Gene 21980 (Tetrahymena)

21980

Species: Tetrahymena
Alias: 1026, 21980, TTHERM_00896090, PreTt21980, 159.m00088
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
21980.AA Protein None 1466 None Fasta, JSON
21980.kin_dom Protein Kinase Domain None 57 None Fasta, JSON
21980.NA RNA None 4401 None Fasta, JSON

Protein domain

Protein domains of 21980.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 21980.AA HisKA 650-718 22 3.1e-09 35.15 Pfam 1-69 (69) Show / Hide 
Range on Protein: 650-718
Range on HMM: 1-69/69
Sequence Identity: 22% (16 aa)

FKQKIISSLAHELKTPLNSIISQINQLLLNRHEESVNL-KSKDIQILKSSANLLNYKIEDLLNYSMYMKG
 |.. .....|||.|||..|.  .  |.  ... .      . .......|. ..  |.||| .|    |
AKRQFLANMSHELRTPLTAIRGYAELLQD-YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 21980.AA HisKA 650-718 17 3.8e-08 34.3 SMART 1-89 (89) Show / Hide 
Range on Protein: 650-718
Range on HMM: 1-89/89
Sequence Identity: 17% (16 aa)

FKQKIISSLAHELKTPLNSIISQINQLLL--------NRHEESVNLK------------SKDIQILKSSANLLNYKIEDLLNYSMYMKG
 |.. .....|||.|||..|.  .  |.          ... .                 . .......|. ..  |.||| .|    |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 21980.AA HisK 890-944 29 4.4e-21 72.66 In-house 1-87 (164) Show / Hide 
Range on Protein: 890-944
Range on HMM: 1-87/164
Sequence Identity: 29% (26 aa)

SDKKKLICILTNLLTNALKFTFKG------GISFTVNQID--------------------------KYNFEFSVSDTGIGIEQKLVK
||. ..  || ||..||||||.||       |.. |.||.                          |.....||.|||.|. ....|
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQK
Kinase 21980.AA HATPase_c 890-946 28 4.5e-09 33.82 Pfam 1-63 (120) Show / Hide 
Range on Protein: 890-946
Range on HMM: 1-63/120
Sequence Identity: 28% (18 aa)

SDKKKLICILTNLLTNALKFTFK-GGISFTVNQIDKYNFEFSVSDTGIGIEQ------KLVKRM
 |   |  ...||..||.|.| . | |. .| . |  . ...|.|.|.||        ... |.
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRI
Kinase 21980.AA HATPase_c 890-966 16 0.000989 5.94 SMART 1-130 (130) Show / Hide 
Range on Protein: 890-966
Range on HMM: 1-130/130
Sequence Identity: 16% (23 aa)

SDKKKLICILTNLLTNALKFTFK--------------GGISFTVNQIDKYNFEFSVSDTGIGIEQ-----------------------------------
 | . |  .|.|||.||.|.| .              | |. .|.       ...|.|.|.|| .                                   
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

-------------KLVKRMNN-VNIEDYDTIFMNDQEDES
             ..|....  . .|   | |      | 
GGGLTGLGLSICKRIVEQHGGTIWVE---TTFTFTLPLER
Kinase 21980.AA HisK 1140-1204 18 1.7e-08 27.28 In-house 89-164 (164) Show / Hide 
Range on Protein: 1140-1204
Range on HMM: 89-164/164
Sequence Identity: 18% (14 aa)

LQNQKQQKNQH------YKSQPSLYNFQRNCGIGIKIVKILTSQLSSNT-----QNLKIKSKENLGSTFTFTLEDQ
. .. .....       .... .  | |  ||.|  | ..|  .|...      ......|... ||||.| ....
IFKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 21980.AA HATPase_c 1165-1204 30 0.0917 8.38 Pfam 84-120 (120) Show / Hide 
Range on Protein: 1165-1204
Range on HMM: 84-120/120
Sequence Identity: 30% (12 aa)

GIGIKIVKILTSQLSSNTQNLKIKSKENLGSTFTFTLEDQ
|.|  |.. .  |.      . . |... |.||||||  .
GLGLYICRRIVEQHGGT---IWVESEPGGGTTFTFTLPLE
REC 21980.AA REC 1342-1459 26 2.8e-31 111.13 SMART 1-150 (150) Show / Hide 
Range on Protein: 1342-1459
Range on HMM: 1-150/150
Sequence Identity: 26% (43 aa)

KRILLVDDM----PFNIQILK-----NYLKGVENLE--------IKEAFNGM-------SAIEQVQQE-------------KFDLILMDINMP-------
.|||.|||     | . ..|.      .|   |. |        . || .|         |.|..|..             ..|||.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

LMDGIEATFKITELIKSNQIQPVPIIIVSAYTAIQDIQNSLKSGAAGHVSKPISIKSLISEI
 |||||.. .|            |||...|..  .|..  |..|| . ..||.... |.  |
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 21980.AA Response_reg 1344-1460 34 3.6e-31 114.22 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1344-1460
Range on HMM: 1-115/115
Sequence Identity: 34% (41 aa)

ILLVDDMPFNIQILKNYLKGVENL-EIKEAFNGMSAIEQVQQEKFDLILMDINMPLMDGIEATFKI-TELIKSNQIQPVPIIIVSAYTAIQDIQNSLKSG
.|.||| | . ..|...|.  | . .. || .| .|.|..|....|||.|||||| |||.|.. .|  ..  . |   .|||...|.  ..|..  |. |
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRRQHP-HPQ---TPIIMCTAHGDEDDAVEALQAG

AAGHVSKPISIKSLISEIN
| ....||...  |. .|.
ANDYITKPFDPDELHAAIR