
|.|||.| ..  . .| |   ..||.||..| | |    |.|. .|     .    | | .  | .... | |   |||||  .| | | .|||. .|| 
SVGCIFGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQK--NFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQ

HPYV
||..
HPFL
Kinase 3210.AA Pkinase 13-310 29 1.4e-87 302.09 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-310
Range on HMM: 1-293/293
Sequence Identity: 29% (94 aa)

YEILSKLGRGAYGIVWKVYDKRTKQVLALKKIFDAFQNSTDAQRTFR--EIMFLQELDHENIIKVINVIRAKNDRDIYVVFEYMDT-----DLHAVIR--
|.|..|.|.|..| |.| ..| | .. |.|.|    ..|   |. .|  ||  ...|.|.||.. . . .   ...||.|.||..      ||...|.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

-VNIL--EDIHKQYIMYQIFRAIKYIHSGELIHRDLKASNILVNSDCMV----KVADFGLVRSIANQENGSTPILTEYIATRWYRAPEILLGIIELSQCS
  . .  .. . . .||||.|...|.||   |||||| .|||..... .    |..|||| . .    . . . .| .  |.||.|||...        .
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIR-------GG

HTYTKGVDMWSIGCILGQLLLGKPIFAGT----STLNQLELILQVTGKPTYEDIEAIQSDLAITMLEAVQNNPTQNTKTLQQMIPMASDDALDLLQNLLQ
  |.. |||||.|||| ..|.|.|.| |     . ..|...| .. |.|. .|..   |    . .   .       . ..   . .|....|.. ..|.
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----F-HWTF-HNWSEECKDFIKWCLC

FNPKKRITAEQALSHPYV
..||||.||||.| ||..
KDPKKRPTAEQILQHPWF
Kinase 3210.AA nmo 14-310 35 2.1e-80 246.85 In-house 2-292 (292) Show / Hide 
Range on Protein: 14-310
Range on HMM: 2-292/292
Sequence Identity: 35% (108 aa)

EILSKLGRGAYGIVWKVYDKRTKQVLALKKIFDAFQNSTDAQRTFREIMFLQELDHENIIKVINVIRAKND---RDIYVVFEYMDTDLHAVI-RVNILED
.    .| ||.|.|| | | |  .  ||||. . |||   ..| |||.  |    |.|..   ..... .    ..|||| | |  ||| .|     |  
QPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHKDFFQEIYVVTELMQSDLHKIIVSPQHLSS

IHKQYIMYQIFRAIKYIHSGELIHRDLKASNILVNSDCMVKVADFGLVRSIANQENGSTPILTEYIATRWYRAPEILLGIIELSQCSHTYTKGVDMWSIG
 | .  .||| | .||.|| ...|||.|  |.||||.|..|. |||| |    ..      .|. . | .|||||||.|       .. ||  ||.||.|
DHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKH---MTQEVVTQYYRAPEILMG-------ARHYTSAVDIWSVG

CILGQLLLGKPIFAGTSTLNQLELILQVTGKPTYEDIEAIQSDLAITMLEAVQNNPTQNTKTLQQMIP--MASDDALDLLQNLLQFNPKKRITAEQALSH
|| . ||  . .|   | ..||..| .. | |. ||.          || . . .|   .. | ..     |  .| .||. .| |.| ||| ...|| |
CIFAELLGRRILFQAQSPIQQLQMITDLLGTPSMEDMKYACEGAKAHMLRMPHKPPC--LQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAH

PYV
||.
PYL
Kinase 3210.AA MAPK-Unclassified 13-160 44 1.9e-57 197.17 In-house 1-159 (575) Show / Hide 
Range on Protein: 13-160
Range on HMM: 1-159/575
Sequence Identity: 44% (70 aa)

YEILSKLGRGAYGIVWKVYDKRT-KQVLALKKIFDAFQNSTDAQRTFREIMFLQELDHENIIKVINVIRAKNDRD-----IYVVFEYMDT---DLHAVIR
||    .| ||||.| .  ||.. .|  | ||.  .|.| ||. |. |||  | .| |.|||.. .....| .       ||.| .|| |   ||| .|.
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIK

