Gene 23233 (Tetrahymena)

23233

Species: Tetrahymena
Alias: 1090, PreTt23233, 23233, 135.m00084, TTHERM_00797940
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
23233.AA Protein None 3047 None Fasta, JSON
23233.kin_dom Protein Kinase Domain None 116 None Fasta, JSON
23233.NA RNA None 9144 None Fasta, JSON

Protein domain

Protein domains of 23233.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 23233.AA HisKA 2237-2302 25 1.3e-15 59.1 SMART 1-89 (89) Show / Hide 
Range on Protein: 2237-2302
Range on HMM: 1-89/89
Sequence Identity: 25% (23 aa)

NKSQMLSQVAHEFRTPLNCIISMMDLASI-----------TNPQSQI------------QQYLKPALTSAKQLNSMVNDLLDLAQLKAG
 |.|.|. ..||.||||. |. . .|.             . .  |.            ..||. .. .|.......||||||... ||
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 23233.AA HisKA 2237-2302 31 1.4e-15 57.23 Pfam 1-69 (69) Show / Hide 
Range on Protein: 2237-2302
Range on HMM: 1-69/69
Sequence Identity: 31% (22 aa)

NKSQMLSQVAHEFRTPLNCIISMMDLASI-TNPQSQI--QQYLKPALTSAKQLNSMVNDLLDLAQLKAG
 |.|.|. ..||.||||. |. . .|.   |.  ..   ..||. .. .|.......|||||.... ||
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 23233.AA HisK 2349-2464 35 2.8e-58 199.94 In-house 1-164 (164) Show / Hide 
Range on Protein: 2349-2464
Range on HMM: 1-164/164
Sequence Identity: 35% (59 aa)

SDPNRLRQIIINLVGNSLKFTKKG------SITIKASLISTK--------------------------VIKISIIDTGIGIKEEDMANLFQAFGKIAG--
|||||..||.|||..|.||||.||      .|.||...|.|.                          .|.||..|||.|..||.. ..|..||.| .  
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

--------QEQKQLNPNGVGLGLMISHVLAKNLGEG------EGLKVESQVGIGTEFYFEIVNN
        ...|..|..|.||||.|.  ||| ||.        |..|.|.||.|..|.|.| ||
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 23233.AA HATPase_c 2349-2465 24 1.3e-23 85.64 SMART 1-130 (130) Show / Hide 
Range on Protein: 2349-2465
Range on HMM: 1-130/130
Sequence Identity: 24% (35 aa)

SDPNRLRQIIINLVGNSLKFTKK--------------GSITIKASLISTKVIKISIIDTGIGIKE------EDMANLFQAFGKIAGQE------QKQLNP
 ||.||||...||..|..|.|..              | ||....        |...|.|.|| .      ||. ..|..|.. ....      ..  . 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

NG--VGLGLMISHVLAKNLGEGEGLKVESQVGIGTEFYFEIVNNL
 |   |||| |.. ... .|    ..||      |.|.|..   .
GGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER
Kinase 23233.AA HATPase_c 2349-2464 31 2e-23 83.78 Pfam 1-120 (120) Show / Hide 
Range on Protein: 2349-2464
Range on HMM: 1-120/120
Sequence Identity: 31% (39 aa)

SDPNRLRQIIINLVGNSLKFTKK-GSITIKASLISTKVIKISIIDTGIGIKE------EDMANLFQAFGKIAGQEQKQLNPNG--VGLGLMISHVLAKNL
 ||.||.|.. |||.|..|.|.. | ||....      . |...|.|.|| .      ||....|..|..  ..     .  |   |||| |.. ... .
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-SR-RKYGGGLTGLGLYICRRIVEQH

GEGEGLKVESQVGIGTEFYFEIVNN
| |. . |||..| ||.| |..   
G-GT-IWVESEPGGGTTFTFTLPLE
REC 23233.AA REC 2914-3036 20 6.4e-24 86.7 SMART 1-150 (150) Show / Hide 
Range on Protein: 2914-3036
Range on HMM: 1-150/150
Sequence Identity: 20% (33 aa)

VEILTIDDN----EFNNMVLK------MHIERLIRA-------RVHCAIDAH-------DALSKLQEQYTKTK-------SGFDLIFLDLSMP-------
  || .||.    . . ..|.      .  |..           |..| |.        .|| .|||. .|         . .|||..|. ||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

EIDGYGTFSMIKDFCNEKRINQNVVACTGYSSLEEKDKCIDIGMVDYILKPIEIPKLKEVL
..||. .  .|.           ....|.... | . .... |..|||.||...  | ...
GMDGIELCRRIR----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 23233.AA Response_reg 2916-3037 24 2e-17 64.99 Pfam 1-115 (115) Show / Hide 
Range on Protein: 2916-3037
Range on HMM: 1-115/115
Sequence Identity: 24% (30 aa)

ILTIDDNEFNNMVLKMHIERLIRA-RVHCAIDAHDALSKLQEQYTKTKSGFDLIFLDLSMPEIDGYGTFSMI-KDFCNEKRINQNVVACTGYSSLEEKDK
.| .||.. . ..|.  .|.     .|  | |...|| ..||.       .|||..|..||..||. ....| .    .  .   ...||...... . .
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQT--PIIMCTAHGDEDDAVE

CIDIGMVDYILKPIEIPKLKEVLS
... |..|||.||. . .|.. . 
ALQAGANDYITKPFDPDELHAAIR