Gene 22512 (Tetrahymena)

22512

Species: Tetrahymena
Alias: 1120, PreTt22512, TTHERM_00470980, 3686.m00059, 56.m00216, 22512
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
22512.AA Protein None 1761 None Fasta, JSON
22512.kin_dom Protein Kinase Domain None 119 None Fasta, JSON
22512.NA RNA None 5286 None Fasta, JSON

Protein domain

Protein domains of 22512.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 22512.AA HisKA 549-616 12 0.000224 15.71 SMART 1-89 (89) Show / Hide 
Range on Protein: 549-616
Range on HMM: 1-89/89
Sequence Identity: 12% (11 aa)

ISYRIFQTLSHEFGTYMNIISNITENALE---------DDRISIDLK------------KDYFRIINTNSILLENVVKDMRDFFSIMNQ
   . . ..|||. | .. |.  .| ...         ..  . .              ..|...|   .  ... . |..|.  | ..
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 22512.AA HisK 663-781 28 4.6e-41 142.73 In-house 1-164 (164) Show / Hide 
Range on Protein: 663-781
Range on HMM: 1-164/164
Sequence Identity: 28% (46 aa)

SDESFIKQILSNFISNSLKFTLQG------YINIYLFKES--------------------------EKYIRLEVEDSGIGMSSEECERLKGMLKNG----
||.. ||||| |.|||.|||| .|      || | . . .                          ...|.  |.|.|.||. |. . .. |. |.    
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

------FSDQKISKNSVGLGFGLLVSNNLARLIGNSI---KKQAIYFDSSPQGGSRFWILIRTT
      |. |... |. | |.|| ..||||...|...   ... |.. | .  || |...|. .
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 22512.AA HATPase_c 663-781 20 8.9e-19 67.59 Pfam 1-120 (120) Show / Hide 
Range on Protein: 663-781
Range on HMM: 1-120/120
Sequence Identity: 20% (27 aa)

SDESFIKQILSNFISNSLKFTLQ-GYINIYLFKESEKYIRLEVEDSGIGMSS------EECERLKG-------MLKNGFSDQKISKNSVG--LGFGLLVS
 |. ...|...|...|..|.| . | | . . ..   ..|..|||.|.|..       |. .|.         .            .. |   |.|| ..
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD--------SR-RKYGGGLTGLGLYIC

NNLARLIGNSIKKQAIYFDSSPQGGSRFWILIRTT
. .... | .     | ..|.|.||..|.. .  .
RRIVEQHGGT-----IWVESEPGGGTTFTFTLPLE
Kinase 22512.AA HATPase_c 663-782 16 2.4e-16 61.53 SMART 1-130 (130) Show / Hide 
Range on Protein: 663-782
Range on HMM: 1-130/130
Sequence Identity: 16% (24 aa)

SDESFIKQILSNFISNSLKFTLQ--------------GYINIYLFKESEKYIRLEVEDSGIGMSS----EECERLKGMLKNGFSDQK---------ISKN
 |. ...|.|.| ..|..|.| .              | | . .        |..|||.|.|..      . | .. ..  ...  .          | .
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSI-EDIPRIFEPFYRTDDSPSRMCPDSRSRK

SVG--LGFGLLVSNNLARLIGNSIKKQAIYFDSSPQGGSRFWILIRTTT
. |   | || ........ | .|. .           ..|.. .. ..
YGGGLTGLGLSICKRIVEQHGGTIWVE-----------TTFTFTLPLER
REC 22512.AA REC 1622-1754 24 3.7e-31 110.74 SMART 1-150 (150) Show / Hide 
Range on Protein: 1622-1754
Range on HMM: 1-150/150
Sequence Identity: 24% (40 aa)

KKILLVDDE----IFNIFSLK------LIFQKFGLS------DNILEAYNGQ-------QAIQVLLNQQ-NKKQIPINQEGYQIGMIIMDVNMP------
..||.|||.      .   |.      ....| |        ... || .|.       .|.. | ... .| . ...   ...  ||||..||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-IMNGIECTKYIRELENNNLIDYSPNIIGYTAYSDSQTRNMCFDAGMDDLLLKPSRRDDFIAII
  |.||| .. ||             ||  ||..| ..|  ...||.|| ..|| ......| |
GGMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 22512.AA Response_reg 1624-1755 27 2e-25 93.65 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1624-1755
Range on HMM: 1-115/115
Sequence Identity: 27% (37 aa)

ILLVDDEIFNIFSLKLIFQ-KFGLSDNILEAYNGQQAIQVLLNQQNKKQIPINQEGYQIGMIIMDVNMPIMNGIECTKYI-RELE-NNNLIDYSPNIIGY
.|.|||.  .   |. |.. | |.  .. ||..|..|.. . ...             ...||||.||| |.|.| ...| |...  .      . ||  
VLIVDDHPLMREGLRQILEQKEGY-EVVAEADDGEEALEWWQEHH-------------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ------TPIIMC

TAYSDSQTRNMCFDAGMDDLLLKPSRRDDFIAIIE
||..| ...  ...||..| ..||. .|. .|.|.
TAHGDEDDAVEALQAGANDYITKPFDPDELHAAIR