Gene 18013 (Tetrahymena)

18013

Species: Tetrahymena
Alias: 3796.m00118, PreTt18013, 18013, 271, 260.m00020, TTHERM_01164090
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CDPK

Sequence

Name Sequence Type Origin Length Description Download
18013.AA Protein None 466 None Fasta, JSON
18013.kin_dom Protein Kinase Domain None 254 None Fasta, JSON
18013.NA RNA None 1401 None Fasta, JSON

Protein domain

Protein domains of 18013.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 18013.AA CDPK 28-281 55 4.3e-202 625.33 In-house 1-271 (271) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-271/271
Sequence Identity: 55% (151 aa)

FDTRKILGSGTYGNVYKAKKK-DSKIVR-AVKQIPKSKVKNAE---RFKREIEIMRTLDHPNIIKLYETFEDERNIYLVME--VCEGGELFDRIIEKGRF
..  |.||.|..| |.|.|.|  ....| |.|.||||.||..|   .|..||||...||||||||.||...||.|.|.|||  .|.||||||.|||||.|
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

TEIEARSIFSQIMQAINYCHNNGIAHRDLKPENFLFLTKHDDS----PIKVIDFGLSKNFDNK-----QAMKTKAGTPYYISPEVLEGNYDESCDIWSAG
||.||..|. ||..|.||||.|.| ||||||||.||..|.|||    .|||||.|.||.|| .     . |....||||||.||||...|.|.|||||.|
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKKYNEKCDIWSCG

VILYILLSGVPPFFGDDDSEILASVKKGFYTFDIPEFEGISNSAKDLIQNMVTK-PEKRFKADQVLSHPWM
|||||||.|.|||.|. |.||...|||| |.|..||.. ||..|||||..| .. |.||..|.|.| |||.
VILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 18013.AA CAMK1 26-281 47 3.2e-149 436.97 In-house 1-276 (276) Show / Hide 
Range on Protein: 26-281
Range on HMM: 1-276/276
Sequence Identity: 47% (131 aa)

YEFDTRKILGSGTYGNVYKAKKKDS---KIVRAVKQIP-KSKVKNA-----ERFKREIEIMRT---LDHPNIIKLYETFEDERNIYLVMEVCEGGELFDR
|||  .|..|.|. . ||....|..   .   |.| |  |. .|.      |....|||||..   .|||||||.|| .|... .||||| . |||||||
YEF--GKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDR

IIEKGRFTEIEARSIFSQIMQAINYCHNNGIAHRDLKPENFLFLTKHDDSPIK--VIDFGLSKNFDNKQ-AMKTKAGTPYYISPEVLEG----NYDESCD
|.||| .|| .|| |  || .|..|.| .||.|||||||| |. .| .||.||  ..|||||| ||..   |||  |||.|. |||||.     || .||
IVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACD

IWSAGVILYILLSGVPPFFGDD-DSEILASVKKGFYTFDIPEFEGISNS-AKDLIQNM-VTKPEKRFKADQVLSHPWM
.||.|||.|||| | |||.... |.|... .||. |.|. |..  ||.. |||.| .| .  |.||. ..|.| ||| 
MWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 18013.AA Ciliate-E2a 28-281 46 4.6e-136 402.98 In-house 1-275 (275) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-275/275
Sequence Identity: 46% (128 aa)

FDTRKILGSGTYGNVYKAKKKDSKIVRAVKQIPKSKVKNAE----RFKREIEIMRTLDHPNIIKLYETFEDERNIYLVMEVCEGGELFDRIIEKGRFTEI
... |..|.|..| ||.|..|. .  .|.| . | |  . .     |..|| |||.|||||||||||..|||.|.||||| ||||||.|.|....||.| 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--EARSIFSQIM-QAINYCHNNGIAHRDLKPENFLFL--TKHDD--SPIKVIDFGLSKNF--DNKQAMKTKAGTPYYIS------PEVLEGN-YDESCDI
  |...|  |.  |...|.|...| ||||||||.||    | ..  | ||.|||||....  | |. |..| |||.|.       .|||... ||..||.
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WSAGVILYILLSGVPPFFGDDDSEILASVKKGFYTFDIPE-FEGISNSAKDLIQNMVTK-PEKRFKADQVLSHPWM
||.|||.||||.| ||| | . .||| ..||  . |..|| .| .|...|||.. |. | |.||..| | | |||.
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 18013.AA CAMK 33-281 32 8.99999999999e-134 433.74 In-house 1-425 (425) Show / Hide 
Range on Protein: 33-281
Range on HMM: 1-425/425
Sequence Identity: 32% (136 aa)

