Gene 4112 (Tetrahymena)

4112

Species: Tetrahymena
Alias: 3675.m00056, TTHERM_00585050, PreTt04112, 80.m00158, 4112, 688
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
4112.AA Protein None 1210 None Fasta, JSON
4112.kin_dom Protein Kinase Domain None 146 None Fasta, JSON
4112.NA RNA None 3633 None Fasta, JSON

Protein domain

Protein domains of 4112.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 4112.AA HisKA 467-534 34 5.6e-09 34.28 Pfam 1-69 (69) Show / Hide 
Range on Protein: 467-534
Range on HMM: 1-69/69
Sequence Identity: 34% (24 aa)

YKKKILSSVSHELKTPLNCSIQLLDLLYQSDTIDEIQ-KKMFIEPALNSNQLLLCMINDILDFALIEKG
 |.. |...||||.|||.  . ...||  ... |. |  . ..| .... | .. .|||.|||. || |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 4112.AA HisKA 467-534 24 1.2e-08 35.97 SMART 1-89 (89) Show / Hide 
Range on Protein: 467-534
Range on HMM: 1-89/89
Sequence Identity: 24% (22 aa)

YKKKILSSVSHELKTPLNCSIQLLDLLYQ---------SDTIDEIQK------------KMFIEPALNSNQLLLCMINDILDFALIEKG
 | . |...||||.|||.  . ...||           ... |. |             . ..| .... . .. .|||.||.. || |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 4112.AA HisK 581-726 38 1.7e-60 207.26 In-house 1-164 (164) Show / Hide 
Range on Protein: 581-726
Range on HMM: 1-164/164
Sequence Identity: 38% (69 aa)

SDEMRVKQVVISLLSNAIKFTQYG------SISINVDCILLHNP------------------PQAATEIIKVTVSDTGCGIEQQVLKNIFDGLKYRQDSP
||..|.||..| |.|||.|||| |      .|.|.|..|  .|.                  ..   ..|...|.|||||. .. .|.||. . . .|..
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

QQSYNFYMDSTKKRSISNSKEQQRK-LNTEGVGLGLTIANNIAKGLG------GNRKIEVQSQLGKGSTFSFYIVNR
 |     |       |......|.| .|..|.||||||.||.|||||      |||.|.|||. |||||||||| |.
-Q-----M-------IKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 4112.AA HATPase_c 581-727 23 1.2e-20 75.78 SMART 1-130 (130) Show / Hide 
Range on Protein: 581-727
Range on HMM: 1-130/130
Sequence Identity: 23% (40 aa)

SDEMRVKQVVISLLSNAIKFTQY--------------GSISINVDCILLHNPPQAATEIIKVTVSDTGCGIEQ------QVLKNIFDGLKYRQDSPQQSY
 |..|..||.. ||.||||.|.               | |.. |.                .||.|.|.|| .      .....||.      |||    
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPS---

NFYMDSTKKRSISNSKEQQRKLNTEG--VGLGLTIANNIAKGLGGNRKIEVQSQLGKGSTFSFYIVNRS
              .....|  ...|   ||||.|...|.. .||   |.|.      .||.|..  . 
-------------RMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER
Kinase 4112.AA HATPase_c 581-726 26 2.5e-20 72.98 Pfam 1-120 (120) Show / Hide 
Range on Protein: 581-726
Range on HMM: 1-120/120
Sequence Identity: 26% (41 aa)

SDEMRVKQVVISLLSNAIKFTQY-GSISINVDCILLHNPPQAATEIIKVTVSDTGCGIEQ------QVLKNIFD-GLKYRQDSPQQSYNFYMDSTKKRSI
 |. |..|||  |..||||.|.  | |.. |.            . . .||.|.|.||        ... .||. . ....|                  
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD------------------

SNSKEQQRKLNTEG--VGLGLTIANNIAKGLGGNRKIEVQSQLGKGSTFSFYIVNR
       |  ...|   ||||.|.. |.. .||   |.|.|. |.|.||.|..  .
------SR-RKYGGGLTGLGLYICRRIVEQHGGT--IWVESEPGGGTTFTFTLPLE
REC 4112.AA REC 1077-1201 23 3.4e-24 87.62 SMART 1-150 (150) Show / Hide 
Range on Protein: 1077-1201
Range on HMM: 1-150/150
Sequence Identity: 23% (38 aa)

SNILIVDDN----QFNLHALQ------LKLKNYDFI--------IEVANSGI-------EAISKVQEKFEKSNCCK-----QHRLIFMDIDMP-------
 .||||||.    . ....|.      . |.  ..         ...| .|        ||. ..||.  |          .  ||.||| ||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IKNGYQTTKEIINFYNNQKVKPTIISACTAYIQESEVKQAKESGMKYYITKPVATEQLEEVL
  .|......|             | ..||. .|. . .| |.|.  |||||.  |.| ...
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 4112.AA Response_reg 1079-1202 28 3.6e-19 71.24 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1079-1202
Range on HMM: 1-115/115
Sequence Identity: 28% (36 aa)

ILIVDDNQFNLHALQLKLK-NYDF-IIEVANSGIEAISKVQEKFEKSNCCKQHRLIFMDIDMPIKNGYQTTKEI-INFY-NNQKVKPTIISACTAYIQES
.|||||.. .. .|.  |.  ... ....| .| ||. ..||.         . ||.|||.||  .|......|  . .  .     | | .|||. .|.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH--------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ-----TPIIMCTAHGDED

EVKQAKESGMKYYITKPVATEQLEEVLF
 . .| . |. .|||||.. ..| . . 
DAVEALQAGANDYITKPFDPDELHAAIR