Gene 2675 (Tetrahymena)
2675
Sequence
Protein domains of 2675.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 2675.AA | CDPK | 77-333 | 57 | 1.9e-200 | 620.16 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 77-333 Range on HMM: 1-271/271 Sequence Identity: 57% (157 aa) MILSPPLGKGAYGEVRKAIHK-ASGQLR-AIKIIKINEVSQEDK-QNLENEIDILRNLDHPNIIKIFEFYKDSNYYYIVSE--LCTGGELFDKIIEEKSF ......||||..|.|||..|| ...| | |.|||. ..|..... |.. |||.||..|||||||||.||| |...|||| | .||||||||.|||...| YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF DEFKACNIIKQVLQAVNYCHSNKIVHRDLKPENLLYDNDTPSQ----TLKVIDFGTSRYYDPE-----NKLTQRLGTPYYIAPEVLKKEYNEKCDIWSCG .|..|..|..|.|.||||||||.||||||||||.|.|.. ... ..||||.|||...|.. .|..||.|||||||||||.| ||||||||||| TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKKYNEKCDIWSCG VILYILLCGYPPFASKVDSEILEKVKLGEYNFNKPEWRHVSQDAKNLINNMLQYNPQQRYSARQCLQDKWF ||||||||||||| | |.||.|||| |.|.|..||| |.|..||.||..||.|.|..|.|| |.||..|| VILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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| Kinase | 2675.AA | CAMK1 | 78-333 | 44 | 8.4e-156 | 456.43 | In-house | 2-276 (276) | Show / Hide |
Range on Protein: 78-333 Range on HMM: 2-276/276 Sequence Identity: 44% (123 aa) ILSPPLGKGAYGEVRKAIHKAS---GQLRAIKIIK-INEVSQEDK---QNLENEIDILRN---LDHPNIIKIFEFYKDSNYYYIVSELCTGGELFDKIIE .. .|.|| .||....|| . |. |||.|. ....| ..|||||.|... .|||||||..|.| . |..|.| ||.|||||||.|.| EFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIVE EKSFDEFKACNIIKQVLQAVNYCHSNKIVHRDLKPENLLYDNDTPSQTLK--VIDFGTSRYYDPEN-KLTQRLGTPYYIAPEVLK----KEYNEKCDIWS ... | .|..|.||.|.||.|.||. ||||||||||||| . . ..| ..||| |...|... ..... |||.|.|||||. | | .||.|| KGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWS CGVILYILLCGYPPFASKV-DSEILEKVKLGEYNFNKPEWRHVSQD-AKNLINNMLQYNPQQRYSARQCLQDKWF .|||.|||||||||| .. |.|..||.| .||.| .|.| ..| ||..|..|| .|..||.. |||...|. IGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | 2675.AA | Ciliate-E2a | 83-333 | 44 | 1e-145 | 431.86 | In-house | 7-275 (275) | Show / Hide |
Range on Protein: 83-333 Range on HMM: 7-275/275 Sequence Identity: 44% (120 aa) LGKGAYGEVRKAIHKASGQL-RAIKIIKINEVSQEDKQNLENEIDILRNLDHPNIIKIFEFYKDSNYYYIVSELCTGGELFDKIIEEKSFDEF--KACNI .|||..| |..| || |. ...|.|| .... ..|....|||.|.|.||||||||..|.|.| |.||.| |.| ||||.|||.. |.|.|. ..| | IGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDI IKQVL-QAVNYCHSNKIVHRDLKPENLLYD-NDTPS---QTLKVIDFGTSRYY--DPENKLTQRLGTPYYIA------PEVLKKE-YNEKCDIWSCGVIL ..| | |...|.|...|.||||||||.|.. ... | . .|.||||..... | .... |. |||.|.| .||||.. | .|||.||||||. MQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIF YILLCGYPPFASKVDSEILEKVKLGEYNFNKPE-WRHVSQDAKNLINNMLQYNPQQRYSARQCLQDKWF ||||||.||| | .|||...| ...|| || | .|...|.|. ||...|..|..| |.|...|| YILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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| Kinase | 2675.AA | CAMK | 82-333 | 29 | 2e-135 | 439.19 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 82-333
Range on HMM: 1-425/425
Sequence Identity: 29% (124 aa)
PLGKGAYGEVRKAIHKASG------------QLRAIKIIKINEVS--------------------------QEDKQNLENEIDILRN-------LDHPNI
||.|..|.|...||| .. | |||||. . .. ..|..|...||.|... ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IKIFEFYKDSNY-------------------YYIVS---ELCTGGEL----FDKIIEEKS---------------FDEFKACNIIKQVLQAVNYCHSNKI
||..|.| |..| .|.| |.|.|||| ||.|.| .. |.| |. ...|...||.||||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
VHRDLKPENLLYDNDTPSQ--------------TLKVIDFGTSRYYDPEN------------------------KLTQRLGTPYYIA-PEVLKKE-----
|||||||||.|.|.. ... ..|.|||| ....|| . |.. . |||.|.| ||||...