ILGSGTYGNVYKAKKKDSK------------IVRAVKQIPKSKVK----------------------------NAERFKREIEIMRT-------LDHPNI
.||.|..| |.... | ..               |.| |.|.|.|                            . ....||||||..       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLYETFED-------------------ERNIYLVM---EVCEGGEL----FDRIIEK---------------GRFTEIEARSIFSQIMQAINYCHNNGI
|||||..||                   ....|.||   | |.||||    ||.|.|.               ||||| ||| .| || .|..|||...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKPENFLFLTKHDDSP--------------IKVIDFGLSKNFDN------------------------KQAMKTKAGTPYYIS-PEVLEGN-----
.|||||||| |. ...|||.              ||.||||... ||                          | |||  |||.|.. ||||.|.     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------YDESCDIWSAGVILYILLSGVPPFFGD-------------DDSEILASVKKGFYTFDIPEFEG------------ISNS--------AKD
          |...||.||.||||||.|.| ||| ||             .|.|..  ..|| |.|. |.| .            ||..        .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIQNMVTK-PEKRFKADQVLSHPWM
||..| .. ||||....|.|.||||
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 18013.AA RAD53 28-281 35 1.5e-108 324.5 In-house 1-305 (305) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-305/305
Sequence Identity: 35% (108 aa)

FDTRKILGSGTYGNVYKAKKKDSKIVRAVKQIPK-------SKV-KNAERFKREIEIMRTLDHPNIIKLYETFED-ERNIYLVMEVCEGGELFDRII-EK
....|.|||| .| |..|..|.   . |.|.| |       ... |..... .|.||.. | ||.||..|. |.. ... |.|.|  .|||||..|.  |
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

GR---FTEIEARSIFSQIMQAINYCHNNGIAHRDLKPENFLFLTKHDDS---------------PIKVIDFGLSKNFDNKQAMKTKAGTPYYISPEVLE-
..   |.| ... .| |.  |..| |.|||.|||||||| |. .. ..                 ||. ||||||. .... |||  ||| |  |||.  
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

---------------GNYDESCDIWSAGVILYILLSGVPPFF-GDDD----SEILASVKK-GFYTFDIPEFEGISNSAKDLIQNMVT-KPEKRFKADQVL
               . |  ..|.||.|.||||.|.| |||  ....      .  ..|. | | |. |.   ||..|||||..| .  ||||. .|..|
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

SHPWM
.||||
NHPWM
Kinase 18013.AA S_TKc 28-281 37 2.9e-107 363.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-231/231
Sequence Identity: 37% (101 aa)

FDTRKILGSGTYGNVYKAKKKDSKIVRAVKQIPKSKVKNAERFKREIEIMRTLDHPNIIKLYETFEDERNIYLVMEVCEG--GELFDRIIEKGR------
..  ...|.|..| |||...|... . |.|.|.       |...|||.|..  .||||.|||..|.|  ..|.||| |.|  |.|||.| ..||      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FTEIEARSIFSQIMQAINYCHNNGIAHRDLKPENFLFLTKHDDSPIKVIDFGLSKNFDNKQAMKTKAGTPYYISPEVLEGNYDE-SCDIWSAGVILYILL
|.| .||... || .|..|||..|| |||||||| |. .      ||..||||.. .      .|  |||.|..||||   |.  .||.|| |.|||..|
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEML

SGVPPFFGDDDSEILASVKKGFYTFDIPEFEGISNSAKDLIQNMVT-KPEKRFKADQVLS-------HPWM
.| |||   .. ...  ..              | .|||.|... .  ||||  | ..|        |||.
CGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 18013.AA CAMKL 28-281 37 5.8e-104 332.67 In-house 1-297 (297) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-297/297
Sequence Identity: 37% (114 aa)