VNI--LEDIHKQYIMYQIFRAIKYIHSGELIHRDLKASNILVNSDCMVKVADFGLVRSI
 |.  ....| ||..||| | .||.|| . |||||| ||.|.| || |...|||. |||
SNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSRSI
Kinase 3210.AA MAPK-Unclassified 171-310 28 4.4e-40 139.5 In-house 405-575 (575) Show / Hide 
Range on Protein: 171-310
Range on HMM: 405-575/575
Sequence Identity: 28% (52 aa)

LTEYIATRWYRAPEILLGIIELSQCSHTYTKGVDMWSIGCILGQLLLG-----------KPIFAGTS--------------------TLNQLELILQVTG
.|.|..|||||||||.|        .| |.. ||.||||||.. ...            .|.| |..                       |. .|. . |
MTQYVVTRWYRAPEIML-------SMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLG

KPTYEDIEAIQSDLAITMLEAVQNNPTQNTKTLQQMIPMASD----------DALDLLQNLLQFNPKKRITAEQALSHPYV
 |  ||.  |..| |.  ...       .     .... .            ...|..| .|||||.|||||.|||.|||.
MPPEEDCNFITCDSARKYIQSFKC---KTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase 3210.AA TyrKc 13-313 20 1.1e-14 14.66 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-280/280
Sequence Identity: 20% (68 aa)

YEILSKLGRGAYGIVWK-VYDKRTKQVLALKKIF-DAFQNSTDAQRTFREIMFLQEL--DHENIIKVINVIRAK-----NDRDIYVVFEYMDT-DLHAVI
 . . |||.||.|.|.| ...    .  | |..  ||       .   ||.  . .|  .|.||.. . |.. .      .  ...|.|||.  ||.  .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

RVNI--LEDIHKQYIMYQIFRAIKYIHSGELIHRDLKASNILVNSDCMVKVADFGLVRSIANQ-----ENGSTPI----LTEY-IATRWYRAPEILLGII
| .   |   .. ....|| .   |.||  .||||| | |.||...  ||..|||| | | .      .           . . .  ||. ||| .    
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI----

ELSQCSHTYTKGVDMWSIGCIL------GQLLLGKPI---FAGTSTLNQLELILQVTGKPTYEDIEAIQSDLAITMLEAVQNNPTQNTKTLQQMIPMASD
      ...|   | || |  .      ||     .|      .  .....        | ..  . .                           . ..|
----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MS------------------------F-VCCPD

DALDLLQNLLQFNPKKRITAEQALSHPYVRQF
.  .. .   ...|..| | ..      ...|
EMYQIMKQCWHEDPEDRPTFSEI-----HECF
Kinase 3210.AA Pkinase_Tyr 58-170 32 2.2e-14 49.32 Pfam 51-178 (270) Show / Hide 
Range on Protein: 58-170
Range on HMM: 51-178/270
Sequence Identity: 32% (41 aa)

FREIMFLQEL-DHENIIKVINVIRAKNDR-DIYVVFEYMDT-DLHAVIRVN-----ILEDIHKQYIMYQIFRAIKYIHSGELIHRDLKASNILVNSDCMV
.||.  . .| .|.||.. . |.  . .   ||.|.|||   ||.   | .      |   ..  . .|| ..  | .|  .||||| | |.||...  |
MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVV

KVADFGLVRSI-------ANQENGSTPI
|..|||| | |         ...|  ||
KICDFGLARDIYNDDYYYRKRGGGKLPI
Kinase 3210.AA Pkinase_Tyr 13-29 47 0.082699 6.75 Pfam 1-17 (270) Show / Hide 
Range on Protein: 13-29
Range on HMM: 1-17/270
Sequence Identity: 47% (8 aa)

YEILSKLGRGAYGIVWK
 ... |||.||.| |.|
ITFGKKLGEGAFGEVYK