Gene 25684 (Tetrahymena)
25684
Sequence
Protein domains of 25684.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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HisKA | 25684.AA | HisKA | 795-863 | 32 | 3e-13 | 49.15 | Pfam | 1-69 (69) | Show / Hide |
Range on Protein: 795-863 Range on HMM: 1-69/69 Sequence Identity: 32% (23 aa) DKMRIFASLSHELRTPLNCSISMLEVIRENVEQINPEL-IEEYLNPALFSNKLLLNQINDLLDYVQMDSG | . .|..||||||||. . ..|.... .. .|| ..|||. .. . . ....||||||. ....| AKRQFLANMSHELRTPLTAIRGYAELLQD-YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG |
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HisKA | 25684.AA | HisKA | 795-863 | 25 | 3.4e-13 | 51.07 | SMART | 1-89 (89) | Show / Hide |
Range on Protein: 795-863 Range on HMM: 1-89/89 Sequence Identity: 25% (23 aa) DKMRIFASLSHELRTPLNCSISMLEVIRENV--------EQINPELI------------EEYLNPALFSNKLLLNQINDLLDYVQMDSG | . .|..||||||||. . ..|...... .|| . .|||. .. . . ....||||||. ....| AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG |
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Kinase | 25684.AA | HisK | 910-1032 | 35 | 2.5e-61 | 210.08 | In-house | 1-164 (164) | Show / Hide |
Range on Protein: 910-1032 Range on HMM: 1-164/164 Sequence Identity: 35% (58 aa) SDPNRIRQILLNFLSNSLKFTKKG------YIEIGITLFDNK------------------------KGLLKVYVKDTGIGITKENLDTIFDFCGKV---- ||||||.|||.|..||.||||.|| ||.| ....... |.|....|.|||.|...|.. ||...|.. SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH -----NYNQKDQHLNRQGCGLGLTISNSIAKGLVKNGE--DDGGIKVESDYGHGSTFSILIQDM ..|.... .|..||||||||.|..|||| .... . .||.|.|..|.|||||..|.. QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN |
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Kinase | 25684.AA | HATPase_c | 910-1032 | 25 | 2.3e-19 | 69.63 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 910-1032 Range on HMM: 1-120/120 Sequence Identity: 25% (35 aa) SDPNRIRQILLNFLSNSLKFTKK-GYIEIGITLFDNKKGLLKVYVKDTGIGITK------ENLDTIFD-------FCGKVNYNQKDQHLNRQG--CGLGL ||.|..|...|...|..|.|.. | |.. .. | . . . |.|.|.||.. |....||. ...| |||| GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD---------SR-RKYGGGLTGLGL TISNSIAKGLVKNGEDDGGIKVESDYGHGSTFSILIQDM .|.. |.. . |. | ||| |.|.||.. . YICRRIVEQHG--GT----IWVESEPGGGTTFTFTLPLE |
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Kinase | 25684.AA | HATPase_c | 910-1033 | 22 | 8.6e-18 | 66.35 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 910-1033 Range on HMM: 1-130/130 Sequence Identity: 22% (34 aa) SDPNRIRQILLNFLSNSLKFTKKGY------------IEIGITLFDNKKGLLKVYVKDTGIGITK------ENLDTIFDFCGKVNY-----NQKDQHLNR ||.|.||.|.| |.|..|.|..|. .| ... . |.|.|.||.. | ...||. ... .. . .. GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY QG--CGLGLTISNSIAKGLVKNGEDDGGIKVESDYGHGSTFSILIQDMS .| ||||.|...|.. . .|. |.|| .||.. . GGGLTGLGLSICKRIVEQH--GGT----IWVE------TTFTFTLPLER |
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REC | 25684.AA | REC | 1419-1545 | 21 | 1.7e-18 | 68.7 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 1419-1545 Range on HMM: 1-150/150 Sequence Identity: 21% (36 aa) PQFMIVDDN----QFNTYALS------KILGQYFFT--------FQCLSDGF-------SAIEEVQSLYQKSCCKA------PKIIFMDIEMP------- . .||||. . . .|. ..| . .. . || |.| .|.. .| | .|.|||.|| MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG MKNGYETAVEINQFYEQVALPVQYQPIIIACTAYVGQEDVDAAMQSGMKDFINKPILKNGLESLI .|.|.. .| ||..||. . ||. .|...|. |.| ||. . | | GMDGIELCRRIR--------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
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Response_reg | 25684.AA | Response_reg | 1421-1546 | 30 | 6.9e-11 | 41.56 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 1421-1546 Range on HMM: 1-115/115 Sequence Identity: 30% (39 aa) FMIVDDNQFNTYALSKILG-QYFF-TFQCLSDGFSAIEEVQSLYQKSCCKAPKIIFMDIEMPMKNGYETAVEI-NQFY-EQVALPVQYQPIIIACTAYVG .||||.. . .| .|| .. . .|| .|.| .| . | .|.|||.|| .|.|.. .| | . | . ||.|||. VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ--------TPIIMCTAHGD QEDVDAAMQSGMKDFINKPILKNGLESLIL .|. .|.| |. |.| ||. .. | | EDDAVEALQAGANDYITKPFDPDELHAAIR |