FDTRKILGSGTYGNVYKAKK-KDSKIVRAVKQIPKSKVKN---AERF------------KREIEIMRTLD---HPNIIKLYETFEDERN------IYLVM
..  | || |..| |  |.  .  ..  |.| | |.| .|   ...             .|||.||. |.   |||||||||..|....      |||||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EVCEGGE--LFDRIIEK----GRFTEIEARSIFSQIMQAINYCHNNGIAHRDLKPENFLFLTKHDDSPIKVIDFGLSKNFDN-----KQAMKTKAGTPYY
| |.|||  |||.|...    ||..| ||| .| ||. |.||||..||.|||.|||| |.  ...   ||.||||.|  ...      | .||  |.| |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ISPEVLEG--N-YD-ESCDIWSAGVILYILLSGVPPFFGDDD------SEILASVKKGFYTFDIPEFEGISNSAKDLIQNMVTK-PEKRFKADQVLSHPW
 .||...|    ||    ||||.||||| .. |  || .|..         .   |.    . .| .  .| ...|||. | .. ||||....|...|||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

M
|
M
Kinase 18013.AA Ciliate-E2 28-281 29 1.7e-102 346.84 In-house 1-365 (365) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-365/365
Sequence Identity: 29% (113 aa)

FDTRKILGSGTYGNVYKAKK-----------------------KDSKIVRAVKQIPKSKVKNAERFKREIE-------------IMRTLDHPNIIKLYET
..  |..|.|..| |||.|.                       |. .   |.|.. |..... .. ....              |...|.||||||.||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--DERNIYLVMEVCEGGELFDRIIEK-----------GRFTEIEARSIFSQIMQ---------------AINYCHNNG-IAHRDLKPENFLFLTKHDD
|.  |. ||||||| |.||.|||.|...           ..||| |.. |. || |               |..|.|... | |||.|||| ||      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

SPIKVIDFGLSKNFDNK--------------------------------QAMKTKAGTPYYISPEVLEGN----------YDESCDIWSAGVILYILLSG
  ||.|||||||..|..                                .  .| .|||.| .||.|.|           ||..|||||.|||||..|.|
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

VPPFFGDDDSEILASVKKGFYTFDIPE--------------FEGISNSAKDLIQN-----MVTKPEKRFK-ADQVLSHPWM
 |||        .   |.. . |. ||              .. .|...||||..     .. .||||.  ..|.| |||.
KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 18013.AA CAMK-Unique 28-281 27 5.5e-97 320.72 In-house 1-363 (363) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-363/363
Sequence Identity: 27% (100 aa)

FDTRKILGSGTYGNVYKAKKKDSKIVRAVKQIPKSKVK-NAERF-------------------KREIEIMRTLDHPNIIKLYET----FEDER-------
 .. .|.|.|..| ||... .  .  .|.| . | ... ..                      |||..|....|||||||||..    |.|..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------NIYLVMEVCEGGELFDRIIE--------------------KGRFTE--IEARSIFSQIMQAINYCHNNGIAHRDLKPENFLFLTKHD-----
        ..|.||| |.||.||| |..                    .|.|.|   ....|. .. .|..| |...| |||||.|| .. .  .     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------DSPIKVIDFGLSKNFDNKQAMK---TKAGTPYYISP--------------EVLE-GNYDESC----DIWSAGVILYILLSGVPPFFGDDDS-
        .. ||..||||.. ......     |  |||.|..|              ||..   ||. |    |||| |||.|..|.| ||| ....  
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------EILASVKKGFY-TFDIPEFEG---ISNSAKDLIQN-MVTKPEKRFKADQVLSHPWM
       ||... .|| | .|| . ..|   ||..|||.... |...| .| .| . |.|.| 
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 18013.AA Pkinase 28-281 37 1.1e-96 332.26 Pfam 1-293 (293) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-293/293
Sequence Identity: 37% (112 aa)

