Gene 10845 (Tetrahymena)

10845

Species: Tetrahymena
Alias: 153, 10845, TTHERM_00717470, 114.m00080, PreTt10845, 3827.m00925
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
10845.AA Protein None 1133 None Fasta, JSON
10845.kin_dom Protein Kinase Domain None 126 None Fasta, JSON
10845.NA RNA None 3402 None Fasta, JSON

Protein domain

Protein domains of 10845.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 10845.AA HisKA 357-427 30 6.6e-11 41.0 Pfam 1-69 (69) Show / Hide 
Range on Protein: 357-427
Range on HMM: 1-69/69
Sequence Identity: 30% (22 aa)

DKFKLFATLSHELRTPLNCSISMLEVLKD--ELSQKENNKFCIEEYINPALFSNKLLLNQINDILDYVQMDCG
 | ...|..||||||||.  . ..|.|.|  .|. ...    ..||.. .. . . ....|||.||. ... |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQM----RREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 10845.AA HisKA 357-427 24 1e-09 39.53 SMART 1-89 (89) Show / Hide 
Range on Protein: 357-427
Range on HMM: 1-89/89
Sequence Identity: 24% (22 aa)

DKFKLFATLSHELRTPLNCSISMLEVLKD-----------ELSQKENNKFC-------IEEYINPALFSNKLLLNQINDILDYVQMDCG
 | ...|..||||||||.  . ..|.|.|           .|. ... .         ..||.. .. . . ....|||.||. ... |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 10845.AA HisK 474-596 34 2.8e-55 189.98 In-house 1-164 (164) Show / Hide 
Range on Protein: 474-596
Range on HMM: 1-164/164
Sequence Identity: 34% (57 aa)

SDPNRIRQIILNFLSNSLKFTKSGG-----HIELGYQQIS--------------------------KDIYKIYVKDSGIGITLENQQKIFGFCNKIK---
||||||.||..|..||.||||. ||     .|.. ..||.                          |....|.|.|.|.|.. |.|.||| ....|.   
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----YQSKEEEQLNYQGCGLGLTISNQLAEGLITSDN--FKGGISVESEYGVGSIFSILVEDL
     .........| .||||||||.|.||.||  ..|   ..||.|.||.|.||.||..... 
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 10845.AA HATPase_c 474-596 28 1.4e-18 66.94 Pfam 1-120 (120) Show / Hide 
Range on Protein: 474-596
Range on HMM: 1-120/120
Sequence Identity: 28% (39 aa)

SDPNRIRQIILNFLSNSLKFTKSGGHIELGYQQISKDIYKIYVKDSGIGITL------ENQQKIFG-------FCNKIKYQSKEEEQLNYQG--CGLGLT
 ||.|..|...|...|..|.|..||||..   .   |   | |.|.|.||.       |....||                       .|.|   ||||.
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD----------SR-RKYGGGLTGLGLY

ISNQLAEGLITSDNFKGGISVESEYGVGSIFSILVEDL
|.....|       . | |.|||| | |. |.. .   
ICRRIVEQ------HGGTIWVESEPGGGTTFTFTLPLE
Kinase 10845.AA HATPase_c 474-597 22 1.6e-16 62.11 SMART 1-130 (130) Show / Hide 
Range on Protein: 474-597
Range on HMM: 1-130/130
Sequence Identity: 22% (35 aa)

SDPNRIRQIILNFLSNSLKFTKS-------------GGHIELGYQQISKDIYKIYVKDSGIGITL------ENQQKIFGFCNKIKYQSKE--------EE
 ||.|.||...| |.|..|.|..             ||.|..           | |.|.|.||.       | ...||       |. ..        . 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIF----EPFYRTDDSPSRMCPDSR

QLNYQG--CGLGLTISNQLAEGLITSDNFKGGISVESEYGVGSIFSILVEDLN
  .|.|   ||||.|.....| .  .      |.||      . |.. .    
SRKYGGGLTGLGLSICKRIVEQHGGT------IWVE------TTFTFTLPLER
REC 10845.AA REC 998-1122 20 2.4e-22 81.47 SMART 1-150 (150) Show / Hide 
Range on Protein: 998-1122
Range on HMM: 1-150/150
Sequence Identity: 20% (34 aa)

PQIMIVDDN----QFNLYALQ------KIIQQFQFN--------LTTLSDGD-------QAIEAIKNQ--YYENCC----PSPNMILMDIEMP-------
. |.||||.    . .. .|.      .. ..  .          ..  ||.       .|.|.....  ..|       . |  |.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IKNGYETVKEIIQFYKTEQYKSIPVIVACTAYVGQEDYEKSIESGMDDFINKPILKMAFKNLI
  .|.|....|              |...||. . || .. .|.|.||.| ||.    .   |
GMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 10845.AA Response_reg 1000-1123 25 1.6e-19 72.49 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1000-1123
Range on HMM: 1-115/115
Sequence Identity: 25% (32 aa)

IMIVDDNQFNLYALQKIIQ-QFQF-NLTTLSDGDQAIEAIKNQYYENCCPSPNMILMDIEMPIKNGYETVKEI-IQFY-KTEQYKSIPVIVACTAYVGQE
..||||.. .. .|..|.. . .. . .. .|| .|.| ....        | .|.|||.||  .|.|. ..|  | .  .      . |..|||.   .
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ------TPIIMCTAHGDED

DYEKSIESGMDDFINKPILKMAFKNLIQ
| .. .. |..|.| ||. . . .. |.
DAVEALQAGANDYITKPFDPDELHAAIR