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
----------YNEKCDIWSCGVILYILLCGYPPFASK-------------VDSEILEKVKLGEYNFNKPE------------WRHVSQD--------AKN
|..|||.|||||||||.||||||| .. |.|..||.. |.|.| |. | ..|.. .|.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LINNMLQYNPQQRYSARQCLQDKWF
||..|||..|..|... |||...|.
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 2675.AA | S_TKc | 77-333 | 37 | 1.7e-111 | 377.66 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 77-333 Range on HMM: 1-231/231 Sequence Identity: 37% (103 aa) MILSPPLGKGAYGEVRKAIHKASGQLRAIKIIKINEVSQEDKQNLENEIDILRNLDHPNIIKIFEFYKDSNYYYIVSELCTG--GELFDKIIEEKS---- . ..||||.|.|.|..|| .|.. |||||| .....||.||.. .||||.|..... | ...|.| |.| | |.||| | . .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --FDEFKACNIIKQVLQAVNYCHSNKIVHRDLKPENLLYDNDTPSQTLKVIDFGTSRYYDPENKLTQRLGTPYYIAPEVLKKEYNE-KCDIWSCGVILYI |.| |. ...|...|..||||..|.||||||||.| |. ..|..||| .| . | |||.|.||||| |. |||.||||.|||. FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYE LLCGYPPFASKVDSEILEKVKLGEYNFNKPEWRHVSQDAKNLINNMLQYNPQQRYSARQCLQ-------DKWF .||||||| . ....|.. |..||..|...||..|..|..| ..|| . || MLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 2675.AA | CAMKL | 76-333 | 36 | 1.2e-108 | 347.82 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 76-333 Range on HMM: 1-297/297 Sequence Identity: 36% (111 aa) YMILSPPLGKGAYGEVRKAIH-KASGQLRAIKIIKINEVS--------------QEDKQNLENEIDILRNLD---HPNIIKIFEFYKDSNY------YYI | |. ||||..|.|. |.| . |. |||||... . . |. ... || |.. |. ||||||..| . .... .|. YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYL VSELCTGGE--LFDKIIEE----KSFDEFKACNIIKQVLQAVNYCHSNKIVHRDLKPENLLYDNDTPSQTLKVIDFGTSRYYDP-----ENKLTQRLGTP | |.| ||| |||.|... ....| |. . .|.. |||||||..|||||.||||.| |.. . ..|.|||| | .|.| ..||. . |.| VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP YYIAPEVLKK--E-YN-EKCDIWSCGVILYILLCGYPPFA------SKVDSEILEKVKLGEYNFNKPEWRHVSQDAKNLINNMLQYNPQQRYSARQCLQD | |||.... . |. | |||||||||| ..||| || ..| ... | . .. | | ||| |...|| ||| || .|... | ... PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH KWF .|. PWM |
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| Kinase | 2675.AA | Pkinase | 77-333 | 33 | 1e-102 | 352.36 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 77-333 Range on HMM: 1-293/293 Sequence Identity: 33% (98 aa) MILSPPLGKGAYGEVRKAIHKASGQLRAIKIIKINEVSQEDKQNLEN--EIDILRNLDHPNIIKIFEFYKDSNYYYIVSELCTGG----ELFDKII--EE . ..|.|..|.|.|..|| .|.. |.|||| . . . .|.. . || |...|.||||....... |....|.| |.| || .||| | .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH KSF--DEFKACNIIKQVLQAVNYCHSNKIVHRDLKPENLLYD-NDTPSQTLKVIDFGTSRY--YDPENKLTQRLGTPYYIAPEVLK--KEYNEKCDIWSC ..| .| ......|.|....||||..|.||||||||.|.| |.... ..|..||| .. | . .| . |||.|.||||.. ..| |.|.||| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVILYILLCGYPPFASK------VDSEILEKVKLGEYNFNKPEWRHVS-----------------QDAKNLINNMLQYNPQQRYSARQCLQDKWF |.|||..|||.||| .. . ....... ... |. |.|. .| ...| .|...|...|..|..|.|.||..|| GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 2675.AA | Ciliate-E2 | 77-333 | 27 | 1.8e-102 | 346.7 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 77-333 Range on HMM: 1-365/365 Sequence Identity: 27% (106 aa) MILSPPLGKGAYGEVRKAIHKASGQLR------------------AIKIIKINEVSQEDKQNLENEIDILR----------------NLDHPNIIKIFEF .. .|.|..| |.|. .. ... .|||. .. ... .......||.|.| .|.||||||..|. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YK--DSNYYYIVSELCTGGELFDKII------------EEKSFDEFKACNIIKQVLQ---------------AVNYCHSNK-IVHRDLKPENLLYDNDTP .. | |..|.| |.| ||.||| |. . |.|.|.....|.||.|| |..|.||.. |.|||.||||.|. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- SQTLKVIDFGTSRYYDPE----------NKLTQRL-----------------------GTPYYIAPEVLK----------KEYNEKCDIWSCGVILYILL .|.||||.|..||.. ..... |||.| |||.|. |.|..||||||.|||||..| ---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML CGYPPFASKVDSEILEKVKLGEYNFNKPE--------------WRHVSQDAKNLINN----MLQYNPQQRYS-ARQCLQDKWF .|.||| ... | ....|..|| | ..||..|.||.. |||..|..|.. . |.|. .|| FGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 2675.AA | RAD53 | 78-333 | 35 | 3e-102 | 305.4 | In-house | 2-305 (305) | Show / Hide |
Range on Protein: 78-333
Range on HMM: 2-305/305
Sequence Identity: 35% (108 aa)
ILSPPLGKGAYGEVRKAIHKASGQLRAIKIIKI---N---EVSQEDKQNLENEIDILRNLDHPNIIKIFEFYKD-SNYYYIVSELCTGGELFDKIIEEKS
..| ||.|..|.|..|. | .| |||||. . .. .. ...||. ||..| ||.||.|.... . . |||.| || ||||||.||. |
YMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNKR
----FDEFKACNIIKQVLQAVNYCHSNKIVHRDLKPENLLYDNDTPSQ---------------TLKVIDFGTSRYYDPENKLTQRL-GTPYYIAPEVLKK
||| .. . .| . ||.| |.| |.|||||||| |.... . .|. ||| |. . | ... . ||| | ||||. .
CQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVG-EGSFMKTMCGTPQYVAPEVITS
----------------EYNEKCDIWSCGVILYILLCGYPPFA-SKVD----SEILEKVKL-GEYNFNKPEWRHVSQDAKNLINNMLQYNPQQRYSARQCL
.|. |.|.|| |.||||.||||||| .. . . |..| | |.| .|.|. .|. ||.||..||. .| ||.. . |
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL
QDKWF
. |.
NHPWM
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| Kinase | 2675.AA | CAMK-Unique | 77-333 | 26 | 4.5e-100 | 331.07 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 77-333
Range on HMM: 1-363/363
Sequence Identity: 26% (97 aa)
MILSPPLGKGAYGEVRKAIHKASGQLRAIKIIKINEVSQEDKQN------------------LENEIDILRNLDHPNIIKIFEF----YKDSN-------
.. ..|.|..|.|.... .. | ..|.|..| .. . . |..|..|.. .|||||||.... . |..
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------YYYIVSELCTGGELFDKIIE--------------------EKSFDE--FKACNIIKQVLQAVNYCHSNKIVHRDLKPENLLYDNDTP-----
|.||| |.|.||.|||.|.. . .| | .|.|. ..|.||.| ||..|||||||.||... . .