FDTRKILGSGTYGNVYKAKKKDSKIVRAVKQIPKSKVKNAER--FKR--EIEIMRTLDHPNIIKLYETFEDERNIYLVMEVCEGG----ELFDRII--EK
. . ...|||..| |||...|.. .. |||.|.|.. |  ..    |  ||.||. |.||||..||..|||...||.||| ||||    .|||.|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRF--TEIEARSIFSQIMQAINYCHNNGIAHRDLKPENFLFL-TKHDDSPIKVIDFGLSKN--FDNKQAMKTKAGTPYYISPEVLE--GNYDESCDIWSA
|.|  .| |..... || ....|||..|| ||||||||.|.  . | |...|..||||.|     |.. |.| .|||.|..|||.     |. ..|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYILLSGVPPFFGD------DDSEILASVKKGFYTFDIPEFEGIS-----------------NSAKDLIQNM-VTKPEKRFKADQVLSHPWM
|.|||..|.| ||| |.      |. .... .... . ||.|.   ||                  ..||.| ..   .|.||  |.|.| |||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 18013.AA MAPKAPK 30-281 34 1.2e-96 299.72 In-house 3-292 (292) Show / Hide 
Range on Protein: 30-281
Range on HMM: 3-292/292
Sequence Identity: 34% (100 aa)

TRKILGSGTYGNVYKAKKKDSKIVRAVKQIPKSKVKNAERFKREIEI-MRTLDHPNIIKLYETFED----ERNIYLVMEVCEGGELFDRIIE--KGRFTE
....||.| || | ....| .    ||| . ...    ..  || |. ... .||||... . ||.    ... |||||  ||||||..| .  ...|||
WKEVLGEGIYGKVQTCVHKRTGQEYAVKILEDQPGHSRQKARREVELHWHCQGHPNIVQIIDWFENMYQFDKCFYLVMECMEGGELFQHIQQRGHKHFTE

IEARSIFSQIMQAINYCHNNGIAHRDLKPENFLFLTKHDDSPIKVIDFGLSKN-------FDN--KQAMKTKAGTPYYISPEVLEGN-----YDESCDIW
 ||. |  .| .|. ..|. .|||||||||| |. .. ...|.|  |||. |         .   .....|  .||||. |||..       || |||.|
REASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCPVKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFKEAHTYDKSCDMW

SAGVILYILLSGVPPFFGDDD-----SE-----------ILASVKKGFYTFDIPEFEGISNSAKDLIQNM-VTKPEKRFKADQVLSHPWM
| |||.||.|.| ||| .. .                    .. ..| |.|  .| . ||. ||||| .. ...|..|  . ||..||| 
SLGVIMYIMLCGYPPFYSNCGDEDCSWDRGEACRDCQNMMFHRIQEGQYEFPDEEWSHISEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase 18013.AA RSK 31-281 34 5.8e-88 298.55 In-house 1-278 (278) Show / Hide 
Range on Protein: 31-281
Range on HMM: 1-278/278
Sequence Identity: 34% (97 aa)

RKILGSGTYGNVYKAKKK---DSKIVRAVKQIPKSKVKNA----ERFKREIEIMRTLD-HPNIIKLYETFEDERNIYLVMEVCEGGELFDRIIEKGR---
 | || | || |.  .|.   |.. . |.|.. |.|....    .. ..|..|. .   ||.|..|...|..|  .||.|| |.|||||... ....   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTEIEARSIFSQIMQAINYCHNNGIAHRDLKPENFLFLTKHDD-SPIKVIDFGLSKNF--DNKQAMKTKAGTPYYISPEVLE----GN-YDESCDIWSAG
|.| ||. ....|  |. . |  || |||||||| |.  .  .   ||..|||..| |  |..| ..|  .|  |. ||.|     .. .|..||.|| |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VILYILLSGVPPFFG---DDDSEILASVKKGFYTFDIPEFEGISNSAKDLIQNMVTK-PEKRFK-----ADQVLSHPWM
|..| .|.| ||| |   .. .||.. ..|| .....|. . .|. |||||. | .. |.|| .     |.....|||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 18013.AA Pkinase_Tyr 28-149 32 1.6e-17 59.94 Pfam 1-137 (270) Show / Hide 
Range on Protein: 28-149
Range on HMM: 1-137/270
Sequence Identity: 32% (44 aa)

