Gene 14557 (Tetrahymena)

14557

Species: Tetrahymena
Alias: TTHERM_00039220, 14557, 2.m02173, 3825.m02924, 160, PreTt14557
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
14557.AA Protein None 1220 None Fasta, JSON
14557.kin_dom Protein Kinase Domain None 114 None Fasta, JSON
14557.NA RNA None 3663 None Fasta, JSON

Protein domain

Protein domains of 14557.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 14557.AA HisKA 529-603 34 1.4e-11 43.37 Pfam 1-69 (69) Show / Hide 
Range on Protein: 529-603
Range on HMM: 1-69/69
Sequence Identity: 34% (26 aa)

YKNRMLASVSHELRTPLNCSIQLLQSLLQRDQEYQNMTPLDGEI-KEMIIKPALNSNLLLLNIINDILDYGQINQG
 |...||..||||||||. .|... .|||.       |.|| |   . ... ....   ....|||.||. .| .|
AKRQFLANMSHELRTPLT-AIRGYAELLQD------YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 14557.AA HisKA 529-603 30 8.5e-10 39.79 SMART 1-89 (89) Show / Hide 
Range on Protein: 529-603
Range on HMM: 1-89/89
Sequence Identity: 30% (27 aa)

YKNRMLASVSHELRTPLNCSIQLLQSLLQRDQE---YQNMTPLDGEIK------------EMIIKPALNSNLLLLNIINDILDYGQINQG
 |...||..||||||||. .|... .|||....   |.  |.|| |              . ... ....   ....|||.||. .| .|
AKRQFLANMSHELRTPLT-AIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 14557.AA HisK 650-763 35 7.8e-54 185.16 In-house 1-164 (164) Show / Hide 
Range on Protein: 650-763
Range on HMM: 1-164/164
Sequence Identity: 35% (59 aa)

SDQGRLKQVLLNLLSNSLKFTDAG------TIRVNSV--------------------------VENFDLIRIDVSDTGCGIPEDNLEKVLQAFGNK----
||. |.||.|.||.||.||||. |      .|...                            ... .||.|.|.|||||.||....|  ..|||.    
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

--------STGKFLNTIGAGFGMSIANNLALGLG------GNRSIQIQSKVKEGSTFTFYVINR
           |..|. |.|.| .|.|||| |||      |||.||.||.|..||||.||. |.
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 14557.AA HATPase_c 650-763 29 2.3e-26 94.02 Pfam 1-120 (120) Show / Hide 
Range on Protein: 650-763
Range on HMM: 1-120/120
Sequence Identity: 29% (36 aa)

SDQGRLKQVLLNLLSNSLKFTDA-GTIRVNSVVENFDLIRIDVSDTGCGIPE------DNLEKVLQAFGNKST-GKFLNTIG--AGFGMSIANNLALGLG
 |. ||.||..||..|..|.| . |.|.|    .. | .|| |.|.|.|||.      .........|.  .  .   .. |   |.|..|.. ..  .|
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHG

GNRSIQIQSKVKEGSTFTFYVINR
|   |...|....|.||||..  .
GT--IWVESEPGGGTTFTFTLPLE
Kinase 14557.AA HATPase_c 650-764 24 2.7e-24 87.97 SMART 1-130 (130) Show / Hide 
Range on Protein: 650-764
Range on HMM: 1-130/130
Sequence Identity: 24% (36 aa)

SDQGRLKQVLLNLLSNSLKFTDA--------------GTIRVNSVVENFDLIRIDVSDTGCGIPE------DNLEKVLQAFGNKST--------GKFLNT
 |. ||.|||.|||.|..|.|..              |.|.|          || |.|.|.|||.      . .......|.  .         ..  ..
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

IG--AGFGMSIANNLALGLGGNRSIQIQSKVKEGSTFTFYVINRA
 |   | |.||.....  .||   |...      .||||..  ..
GGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER
REC 14557.AA REC 1088-1212 20 2.1e-23 85.01 SMART 1-150 (150) Show / Hide 
Range on Protein: 1088-1212
Range on HMM: 1-150/150
Sequence Identity: 20% (34 aa)

SKILVVDDN----DFNLYAIQ------MCLKQYGFV--------SEKATSGF-------MAIDKIKQKLKQSDCCL-----TYKLIFMDIDMP-------
 .||.|||.      .. ...      . |.. |.          . | .|         |....... .. .  .      . ||.||| ||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IKDGYETTKNILQYFQKKNIPPPKISACTAYVQEKERKKAFDCGMSYYLTKPINSFELENIL
  ||.|... |            .| ..||. .|  | .|.. |.  |.|||..  ||   .
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 14557.AA Response_reg 1090-1213 28 2.7e-17 64.53 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1090-1213
Range on HMM: 1-115/115
Sequence Identity: 28% (36 aa)

ILVVDDNDFNLYAIQMCLK-QYGF-VSEKATSGFMAIDKIKQKLKQSDCCLTYKLIFMDIDMPIKDGYETTKNI-LQYFQKKNIPPPKISACTAYVQEKE
.|.|||.. .. ... .|. ..|. | . |..|  |.... |...       . ||.|||.||  ||.|... |  |   . .   ..| .|||. .|  
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW-QEHH-------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ---TPIIMCTAHGDEDD

RKKAFDCGMSYYLTKPINSFELENILK
. .|.. |. .|.|||..  || ....
AVEALQAGANDYITKPFDPDELHAAIR