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
--------SQTLKVIDFGTSRYYDPENKLT---QRLGTPYYIAP--------------EVLK-KEYNEKC----DIWSCGVILYILLCGYPPFASKVDS-
.|..||| ...|. . . . |||.|.|| ||.. | ..| ||||.|||.|..|||.|||.. ..
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR
-------EILEKVKLGEY-NFNKPEWRH---VSQDAKNLINNMLQYNPQQRYSARQCLQDKWF
||.|. . |.| || .. |. .|| ||... . ... | .| || . |. |.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | 2675.AA | RSK | 78-333 | 32 | 1.2e-84 | 287.47 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 78-333 Range on HMM: 1-278/278 Sequence Identity: 32% (91 aa) ILSP-PLGKGAYGEVRKAIHKASGQLRAIKIIKINEVSQEDK--QNLENEIDILRNLD-HPNIIKIFEFYKDSNYYYIVSELCTGGELFDKIIEEKS--- . ..|.|.. .|| .|...||. | |..| ... | .| |..|| ||.|.. .. ... . |.. |.| |||||... .||. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FDEFKACNIIKQVLQAVNYCHSNKIVHRDLKPENLLYDNDTPS-QTLKVIDFGTSRYYDPE-NKLTQR-LGTPYYIAPEVLK----KE-YNEKCDIWSCG |.| || .. .. || . |. .|.|||||||| |||... . ..|..||| ... ... |..|. .| |.|||.|| .. ... ||.|| | FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG VILYILLCGYPPFAS---KVDSEILEKVKLGEYNFNKPEWRHVSQDAKNLINNMLQYNPQQRYS-----ARQCLQDKWF |..| .| |.|||.. . .||..... |..... |.| .||.||.||. ||. .|..|.. | . .|..|| VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 2675.AA | Ciliate-E2-Unclassified | 76-333 | 30 | 6.2e-84 | 285.16 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 76-333
Range on HMM: 1-352/352
Sequence Identity: 30% (107 aa)
YMILSPPLGKGAYGEVRKAIHKASGQLRAIKIIK-INEVSQEDKQNL---------ENEID-------------ILRNLDHPNIIKIFEFYKDSNYYYIV
| |. .|.|..|.|.|..|| .|. |.|..| |....| ..| .|.. ||.|..||.|.| |. .| .. |||
YKIIK-QIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV
SELCTGGELFDKIIEEKS-----------------FDEFKAC-----NIIKQVLQAVNYCHSNK-IVHRDLKPENLLYDNDTPSQTLKVIDFGTSRYYD-
|.| ||.|.. | . |. |.|..|. ....|.||. .|.|... |.|||.||||.|.||. .|.|||| |..|.
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ
---------------PENKLTQRLGTPYYI----APEVLKK-EYN----EKCDIWSCGVILYILLCGYPPFASKVDSE----------------ILEKVK
........ |||.|. |||||.. .|. .||||||.||||| .| ||.|| .. . . .... |
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK
LGEYNFNKPEW----RHVSQDAKNLIN----NMLQYNPQQRYSARQCLQDKWF
....|.| .| |.|. ||..|| ||..|| .|... | |. ||
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 2675.AA | TyrKc | 77-332 | 22 | 3.5e-19 | 70.95 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 77-332 Range on HMM: 1-280/280 Sequence Identity: 22% (66 aa) MILSPPLGKGAYGEVRKAIHKASGQLRAIKIIKINEVSQEDKQNLENEIDILRNL--DHPNIIKIFEFYKDS-------NYYYIVSELCTGGELFDKIIE | || ||.|||.|.. | . |.| .| . .. . .|. |...| .||||.... .. ..|| |.. .| | | . . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK EKS-FDEFKACNIIKQVLQAVNYCHSNKIVHRDLKPENLLYDNDTPSQTLKVIDFGTSRYYDPE-----NKLTQRL----GTP-----YYIAPEVL-KKE . . . ... |. . .| ||....|||| | |.... | |. ||| ||. . . .| . | |. |||.. ... HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK YNEKCDIWSCGVILY-ILLCGYPPFAS-----KVDSEILEKVKLGEYNFNKPE-----WRHVSQDAKNLINNMLQYNPQQRYSARQCLQDKW ...| |.|| || .. |. | .| . ..|..|.|| |.. |. . ... ... ...| .| . ... ... FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF |
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| Kinase | 2675.AA | Pkinase_Tyr | 77-200 | 24 | 8.8e-14 | 47.3 | Pfam | 1-137 (270) | Show / Hide |
Range on Protein: 77-200 Range on HMM: 1-137/270 Sequence Identity: 24% (34 aa) MILSPPLGKGAYGEVRKAIHK----ASGQLRAIKIIKINEVSQED--KQNLENEIDILRNL-DHPNIIKIFEFYK-DSNY--YYIVSELCTGGELFDKII .. ||.||.|||.|.. | .. |.|..| ..|. .. . .|. |...| .||||.. .. .||| |.. .| | | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR E----EKSFDEFKACNIIKQVLQAVNYCHSNKIVHRDL . ..... ... |. .. .| .|....|||| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |
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| Kinase | 2675.AA | APH | 195-229 | 26 | 0.000404 | 14.93 | Pfam | 172-207 (248) | Show / Hide |
Range on Protein: 195-229 Range on HMM: 172-207/248 Sequence Identity: 26% (10 aa) IVHRDLKPENLLYDNDTPSQTLK---VIDFGTSRYYDP ..|.|..| |...| ... . |||...... || WCHGDFHPGNVMWDP--RPDGGRVTGVIDWDDACWGDP |
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| Kinase | 2675.AA | Pkinase_Tyr | 244-288 | 26 | 4.443096 | 0.89 | Pfam | 182-230 (270) | Show / Hide |
Range on Protein: 244-288 Range on HMM: 182-230/270 Sequence Identity: 26% (13 aa) APE-VLKKEYNEKCDIWSCGVILYILLC-GYPP-FASKVDSEILEKV-K ||| .....| |.|| || .. .. | | .. ..|..|.. . APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYE |
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| Efhand | 2675.AA | efhand | 383-411 | 37 | 5e-06 | 26.55 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 383-411 Range on HMM: 1-29/29 Sequence Identity: 37% (11 aa) QLLKTFKQLDTDGDGMLSQQELLNGYKKI .| . ||..|.|||| .. .|.....||. ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 2675.AA | EFh | 383-411 | 27 | 9e-06 | 26.45 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 383-411 Range on HMM: 1-29/29 Sequence Identity: 27% (8 aa) QLLKTFKQLDTDGDGMLSQQELLNGYKKI .. . |. .|.|||| .. .|.. . |.. EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 2675.AA | efhand | 420-444 | 36 | 2e-06 | 28.2 | Pfam | 1-25 (29) | Show / Hide |
Range on Protein: 420-444 Range on HMM: 1-25/29 Sequence Identity: 36% (9 aa) EVKKIMDQVDKNKSGKIDYSEFVMA |.|......||...|.||. ||. . ELKEMFKEFDKDGDGYIDFEEFCEM |
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| EFh | 2675.AA | EFh | 420-448 | 31 | 3e-05 | 24.69 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 420-448 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) EVKKIMDQVDKNKSGKIDYSEFVMATCNR |.|.... .||...|.||. ||... . EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 2675.AA | efhand | 456-484 | 31 | 6e-07 | 29.85 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 456-484 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) KLQMAFKMFDKDNNGSLTVDEIRKLFNSH .|. .||.||||..| ....| .... . ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 2675.AA | EFh | 456-484 | 31 | 3e-06 | 28.0 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 456-484 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) KLQMAFKMFDKDNNGSLTVDEIRKLFNSH .....|.|||||..| .. .| .... | EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| EFh | 2675.AA | EFh | 490-518 | 44 | 7.2e-09 | 36.7 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 490-518 Range on HMM: 1-29/29 Sequence Identity: 44% (13 aa) VIKDIIKEVDKNQDGQISFAEFRDMMLNL .|......||. ||.|.| ||.||| .| EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 2675.AA | efhand | 490-518 | 48 | 8e-09 | 36.7 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 490-518 Range on HMM: 1-29/29 Sequence Identity: 48% (14 aa) VIKDIIKEVDKNQDGQISFAEFRDMMLNL .|...||.||..||.|.| ||..|| .| ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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