FDTRKILGSGTYGNVYKAKKK----DSKIVRAVKQIPKSKVKNA---ERFKREIEIMRTL-DHPNIIKLYETFE-DERN--IYLVMEVCEGGELFDRIIE
    | ||.| .|.|||.. |    . ||  ||| .. .  . .   | | ||..||..| .||||..||     ...   ||.||| ...| | |   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----KGRFTEIEARSIFSQIMQAINYCHNNGIAHRDL
    |...|  .  ..  || .. .| ..... ||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 18013.AA TyrKc 28-281 25 2.1e-16 42.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 28-281
Range on HMM: 1-280/280
Sequence Identity: 25% (76 aa)

FDTRKILGSGTYGNVYKAKKKDSKIVRAVKQIPKSKVKNAERFKREIEIMRTL--DHPNIIKLYETFEDE-------RNIYLVMEVCEGGELFDRIIEKG
    |.||.| .| |||.. |   |  ||| . ...    | | ||..||. |  .||||..||    ..         ...||| ...| | |.. ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

R-FTEIEARSIFSQIMQAINYCHNNGIAHRDLKPENFLFLTKHDDSPIKVIDFGLSKNFDNK-------QAMKTKA--GTP-----YYISPEVL-EGNYD
. ..  .  |.  || .  .| | ... ||||   | |   .|    .|. |||||.. ...       .  ..|   |.         .||.. .| . 
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

ESCDIWSAGVILY-ILLSGVPPFFG-----DDDSEILASVKKGFYTFDIPE-----FEGISNSAKDLIQNMVT----KPEKRFKADQVLSHPWM
.  |.|| || .. |.  | .|  |      ...|... ||.|..    |.     |       ... | | .    .||.|    ..  |  .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Efhand 18013.AA efhand 327-355 31 2e-06 28.15 Pfam 1-29 (29) Show / Hide 
Range on Protein: 327-355
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

DLGKLFRQLDKNGDGTLTVDEIREGLAGT
.| ..|...||.|||.....| .|... .
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 18013.AA EFh 327-355 27 2.5e-05 24.96 SMART 1-29 (29) Show / Hide 
Range on Protein: 327-355
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

DLGKLFRQLDKNGDGTLTVDEIREGLAGT
.. ..|| .||.|||... .| .....  
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
EFh 18013.AA EFh 362-390 31 3.9e-07 30.96 SMART 1-29 (29) Show / Hide 
Range on Protein: 362-390
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

EVRKVISSIDTDGSGKIDYTEFLAATMEK
|...... .|.||.|.||. ||... ...
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 18013.AA efhand 362-390 31 6.2e-07 29.79 Pfam 1-29 (29) Show / Hide 
Range on Protein: 362-390
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

EVRKVISSIDTDGSGKIDYTEFLAATMEK
|...... .|.||.|.||. ||... ...
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 18013.AA EFh 398-426 34 9.3e-09 36.34 SMART 1-29 (29) Show / Hide 
Range on Protein: 398-426
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

KLHQAFKMLDIDGNGKISKEELKQILGKE
.. ..|.|.| ||.|.|..||.|... . 
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 18013.AA efhand 398-426 37 4.8e-08 33.87 Pfam 1-29 (29) Show / Hide 
Range on Protein: 398-426
Range on HMM: 1-29/29
Sequence Identity: 37% (11 aa)

KLHQAFKMLDIDGNGKISKEELKQILGKE
.| ..||..| ||.|.|..||..... | 
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 18013.AA EFh 434-462 44 6.8e-10 40.12 SMART 1-29 (29) Show / Hide 
Range on Protein: 434-462
Range on HMM: 1-29/29
Sequence Identity: 44% (13 aa)

YWDNMIKEVDKNGDGEIDYNEFIDMMNTI
 .. |....||.|||.||..||.||| ..
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 18013.AA efhand 434-462 48 4.7e-09 37.55 Pfam 1-29 (29) Show / Hide 
Range on Protein: 434-462
Range on HMM: 1-29/29
Sequence Identity: 48% (14 aa)

YWDNMIKEVDKNGDGEIDYNEFIDMMNTI
 ...|.||.||.|||.||..||..|| ..
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL